scholarly journals Development of a High-Throughput Low-Cost Approach for Fabricating Fully Drawn Paper-Based Analytical Devices Using Commercial Writing Tools

Chemosensors ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 178
Author(s):  
Varvara Pagkali ◽  
Eleftheria Stavra ◽  
Dionysios Soulis ◽  
Anastasios Economou
Keyword(s):  
Chemical Resistance ◽  
Low Cost ◽  
Electrochemical Sensing ◽  
Structural Rigidity ◽  
Fit For Purpose ◽  
Multiple Loading ◽  
Number Of Passes ◽  
Writing Tools ◽  
Analytical Utility ◽  
Fabrication Parameters

This work reports the development and optimization of a rapid and low-cost pen-on-paper plotting approach for the fabrication of paper-based analytical devices (PADs) using commercial writing stationery. The desired fluidic patterns were drawn on the paper substrate with commercial marker pens using an inexpensive computer-controlled x–y plotter. For the fabrication of electrochemical PADs, electrodes were further deposited on the devices using a second x–y plotting step with commercial writing pencils. The effect of the fabrication parameters (type of paper, type of marker pen, type of pencil, plotting speed, number of passes, single- vs. double-sided plotting), the chemical resistance of the plotted devices to different solvents and the structural rigidity to multiple loading cycles were assessed. The analytical utility of these devices is demonstrated through application in optical sensing of total phenols using reflectance calorimetry and in electrochemical sensing of paracetamol and ascorbic acid. The proposed manufacturing approach is simple, low cost, flexible, rapid and fit-for-purpose and enables the fabrication of sub-“one-dollar” PADs with satisfactory mechanical and chemical resistance and good analytical performance.

scholarly journals Molecularly Imprinted Polymers Combined with Electrochemical Sensors for Food Contaminants Analysis

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4607
Author(s):  
Dounia Elfadil ◽  
Abderrahman Lamaoui ◽  
Flavio Della Pelle ◽  
Aziz Amine ◽  
Dario Compagnone
Keyword(s):  
Food Safety ◽  
Molecularly Imprinted Polymers ◽  
Electrochemical Sensors ◽  
Low Cost ◽  
Electrochemical Analysis ◽  
Ease Of Use ◽  
Electrochemical Sensing ◽  
Food Contaminants ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

Detection of relevant contaminants using screening approaches is a key issue to ensure food safety and respect for the regulatory limits established. Electrochemical sensors present several advantages such as rapidity; ease of use; possibility of on-site analysis and low cost. The lack of selectivity for electrochemical sensors working in complex samples as food may be overcome by coupling them with molecularly imprinted polymers (MIPs). MIPs are synthetic materials that mimic biological receptors and are produced by the polymerization of functional monomers in presence of a target analyte. This paper critically reviews and discusses the recent progress in MIP-based electrochemical sensors for food safety. A brief introduction on MIPs and electrochemical sensors is given; followed by a discussion of the recent achievements for various MIPs-based electrochemical sensors for food contaminants analysis. Both electropolymerization and chemical synthesis of MIP-based electrochemical sensing are discussed as well as the relevant applications of MIPs used in sample preparation and then coupled to electrochemical analysis. Future perspectives and challenges have been eventually given.

Deposition of Bead Arrays With Variable Diameter by Self-Focusing of Electrohydrodynamic Jets

2017 ◽  
Author(s):  
Nicolas Martinez-Prieto ◽  
Gabriela Fratta ◽  
Jian Cao ◽  
Kornel Ehmann
Keyword(s):  
Low Cost ◽  
Three Dimensional ◽  
Deposition Process ◽  
Direct Writing ◽  
Variable Diameter ◽  
Self Focusing ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Number Of Passes ◽  
Bead Arrays

Electrohydrodynamic processes were used for direct-writing of bead arrays with controllable bead sizes. Experiments were conducted to align layers of bead-on-string structures in an effort to create three-dimensional patterns. The results show that the jet focuses on previously deposited droplets allowing for the selective deposition of material over already deposited patterns. Jet attraction to already deposited solutions on the substrate is attributed to the charge transport at the liquid ink-metal collector interface and the dielectric properties of the water/poly(ethylene oxide) solution under an electric field. The deposition process consists of 3 steps: (1) deposition of a layer of bead-on-string structures, (2) addition of extra volume to the beads by subsequent passes of the jet, and (3) evaporation of the solvent resulting in an array of beads with varying sizes. Patterns with up to 20 passes were experimentally obtained. The beads’ height was seen to be independent of the number of passes. The process reported is a simple, fast, and low-cost method for deposition of bead arrays with varying diameters.

scholarly journals PHOTOGRAMMETRY AS A PARTICIPATORY RECOVERY TOOL AFTER DISASTERS: A GROUNDED FRAMEWORK FOR FUTURE GUIDELINES

2019 ◽  
Vol XLII-2/W15 ◽  
pp. 921-928
Author(s):  
C. Pezzica ◽  
A. Piemonte ◽  
C. Bleil de Souza ◽  
V. Cutini
Keyword(s):  
Low Cost ◽  
Central Italy ◽  
Semantic Content ◽  
Ethnographic Study ◽  
Point Of View ◽  
Humanitarian Response ◽  
Central Italy Earthquake ◽  
Depth Analysis ◽  
Crowdsourced Data ◽  
Fit For Purpose

<p><strong>Abstract.</strong> This paper identifies the application domain, context of use, processes and goals of low-cost street-level photogrammetry after urban disasters. The proposal seeks a synergy between top-down and bottom-up initiatives carried out by different actors during the humanitarian response phase in data scarce contexts. By focusing on the self-organisation capacities of local people, this paper suggests using collaborative photogrammetry to empower communities hit by disasters and foster their active participation in recovery and reconstruction planning. It shows that this task may prove technically challenging depending on the specifics of the collected imagery and develops a grounded framework to produce user-centred image acquisition guidelines and fit-for-purpose photogrammetric reconstruction workflows, useful in future post-disaster scenarios. To this end, it presents an in-depth analysis of a collaborative photographic mapping initiative undergone by a group of citizen-scientists after the 2016 Central Italy earthquake, followed by the explorative processing of some sample datasets. Specifically, the paper firstly presents a visual ethnographic study of the photographic material uploaded by participants from September 2016 to November 2018 in the two Italian municipalities of Arquata del Tronto and Norcia. Secondly, it illustrates from a technical point of view issues concerning the processing of crowdsourced data (e.g. image filtering, selection, quality, semantic content and 3D model scaling) and discusses the viability of using it to enrich the pool of geo-information available to stakeholders and decision-makers. Final considerations are discussed as part of a grounded framework for future guidelines tailored to multiple goals and data processing scenarios.</p>

Advances in preparation, modification, and application of polypropylene membrane

2016 ◽  
Vol 36 (4) ◽  
pp. 329-362 ◽  
Author(s):  
Nurul F. Himma ◽  
Sofiatun Anisah ◽  
Nicholaus Prasetya ◽  
I Gede Wenten
Keyword(s):  
Thermal Stability ◽  
High Performance ◽  
Chemical Resistance ◽  
Low Cost ◽  
Comprehensive Overview ◽  
Preparation Methods ◽  
Good Thermal Stability ◽  
Polypropylene Membrane ◽  
Membrane Fabrication ◽  
Potential Applications

Abstract Polypropylene (PP) is one of the most used polymers for microporous membrane fabrication due to its good thermal stability, chemical resistance, mechanical strength, and low cost. There have been numerous studies reporting the developments and applications of PP membranes. However, PP membrane with high performance is still a challenge. Thus, this article presents a comprehensive overview of the advances in the preparation, modification and application of PP membrane. The preparation methods of PP membrane are firstly reviewed, followed by the modification approaches of PP membrane. The modifications includes hydrophilic and superhydrophobic modification so that the PP membranes become more suitable to be applied either in aqueous applications or in non-aqueous ones. The fouling resistant of hydrophilized PP membrane and the wetting resistant of superhydrophobized PP membrane are then reviewed. Finally, special attention is given to the various potential applications and industrial outlook of the PP membranes.

Intelligent analysis of maleic hydrazide using a simple electrochemical sensor coupled with machine learning

2021 ◽  
Vol 13 (39) ◽  
pp. 4662-4673
Author(s):  
Lulu Xu ◽  
Ruimei Wu ◽  
Xiaoyu Zhu ◽  
Xiaoqiang Wang ◽  
Xiang Geng ◽  
...  
Keyword(s):  
Machine Learning ◽  
Electrochemical Sensor ◽  
Maleic Hydrazide ◽  
Low Cost ◽  
Electrochemical Sensing ◽  
Flexible Electrode ◽  
Porous Graphene ◽  
Sensing Platform ◽  
Intelligent Analysis

A simple intelligent electrochemical sensing platform based on a low-cost disposable laser-induced porous graphene flexible electrode for maleic hydrazide coupled with machine learning was successfully designed.

Delivering More Fit-for-Purpose Wells with Low Cost Approach at Untapped Area Matured Field – Application of Cone Concept Statistical Approach

2021 ◽  
Author(s):  
M. Hatta M. Yusof ◽  
M. Zarkashi Sulaiman ◽  
Rahimah A. Halim ◽  
Nurfaridah Ahmad Fauzi ◽  
Ahgheelan Sella Thurai ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Statistical Approach ◽  
Control Method ◽  
Low Cost ◽  
Volatile Oil ◽  
Field Application ◽  
Well Design ◽  
Execution Phase ◽  
Sand Control ◽  
Fit For Purpose

Abstract This paper discusses the Case study of Field A in offshore Sarawak, Malaysia which focus on re-thinking development based on statistical analysis of the fields. Conventionally, well design is driven by subsurface requirement by targeting the high-reserve sand and well is designed to meet subsurface objectives. However, the conventional way may not be efficient to develop matured field environment due to the high CAPEX and the inconsistencies among well design especially in current volatile oil price period. The objective of this fit-for-purpose approach which is called "Cone Concept Statistical Approach" is to steer away from the conventional way of targeting only sweet spots whilst leaving the remaining potential resources undeveloped. Based on the statistical analysis and subsurface fields pattern, the "Cone Concept Statistical Approach" in which standardizing well design and trajectories was developed to extract the whole fields’ reserve at maximum. Well design boundaries were introduced to ensure this approach can be replicated throughout the field. Not only this study covers drilling perspective, completion perspective was also taken into consideration by exploring a cheaper and fit for purpose sand control method, considering it is a matured field with relatively short remaining field life. The Well Cost Catalogue for this field-specific approach was also developed which contains different types of design and completion, in order to holistically evaluate sand control method and identify the best option for the project moving forward. This "Cone Concept Statistical Approach" aims to enable operator to drill simple wells within the same allocated budget in which poses low-to-no risk in the design and execution phase. This promotes a learning curve to improve operation & HSE, and ultimately gets positive project economics. Since this simple approach can be implemented early on even during the pre-FEL stage, the FDP team & host authority can come together to jointly discuss the targets/platform ranking and segregate them into various phases. Hence, the number of platforms or drilling centers, and its location also can be optimized early on with this concept, and again, translating into further reduction in overall project cost. This paper will help other operators and host authority to understand better on how a specific development concept on statistical approach can result and turn the matured-challenging fields into more economically attractive projects – low overall development cost and maximizing the recovery.

scholarly journals Nanoelectrode Arrays Fabricated by Thermal Nanoimprint Lithography for Biosensing Application

Biosensors ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 90
Author(s):  
Alessandra Zanut ◽  
Alessandro Cian ◽  
Nicola Cefarin ◽  
Alessandro Pozzato ◽  
Massimo Tormen
Keyword(s):  
Nanoimprint Lithography ◽  
Electrochemical Sensors ◽  
Low Cost ◽  
Scale Up ◽  
Electrochemical Sensing ◽  
Electrical Measurements ◽  
Boron Doped Diamond ◽  
Sensing Platform ◽  
Increased Sensitivity ◽  
Gliadin Protein

Electrochemical sensors are devices capable of detecting molecules and biomolecules in solutions and determining the concentration through direct electrical measurements. These systems can be miniaturized to a size less than 1 µm through the creation of small-size arrays of nanoelectrodes (NEA), offering advantages in terms of increased sensitivity and compactness. In this work, we present the fabrication of an electrochemical platform based on an array of nanoelectrodes (NEA) and its possible use for the detection of antigens of interest. NEAs were fabricated by forming arrays of nanoholes on a thin film of polycarbonate (PC) deposited on boron-doped diamond (BDD) macroelectrodes by thermal nanoimprint lithography (TNIL), which demonstrated to be a highly reliable and reproducible process. As proof of principle, gliadin protein fragments were physisorbed on the polycarbonate surface of NEAs and detected by immuno-indirect assay using a secondary antibody labelled with horseradish peroxidase (HRP). This method allows a successful detection of gliadin, in the range of concentration of 0.5–10 μg/mL, by cyclic voltammetry taking advantage from the properties of NEAs to strongly suppress the capacitive background signal. We demonstrate that the characteristics of the TNIL technology in the fabrication of high-resolution nanostructures together with their low-cost production, may allow to scale up the production of NEAs-based electrochemical sensing platform to monitor biochemical molecules for both food and biomedical applications.

scholarly journals 2D Materials in Development of Electrochemical Point-of-Care Cancer Screening Devices

Micromachines ◽  
2019 ◽  
Vol 10 (10) ◽  
pp. 662 ◽  
Author(s):  
Mohsen Mohammadniaei ◽  
Huynh Vu Nguyen ◽  
My Van Tieu ◽  
Min-Ho Lee
Keyword(s):  
Cancer Screening ◽  
2D Materials ◽  
Point Of Care ◽  
Low Cost ◽  
Clinical Analysis ◽  
Cancer Diagnostics ◽  
Electrochemical Sensing ◽  
Screening Tools ◽  
Electrochemical Biosensors ◽  
2D Material

Effective cancer treatment requires early detection and monitoring the development progress in a simple and affordable manner. Point-of care (POC) screening can provide a portable and inexpensive tool for the end-users to conveniently operate test and screen their health conditions without the necessity of special skills. Electrochemical methods hold great potential for clinical analysis of variety of chemicals and substances as well as cancer biomarkers due to their low cost, high sensitivity, multiplex detection ability, and miniaturization aptitude. Advances in two-dimensional (2D) material-based electrochemical biosensors/sensors are accelerating the performance of conventional devices toward more practical approaches. Here, recent trends in the development of 2D material-based electrochemical biosensors/sensors, as the next generation of POC cancer screening tools, are summarized. Three cancer biomarker categories, including proteins, nucleic acids, and some small molecules, will be considered. Various 2D materials will be introduced and their biomedical applications and electrochemical properties will be given. The role of 2D materials in improving the performance of electrochemical sensing mechanisms as well as the pros and cons of current sensors as the prospective devices for POC screening will be emphasized. Finally, the future scopes of implementing 2D materials in electrochemical POC cancer diagnostics for the clinical translation will be discussed.

Self-Sensing Composite Materials With Intelligent Fabrics

2019 ◽  
Author(s):  
Federico Fabriani ◽  
Giulia Lanzara
Keyword(s):  
Composite Materials ◽  
Structural Health Monitoring ◽  
Glass Fiber ◽  
Health Monitoring ◽  
Chemical Resistance ◽  
Piezoelectric Properties ◽  
Low Cost ◽  
High Chemical ◽  
Monitoring Applications ◽  
High Chemical Resistance

Abstract The excellent piezoelectric properties of Polyvinyl Fluoride (PVDF), its low cost, ease of workability and high chemical resistance, make it very useful to develop sensing devices for structural health monitoring applications (SHM). However, challenges occur when the devices need to be embedded into a hosting material or structure which could instead be damaged. In this study, the PVDF device is transformed into an ultralight and porous piezoelectric mat formed by ultra-long and randomly distributed micro fibers. The piezoelectric mat is embedded into a glass fiber (GF) composite by intercalating it with the GF layers during the lay-up process. This approach allows the realization of an intelligent composite that is capable to self-monitor its strain or vibrations during inservice life.

Low Cost Paper Based Electrochemical Sensing System

2019 ◽  
Author(s):  
Ava Hedayatipour ◽  
Shahram Hatefi Hesari ◽  
Shaghayegh Aslanzadeh ◽  
Varsha Mohan ◽  
Rania Oueslati ◽  
...  
Keyword(s):  
Low Cost ◽  
Electrochemical Sensing ◽  
Sensing System
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