scholarly journals Advances in Antibacterial Functionalized Coatings on Mg and Its Alloys for Medical Use—A Review

Coatings ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 828
Author(s):  
Dan Zhang ◽  
Ying Liu ◽  
Zhaogang Liu ◽  
Qiang Wang
Keyword(s):  
Corrosion Resistance ◽  
Degradation Rate ◽  
Composite Coatings ◽  
Alkaline Ph ◽  
Antibacterial Ability ◽  
Infected Wounds ◽  
Patients With Diabetes ◽  
Biological Environment ◽  
Functionalized Coatings

As a revolutionary implant material, magnesium and its alloys have many exciting performances, such as biodegradability, mechanical compatibility, and excellent biosecurity. However, the rapid and uncontrollable degradation rate of magnesium greatly hampers its clinical use. Many efforts have been taken to enhance the corrosion resistance of magnesium. However, it must be noted that improving the corrosion resistance of magnesium will lead to the compromise of its antibacterial abilities, which are attribute and proportional to the alkaline pH during its degradation. Providing antibacterial functionalized coating is one of the best methods for balancing the degradation rate and the antibacterial ability of magnesium. Antibacterial functionalized magnesium is especially well-suited for patients with diabetes and infected wounds. Considering the extremely complex biological environment in the human body and the demands of enhancing corrosion resistance, biocompatibility, osteogenesis, and antibacterial ability, composite coatings with combined properties of different materials may be promising. The aim of this review isto collect and compare recent studies on antibacterial functionalized coatings on magnesium and its alloys. The clinical applications of antibacterial functionalized coatings and their material characteristics, antibacterial abilities, in vitro cytocompatibility, and corrosion resistance are also discussed in detail.

In Vitro Evaluation of Degradation of Biodegradable Silane Based Coating on Mg-Zn-Ca Alloy in a Physiological Environment

2013 ◽  
Vol 765 ◽  
pp. 803-807
Author(s):  
Gaur Swati ◽  
Anand Sawroop Khanna ◽  
Raghuvir Kumar Singh Raman
Keyword(s):  
Corrosion Resistance ◽  
Electrochemical Impedance Spectroscopy ◽  
Magnesium Alloy ◽  
Impedance Spectroscopy ◽  
Body Fluid ◽  
Degradation Rate ◽  
Electrochemical Impedance ◽  
Silane Coating ◽  
Corrosion Barrier

In the present study, combinations of a phosphonato silane with a precursor, Methyltriethoxy silane (MTEOS) in various ratios were applied onto the alloy Mg-6Zn-Ca. The corrosion resistance of the coated and uncoated specimens in a modified simulated body fluid (m-SBF) was characterized by potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). Results suggest that the silane coating significantly decreases the degradation rate of the magnesium alloy, indicating its potential to be used as a corrosion barrier for magnesium alloy temporary implants.

scholarly journals Effect of solid-solution and aging treatment on corrosion behavior of orthogonal designed and vacuum melted Mg-Zn-Ca-Mn alloys

2020 ◽  
Vol 18 ◽  
pp. 228080001988790 ◽  
Author(s):  
Dexue Liu ◽  
Tianshui Zhou ◽  
Zehua Liu ◽  
Bing Guo
Keyword(s):  
Solid Solution ◽  
Corrosion Resistance ◽  
Degradation Rate ◽  
Cast Alloy ◽  
Vacuum Induction Melting ◽  
Corrosion Properties ◽  
X Ray ◽  
Orthogonal Method ◽  
Heat Treated

Fast degradation rate and inhomogeneous corrosion are obstacles for magnesium alloy bio-corrosion properties. In this paper, a quaternary Mg-Zn-Ca-Mn alloy was designed by an orthogonal method and prepared by vacuum induction melting to investigate its bio-corrosion. Microstructure, corrosion morphology, and bio-corrosion properties of as-cast alloys 1 to 5 with good corrosion resistance were characterized by scanning electron microscopy, energy dispersive X-ray spectroscopy, and X-ray diffraction with immersion and electrochemical tests in simulated body fluid (SBF), respectively. Both the orthogonal method and in vitro degradation experiments demonstrated that alloy 3 exhibited the lowest degradation rate among the tested quaternary Mg-Zn-Ca-Mn alloys. Then, as-cast alloy 3 was treated by solid-solution and solid-solution aging. In vitro experimental results indicated that as-cast alloy 3 showed better corrosion resistance than heat-treated specimens and the average corrosion rate was approximately 0.15 mm/y. Heat-treated alloy 3 exhibited more uniform corrosion than as-cast alloy specimens. These results suggest that alloy 3 has the potential to become a biodegradable candidate material.

Mg alloy surface immobilised with caerin peptides acquires enhanced antibacterial ability and improved corrosion resistance

2020 ◽  
Author(s):  
Tianfang Wang ◽  
Guoying Ni ◽  
Tsuyoshi Furushima ◽  
Hui Diao ◽  
Pingping Zhang ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Antibacterial Effect ◽  
Click Reaction ◽  
Mg Alloys ◽  
Mg Alloy ◽  
Alloy Sample ◽  
Plasma Chemical ◽  
Antibacterial Ability ◽  
Comparison Results

Abstract Magnesium (Mg) has mechanical properties similar to human bones and Mg alloy is considered ideal medical implant material. However, the high velocity of degradation inside the human inner environment severely hampers the usage of Mg alloys. In this study, caerin peptide 1.9 (F3) and a modified sequence of caerin 1.1 (F1) with anti-bacterial activity, were covalently immobilised on the surface of Mg alloys by plasma chemical click reaction. The in vitro antibacterial activity and corrosion resistance of these caerin peptide-immobilised Mg alloys were investigated in Dulbecco's Modified Eagle Medium (DMEM) solution. Un-immobilised Mg alloy sample, blank drug-sensitive tablet (BASD) and a commonly used antibiotics Tazocin were used for comparison. Results showed that peptide immobilised Mg samples showed significant improved corrosion resistance and prolonged antibacterial effect compared to non-immobilised Mg alloy and free caerin peptides. Furthermore, annealing or extruding treatment of Mg alloys improved the behaviours of corrosion resistance and antibacterial property. These results indicate that coating Mg alloy with caerin peptides improves the corrosion resistance in vitro and increases the alloy’s antibacterial ability. The mechanism underlying the prolonged antibacterial effect for annealed Mg alloys immobilised with the peptides (especially F3) remains unclear, which worth further experimental and theoretical investigation.

Studies and Research on the Corrosion Behavior of Ni-Al2O3 Compound Coatings Obtained by Electrochemical Methods

2020 ◽  
Vol 43 (3) ◽  
pp. 21-25
Author(s):  
Simona BOICIUC ◽  
◽  
◽  
Keyword(s):  
Corrosion Resistance ◽  
Corrosion Behavior ◽  
Corrosion Behaviour ◽  
Composite Coatings ◽  
Point Of View ◽  
Electrochemical Methods ◽  
Dispersed Phase ◽  
Nickel Matrix ◽  
Technical Alumina ◽  
Compound Coatings

The undertaken research which is described in this paper aims at the corrosion behaviour of composite coatings in nickel matrix using as dispersed phase technical alumina with dimensions of 5 μm and their characterization from a microstructural point of view. The corrosion resistance in the saline fog of the coatings is influenced by the microstructure, the stresses developed in the layer and the roughness.

scholarly journals Fabrication and Characterization of Antimicrobial Magnetron Cosputtered TiO2/Ag/Cu Composite Coatings

Coatings ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 473
Author(s):  
Dilyana Gospodonova ◽  
Iliana Ivanova ◽  
Todorka Vladkova
Keyword(s):  
Antimicrobial Activity ◽  
Composite Coatings ◽  
Surface Characteristics ◽  
Standard Test ◽  
Most Probable Number ◽  
Bacterial Strains ◽  
Probable Number ◽  
Fabrication And Characterization

The aim of this study was to prepare TiO2/Ag/Cu magnetron co-sputtered coatings with controlled characteristics and to correlate them with the antimicrobial activity of the coated glass samples. The elemental composition and distribution, surface morphology, wettability, surface energy and its component were estimated as the surface characteristics influencing the bioadhesion. Well expressed, specific, Ag/Cu concentration-dependent antimicrobial activity in vitro was demonstrated toward Gram-negative and Gram-positive standard test bacterial strains both by diffusion 21 assay and by Most Probable Number of surviving cells. Direct contact and eluted silver/coper nanoparticles killing were experimentally demonstrated as a mode of the antimicrobial action of the studied TiO2/Ag/Cu thin composite coatings. It is expected that they would ensure a broad spectrum bactericidal activity during the indwelling of the coated medical devices and for at least 12 h after that, with the supposition that the benefits will be over a longer time.

scholarly journals Zn-Co-CeO2 vs. Zn-Co Coatings: Effect of CeO2 Sol in the Enhancement of the Corrosion Performance of Electrodeposited Composite Coatings

Metals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 704
Author(s):  
Marija Riđošić ◽  
Nebojša D. Nikolić ◽  
Asier Salicio-Paz ◽  
Eva García-Lecina ◽  
Ljiljana S. Živković ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Healing Rate ◽  
Electrochemical Impedance ◽  
Composite Coatings ◽  
Self Healing ◽  
Kelvin Probe ◽  
Artificial Defect ◽  
Volta Potential ◽  
Superior Corrosion Resistance ◽  
The Stability

Electrodeposition and characterization of novel ceria-doped Zn-Co composite coatings was the main goal of this research. Electrodeposited composite coatings were compared to pure Zn-Co coatings obtained under the same conditions. The effect of two ceria sources, powder and home-made sol, on the morphology and corrosion resistance of the composite coatings was determined. During the electrodeposition process the plating solution was successfully agitated in an ultrasound bath. The source of the particles was found to influence the stability and dispersity of plating solutions. The application of ceria sol resulted in an increase of the ceria content in the resulting coating and favored the refinement from cauliflower-like morphology (Zn-Co) to uniform and compact coral-like structure (Zn-Co-CeO2 sol). The corrosion resistance of the composite coatings was enhanced compared to bare Zn-Co as evidenced by electrochemical impedance spectroscopy and scanning Kelvin probe results. Zn-Co doped with ceria particles originating from ceria sol exhibited superior corrosion resistance compared to Zn-Co-CeO2 (powder) coatings. The self-healing rate of artificial defect was calculated based on measured Volta potential difference for which Zn-Co-CeO2 (sol) coatings exhibited a self-healing rate of 73.28% in a chloride-rich environment.

scholarly journals Mechanical Properties, Corrosion Resistance and Bioactivity of Oxide Layers Formed by Isothermal Oxidation of Ti-6Al-7Nb Alloy

Coatings ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 505
Author(s):  
Krzysztof Aniołek ◽  
Bożena Łosiewicz ◽  
Julian Kubisztal ◽  
Patrycja Osak ◽  
Agnieszka Stróż ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Corrosion Resistance ◽  
Contact Potential Difference ◽  
Isothermal Oxidation ◽  
Potential Method ◽  
Open Circuit ◽  
Kelvin Probe ◽  
Contact Potential ◽  
Oxide Layers

Titanium and its alloys are among the most promising biomaterials for medical applications. In this work, the isothermal oxidation of Ti-6Al-7Nb biomedical alloy towards improving its mechanical properties, corrosion resistance, and bioactivity has been developed. The oxide layers were formed at 600, 700, and 800 °C for 72 h. Scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), 3D profilometry, and microindentation test, were used to characterize microstructure, surface geometrical structure, and the hardness of the diphase (α + β) Ti-6Al-7Nb alloy after oxidation, respectively. In vitro corrosion resistance tests were carried out in a saline solution at 37 °C using the open-circuit potential method and potentiodynamic measurements. Electronic properties in the air were studied using the Scanning Kelvin Probe (SKP) technique. The bioactivity test was conducted by soaking the alkali- and heat-treated samples in simulated body fluid for 7 days. The presence of apatite was confirmed using SEM/EDS and Fourier Transform Infrared Spectroscopy (FTIR) studies. The thickness of oxide layers formed increased with the temperature growth from 0.25 to 5.48 µm. It was found that with increasing isothermal oxidation temperature, the surface roughness, hardness, corrosion resistance, and contact potential difference increased. The Ti-6Al-7Nb alloy after oxidation revealed the HAp-forming ability in a biological environment.

scholarly journals Preparation and Degradation Characteristics of MAO/APS Composite Bio-Coating in Simulated Body Fluid

Coatings ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 667
Author(s):  
Zexin Wang ◽  
Fei Ye ◽  
Liangyu Chen ◽  
Weigang Lv ◽  
Zhengyi Zhang ◽  
...  
Keyword(s):  
Simulated Body Fluid ◽  
Composite Coating ◽  
Body Fluid ◽  
Composite Coatings ◽  
Degradation Process ◽  
Ceramic Coatings ◽  
Immersion Test ◽  
Substrate Material ◽  
Atmospheric Plasma

In this work, ZK60 magnesium alloy was employed as a substrate material to produce ceramic coatings, containing Ca and P, by micro-arc oxidation (MAO). Atmospheric plasma spraying (APS) was used to prepare the hydroxyapatite layer (HA) on the MAO coating to obtain a composite coating for better biological activity. The coatings were examined by various means including an X-ray diffractometer, a scanning electron microscope and an energy spectrometer. Meanwhile, an electrochemical examination, immersion test and tensile test were used to evaluate the in vitro performance of the composite coatings. The results showed that the composite coating has a better corrosion resistance. In addition, this work proposed a degradation model of the composite coating in the simulated body fluid immersion test. This model explains the degradation process of the MAO/APS coating in SBF.

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