scholarly journals Epigenetic Analyses of Alcohol Consumption in Combustible and Non-Combustible Nicotine Product Users

Epigenomes ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 18
Author(s):  
Kelsey Dawes ◽  
Luke Sampson ◽  
Rachel Reimer ◽  
Shelly Miller ◽  
Robert Philibert ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Self Report ◽  
Classification Model ◽  
Public And Private ◽  
Random Forest Classification ◽  
Epigenetic Biomarkers ◽  
Forest Classification ◽  
Heavy Alcohol Consumption ◽  
Relationship Of ◽  
The Relationship

Alcohol and tobacco use are highly comorbid and exacerbate the associated morbidity and mortality of either substance alone. However, the relationship of alcohol consumption to the various forms of nicotine-containing products is not well understood. To improve this understanding, we examined the relationship of alcohol consumption to nicotine product use using self-report, cotinine, and two epigenetic biomarkers specific for smoking (cg05575921) and drinking (Alcohol T Scores (ATS)) in n = 424 subjects. Cigarette users had significantly higher ATS values than the other groups (p < 2.2 × 10−16). Using the objective biomarkers, the intensity of nicotine and alcohol consumption was correlated in both the cigarette and smokeless users (R = −0.66, p = 3.1 × 10−14; R2 = 0.61, p = 1.97 × 10−4). Building upon this idea, we used the objective nicotine biomarkers and age to build and test a Balanced Random Forest classification model for heavy alcohol consumption (ATS > 2.35). The model performed well with an AUC of 0.962, 89.3% sensitivity, and 85% specificity. We conclude that those who use non-combustible nicotine products drink significantly less than smokers, and cigarette and smokeless users drink more with heavier nicotine use. These findings further highlight the lack of informativeness of self-reported alcohol consumption and suggest given the public and private health burden of alcoholism, further research into whether using non-combustible nicotine products as a mode of treatment for dual users should be considered.

Administrasi Hubungan Sekolah dan Masyarakat (HUSEMAS)

2020 ◽  
Author(s):  
Rifa Nirmala ◽  
Hade Afriansyah
Keyword(s):  
Personal Growth ◽  
Clear Picture ◽  
Public And Private ◽  
Community Needs ◽  
The People ◽  
Good Will ◽  
Relationship Of ◽  
The Relationship

Thus can drawing conclusions about the relationship of the school with the community is essentially a very decisive tool in fostering and developing the personal growth of students in schools. If the relationship between the school and the community goes well, the sense of responsibility and participation of the community to advance the school will also be good and high. In order to create relationships and cooperation between schools and the community, the community needs to know and have a clear picture of the school they have obtained.The presence of schools is based on the good will of the country and the people who support it. Therefore people who work in schools inevitably have to work with the community. The community here can be in the form of parents of students, agencies, organizations, both public and private. One reason schools need help from the community where schools are because schools must be funded.

scholarly journals The relationship of insight with psychopathological dimensions in patients with schizophrenia

2021 ◽  
Vol 12 (2) ◽  
pp. 204380872110199
Author(s):  
Si-Sheng Huang ◽  
Cheng-Chen Chang
Keyword(s):  
Medical Center ◽  
Self Report ◽  
Psychiatric Ward ◽  
Neurocognitive Functions ◽  
Bivariate Correlation ◽  
Syndrome Scale ◽  
Acute Psychiatric Ward ◽  
Negative Syndrome ◽  
Relationship Of ◽  
The Relationship

Impaired insight in patients with schizophrenia results in less satisfactory clinical outcomes. This study was conducted to investigate the relationship between insight and individual psychopathological dimensions in inpatients with schizophrenia using a self-report questionnaire. In this study, 90 patients with schizophrenia aged 18–75 years admitted in the acute psychiatric ward of a medical center in Taiwan were enrolled. Patient insight was measured using the Self-Appraisal of Illness Questionnaire (SAIQ), and psychopathological dimensions were measured using the Positive and Negative Syndrome Scale (PANSS) and its five-factor structure model. A higher SAIQ score indicates greater insight. In bivariate correlation analyses, statistically significant correlations were observed between age, single marital status, educational level, and positive, excited, and depressed symptom factor of the PANSS and SAIQ score. In regression analyses, age and excited and depressed symptom factors were significantly associated with SAIQ score. No significant association was observed between insight and neurocognitive functions. Considering demographic characteristics, psychopathology, and neurocognition, in the acute phase of schizophrenia, younger patients with less severe excited symptoms and more severe depressive symptoms had greater insight.

The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: an overview

Addiction ◽  
2003 ◽  
Vol 98 (9) ◽  
pp. 1209-1228 ◽  
Author(s):  
Jürgen Rehm ◽  
Robin Room ◽  
Kathryn Graham ◽  
Maristela Monteiro ◽  
Gerhard Gmel ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Burden Of Disease ◽  
Average Volume ◽  
Patterns Of Drinking ◽  
Relationship Of ◽  
The Relationship

The relationship of self-report and behavioral assertion in an offender population

1979 ◽  
Vol 10 (4) ◽  
pp. 283-286 ◽  
Author(s):  
Richard G. Heimberg ◽  
Dianne F. Harrison ◽  
Lewis S. Goldberg ◽  
Steven Desmarais ◽  
Susan Blue
Keyword(s):  
Self Report ◽  
Relationship Of ◽  
The Relationship

scholarly journals Relationship between the intention–behavior gap and self-efficacy for physical activity during childhood

2018 ◽  
Vol 23 (1) ◽  
pp. 79-86 ◽  
Author(s):  
Tsunenori Isa ◽  
Yuya Ueda ◽  
Ryo Nakamura ◽  
Shogo Misu ◽  
Rei Ono
Keyword(s):  
Physical Activity ◽  
High Activity ◽  
Self Efficacy ◽  
Self Report ◽  
Physically Active ◽  
Education Interventions ◽  
Relationship Of ◽  
The Relationship ◽  
Low Activity ◽  
Actual Participation

This study investigated the relationship of a gap between the intent to be physically active and actual participation in physical activity (‘intention–behavior gap’) and self-efficacy for physical activity during childhood. A self-report questionnaire was used to collect information from 946 children from the fourth and sixth grades in Japan on self-efficacy, intention, and physical activity. Children with an intention–behavior gap (high intent–low activity or low intent–high activity) had higher self-efficacy scores than those with low intent and low activity (27.66 or 27.65 vs. 21.69; p < .001). They had lower self-efficacy scores than those with high intent and high activity (27.66 or 27.65 vs. 30.56; p < .001). Children with an intention–behavior gap had lower self-efficacy for physical activity than those who intended to be and were physically active. Such children may benefit from education interventions that focus on improving self-efficacy.

scholarly journals Dynamics of the relationship of emotional intelligence with the results of the state exam during the adaptation of school system to its introduction

2015 ◽  
Vol 8 (2) ◽  
pp. 139-150
Author(s):  
E.S. Dmitrieva ◽  
V.Ya. Gelman
Keyword(s):  
Emotional Intelligence ◽  
School System ◽  
The State ◽  
Russian Language ◽  
Self Report ◽  
First Year ◽  
First Year Students ◽  
Adaptation Processes ◽  
Relationship Of ◽  
The Relationship

Research is devoted to the study of the relationship of emotional intelligence of students with the results of the state exam in the adaptation of the school system for 5 years from the date of introduction. The sample consisted of 156 first-year students. Evaluation of the components of emotional intelligence was measured by self-report (EmIn questionnaire). There was a statistically significant correlation between the severity of different indicators of emotional intelligence of students passing the exam and the results of the three school subjects: Russian language, Mathematics, Social studies. It is shown that since the introduction in 2009 of compulsory exam the level of communication between the indicators of emotional intelligence and the results of the examination has changed. Adaptation processes to the introduction of the state exam lead to changes contingent of successful students: If at the time of the introduction of the exam more successful were students with higher EI, in the process of adaptation more successful became those with lower EI. It was shown that the components of EI, having the most important relationships with the results of the exam, are different for the considered subjects; the dynamics of these relationships has been revealed.

scholarly journals Fully Automated Detection of Paramagnetic Rims in Multiple Sclerosis Lesions on 3T Susceptibility-Based MR Imaging

2020 ◽  
Author(s):  
Carolyn Lou ◽  
Pascal Sati ◽  
Martina Absinta ◽  
Kelly Clark ◽  
Jordan D. Dworkin ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Severe Disease ◽  
Area Under The Curve ◽  
Machine Learning Algorithms ◽  
Classification Model ◽  
List Type ◽  
Training Set ◽  
Random Forest Classification ◽  
Automated Method ◽  
Forest Classification

AbstractBackground and PurposeThe presence of a paramagnetic rim around a white matter lesion has recently been shown to be a hallmark of a particular pathological type of multiple sclerosis (MS) lesion. Increased prevalence of these paramagnetic rim lesions (PRLs) is associated with a more severe disease course in MS. The identification of these lesions is time-consuming to perform manually. We present a method to automatically detect PRLs on 3T T2*-phase images.MethodsT1-weighted, T2-FLAIR, and T2*-phase MRI of the brain were collected at 3T for 19 subjects with MS. The images were then processed with lesion segmentation, lesion center detection, lesion labelling, and lesion-level radiomic feature extraction. A total of 877 lesions were identified, 118 (13%) of which contained a paramagnetic rim. We divided our data into a training set (15 patients, 673 lesions) and a testing set (4 patients, 204 lesions). We fit a random forest classification model on the training set and assessed our ability to classify lesions as PRL on the test set.ResultsThe number of PRLs per subject identified via our automated lesion labelling method was highly correlated with the gold standard count of PRLs per subject, r = 0.91 (95% CI [0.79, 0.97]). The classification algorithm using radiomic features can classify a lesion as PRL or not with an area under the curve of 0.80 (95% CI [0.67, 0.86]).ConclusionThis study develops a fully automated technique for the detection of paramagnetic rim lesions using standard T1 and FLAIR sequences and a T2*phase sequence obtained on 3T MR images.HighlightsA fully automated method for both the identification and classification of paramagnetic rim lesions is proposed.Radiomic features in conjunction with machine learning algorithms can accurately classify paramagnetic rim lesions.Challenges for classification are largely driven by heterogeneity between lesions, including equivocal rim signatures and lesion location.

scholarly journals Drunkorexia: empirical investigation and analysis of the characteristics of the phenomenon in an Italian sample of adolescents and young adults

2018 ◽  
Vol 10 (3) ◽  
pp. 285 ◽  
Author(s):  
Giada Pietrabissa ◽  
Alessandro Rossi ◽  
Michela Gaudenzi ◽  
Venessa Bertuzzi ◽  
Andrea Tagliagambe ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Disordered Eating ◽  
Weight Control ◽  
Ad Hoc ◽  
Eating Habits ◽  
Univariate Analysis ◽  
Self Report ◽  
Drinking Problems ◽  
The Relationship ◽  
Italian Sample

Introduction: the term drunkorexia refers to the act of self-imposed utilization of extreme weight control methods to compensate for alcohol consumption typically observed among university students. Despite its diffusion, there is a lack of research investigating the presence of this new alarming trend in Italy. Aim: this study estimates the frequency of drunkorexia behaviours in a sample of Italian youth aged 14-24, explores the motivations for alcohol consumption among those presenting drunkorexia-type behaviours, and examines the relationship between drunkorexia and disordered eating. Methods: drunkorexia behaviors, eating habits and motives for alcohol use were investigated in 403 subjects (F=301, M=102) aged 14-24 through self-report questionnaires. A series of analyses, including descriptive statistics, univariate analysis of the variance and multiple regressions were run. Results: 62.5% of the sample showed drunkorexia-type behaviours. Drunkorexia was related to disordered eating, especially among females older than eighteen. Discussion and Conclusions: this the first study investigating the incidence of drunkorexia behaviors in a sample of youth living in Northern Italy. Evidence-based interventions for eating disorders and drinking problems should inspire the development of ad hoc preventive and treatment actions for drunkorexia. 

Relationship of Manifest Aggressiveness to Aggressive Word Associations

1969 ◽  
Vol 25 (3) ◽  
pp. 711-714 ◽  
Author(s):  
Russell G. Geen ◽  
Robert George
Keyword(s):  
Verbal Behavior ◽  
Social Desirability ◽  
Habit Strength ◽  
Self Report ◽  
Social Desirability Scale ◽  
Word Associations ◽  
Highly Correlated ◽  
Cue Words ◽  
Relationship Of ◽  
The Relationship

A self-report inventory made up of items from the Buss-Durkee manifest aggressiveness scales, the Marlowe-Crowne Social Desirability Scale, and the Masculinity-Femininity scale of the Guilford-Zimmerman Temperament Survey was administered to 72 men along with a test of verbal associations to aggressive and neutral cue words. The number of aggressive associations made to aggressive cue words was highly correlated with over-all manifest aggressiveness and with two of the aggressiveness subscales. The results were discussed in terms of the relationship of aggressiveness habit strength to verbal behavior.

The changing landscape of local authority commissioning

2020 ◽  
pp. 177-196
Author(s):  
Dave Ayre
Keyword(s):  
Academic Research ◽  
The European Union ◽  
Public And Private ◽  
The United Kingdom ◽  
Health And Social Care ◽  
History Of ◽  
The Uk ◽  
Relationship Of ◽  
The Relationship

This chapter assesses the history of the relationship between public and private sectors and the extent to which the political and regulatory environment of governments and institutions such as the European Union (EU) can help or hinder the efforts of public bodies in seeking to deliver services that determine the health and quality of life for communities. The relationship of public and private sectors in the United Kingdom (UK) and the commissioning, procurement, and development of public–private partnerships is driven by the prevailing political and economic environment. However, rigorous academic research on the benefits of partnering to organisations, societies and between countries is limited. Evidence is needed to fill the policy vacuum. A bolder approach is necessary to work with public and private sectors to develop and implement successful partnering alternatives to the outsourcing of public services. The growing catalogue of outsourcing failures in construction, probation, rail franchising, health, and social care is creating an appetite for change, and the exit of the UK from the EU provides the opportunity.

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