scholarly journals Bibliometric Analysis of Chronic Traumatic Encephalopathy Research from 1999 to 2019

Author(s):  
Bote Qi ◽  
Shuting Jin ◽  
Hongsheng Qian ◽  
Yu Zou

Research on chronic traumatic encephalopathy (CTE) has increased over the past two decades. However, few studies have statistically analyzed these publications. In this work, we conducted a bibliometric analysis of studies on CTE to track research trends and highlight current research hotspots. Relevant original articles were obtained from the Web of Science Core Collection database between 1999 and 2019. CiteSpace and VOSviewer software were used to perform analysis and visualization of scientific productivity and emerging trends. Our results show that the publications related to CTE dramatically increased from four publications in 1999 to 160 publications in 2019. The United States dominated this field with 732 publications (75.934%), followed by Canada with 88 publications (9.129%). Most of related publications were published in the journals with a focus on molecular biology, immunology, neurology, sports and ophthalmology, as represented by the dual-map overlay. A total of 11 major clusters were explored based on the reference co-citation analysis. In addition, three predominant research topics were summarized by clustering high-frequency keywords: epidemiological, clinical and pathological studies. The research frontiers were the diagnosis of diseases using new neuroimaging techniques, and the investigation of the molecular mechanism of tau aggregation. This study provides researchers with valuable guidance in the selection of research topics.

2021 ◽  
Author(s):  
Qiaochu Wei ◽  
Jiming Shen ◽  
Dongni Wang ◽  
Xu Han ◽  
Jing Shi ◽  
...  

Abstract Background: Flap endonuclease 1 (FEN1) is a structure-specific nuclease that plays a role in a variety of DNA metabolism processes. FEN1 is important for maintaining genomic stability and regulating cell growth and development. It is associated with the occurrence and development of several diseases, especially cancers. There is a lack of systematic bibliometric analyses focusing on research trends and knowledge structures related to FEN1.Purpose: To analyze hotspots, the current state and research frontiers performed for FEN1 over the past 15 years. Methods: Publications were retrieved from the Web of Science Core Collection (WoSCC) database, analyzing publication dates ranging from 2005 to 2019. VOSviewer1.6.15 and Citespace5.7 R1 were used to perform a bibliometric analysis in terms of countries, institutions, authors, journals and research areas related to FEN1. A total of 421 publications were included in this analysis. Results: Our findings indicated that FEN1 has received more attention and interest from researchers in the past 15 years. Institutes in the United States, specifically the Beckman Research Institute of City of Hope published the most research related to FEN1. SHEN BH,ZHENG L and BAMBARA RA were the most active researchers investigating this endonuclease and most of this research was published in the Journal of Biological Chemistry. The main scientific areas of FEN1 were related to biochemistry, molecular biology,cell biology,genetics and oncology. Research hotspots included biological activities, DNA metabolism mechanisms, protein-protein interactions and gene mutations. Research frontiers included oxidative stress, phosphorylation and tumor progression and treatment. Conclusion: This bibliometric study may aid researchers in the understanding of the knowledge base and research frontiers associated with FEN1. In addition, emerging hotspots for research can be used as the subjects of future studies.


BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qiaochu Wei ◽  
Jiming Shen ◽  
Dongni Wang ◽  
Xu Han ◽  
Jing Shi ◽  
...  

Abstract Background Flap endonuclease 1 (FEN1) is a structure-specific nuclease that plays a role in a variety of DNA metabolism processes. FEN1 is important for maintaining genomic stability and regulating cell growth and development. It is associated with the occurrence and development of several diseases, especially cancers. There is a lack of systematic bibliometric analyses focusing on research trends and knowledge structures related to FEN1. Purpose To analyze hotspots, the current state and research frontiers performed for FEN1 over the past 15 years. Methods Publications were retrieved from the Web of Science Core Collection (WoSCC) database, analyzing publication dates ranging from 2005 to 2019. VOSviewer1.6.15 and Citespace5.7 R1 were used to perform a bibliometric analysis in terms of countries, institutions, authors, journals and research areas related to FEN1. A total of 421 publications were included in this analysis. Results Our findings indicated that FEN1 has received more attention and interest from researchers in the past 15 years. Institutes in the United States, specifically the Beckman Research Institute of City of Hope published the most research related to FEN1. Shen BH, Zheng L and Bambara Ra were the most active researchers investigating this endonuclease and most of this research was published in the Journal of Biological Chemistry. The main scientific areas of FEN1 were related to biochemistry, molecular biology, cell biology, genetics and oncology. Research hotspots included biological activities, DNA metabolism mechanisms, protein-protein interactions and gene mutations. Research frontiers included oxidative stress, phosphorylation and tumor progression and treatment. Conclusion This bibliometric study may aid researchers in the understanding of the knowledge base and research frontiers associated with FEN1. In addition, emerging hotspots for research can be used as the subjects of future studies.


2020 ◽  
Author(s):  
Cheng-Cheng Wu ◽  
Hao-Yu Hu ◽  
Xue-Qiang Wang

Abstract Background: Pain is commonly associated with psychological variables, such as anxiety and depression. However, only a few studies statistically analyzed the global trends and conducted a review through the bibliometric method. Purpose: This work aimed to analyze the general aspects of scientific studies worldwide on the comorbid of anxiety and pain research between 2000 and 2019. Methods: Published papers on the comorbid of anxiety and pain from the last 2 decades were retrieved from the Web of Science core collection. To assess whether the percentage statistically decreased or increased over time by using IBM SPSS Statistics 22.0. Results: A total of 1,329 papers met the inclusion criteria. The trend of annual publications presented a significant growth from 2000 to 2019 (P<0.001) by linear regression analysis. Clinical Neurology, Neurosciences, and Anesthesiology of subject categories had superior quality and were recognized as mainstream on comorbid anxiety and pain research. The United States (416, 30.85%) and the University of Washington (23, 1.73%) were the most prolific and high-quality country and institution, respectively. Postoperative pain (11.81%) and headache (11.14%) were the hottest topic among researchers. Music, distraction, adult, dental anxiety, and preoperative anxiety were emerging hotspots and could be regarded as research frontiers. Conclusions: Bibliometric analysis of the comorbidity of anxiety and pain and provides insights into research countries, institutions, authors, and core journal, visual, hot topics, overall tendency, and research frontiers that will aid in exploring hidden valuable field for future research.


PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7115 ◽  
Author(s):  
Minglu Wang ◽  
Weitao Li ◽  
Yuying Tao ◽  
Limei Zhao

Background Epilepsy during pregnancy presents a unique set of challenges for pregnant women, the fetus, and the health care community. As research in this area advances rapidly, it is critical to keep up with the emerging trends and key turning points of the development of the domain knowledge. This study aimed to construct a series of science maps to quantitatively and qualitatively evaluate the intellectual landscape and research frontiers in the field of epilepsy during pregnancy research. Methods All publications were extracted from the Web of Science Core Collection database. Bibliometric analysis was used to analyze the scientific research outputs, including journals, countries/regions, institutions, authors (cited authors), intellectual base and research hotspots. Results A total of 2,225 publications related to epilepsy during pregnancy were identified as published between 2000 and 2018. The overall trend of the number of publications showed a fluctuating growth from 59 articles in 2000 to 198 in 2018. Neurology was the leading journal in the field of epilepsy and pregnancy research both in terms of impact factor score (8.055) and H-index value (77). The US retained its leading position and exerted a pivotal influence in this area. The University of Melbourne was identified as a good research institution for research collaboration. Prof. Pennell and Tomson have made great achievements in this area, and Prof. Tomson laid a foundation for the development of this domain. The keyword “neonatal seizures” ranked first in research hotspots, and the keyword “autism spectrum disorders (ASD)” ranked first in research frontiers. Conclusions Epilepsy during pregnancy is a fascinating and rapid development of subject matter. A more recent emerging trend focused on comprehensive management of pregnant and lactating women, evaluation of the safety and efficacy of newer antiepileptic drugs. The keywords “management issue,” “brain injury,” “meta-analysis,” “in utero exposure,” and “ASD” were the latest research frontiers and should be closely observed.


Author(s):  
Wang ◽  
Xia ◽  
Li ◽  
Wang

With the characteristics of low cost and open call, crowdsourcing has been widely adopted in many fields, particularly to support the use of surveys, data processing, and the monitoring of public health. The objective of the current study is to analyze the applications, hotspots, and emerging trends of crowdsourcing in the field of public health. Using CiteSpace for the visualization of scientific maps, this study explores the analysis of time-scope, countries and institutions, authors, published journals, keywords, co-references, and citation clusters. The results show that the United States is the country with the most publications regarding crowdsourcing applications for public health. Howe and Brabham are the two leading authors in this field. Further, most of the articles published in this field are found in medical and comprehensive journals. Crowdsourcing in public health is increasing and diversifying. The results of this study will enable and support the analysis of the specific role of crowdsourcing in the public health ecosystem.


2021 ◽  
Vol 12 ◽  
Author(s):  
Yan Zhou ◽  
Xue-Ping Zhu ◽  
Jing-Jing Shi ◽  
Guo-Zhen Yuan ◽  
Zi-Ang Yao ◽  
...  

This study aimed to conduct a bibliometric analysis of published studies on the association between coronary heart disease (CHD) and depression or anxiety. The study also aimed to identify leading authors, institutions, and countries to determine research hotspots and obtain some hints from the speculated future frontiers. Publications about CHD and depression or anxiety between 2004 and 2020 were collected from the Web of Science Core Collection (WOSCC) database. Bibliographic information, such as authorship, country, citation frequency, and interactive visualization, was generated using VOSviewer1.6.16 and CiteSpace5.6.R5. In total, 8,073 articles were identified in the WOSCC database. The United States (2,953 publications), Duke University and Harvard University (214 publications), Psychosomatic Medicine (297 publications), and Denollet Johan. (99 publications) were the most productive country, institutions, journal, and author, respectively. The three hotspots of the research were “The relationship between depression and CHD,” “depression and myocardial infarction,” and “The characteristic of women suffering depression after MI.” The four future research frontiers are predicted to be “treating depression in CHD patients with multimorbidity,” “psychometric properties of instruments for assessing depression and anxiety in CHD patients,” “depression or anxiety in post-PCI patients,” and “other mental diseases in CHD patients.” Bibliometric analysis of the association between CHD and depressive disorders might identify new directions for future research.


2020 ◽  
Author(s):  
Jiamin Cao ◽  
Nuo Wang ◽  
Shiying Hou ◽  
Xin Qi ◽  
Yu Chen ◽  
...  

BACKGROUND Research on Graves’ ophthalmopathy(GO) increased remarkably in recent two decades, however, few studies provided statistical analysis to these publications. OBJECTIVE The purpose of this study is to detect and analyze the emerging trend and collaboration networks on GO. METHODS GO-related publications were collected from 1999 to 2019 from the Web of Science Core Collection Database. The publications were collected after restricting the publications with the category of article or review and language of English. The content of bibliometric analysis included changes in the annual number of publications, journals, authors, countries and institutions, keywords, and references. RESULTS There were 3051 publications collected which met the criterion. The number of annual publications had an increasing trend over the last 20 years. THYROID published 183 assays in total related to GO and ranked first. SMITH TJ had the largest number of publications on GO(83). The United States had the largest number of articles(784) and highest centrality(0.18) among the countries that had published essays related to GO. The UNIV PISA, which belonged to Italy, contributed 114 articles that are ahead of other institutions on the number of articles related to GO. The most recent burst keywords (proliferation, rituximab, and selenium) and references may provide clues on an emerging trend of research and clinical decision. CONCLUSIONS This bibliometric analysis highlight countries, institutions, and authors which contributed to the publications on GO. And the possible emerging trends on GO research extracted from burst keywords and references may provided the clues on clinical decision making and future research.


Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3385
Author(s):  
Tauseef Ahmad ◽  
Muhammad Imran ◽  
Kabir Ahmad ◽  
Muhammad Khan ◽  
Mukhtiar Baig ◽  
...  

Background: Fascioliasis is a zoonotic neglected tropical disease caused by Fasciola hepatica and F. gigantica. In endemic regions, fascioliasis represents a huge problem in livestock production and significantly threatens public health. The present study was performed to assess the key bibliometric indicators, plot the global research outcome, and strive to find the research frontiers and trends in fascioliasis. Methods: A descriptive bibliometric and visualized study was conducted. The data were extracted from the Web of Science Core Collection (WoSCC) database. The WoSCC was searched using key terms covering a wide range of synonyms related to the causative agent (Fasciola) and the disease (fascioliasis). The database search was performed for the period from the inception of WoSCC until 3 October 2021. The downloaded data were exported into VOSviewer software version 1.6.17 for Windows to construct co-authorship countries, keywords co-occurrence, bibliographic coupling sources, and citation and documents network visualization. Results: A total of 4165 documents were included in this bibliometric analysis. The included documents were published between the years 1913 and 2021 from 116 countries, mainly from the United States of America (USA) (n = 482, 11.6%). The most prolific year was 2018 (n = 108). The journal that attracted the most publications was Veterinary Parasitology (n = 324), while the most productive author in this area was Rondelaud D (n = 156). In terms of total link strength (TLS), the most influential country was Spain (TLS = 236), followed by the USA (TLS = 178). Conclusion: This study is of value for veterinarians, doctors, and researchers to explore insights into research frontiers and trends in research on fascioliasis. The number of publications on fascioliasis has increased over time. Above 35% of publications have been produced by the USA, France, England, and Spain. “Fasciola hepatica” and “cattle” were the most dominant and widely used keywords. Research collaboration should be established among the researchers from developing countries with developed countries to learn new advancements and effective control strategies for fascioliasis.


2022 ◽  
Author(s):  
Zhaozhao Hui ◽  
Xiaoqin Wang ◽  
Ying Zhou ◽  
Yajing Li ◽  
Xiaohan Ren ◽  
...  

Abstract Background: Cognitive frailty relates to various adverse health outcomes of older adults and is proposed as a new target of healthy ageing. This study aimed to analyze the status, hotspots, and emerging trends / frontiers of global research on cognitive frailty.Methods: Articles and reviews related to cognitive frailty of older people published from 2013 to 2021 were retrieved from the Web of Science Core Collection (WoSCC) database on 26 November 2021. CiteSpace 5.8.R3 was used to conduct the collaboration analysis, document co-citation analysis, and keyword co-occurrence analysis.Results: A total of 2,077 publications were included. There has been a rapid growth of publications on cognitive research since 2016. The United States, Italy, England, and Australia were the leading research centers of cognitive frailty; however, China has recently focused on this topic. The National Center for Geriatrics and Gerontology and Shimada H. were found to be the most prolific institution and author, respectively. Co-citation analysis identified 16 clusters, of which the largest was cognitive frailty. The most frequently occurred keyword was older adult, followed by cognitive impairment, frailty, risk, dementia, prevalence, mortality, health, and Alzheimer’s disease. Burst keyword detection revealed a rising interest in cognitive frailty models.Conclusions: By analyzing the publications over the past years, this study provides a comprehensive analysis of cognitive frailty research. A variety of visualized networks offer an in-depth understanding of the countries / regions, institutions, authors, hotspots, and research frontiers.


2020 ◽  
pp. 016555152097744
Author(s):  
Binh Pham-Duc ◽  
Trung Tran ◽  
Thao-Phuong-Thi Trinh ◽  
Tien-Trung Nguyen ◽  
Ngoc-Trang Nguyen ◽  
...  

Bibliometric analysis of 3105 publications retrieved from the Scopus database was conducted to evaluate bibliographic content of scientific output on social sciences in Vietnam, for the 2000–2019 period. Our main findings show that the number of publications on social sciences from Vietnam has increased significantly over the last two decades, and there was a spike in the scientific output for the recent three years when the number of publications accounted for 53.76% of the collection. The most productive authors came from a few public research institutes with strong resources as the top 10 institutions participated in 44.22% of the collection. Vietnamese scholars tend not to submit their works to high-ranking journals since five Q1 journals in the top 10 publishing journals published only 6.17% of the collection. For international collaboration, Australia and the United States ranked first and second based on the number of publications and citations. Other countries in top 10 mostly located in Europe and Asia. Research topics were diverse focusing on gender, poverty, HIV, higher education and sustainable development. We suggest that supporting policies and funding need to be provided to help Vietnamese scholars improve their works, and to boost their scientific production in the future.


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