scholarly journals Traditional Chinese Medicine Body Constitutions and Psychological Determinants of Depression among University Students in Malaysia: A Pilot Study

Author(s):  
Sin Yap ◽  
Chai Foo ◽  
Yang Lim ◽  
Foong Ng ◽  
Sherina Mohd-Sidik ◽  
...  

Depression is commonly observed in university students, who are a high risk group for developing psychiatric disorders during adulthood. This study aimed to determine the prevalence of depression and its traditional Chinese medicine body constitutions and psychological determinants among university students in Malaysia. A cross-sectional pilot study was conducted between 9 and 28 September 2020 among 80 university students in Malaysia. Participants completed online survey questionnaires, including the validated Patient Health Questionnaire (PHQ-9), Constitution in Chinese Medicine Questionnaire (CMCQ), Dysfunctional Attitude Scale (DAS), Depression Anxiety Stress Scale (DASS-21) stress subscale, Perceived Stress Scale (PSS-10), and Rosenberg Self-Esteem Scale (RSES), which assess depression, body constitution, dysfunctional attitude, stress, perceived stress, and self-esteem. Multiple linear regression analyses were performed to determine the associated risk factors for depression. The overall prevalence of depression among university students was 33.8%. The multiple regression analysis showed a significant relationship between depression and qi-stagnation constitution (B = 0.089, p = 0.011), balanced constitution (B = −0.077, p = 0.049), and self-esteem (B = −0.325, p = 0.001). Our findings suggest that some traditional Chinese medicine body constitutions and self-esteem are significant risk factors affecting depression among university students. Identifying risk factors of depression is vital to aid in the early detection of depression among university students.

2020 ◽  
Vol Volume 16 ◽  
pp. 2389-2396
Author(s):  
Shahnawaz Anwer ◽  
Md Dilshad Manzar ◽  
Ahmad H Alghadir ◽  
Mohammed Salahuddin ◽  
Unaise Abdul Hameed

PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0189543 ◽  
Author(s):  
Wei Lu ◽  
Qian Bian ◽  
Wenzheng Wang ◽  
Xiaoling Wu ◽  
Zhen Wang ◽  
...  

2020 ◽  
Author(s):  
Shu Ling Tan ◽  
Malte Jetzke ◽  
Vera Vergeld ◽  
Carsten Müller

BACKGROUND Mental health is an emerging topic on university campuses, with students reporting higher levels of psychological distress than the general population of the same age. Increasing physical activity and reducing sedentary time have been proved promising measures to promote mental health in the general population. However, to derive and implement effective measures to promote mental health among university students, further exploration of the associations between physical activity, sedentary time, and perceived stress in this specific setting is needed. OBJECTIVE This study aims to identify associations between physical activity, sedentary time, and perceived stress after controlling for sociodemographic and behavioral variables among university students in Germany. We hypothesize that perceived stress is inversely related to physical activity and positively associated with sedentary time. Furthermore, we hypothesize that combined associations of concurrently high physical activity and low sedentary time on perceived stress are stronger compared with either alone and that the association between physical activity and perceived stress depends on activity intensity. METHODS We conducted cross-sectional analyses from a large-scale internet-based student health survey (n=4189; response rate=10.0%). Physical activity, sedentary time, and engaging in moderate and vigorous activity intensities were assessed using the International Physical Activity Questionnaire Short Form with categorization into low, intermediate, and high levels. We measured perceived stress using the 10-item Perceived Stress Scale (range 0-40). RESULTS The results indicate that higher physical activity and lower sedentary time are associated with reduced levels of perceived stress. Following adjustment for gender, BMI, income, fruit and vegetable intake, alcohol consumption, and sleep quality, perceived stress scores were lower for students reporting high physical activity levels and low sedentary time compared with the least active and highly sedentary students (Perceived Stress Scale –2.2, 95% CI –2.9 to –1.5, <i>P</i>&lt;.001 for physical activity and –1.1, CI 95% –1.7 to –0.5, <i>P</i>&lt;.001 for sedentary time). Combined associations with perceived stress revealed that students concurrently reporting high total physical activity and low sedentary time reported the lowest perceived stress scores of all possible combinations following adjustment for confounders (Perceived Stress Scale –3.5, CI 95% –4.6 to –2.5, <i>P</i>&lt;.001 compared with students reporting low physical activity levels and concurrently high sedentary time). Associations between vigorous physical activities and perceived stress were not stronger compared with moderate activity intensities. CONCLUSIONS Self-reported physical activity and low sedentary time are favorably associated with perceived stress, while the intensity of physical activities seems to be of minor importance. These results help to effectively implement health-promoting measures on campus among university students through increasing physical activity and reducing sedentary time.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Tingshuai Wang ◽  
Shaodong Huang ◽  
Cong Wu ◽  
Na Wang ◽  
Rongzhen Zhang ◽  
...  

Liver disease is a leading cause of global morbidity and mortality, for which inflammation, alcohol use, lipid metabolic disorders, disturbance to bile acid metabolism, and endotoxins are common risk factors. Traditional Chinese Medicine (TCM) with its “holistic approach” is widely used throughout the world as a complementary, alternative therapy, due to its clinical efficacy and reduced side effects compared with conventional medicines. However, due to a lack of reliable scientific evidence, the role of TCM in the prevention and treatment of liver disease remains unclear. Over recent years, with the rapid development of high-throughput sequencing, 16S rRNA detection, and bioinformatics methodology, it has been gradually recognized that the regulation of intestinal microbiota by TCM can play a substantial role in the treatment of liver disease. To better understand how TCM regulates the intestinal microbiota and suppresses liver disease, we have reviewed and analyzed the results of existing studies and summarized the relationship and risk factors between intestinal microbiota and liver disease. The present review summarizes the related mechanisms by which TCM affects the composition and metabolites of the intestinal microbiome.


2020 ◽  
Author(s):  
Cyrille Kossigan KOKOU KPOLOU ◽  
Askar Jumageldinov ◽  
Sunyoung Park ◽  
Nicolas Nieuviarts ◽  
Pari-Gole Noorishad ◽  
...  

<p><i>Background</i>: Previous studies have indicated that university students constitute a higher risk population for mental health problems, especially for depression. Yet, there appears to be a lack of literature addressing a such issues in France. The present study aimed to estimate the prevalence rates of depression, its sociodemographic correlates in French university students (FUS), and to examine whether individual resilience resources moderated and mediated the relationship between perceived stress and depressive symptoms. </p> <p><i>Methods</i>: The data were collected through web-based questionnaires. The sample included 1435 FUS with a mean age of 20.5 (<i>SD </i>= 3.38) years. Participants completed the Beck Depression Inventory (BDI-II), the Perceived Stress Scale, the Brief Resilience Scale, and a sociodemographic questionnaire. Descriptive, multiple logistic regression and mediation analyses were used. </p> <p><i>Results</i>: With respect to the BDI-II’s cutoff scores, 20.3% and 22.8% were positive to moderate and severe depression, respectively (43.1%). Gender and education attainment appeared as moderate risk factors when accounting for cumulative effect of perceived stress and individual resilience. Resilience was found to buffer and mediate partially the perceived stress–depression relationship. </p> <p><i>Conclusion</i>: The prevalence of depression was higher in FUS, as similar to those reported in</p> <p>previous studies. The amount of academic and daily stress explained this prevalence. University students with low resilience level were more at risk. Interventions with aim to improving resilience skills could help to mitigate the negative effects of stress and to promote mental health in this population.</p>


Work ◽  
2021 ◽  
pp. 1-7
Author(s):  
Jonas Vinstrup ◽  
Kenneth Jay ◽  
Markus Due Jakobsen ◽  
Lars L. Andersen

BACKGROUND: While the psychosocial work environment within the hospital sector is a topic of great debate, surveys assessing stress often do not differentiate between stress related to work- and private life. Identifying risk factors associated with these domains of daily life would help improve policies as well as target relevant treatment options. Therefore, the aim of this study was to evaluate associations between stress during to work- and private time with Cohen’s Perceived Stress Scale (CPSS). METHODS: Perceived stress was assessed by the full version of CPSS (scores 0–40) as well as by two single-item questions related to stress related to work- and private life, respectively. Associations between these single-items and CPSS were modelled using general linear models controlling for lifestyle factors. RESULTS: Overall, stress due to both work- and private time was strongly associated with CPSS scores. In the full population (n = 3,600), “never experiencing stress” during both work- and private time was associated with low stress scores (6.0, 95%CI 5.1–6.9). “Never experiencing” work-related stress but experiencing private time stress “very often” was associated with high stress scores (22.4, CI 19.8–25.1). Likewise, experiencing work-related stress “very often” but “never experiencing” private time stress was also associated with high stress scores (22.2, CI 20.3–24.2). Lastly, Spearman’s r between the full CPSS and the two single-item questions about work- and private time stress were 0.62 (p <  0.0001) and 0.52 (p <  0.0001), respectively, while the two items were only weakly correlated (r = 0.32). CONCLUSION: The present study shows that perceived stress due to both work and private time is strongly associated with Cohen’s Perceived Stress Scale scores. The results illustrate the feasibility of using single-item questions related to work- and private time in identifying domain-specific risk factors for psychosocial stress.


Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 32-33
Author(s):  
Jing Zhang ◽  
Baoan Chen

Objectives The aim of this part is to analyze the efficacy of R-CHOP regimen in the treatment of diffuse large B-cell lymphoma (DLBCL), and to explore the risk factors of relapse and refractory DLBCL by analyzing the clinical characteristics of patients, and to study the predictive efficacy of these factors on the prognosis of patients. Methods Clinical data of 71 patients with de novo DLBCL from December 2012 to December 2018 in the Department of Hematology, Zhongda Hospital Affiliated to Southeast University were collected and retrospectively analyzed. The patients with DLBCL were divided into two groups according to who were refractory or relapse after initial therapy. Then the response rate and high-risk factors of refractory and relapse lymphoma were analyzed by the chi-square test and Mann-Whitney U test. Besides, Overall survival (OS) curves and prognosis factors were estimated by the Kaplan-Meier method, Log-rank test and Cox proportional hazard regression analysis. Furthermore, the patients were divided into two groups according to the IPI score, and a comparative analysis of survival rate was performed between subgroups. Results 1.There were 71 patients who were diagnosed with DLBCL, in which 45 cases achieved complete remission (CR), 11cases achieved partial remission (PR), and the total remission rate was 78.9%. By the end of the follow-up, 25 cases (35.2%) experienced refractory and relapse, and 17 cases (23.9%) died, with an average OS of 60 months and an average EFS of 52 months. 2.Univariate analysis showed that the B symptoms (P&lt; 0.001), low levels of Hb (P&lt; 0.001) and LMR (P&lt; 0.001), high levels of NLR (P= 0.042), β2-MG (P= 0.011), hs-CRP (P= 0.002) and LDH (P= 0.017) were significantly related with refractory and relapse. Multivariate Logistic analysis showed B symptoms (P= 0.033) and high levels of β2-MG (P= 0.048) were independent risk factors for refractory and relapse lymphoma. 3.Kaplan-Meier method analysis showed that the OS of patients with either B symptoms (P&lt; 0.001), low levels of Hb (P= 0.008) and LMR (P= 0.005), or high levels of β2-MG (P= 0.007), hs-CRP (P= 0.008) and LDH (P= 0.002) were significantly shorter than that of control group. Additionally, Cox regression methods analysis showed that B symptoms (P= 0.026) and high β2-MG (P= 0.038) were independent prognosis factors for DLBCL. 4.Kaplan-Meier analysis of survival between the low-risk IPI and high-risk IPI groups showed that the OS of patients with B symptoms in both IPI low-risk group (P = 0.013) and IPI high-risk group (P = 0.027) weresignificantly shorter than those without B symptoms. Moreover, there was no significant difference in the OS of patients with either low levels of Hb and LMR,or high levels of LDH, β2-MG, and hs-CRP in both group (P &gt; 0.05). Conclusion B symptoms and high levels of β2-MG are independent risk factors for relapse and refractory, and are expected to be incorporated into the new prognostic score system. Part two: Clinical study of maintenance therapy for DLBCL Objectives The aim of this part was to explore the efficacy of different maintenance therapies on DLBCL, and evaluate the safety of rituximab and traditional Chinese medicine maintenance therapy. Methods Clinical data of 71 patients with de novo DLBCL from December 2012 to December 2018 in the Department of Hematology, Zhongda Hospital Affiliated to Southeast University were collected and retrospectively analyzed. Follow-up and study whether patients have undergone maintenance therapy and maintenance therapy regimen. Results Of the 71 patients with DLBCL, 11 cases received maintenance therapy after CR, of which 6 cases were maintained with rituximab and 5 cases maintained with traditional Chinese medicine (TCM). The median follow-up time was 27 months. By the end of the follow-up, none of the 11 cases had relapsed and no treatment-related adverse reactions occurred. In particular, 2 patients received autologous hematopoietic stem cell transplantation after achieving CR, and then took TCM for maintenance therapy. No tumor recurrence was seen during follow-up and the clinical indicators were normal and stable. Conclusion Rituximab and TCM have good efficacy and safety in the maintenance treatment of DLBCL. TCM maintenance treatment shows unique advantages, and it is expected to be widely used in clinic after further verification in the future. Key words Diffuse large B-cell lymphoma; maintenance therapy; rituximab; traditional Chinese medicine Disclosures No relevant conflicts of interest to declare.


2012 ◽  
Vol 110 (2) ◽  
pp. 469-474 ◽  
Author(s):  
Allison Hubbs ◽  
Eva I. Doyle ◽  
Rodney G. Bowden ◽  
Robert D. Doyle

The purpose of this study was to identify population and sex-specific relationships between perceived stress, self-esteem, and physical activity in college students. 90 students, ages 18 and older and enrolled in five sections of a health and human behavior class during the spring 2010 semester, were contacted for this study with 74 consenting to serve as study participants. Each participant completed three surveys: the Rosenberg Self-Esteem Scale, the Perceived Stress Scale, and the International Physical Activity Questionnaire. Significant correlations were observed between perceived stress and self-esteem in men, and in women. Physical activity was not significantly correlated with perceived stress or self-esteem.


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