scholarly journals Differences in Incidence of Acute Viral Hepatitis between Foreigners and Autochthonous Population in Italy

Author(s):  
Franca D’Angelo ◽  
Luigina Ferrigno ◽  
Annamaria Mele ◽  
Valeria Alfonsi ◽  
Silvia Declich ◽  
...  

Background: In European countries, the prevalence of HBV and HCV in refugees and migrants tends to reflect the prevalence in their countries of origin. The aim of this study is to analyse acute viral hepatitis cases diagnosed in Italy among foreign citizens and to compare incidence rates in foreigners and Italians. Methods: We analysed the cases of each viral hepatitis type among foreigners. Standardised incidence rates were compared between natives and foreigners. Results: Between 2004 and 2019, 15,872 cases of acute viral hepatitis were notified by 10 Italian regions, 14.8% among foreign citizens. Until 2012, the percentage increased gradually, while a fluctuating trend set in from 2013 onwards; in 2019, 23.9% of cases were foreigners. Data from the SEIEVA surveillance show higher standardised incidence rates of hepatitis A and B among foreign citizens; no significant difference emerged between Italians and foreigners in terms of their hepatitis C incidence. Conclusions: foreign citizens have an increased incidence of hepatitis A and B. Regarding hepatitis A, vaccination is strongly recommended to foreigners travelling to their countries of origin. Screening tests for hepatitis B and C infection should be offered to newly arrived migrants from high prevalence countries, or having specific risk factors.

2016 ◽  
Vol 21 (3) ◽  
pp. 130-135
Author(s):  
A. A Trisko ◽  
Marina G. Avdeeva ◽  
N. V Kolesnikova

The goal - improving the quality of the diagnosis of acute infectious mononucleosis (IM) in adults on the basis of a comparative study of cytokine status in MI, acute tonsillitis and acute viral hepatitis. Materials and methods. We observed three groups of patients hospitalized in «Specialized Clinical Hospital of Infectious Diseases of the Ministry of Health of the Krasnodar Territory» in 2012-2014: 29 patients with myocardial infarction (group 1), 25 - with acute tonsillitis (group 2), 19 - with acute viral hepatitis (group 3) and the control group. The groups were matched by sex, age and severity of the disease. In the acute phase of the disease the level of cytokines IL-1a, IL-1β, RaIL-1, IL-4, INF-y in serum was studied by ELISA. Results. At the height of the infectious mononucleosis increased content of IL-1a, IL-1β and INF-y was observed. In acute viral hepatitis significant increase in IL-1β, a less pronounced increase in INF-y, and no increase in IL-1a were registered. Acute tonsillitis is characterized by no increase in IL-1a and smaller increase in INF-y, compared to infectious mononucleosis. Significant difference between infectious mononucleosis and acute tonsillitis was a considerable rise of IL-1a and INF-y in first case. Acute viral hepatitis differs from infectious mononucleosis with pronounced increase in IL-1β. Conclusion. Determined significant intergroup cytokine status differences in patients with infectious mononucleosis, acute tonsillitis, and acute viral hepatitis may be helpful as additional diagnostic criteria for well examined infections in adults.


2018 ◽  
pp. 1-2
Author(s):  
Dr. Dayananda Ingudam

BACKGROUND: Hepatitis is the most common cause of acute viral hepatitis. It causes severe, often fatal disease in adults especially in those with underlying liver dysfunction but is mostly asymptomatic in children. The present study was conducted with the aimed to nd the prevalence and seasonal variation of HAVinfection in patients attending JNIMS hospital. METHODOLOGY:Across sectional hospital based study was conducted in the department of Microbiology, JNIMS, Imphal, Manipur. Rapid immunochromatographic assay was performed for the detection of IgM antibody to HAVin human serum. RESULTS: Out of the 84 serum samples 20(23.80%) was found to be positive for hepatitis IgM, of which 11 (55%) were found in males and 9(45%) were found in females. A seasonal increase in incidence of HAV infection was found during the rainy season of January – March (50%) and April – June (35%). CONCLUSION: The global seroepidemiology of hepatitis A is changing in many developing nations giving rise to unique non immune adolescent and adult populations emerging in endemic regions thereby conferring a risk of developing severe hepatitis A. Hence, nding the prevalence, seasonal variation and timely detection of HAVinfection will help in minimising the development of further complication


2011 ◽  
Vol 153 (2) ◽  
pp. e34-e36 ◽  
Author(s):  
Yae Min Park ◽  
Woong Chol Kang ◽  
Kwen-Chul Shin ◽  
Mi Seung Shin ◽  
Wook Jin Chung ◽  
...  

Author(s):  
Karlla A A Caetano ◽  
Fabiana P R Bergamaschi ◽  
Megmar A S Carneiro ◽  
Raquel S Pinheiro ◽  
Lyriane A Araújo ◽  
...  

Abstract Background People living in settlement projects represent an emergent rural population in Brazil. Data on their health is scarce and there are no data on viral hepatitis in this population. This study investigated the epidemiology of viral hepatitis A-E in residents of settlement projects in central Brazil. Methods During 2011 and 2012, 923 people living in rural settlements in central Brazil were interviewed and tested to estimate the prevalence of exposure to viral hepatitis A-E, to identify the circulating hepatitis B virus (HBV)/hepatitis C virus (HCV) genotypes and risk factors for HBV exposure and to evaluate adherence to the hepatitis B vaccination series. Results Overall, 85.9, 3.9, 0.4 and 17.3% of individuals showed evidence of exposure to hepatitis A virus (HAV), hepatitis E virus, HCV and HBV, respectively. Among HBV-DNA positive samples (n=8), subgenotypes A1 (n=3) and A2 (n=1) and genotype D/subgenotype D3 (n=4) were identified. Hepatitis D virus superinfection was detected in 0/16 HBsAg-positive participants. A total of 229 individuals showed serological evidence of HBV vaccination. In total, 442 settlers were eligible for vaccination, but only 150 individuals completed the vaccine series. All anti-HCV-positive samples (n=4) were also HCV-RNA positive and identified as subtype 1a. Conclusions The intermediate endemicity of HAV, the higher prevalence of HBV exposure compared with urban areas and the low compliance with HBV vaccination requires preventive measures focused on rural populations, emphasizing the need for HAV and HBV vaccination.


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