scholarly journals Moderate High Caloric Maternal Diet Impacts Dam Breast Milk Metabotype and Offspring Lipidome in a Sex-Specific Manner

2020 ◽  
Vol 21 (15) ◽  
pp. 5428 ◽  
Author(s):  
Marie-Cécile Alexandre-Gouabau ◽  
Agnès David-Sochard ◽  
Anne-Lise Royer ◽  
Patricia Parnet ◽  
Vincent Paillé

Lactation is a critical period during which maternal sub- or over-nutrition affect milk composition and offspring development that can have lasting health effects. The consequences of moderate high-fat, high-simple carbohydrate diet (WD) consumption by rat dams, during gestation and lactation, on milk composition and offspring blood lipidome and its growth, at weaning, were investigated by using a comprehensive lipidomic study on mass-spectrometric platform combined to targeted fatty- and free amino-acids analysis. This holistic approach allowed clear-cut differences in mature milk-lipidomic signature according to maternal diet with a similar content of protein, lactose and leptin. The lower WD-milk content in total fat and triglycerides (TGs), particularly in TGs-with saturated medium-chain, and higher levels in both sphingolipid (SL) and TG species with unsaturated long-chain were associated to a specific offspring blood-lipidome with decreased levels in TGs-containing saturated fatty acid (FA). The sexual-dimorphism in the FA-distribution in TG (higher TGs-rich in oleic and linoleic acids, specifically in males) and SL species (increased levels in very long-chain ceramides, specifically in females) could be associated with some differences that we observed between males and females like a higher total body weight gain in females and an increased preference for fatty taste in males upon weaning.

Author(s):  
A. Santra ◽  
N.N. Pathak

Twenty 9-month-old crossbred calves were divided into 2 equal groups (A and B; n = 10). The feeding trial was conducted for 119 days to study the effect of concentrate supplementation on body immune response and blood metabolites in calves. The concentrate and roughage (wheat straw) ratio in the diet of Groups A and B was 60:40 and 30:70, respectively. Daily dry matter intake was significantly (P < 0.01) higher in Group A than in Group B, which also resulted in significantly higher (P < 0.01) total body weight gain in the former group. Protein, albumin, globulin, total and differential leukocyte count in blood were similar in the 2 groups but blood glucose level was higher (P < 0.05) in the calves of Group A. There was no difference in body immune response between the groups, which indicated that body immune response of animals is not significantly influenced by restricted concentrate feeding.


Author(s):  
G. Rajkumar ◽  
M. T. Dipu ◽  
K. Lalu ◽  
K. Shyama ◽  
P. S. Banakar

An experiment was conducted to evaluate the effect of maize green fodder produced by hydroponics system on the performance of eighteen weaned crossbred calves and Calves were divided into three groups T1, T2 and T3 of six each as uniformly. The calf starter in dietary treatments T1, T2 and T3 contained 24, 20 and 17 per cent of Crude Protein (CP), respectively and 70 per cent Total Digestible Nutrients (TDN). The T2 and T3 treatments were made iso-nitrogenous with T1 by supplementing hydroponics maize fodder. The results obtained in the present study showed significant difference among different treatment groups regarding Dry matter intake (DM), total body weight gain, Average daily gain (ADG) and Feed conversion ratio (FCR) with a higher (P less than 0.05) values observed for calves belonging to T3 than groups T1 and T2. Data on digestibility of nutrients does not reveal any difference (P>0.05) among treatment groups. Cost per kg gain was significantly (P less than 0.05) lower in T3 (Rs.102.14) than groups T2 (Rs. 111.64) and T1 (Rs. 119.82). On conclusion, feeding of hydroponics maize fodder as a partial feed substitute of calf starter on protein basis at seven per cent level improves the DM intake, total body weight gain, ADG and lowers the cost per kg body weight gain.


1970 ◽  
Vol 38 (1-2) ◽  
pp. 102-107 ◽  
Author(s):  
AKM Masum ◽  
MN Islam ◽  
MAS Khan

An experiment was conducted to study the utilization of soymilk as milk replacer for raising calves. Nine crossbred calves were selected and divided into three groups on the basis of their body weight and genotype. The calves of group A were reared by cow milk, group B reared by strained soymilk and group C reared by unstrained soymilk. It was found that, total body weight gain of group A, B and C were 13.933 ± 1.222, 13.800 ± 0.917 and 13.233 ± 1.537 Kg, respectively. There was no significant difference among the three groups of calves. Non-significant differences were also seen for increment in wither height (5.588 ± 0.508, 5.419 ± 0.529 and 5.080 ± 0.440 cm, respectively), length (6.096 ± 0.440, 5.927 ± 0.388 and 5.503 ± 0.388 cm, respectively) and heart-girth (5.842 ± 0.440, 5.588 ± 0.916 and 5.419 ± 0.388 cm, respectively) of calves. Economic analysis showed that soymilk was cheaper than cow milk (Tk. 8.0 vs Tk. 44.0). It can be concluded that soymilk as milk replacer could be used successfully for raising dairy calves. DOI: http://dx.doi.org/10.3329/bjas.v38i1-2.9918 BJAS 2009; 38(1-2): 102-107


Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4243
Author(s):  
Elena Zambrano ◽  
Guadalupe L. Rodríguez-González ◽  
Luis A. Reyes-Castro ◽  
Claudia J. Bautista ◽  
Diana C. Castro-Rodríguez ◽  
...  

We investigated if supplementing obese mothers (MO) with docosahexaenoic acid (DHA) improves milk long-chain polyunsaturated fatty acid (LCPUFA) composition and offspring anxiety behavior. From weaning throughout pregnancy and lactation, female Wistar rats ate chow (C) or a high-fat diet (MO). One month before mating and through lactation, half the mothers received 400 mg DHA kg−1 d−1 orally (C+DHA or MO+DHA). Offspring ate C after weaning. Maternal weight, total body fat, milk hormones, and milk nutrient composition were determined. Pups’ milk nutrient intake was evaluated, and behavioral anxiety tests were conducted. MO exhibited increased weight and total fat, and higher milk corticosterone, leptin, linoleic, and arachidonic acid (AA) concentrations, and less DHA content. MO male and female offspring had higher ω-6/ ω-3 milk consumption ratios. In the elevated plus maze, female but not male MO offspring exhibited more anxiety. MO+DHA mothers exhibited lower weight, total fat, milk leptin, and AA concentrations, and enhanced milk DHA. MO+DHA offspring had a lower ω-6/ω-3 milk intake ratio and reduced anxiety vs. MO. DHA content was greater in C+DHA milk vs. C. Supplementing MO mothers with DHA improves milk composition, especially LCPUFA content and ω-6/ω-3 ratio reducing offspring anxiety in a sex-dependent manner.


2019 ◽  
Vol 60 (1) ◽  
pp. 60-78
Author(s):  
Ivana Miletić ◽  
Gorana Jelić Mrčelić ◽  
Merica Slišković ◽  
Maja Pavela-Vrančić ◽  
Stjepan Orhanović ◽  
...  

Capture-based tuna aquaculture rates as one of the most important aquaculture activities in Cro-atia, where juvenile tuna are reared in cages for over a year long period in order to increase substan-tially their weight. The aim of this study was to assess the effect of length and intensity of feeding on biochemical composition (total fat, moisture, dry matter, carbohydrates and protein content) of tuna (Thunnus thynnus) white muscle tissues in newly caught tuna prior to feeding (NCTPF) versus far-med tuna kept in rearing circular cages in the Vela Grska Bay, Adriatic Sea (LAT 43°17’40,6984”N, LONG 016°28’58,4315”E (WGS84)) between 2001 and 2004. Farmed tunas from all cages were fed with the feed consisting of domestic small pelagic fish, or with mixtures containing North Sea herring (Clupea harengus) and Sardina pilchardus, for five months (cage 3), eight months (cage 4) or 21 months (cages 1 and 2). A low content of moisture and high content of dry matter including fat was observed in farmed tuna muscles compared to wild-caught tuna. In farmed tuna muscles, measured moisture was 55.26% in cage 1, 39.95% in cage 2, 54.64% in cage 3 and 49.70% in cage 4. These results are significantly lower than moisture measured in NCTPF (80.36%). Content of dry matter found in farmed tuna muscles also differed greatly between wild tuna (19.64%) and far-med tuna, but also between the cages (44.74% in cage 1, 60.05% in cage 2, 45.36% in cage 3 and 50.30% in cage 4). In NCTPF, muscle tissues total fat encompassed less than 1% of the total body weight, while it reached over 20% of total body mass in farmed fed tuna (20.62% in cage 1, 42.50% in cage 2, 20.97% in cage 3 and 20.57% in cage 4). These results demonstrate that high fat content can be achieved already after five months of intensive feeding. Higher content of proteins was also found in aquacultured tuna (18.60% in cage 1, 16.00% in cage 2, 15.09% in cage 3 and 20.58% in cage 4) compared to wild-caught tuna (13.77%). There were no differences in carbohydrates con-tent between tuna farmed in different cages and NCTPF tuna, indicating glycogen as a less optimal indicator of muscle tissue quality in farmed tuna of the present study.


2019 ◽  
Vol 20 (1) ◽  
pp. 62-66
Author(s):  
Magdy Amer

This study was performed on to evaluate the effect of some probiotic strains (Pediococcus acidophilus and Pedicoccus pentosaceus) on performance, blood picture and some biochemical parameters in serum of treated calves (10 weaned calves 90-115 kg). Calves were classified into 2 equal groups (each of 5 calves). The 1st group was served as the control group while the second group was given Maxboost® (20gm/head/day) in drinking water (after fermentation for 2-3 hours) for five months. Calves were weighed monthly to calculate the body weight gain till the end of the experiment whole blood weight and serum were collected from both groups at 1st, 2nd, 3rd, 4th and 5th month. Results revealed a significant increase in total body weight, body gain, total erythrocytes count, hemoglobin content, total leucocytes count, total protein and mean corpuscular hemoglobin. On the other hand, there were a significant decrease in serum aspartate transaminase (AST), serum alanine transaminase (ALT) and urea in pediococcus treated group compared to the control one.


1991 ◽  
Vol 71 (4) ◽  
pp. 1223-1231 ◽  
Author(s):  
Marie Letendre ◽  
Jean F. Bernier ◽  
Christiane L. Girard ◽  
J. Jacques Matte

In the first of two trials, 24 piglets (2 wk old) were used to measure the dose–response curve of serum folates after intramuscular injections of folic acid (0, 10, 20 or 30 mg). Administration of 10 mg of folic acid was sufficient (P < 0.01) to prevent the decrease of serum folates observed 1 wk after weaning. In the second trial, 72 piglets (2 wk old) were used to study the effect of repeated intramuscular injections of folic acid (0 or 2.5 mg kg−1 of body weight) on hematological status, liver development, and concentrations of serum and hepatic folates, as well as on growth performance up to 10 wk of age. Serum and liver folates were increased (P < 0.01) by repeated injections of folic acid. However, no treatment effects (P > 0.10) were observed on total content of DNA, RNA and protein in the liver. Hemoglobin, hematocrit, total body weight gain, gain: feed ratio and total feed intake were also not influenced (P > 0.10) by the injections of folic acid. Therefore, although a decrease in serum folates is observed during the weaning period, it does not seem to have detrimental effects on the growth performance of weanling piglets. Key words: Folic acid, folates, growth performance, piglets, weaning


1983 ◽  
Vol 54 (3) ◽  
pp. 192-199
Author(s):  
Shigeki KOBAYASHI ◽  
Yutaka YOSHIDA ◽  
Sakae KAWASHIMA

2021 ◽  
Vol 31 (2) ◽  
pp. 161-166
Author(s):  
G. S. Ojewola ◽  
E. N. Nwachukwu ◽  
S. F. Abasiekong ◽  
A. H. Akinmutimi ◽  
O. A. Oluwafisayo

The biological and economic efficiencies of Ronozyme™P as a substitute for bone meal in female Turkey poults was investigated. A total of eighty local female poults were brooded and fed commercial broiler starter diet containing 23% CP and 2800kcal/kg ME from day-old to four weeks of age. Sixty (60) female poults were thereafter randomly selected and allotted to each of the four experimental groups of fifteen (15) birds each. Each diet was fed to triplicate groups of five poults for 8 weeks in a completely randomized design. A total of four isocaloric and isonitrogenous diets containing 25 CP and 2932kcal/kg ME were formulated. Each of the diets was supplemented with Ronozyme™P while inclusion level of bone meal was varied from diet 1 to 4 respectively. Of all the production and economic parameters considered only the mean daily feed intake was significantly (P < 0.05) influenced. Diet 2 proved to be the best, by having the best feed to gain ratio (2.55), and higher gross margin (₦1,356,35). The difference in the mean total body weight gain for the two diets (2,323.33 (D2) and 2,380.00g (D3)). It was concluded that 2% level of bone meal inclusion in poults diets proved better than diets having 3%, 1% and 1% respectively, especially when supplemented with 30g of Ronozyme™P as recommended. This will cut-down cost and also probably improve calcium and phosphorous availability and absorption.


2020 ◽  
Vol 16 (2) ◽  
pp. 142-154 ◽  
Author(s):  
Hadi Emamat ◽  
Zahra Yari ◽  
Hossein Farhadnejad ◽  
Parvin Mirmiran

Recent evidence has highlighted that fat accumulation, particularly abdominal fat distribution, is strongly associated with metabolic disturbance. It is also well-recognized that the metabolic responses to variations in macronutrients intake can affect body composition. Previous studies suggest that the quality of dietary fats can be considered as the main determinant of body-fat deposition, fat distribution, and body composition without altering the total body weight; however, the effects of dietary fats on body composition have controversial results. There is substantial evidence to suggest that saturated fatty acids are more obesogen than unsaturated fatty acids, and with the exception of some isomers like conjugate linoleic acid, most dietary trans fatty acids are adiposity enhancers, but there is no consensus on it yet. On the other hand, there is little evidence to indicate that higher intake of the n-3 and the n-6 polyunsaturated fatty acids can be beneficial in attenuating adiposity, and the effect of monounsaturated fatty acids on body composition is contradictory. Accordingly, the content of this review summarizes the current body of knowledge on the potential effects of the different types of dietary fatty acids on body composition and adiposity. It also refers to the putative mechanisms underlying this association and reflects on the controversy of this topic.


Sign in / Sign up

Export Citation Format

Share Document