scholarly journals Brain Mechanisms of COVID-19-Sleep Disorders

2021 ◽  
Vol 22 (13) ◽  
pp. 6917
Author(s):  
Oxana Semyachkina-Glushkovskaya ◽  
Aysel Mamedova ◽  
Valeria Vinnik ◽  
Maria Klimova ◽  
Elena Saranceva ◽  
...  

2020 and 2021 have been unprecedented years due to the rapid spread of the modified severe acute respiratory syndrome coronavirus around the world. The coronavirus disease 2019 (COVID-19) causes atypical infiltrated pneumonia with many neurological symptoms, and major sleep changes. The exposure of people to stress, such as social confinement and changes in daily routines, is accompanied by various sleep disturbances, known as ‘coronasomnia’ phenomenon. Sleep disorders induce neuroinflammation, which promotes the blood–brain barrier (BBB) disruption and entry of antigens and inflammatory factors into the brain. Here, we review findings and trends in sleep research in 2020–2021, demonstrating how COVID-19 and sleep disorders can induce BBB leakage via neuroinflammation, which might contribute to the ‘coronasomnia’ phenomenon. The new studies suggest that the control of sleep hygiene and quality should be incorporated into the rehabilitation of COVID-19 patients. We also discuss perspective strategies for the prevention of COVID-19-related BBB disorders. We demonstrate that sleep might be a novel biomarker of BBB leakage, and the analysis of sleep EEG patterns can be a breakthrough non-invasive technology for diagnosis of the COVID-19-caused BBB disruption.

2021 ◽  
Vol 10 (1) ◽  
pp. 36-41
Author(s):  
Seyed Hesamaddin Banihashemi ◽  
Ahmadreza Karimi ◽  
Hasti Nikourazm ◽  
Behnaz Bahmanyar ◽  
Dariush Hooshyar

The severe acute respiratory syndrome coronavirus 2 virus and its associated disease, called coronavirus disease 2019 (COVID-19), first appeared in Wuhan, China in December 2019 and quickly spread around the world. Coronavirus was officially named COVID-19 by the World Health Organization and was recognized as a pandemic due to its rapid spread worldwide. Based on the published data, it is hoped to provide a source for later studies and to help prevent and control the contagious COVID-19 and its characteristics, and considerations that surgeons and medical staff must observe during the epidemic.


mSphere ◽  
2020 ◽  
Vol 5 (2) ◽  
Author(s):  
Stuart Weston ◽  
Matthew B. Frieman

ABSTRACT The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the Hubei province in China in late 2019 demonstrates the epidemic potential of coronaviruses. The rapid spread of this virus across the world in only 2 months highlights the transmissibility of this family of viruses and the significant morbidity and mortality that they can cause. We highlight the current state of knowledge of coronavirus biology while answering questions concerning the current outbreak of SARS-CoV-2.


2021 ◽  
Vol 11 (03) ◽  
pp. 138-139
Author(s):  
Priyanka Anvekar ◽  
Manoj Kumar ◽  
Petras Lohana

The world was brought to a standstill by the rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), responsible for COVID-19. Initially recognized in Wuhan, China, in December 2019, it was announced to be a pandemic. It is known to spread from person to person via respiratory droplets such as saliva, cough and sneeze


Author(s):  
Houriiyah Tegally ◽  
Eduan Wilkinson ◽  
Marta Giovanetti ◽  
Arash Iranzadeh ◽  
Vagner Fonseca ◽  
...  

SummaryContinued uncontrolled transmission of the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for significant virus evolution. Here, we describe a new SARS-CoV-2 lineage (501Y.V2) characterised by eight lineage-defining mutations in the spike protein, including three at important residues in the receptor-binding domain (K417N, E484K and N501Y) that may have functional significance. This lineage emerged in South Africa after the first epidemic wave in a severely affected metropolitan area, Nelson Mandela Bay, located on the coast of the Eastern Cape Province. This lineage spread rapidly, becoming within weeks the dominant lineage in the Eastern Cape and Western Cape Provinces. Whilst the full significance of the mutations is yet to be determined, the genomic data, showing the rapid displacement of other lineages, suggest that this lineage may be associated with increased transmissibility.


2015 ◽  
Vol 16 (31) ◽  
pp. 1-7 ◽  
Author(s):  
Moss Pike

‘Gamification’ and games have become a popular trend in education, and have thus been given much attention in sessions at education conferences all over the world. But their rather rapid spread has also led to some misunderstandings about what they are and how they can be used in a classroom, largely owing to the wide variety of gamified courses and GBL-based classroom activities that have been popularised by educational media. Rather than serve as a panacea to fix classroom problems, however, gamification and GBL should be considered as just one of many tools, albeit quite powerful ones grounded in cognitive psychology, which can be used to create engaging and dynamic learning environments. After a short introduction to the ideas behind gamification and GBL and the brain science that makes them so powerful, an example of a gamified middle-school level Latin course will be described in detail.


2021 ◽  
Vol 10 (1) ◽  
pp. 47-54
Author(s):  
Lisda Amalia ◽  

Stroke is a condition when a person has a sudden neurological deficit caused by a disruption in the blood vessels of the brain. About 21-77% of stroke patients have sleep disorders that occur after a stroke. The sleep cycle is regulated by the brain and strokes can cause sleep disturbances due to abnormalities that can occur in the brain structures that regulate sleep. Post Stroke Sleep Disoder (PSSD) is the most common symptom after stroke. Sleep disorders after stroke include Sleep Disordered Breathing (SDB), insomnia, circadian rhythm sleep disturbance, hypersomnia, parasomnia and sleep-related movement disorders. Sleep has many benefits, one of which is the restoration of physical and mental functions, the consolidation of memory and improving the learning ability of a person both motorically and sensitively. Other studies have also shown a correlation between electrographic sleep time and cognitive function of stroke patients during recovery. Another experimental study also indicated that sleep disorders can increase the expression of neurocans, which are genes that inhibit nerve growth. Sleep disorders in stroke patients can reduce the efficiency and effectiveness of stroke rehabilitation


Author(s):  
Oxana Semyachkina-Glushkovskaya ◽  
Aysel Mamedova ◽  
Valeria Vinnik ◽  
Maria Klimova ◽  
Tingting Yu ◽  
...  

Here, we review findings and trends in sleep research in 2020-2021 demonstrating how COVID-19 and sleep disorders can induce the BBB leakage via neuroinflammation, which might contribute to the 'coronasomnia' phenomenon. The new studies suggest that the controlling of sleep hygiene and quality should be incorporated into the rehabilitation of COVID-19 patients. We also discuss perspective strategies for prevention of COVID-19-related BBB disorders. We demonstrate that sleep might be a novel biomarker of the BBB leakage and the analysis of sleep EEG patterns can be a breakthrough non-invasive technology for diagnosis of the COVID-19-caused BBB disruption.


2020 ◽  
Vol 5 (4) ◽  

14.8 million Indian struggle with vaginal depression. 1 in 8 suffers with symptoms of depression. The Pandemic facing the world has adding even more to those numbers. Depression affects how people think, feel and interact with others, face has walnut. Many sufferers have trouble doing day to day tasks and may think life has not worth living. Clinical depression has much more than a few days of feeling sad. Patients suffering with depression may feel an emptiness that cannot be filled, experience appetite changes, have thoughts of suicide, suffer with physical pain and can no longer find pleasure in activities that they once enjoyed. Family history, sleep disorders, traumatic events and medications can also cause and contribute to one’s Depression. Researchers have found that changes in the brain occur during depression. Some patients exhibit changes in serotonin levels, dopamine levels and norepinephrine levels in the brain. These neurotransmitters send signals to the synaptic passages in the brain that controls emotions. Researcher has seen poverty during early service. Also, when working in the power politics institute in Pune University researcher observed that trustee take poor employees to bed hungry. Our entire team at Aguirre Specialty Care would like to assure that have heightened all of precautionary standards and procedures to maximum levels to ensure the safety and well-being of our patients and staffs.


Author(s):  
Selma Büyükgöze

Brain Computer Interface consists of hardware and software that convert brain signals into action. It changes the nerves, muscles, and movements they produce with electro-physiological signs. The BCI cannot read the brain and decipher the thought in general. The BCI can only identify and classify specific patterns of activity in ongoing brain signals associated with specific tasks or events. EEG is the most commonly used non-invasive BCI method as it can be obtained easily compared to other methods. In this study; It will be given how EEG signals are obtained from the scalp, with which waves these frequencies are named and in which brain states these waves occur. 10-20 electrode placement plan for EEG to be placed on the scalp will be shown.


GYNECOLOGY ◽  
2020 ◽  
Vol 22 (5) ◽  
pp. 84-86
Author(s):  
Sergei P. Sinchikhin ◽  
Sarkis G. Magakyan ◽  
Oganes G. Magakyan

Relevance.A neoplasm originated from the myelonic sheath of the nerve trunk is called neurinoma or neurilemmoma, neurinoma, schwannoglioma, schwannoma. This tumor can cause compression and dysfunction of adjacent tissues and organs. The most common are the auditory nerve neurinomas (1 case per 100 000 population per year), the brain and spinal cord neurinomas are rare. In the world literature, there is no information on the occurrences of this tumor in the pelvic region. Description.Presented below is a clinical observation of a 30-year-old patient who was scheduled for myomectomy. During laparoscopy, an unusual tumor of the small pelvis was found and radically removed. A morphological study allowed to identify the remote neoplasm as a neuroma. Conclusion.The presented practical case shows that any tumor can hide under a clinical mask of another disease. The qualification of the doctor performing laparoscopic myomectomy should be sufficient to carry out, if necessary, another surgical volume.


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