scholarly journals Optimal Thyrotropin Suppression Therapy in Low-Risk Thyroid Cancer Patients after Lobectomy

2019 ◽  
Vol 8 (9) ◽  
pp. 1279 ◽  
Author(s):  
Lee ◽  
Jeon ◽  
Kim ◽  
Sung ◽  
Chung ◽  
...  
Keyword(s):  
Success Rate ◽  
Associated Factors ◽  
Clinical Characteristics ◽  
Clinical Results ◽  
Thyroid Stimulating Hormone ◽  
Low Risk ◽  
Maintenance Period ◽  
Papillary Thyroid ◽  
Clinical Factors ◽  
Factors Associated

Background: This study aimed to identify the clinical results after thyrotropin suppression therapy (TST) cessation and evaluated clinical factors associated with successful TST cessation. Methods: Patients who underwent lobectomy due to low-risk papillary thyroid carcinoma (PTC) were included in this study. We compared clinical characteristics and outcomes between patients who succeeded to stop TST and failed to stop TST. Results: A total of 363 patients were included in the study. One hundred and ninety-three patients (53.2%, 193/363) succeeded to stop TST. The independent associated factors for successful TST cessation were the preoperative thyroid-stimulating hormone (TSH) level and the maintenance period of TST. Patients with low TSH level showed a higher success rate for levothyroxine (LT4) cessation than patients with high TSH level (1.79 ± 1.08 and 2.76 ± 1.82 mU/L, p < 0.001). Patients who failed to discontinue TST showed a longer maintenance period of TST than patients who succeeded to discontinue TST (54.09 ± 17.44 and 37.58 ± 17.68 months, p < 0.001). Conclusions: Preoperative TSH level and maintenance period of TST are important factors for successful cessation of TST. If TST cessation is planned for patients who are taking LT4 after lobectomy, a higher success rate of TST cessation is expected with low preoperative TSH level and early cessation of LT4.

scholarly journals Death of Paediatric Surgical Patients in NICU of CMH, Dhaka

2021 ◽  
Vol 16 (1) ◽  
pp. 26-28
Author(s):  
Abu Daud Md Shariful Islam ◽  
Shams ud Din Elias Khan ◽  
Sabina Yasmeen ◽  
Julia Akhter Nira
Keyword(s):  
Neonatal Intensive Care ◽  
Clinical Characteristics ◽  
Caesarean Delivery ◽  
Intestinal Atresia ◽  
Surgical Patients ◽  
Hospital Death ◽  
Clinical Factors ◽  
Factors Associated ◽  
Novel Approaches ◽  
Hirschsprungs Disease

Introduction: The purpose of this study was to explore clinical characteristics and primary surgical diagnosis associated with in-hospital death in pediatric surgical patients admitted to the neonatal intensive care unit (NICU) of Combined Miilitary Hospital (CMH), Dhaka. Aim: To explore the clinical factors associated with in-hospital death in paediatric surgical patients admitted to the NICU over a period of 4 years in CMH Dhaka. Methods: This retrospective study includes all patients admitted to NICU of CMH Dhaka for paediatric surgical diseases between July 2013 and December 2017. Data analyzed to asses factors associated with in-hospital death. Results: A total of 72 cases were included and 61(84.7%) underwent surgery. Fifteen patients (20.8%) died while hospitalized in the NICU. The 5 most common surgical diagnoses were Anorectal Malformation, Intestinal Atresia/ Stenosis, Hirschsprungs disease, Intestinal perforation and meconium related obstruction. Esophageal atresia, necrotizing entero-colitis cases had the highest mortality rate. Conclusion: This study describes EA, NEC, Low birth weight (LBW), prematurity and caesarean delivery associated with significant number of deaths of surgical patients in NICU. Novel approaches for these conditions are required to improve the survival. JAFMC Bangladesh. Vol 15, No 1 (June) 2020: 26-28

scholarly journals Demographic and Clinical Factors Associated With the Appropriate Target Thyroid-Stimulating Hormone Values in Patients With Primary Hypothyroidism Treated With Levothyroxine

2016 ◽  
Vol 6 (4) ◽  
pp. 109-115
Author(s):  
Lara Moreira Baptista de Sousa ◽  
Elisa Baranski Lamback ◽  
Thomaz Schroder Lameirinhas ◽  
Michelle Botelho Caarls ◽  
Leonardo Vieira Neto
Keyword(s):  
Thyroid Stimulating Hormone ◽  
Primary Hypothyroidism ◽  
Clinical Factors ◽  
Factors Associated ◽  
Stimulating Hormone

Predictors of thromboprophylaxis in hospitalised medical patients

2015 ◽  
Vol 113 (05) ◽  
pp. 1127-1134 ◽  
Author(s):  
David Spirk ◽  
Mathieu Nendaz ◽  
Drahomir Aujesky ◽  
Daniel Hayoz ◽  
Jürg H. Beer ◽  
...  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
High Risk ◽  
Risk Score ◽  
Low Risk ◽  
Medical Patients ◽  
Clinical Factors ◽  
Thromboembolic Risk ◽  
Factors Associated ◽  
Risk Patients

summaryBoth, underuse and overuse of thromboprophylaxis in hospitalised medical patients is common. We aimed to explore clinical factors associated with the use of pharmacological or mechanical thromboprophylaxis in acutely ill medical patients at high (Geneva Risk Score ≥ 3 points) vs low (Geneva Risk Score < 3 points) risk of venous thromboembolism. Overall, 1,478 hospitalised medical patients from eight large Swiss hospitals were enrolled in the prospective Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE) cohort study. The study is registered on ClinicalTrials. gov, number NCT01277536. Thromboprophylaxis increased stepwise with increasing Geneva Risk Score (p< 0.001). Among the 962 high-risk patients, 366 (38 %) received no thromboprophylaxis; cancer-associated thrombocytopenia (OR 4.78, 95 % CI 2.75–8.31, p< 0.001), active bleeding on admission (OR 2.88, 95 % CI 1.69–4.92, p< 0.001), and thrombocytopenia without cancer (OR 2.54, 95 % CI 1.31–4.95, p=0.006) were independently associated with the absence of prophylaxis. The use of thromboprophylaxis declined with increasing severity of thrombocytopenia (p=0.001). Among the 516 low-risk patients, 245 (48 %) received thromboprophylaxis; none of the investigated clinical factors predicted its use. In conclusion, in acutely ill medical patients, bleeding and thrombocytopenia were the most important factors for the absence of thromboprophylaxis among highrisk patients. The use of thromboprophylaxis among low-risk patients was inconsistent, without clearly identifiable predictors, and should be addressed in further research.

scholarly journals Factores asociados a la eficacia de gol en waterpolo (Factors associated with shooting efficacy in water polo)

Retos ◽  
2015 ◽  
pp. 105-108
Author(s):  
Francisco Manuel Argudo Iturriaga ◽  
Laura Garcia Cervantes ◽  
Encarnación Ruiz Lara
Keyword(s):  
Success Rate ◽  
Associated Factors ◽  
Central Area ◽  
Male And Female ◽  
Factors Associated ◽  
Water Polo ◽  
European Water ◽  
The World ◽  
The Relationship ◽  
Shooting Distance

Resumen. El objetivo del estudio fue analizar la relación entre la eficacia de gol en waterpolo y otros factores asociados como la microsituación de juego, la distancia de lanzamiento y el ángulo de lanzamiento. La muestra se compuso de 7215 lanzamientos pertenecientes al Campeonato de Europa de waterpolo (Málaga, 2008) y al Campeonato del Mundo de waterpolo (Roma, 2009). Los datos fueron analizados mediante el software Polo Análisis Directo v.1.0. Tanto en categoría femenina como masculina, la eficacia de gol de los lanzamientos de penalti fue mayor que en el resto de lanzamientos (p <.001). En waterpolo femenino se identificó un modelo con capacidad para predecir el 63% de los goles, donde se observó mayor posibilidad de gol en los lanzamientos llevados a cabo en jugadas de desigualdad numérica (OR=2.65) y de transición (OR=2.04). En waterpolo masculino el modelo tuvo capacidad para explicar el 65% de los goles, observándose mayor posibilidad de gol en las jugadas de desigualdad numérica (OR=2.59), en las jugadas de transición (OR=2.00) y en los lanzamientos efectuados desde la zona central o frontal a la portería (OR=1.33). Extrapolando los resultados al entrenamiento, deberíamos atender a dos directrices principalmente: la precisión de los lanzamientos realizados a una distancia inferior a 5 metros en las micro-situaciones de desigualdad numérica y de transición, y la eficacia de los lanzamientos en igualdad numérica a una distancia superior a 5 metros y desde posiciones laterales.Abstract. The aim of the study was to analyze the relationship between scoring and missing a goal in water polo and other associated factors such as the game micro-situation, shooting distance and shooting angle. The sample was composed of 7215 shots from the European Water Polo Championship (Malaga, 2008) and the World Water Polo Championship (Rome, 2009). The data were analyzed with Polo Analisis Directo v.1.0 software. The goal success rate of penalty shots was greater in both male and female categories than for non-penalty shots (p < .001). A model was identified in woman’s water polo that was able to predict 63% of the goals, in which the highest possibility of goal success was observed for shots taken during man-up situations (OR = 2.65) and transitions (OR = 2.04). The model applied to male water polo was able to predict 65% of the goals, showing that the highest possibility of scoring a goal corresponded to shots taken during man-up situations (OR = 2.59), in transitions (OR = 2.00) and those thrown from a central area (OR = 1.33). Extrapolating the results to apply to training, two main guiding principles should be adhered to: the precision of shots taken from less than 5 meters during man-up and transition micro-situations; and the efficacy of shots in numeric equality situations from over 5 meters and in lateral positions.

scholarly journals Assessment of clinical characteristics and mortality-associated factors in COVID-19 Critical cases in Kuwait

2020 ◽  
Author(s):  
Mariam Ayed ◽  
Abdulwahab A. Borahmah ◽  
Anwar Yazdani ◽  
Ahmad Sultan ◽  
Ahmad Mossad ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Identification ◽  
Retrospective Cohort ◽  
Associated Factors ◽  
Clinical Characteristics ◽  
Icu Patients ◽  
Factors Associated ◽  
Predicting Factors ◽  
Infected Adult ◽  
D Dimer

Objective To assess the clinical characteristics and identify mortality-predicting factors in intensive care unit (ICU)-admitted COVID-19 confirmed patients. Methods We recruited and analyzed COVID-19 infected adult patients (age≥ 18 years) who were admitted to the ICU at Jaber AlAhmad Al Sabah Hospital, Kuwait, between 1stMarch, 2020 and 30thApril 2020. The patients were followed up to 20th May, 2020. The risk factors associated with in-hospital mortality were assessed using multiple regression analysis. Results We recruited a total of 103 ICU patients in this retrospective cohort. The median age of the patients was 53 years (Interquartile Range (IQR): 44-63 years). The fatality rate was 43.7%. Among the patients, majority were males (85.5%) and 38% patients had more than two comorbidities. Pre-existing hypertension (OR:3.2,95%CI: 1.2-8.9), moderate/severe ARDS (OR: 3.4, 95%CI: 1.1-10.8),lymphocyte counts <0.5 (OR: 6.1, 95%CI: 1.2-29.8)albumin < 22 (OR: 7.5, 95%CI: 2.1-26.2), procalcitonin >0.2 (OR: 3.8, 95%CI: 1.3-7.8), D-Dimer >1200 (OR: 5.1, 95%CI: 1.2-21.6), and the need for continuous renal replacement therapy (OR: 9.3, 95%CI: 2.4-36.2) were significantly associated with mortality. Conclusion This study describes the clinical characteristics and predictors of mortality among ICU patients. Early identification of risk factors to mortality might help in their better outcome.

scholarly journals Factors Associated With Macrophage Migration Inhibitory Factor in Neonates: a Pilot Study

2021 ◽  
Author(s):  
Ji Sook Park ◽  
Jin Su Jun ◽  
Ji-Hyun Seo ◽  
Jae Young Lim ◽  
Chan-Hoo Park ◽  
...  
Keyword(s):  
Migration Inhibitory Factor ◽  
Associated Factors ◽  
Macrophage Migration Inhibitory Factor ◽  
Inhibitory Factor ◽  
Preterm Neonates ◽  
Enzyme Linked Immunosorbent Assay ◽  
Macrophage Migration ◽  
Clinical Factors ◽  
Term Neonates ◽  
Factors Associated

Abstract Objective: The study was to conduct an investigation of associated factor with macrophage migration inhibitory factor (MIF) in neonates.Results: MIF was measured by Enzyme-linked Immunosorbent Assay (ELISA) using sera obtained from sick neonates on the median postnatal 2.0nd day. Clinical details were reviewed from medical record and grouped into preterm and near or full-term neonates based on 34 weeks of gestation at birth. Statistical analyses were performed between MIF concentration and clinical factors. In total, 77 neonates consisted of preterm (n = 42) and term neonates (n = 35) were included. The median value of plasma MIF was higher in preterm neonates (7,037.6 pg/mL, IQR: 3,285.2-12,267.4) than in the others (3,968.8 pg/mL, IQR: 2,566.4-6,995.2, P = 0.013). Among 42 preterm neonates, those with necrotizing enterocolitis (NEC) in later had higher MIF concentration (12,170.9 pg/mL, IQR: 8,353.3-23,537.7, n = 9) compared with the others without NEC (5,189.6 pg/mL, IQR: 3,220.2-9,097.9, n = 33, P = 0.016). Associated factors of higher MIF in neonates were preterm neonates and NEC.

scholarly journals Sociodemographic and clinical factors associated with cryptorchidism in live births in Brazil: a 20-year analysis

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Diego Bessa Dantas ◽  
Dionata Da Costa ◽  
Edila Andrade ◽  
Maria do Socorro Bastos ◽  
Fabiana Gomes ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Secondary Data ◽  
Geographic Region ◽  
Premature Births ◽  
Place Of Birth ◽  
Clinical Factors ◽  
Level Of Education ◽  
Live Births ◽  
Factors Associated ◽  
Socio Demographic Factors

Background: Cryptorchidism is a congenital disorder that causes an irregularity in the permanent or temporary descent of one or both testicles. In Brazil, there are no comprehensive studies describing the association of demographic, social, and clinical characteristics in relation to cryptorchidism.Objectives: This study aims to verify possible associations of clinical and sociodemographic characteristics in patients with cryptorchidism.Design and Methods: An analytical, descriptive and retrospective study was carried out based on secondary data of 5,168 live births with cryptorchidism recorded in the Live Birth Information System (SINASC), Brazil from 1999 to 2018. The socio-demographic factors analyzed were the geographic region, age, education and marital status of the mothers. The clinical factors analyzed were the duration and type of pregnancy. The place of birth was also analyzed as a secondary outcome.Results: This research analyzed all live births during the study period, in Brazil. The chance of cryptorchidism in the neonate is more common in women who become pregnant later (≥30 years of age) and with a higher level of education (≥8 years). The risk of cryptorchidism in relation to the federation units is higher in Paraíba, Pernambuco, Sergipe, São Paulo, and Santa Catarina. Regarding the clinical characteristics, the shorter pregnancies, which characterize premature births, are a risk for the appearance of cryptorchidism in the country.Conclusion: Thus, in this study, we found that sociodemographic and clinical factors have specific characteristics that predict cryptorchidism in newborns in Brazil.

scholarly journals Assessment of clinical characteristics and mortality-associated factors in COVID-19 Critical cases in Kuwait

2020 ◽  
Author(s):  
Mariam Ayed ◽  
Abdulwahab A Borahmah ◽  
Anwar Yazdani ◽  
Ahmad Sultan ◽  
Ahmad Mossad ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Identification ◽  
Retrospective Cohort ◽  
Associated Factors ◽  
Clinical Characteristics ◽  
Icu Patients ◽  
Factors Associated ◽  
Predicting Factors ◽  
Infected Adult ◽  
D Dimer

AbstractPurposeTo assess the clinical characteristics and identify mortality predicting factors in intensive care unit (ICU)-admitted COVID-19 confirmed patients.MethodsWe recruited and analyzed COVID-19 infected adult patients (age≥ 18 years) who were admitted to the ICU at Jaber AlAhmad Al Sabah Hospital,Kuwait, between 1stMarch, 2020and 30thApril 2020. The patients were followed up to 20th May, 2020. The risk factors associated with in-hospital mortality were assessed using multiple regression analysis.ResultsWe recruited a total of 103 ICU patients in this retrospective cohort. The median age of the patients was 53 years (Interquartile Range (IQR): 44-63 years). The fatality rate was 43.7%. Among the patients, majority were males (85.5%) and 38% patients had more than two comorbidities. Pre-existing hypertension (OR:3.2,95%CI: 1.2-8.9), moderate/severe ARDS (OR: 3.4, 95%CI: 1.1-10.8),lymphocyte counts <0.5 (OR: 6.1, 95%CI: 1.2-29.8)albumin < 22 (OR: 7.5, 95%CI: 2.1-26.2), procalcitonin >0.2 (OR: 3.8, 95%CI: 1.3-7.8), D-Dimer >1200 (OR: 5.1, 95%CI: 1.2-21.6), and the need forcontinuous renal replacement therapy (OR: 9.3, 95%CI: 2.4-36.2) weresignificantly associated with mortality.ConclusionThis study describes the clinical characteristics and predictors ofmortality among ICU patients. Early identification of risk factors to mortality might help in their better outcome.

Sign in / Sign up

Export Citation Format

Share Document