scholarly journals In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

Materials ◽  
2020 ◽  
Vol 13 (19) ◽  
pp. 4359
Author(s):  
Oleksandr Oleshko ◽  
Iryna Liubchak ◽  
Yevheniia Husak ◽  
Viktoriia Korniienko ◽  
Aziza Yusupova ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Ag Nanoparticles ◽  
Plasma Electrolytic Oxidation ◽  
Antibacterial Properties ◽  
Phosphate Solution ◽  
Implant Surface ◽  
Collagen Production ◽  
Dental Implant Surface ◽  
Electrolytic Oxidation ◽  
Plasma Electrolytic

Despite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium–phosphate solution. Chemical and structural properties of the surface-modified titanium were assessed using scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) and contact angle measurement. A bacterial adhesion test and cell culture biocompatibility with collagen production were performed to evaluate biological effectiveness of the Ti after the plasma electrolytic process. The NTA-based calcium–phosphate solution with Ag nanoparticles (AgNPs) can provide formation of a thick, porous plasma electrolytic oxidation (PEO) layer enriched in silver oxide. Voltage elevation leads to increased porosity and a hydrophilic nature of the newly formed ceramic coating. The silver-enriched PEO layer exhibits an effective antibacterial effect with high biocompatibility and increased collagen production that could be an effective complex strategy for dental and orthopedic implant development.

scholarly journals Acceleration of Bone Formation and Adhesion Ability on Dental Implant Surface via Plasma Electrolytic Oxidation in a Solution Containing Bone Ions

Metals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 106
Author(s):  
Mosab Kaseem ◽  
Han-Cheol Choe
Keyword(s):  
Bone Formation ◽  
Dental Implant ◽  
Plasma Electrolytic Oxidation ◽  
Adhesion Ability ◽  
Post Surgery ◽  
Dental Implant Surface ◽  
Significant Difference ◽  
Rabbit Tibia ◽  
Electrolytic Oxidation ◽  
Plasma Electrolytic

The present study examined the in vitro and in vivo bone formation and adhesion ability on the surface of a titanium dental implant made by plasma electrolytic oxidation (PEO) in electrolytes containing bioactive ions. To achieve this goal, screw-shaped fabricated Ti-6Al-4V alloy implants were processed via PEO using an electrolyte solution containing calcium (Ca), phosphorous (P), magnesium (Mg), zinc (Zn), strontium (Sr), silicon (Si), and manganese (Mn) species. The screw implants doped with bioactive elements via PEO were placed in rabbit tibia, and the results were compared to the sand-blasted Ti-6Al-4V alloy implants. At eight-week post-surgery, there was no significant difference in the values of removal torque between sand-blasted and PEO-treated implants. However, it was observed that the PEO treatment of dental implants led to the formation of more periphery bone as compared to the case of sand-blasted implants. Accordingly, the PEO-treated implants have the potential to be used as promising materials for dental applications.

scholarly journals Bio-Functional Coating on Ti6Al4V Surface Produced by Using Plasma Electrolytic Oxidation

Metals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1124
Author(s):  
Aqmar Zakaria ◽  
Hamdi Shukor ◽  
Masahiro Todoh ◽  
Kamaruzaman Jusoff
Keyword(s):  
Dental Implants ◽  
Plasma Electrolytic Oxidation ◽  
Energy Dispersive Spectrometer ◽  
Antibacterial Properties ◽  
Functional Surface ◽  
Functional Coating ◽  
Fluoridated Hydroxyapatite ◽  
Coating Surface ◽  
Electrolytic Oxidation ◽  
Plasma Electrolytic

One way to improve the biofunctionality of titanium alloys is by implementing plasma electrolytic oxidation (PEO) to incorporate bioactive elements such as fluoridated hydroxyapatite, into surface coatings of orthopaedic and dental implants. Hydroxyapatite (HAp) is known as a bioactive coating while fluorapatite (FAp) has an antibacterial effect that would enhance the bio-functionality and reduce the failure rate of orthopaedic and dental implants. The purpose of this study was to develop fluoridated hydroxyapatite as a bio-functional coating on Ti6Al4V with electrolyte containing trisodium orthophosphate, potassium hydroxide, and calcium fluoride. The coating surface and cross-section morphologies were evaluated, and the species in the electrolyte solution were found, and irregular micropores shapes were observed by field emission scanning electron microscopy (FESEM) and energy dispersive spectrometer (EDS). The phase composition of the coating surface containing TiO2 (anatase and rutile), tricalcium orthophosphate, HAp, and FAp was characterized by X-ray diffractometer (XRD). The adhesive strength of the coating was analysed by a micro-scratch test. Simulated body fluid (SBF) immersion test was performed to investigate the bioactivity of the coating. In this study, we demonstrated that the PEO technique has a good potential to develop bio-functional surface modifications that can affect the chemical composition and roughness of the coating surface. The FAp coating may provide insights for subsequent bioactive coatings while improving the antibacterial properties for orthopaedic and dental implants. Future work shall investigate the optimal amount of fluoride in the coating layer that obtains excellent results without causing adverse effects on adjacent tissue.

scholarly journals COMPARATIVE ANALYSIS OF IMMUNOLOGICAL COMPATIBILITY OF BIOACTIVE CALCIUM PHOSPHATE COATINGS ON TITANIUM AND MAGNESIUM ALLOYS

2017 ◽  
Vol 60 (2) ◽  
pp. 45
Author(s):  
Tatiana S. Zaporozhets ◽  
Tatiana P. Smolina ◽  
Anna K. Gazha ◽  
Artyom V. Puz ◽  
Sergeiy. L. Sinebryukhov ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Calcium Phosphate ◽  
Magnesium Alloys ◽  
Plasma Electrolytic Oxidation ◽  
Phosphate Coatings ◽  
Electrolytic Oxidation ◽  
Plasma Electrolytic ◽  
Peo Coatings ◽  
Calcium Phosphate Coatings ◽  
Physical And Chemical

Current strategies for developing the biomaterials suggest passive modulation of osteoinductive and osteoconductive properties of the implant surface through a change in their physical and chemical parameters. Also, the osseointegration of implant depends on the reaction of the immune system, the severity of which is determined by physical and chemical properties of the material and the morphological features of the coating. In this paper, the plasma electrolytic oxidation (PEO) method for the formation of biologically active compositional corrosion resistant calcium phosphate coatings on titanium BT1-0 and magnesium alloy MA8, designed for bone bioengineering was used. Bioactive PEO coatings were additionally treated with superdispersed polytetrafluoroethylene (SPTFE) in order to improve anti-corrosion properties. The cellular and molecular aspects of immunological compatibility of bioactive calcium phosphate coatings formed on titanium and magnesium alloys by promising technology of plasma electrolytic oxidation and intended for bone tissue bioengineering were studied. It is shown that PEO coatings formed on titanium and magnesium induce an activation of human peripheral blood leukocytes in vitro, associated with increased expression of activation of molecules of CD69, CD38, CD11b on the cell membranes while shedding L-selectin (CD62L). Influence of coating process technologies on the intensity of the activation processes was established. Contact cells with calcium-phosphate PEO coatings formed on titanium and magnesium alloys induced a less pronounced activation in comparison with the untreated implants. The minimal reaction of the cells of the innate immunity was observed at using a composite of PEO coatings with SPTFE, obtained by electrophoretic deposition. The composite coating on magnesium alloys induces response of the cells of the innate immunity, comparable with the response to the coatings on titanium alloys. On the whole, immunological characteristics of the PEO coatings on titanium BT1-0 and magnesium alloy of MA8 demonstrate possibility of development of materials and wares for implant surgery, including bioresorbable alloys on magnesium base. For citation:Zaporozhets T.S., Puz A.V., Sinebryukhov S.L., Gnedenkov S.V., Smolina T.P., Gazha A.K. Comparative analysis of immunological compatibility of bioactive calcium phosphate coatings on titanium and magnesium alloys. Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol. 2017. V. 60. N 2. P. 45-51.

scholarly journals Fabrication of a Novel Ta(Zn)O Thin Film on Titanium by Magnetron Sputtering and Plasma Electrolytic Oxidation for Cell Biocompatibilities and Antibacterial Applications

Metals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 649
Author(s):  
Heng-Li Huang ◽  
Ming-Tzu Tsai ◽  
Yin-Yu Chang ◽  
Yi-Jyun Lin ◽  
Jui-Ting Hsu
Keyword(s):  
Thin Films ◽  
Magnetron Sputtering ◽  
Cell Viability ◽  
Plasma Electrolytic Oxidation ◽  
Tantalum Oxide ◽  
Antibacterial Properties ◽  
Pure Titanium ◽  
Antibacterial Performance ◽  
Electrolytic Oxidation ◽  
Plasma Electrolytic

Pure titanium (Ti) and titanium alloys are widely used as artificial implant materials for biomedical applications. The excellent biocompatibility of Ti has been attributed to the presence of a natural or artificial surface layer of titanium dioxide. Zinc oxide and tantalum oxide thin films are recognized due to their outstanding antibacterial properties. In this study, high power impulse magnetron sputtering (HiPIMS) was used for the deposition of tantalum oxide and zinc-doped Ta(Zn)O thin films on Ti with rough and porous surface, which was pretreated by plasma electrolytic oxidation (PEO). Surface morphology, antibacterial property as well as cell biocompatibility were analyzed. The antibacterial effect was studied individually for the Gram-positive and Gram-negative bacteria Staphylococcus aureus (S. aureus) and Actinobacillus actinomycetemcomitans (A. actinomycetemcomitans). The deposited Ta (Zn)O coating was composed of amorphous tantalum oxide and crystalline ZnO. The antibacterial results on the tantalum oxide and Ta(Zn)O coated Ti indicated a significant inhibition of both S. aureus and A. actinomycetemcomitans bacteria when compared with the uncoated Ti samples. The deposited Ta(Zn)O showed the best antibacterial performance. The Ta(Zn)O coated Ti showed lower level of the cell viability in MG-63 cells compared to other groups, indicating that Zn-doped Ta(Zn)O coatings may restrict the cell viability of hard tissue-derived MG-63 cells. However, the biocompatibility tests demonstrated that the tantalum oxide and Ta(Zn)O coatings improved cell attachment and cell growth in human skin fibroblasts. The cytotoxicity was found similar between the Ta2O5 and Ta(Zn)O coated Ti. By adopting a first PEO surface modification and a subsequent HiPIMS coating deposition, we synthetized amorphous tantalum oxide and Ta(Zn)O coatings that improved titanium surface properties and morphologies, making them a good surface treatment for titanium-based implants.

A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion

2021 ◽  
Vol 123 ◽  
pp. 112030
Author(s):  
Mustafa Becerikli ◽  
Alexander Kopp ◽  
Nadja Kröger ◽  
Mariia Bodrova ◽  
Christoph Wallner ◽  
...  
Keyword(s):  
Surface Modification ◽  
Plasma Electrolytic Oxidation ◽  
Titanium Implant ◽  
Implant Surface ◽  
Electrolytic Oxidation ◽  
Plasma Electrolytic ◽  
Titanium Implant Surface
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