scholarly journals Cost-Effective Analysis of Control Strategies to Reduce the Prevalence of Cutaneous Leishmaniasis, Based on a Mathematical Model

2018 ◽  
Vol 23 (3) ◽  
pp. 38
Author(s):  
Dibyendu Biswas ◽  
Suman Dolai ◽  
Jahangir Chowdhury ◽  
Priti Roy ◽  
Ellina Grigorieva
Keyword(s):  
Mathematical Model ◽  
Cutaneous Leishmaniasis ◽  
Control Strategies ◽  
Cost Effective ◽  
Sand Fly ◽  
Effective Control ◽  
Theoretic Approach ◽  
Epidemic Disease ◽  
And Control

Leishmaniasis is a neglected tropical vector-borne epidemic disease, and its transmission is a complex process. Zoonotic transmission to humans or animals occurs through the bites of female Phlebotominae sand flies. Here, reservoir is considered as a major source of endemic pathogen pool for disease outbreak, and the role of more than one reservoir animal becomes indispensable. To study the role of the reservoir animals on disease dynamics, a mathematical model was constructed consisting of susceptible and infected populations of humans and two types of reservoir (animal) and vector populations, respectively. Our aim is to prevent the disease by applying a control theoretic approach, when more than one type of reservoir animal exists in the region. We use drugs like sodium stibogluconate and meglumine antimoniate to control the disease for humans and spray insecticide to control the sand fly population. Similarly, drugs are applied for infected reservoir animals of Types A and B. We calculated the cost-effectiveness of all possible combinations of the intervention and control policies. One of our findings is that the most cost-effective case for Leishmania control is the spray of insecticides for infected sand fly vector. Alternate strategic cases were compared to address the critical shortcomings of single strategic cases, and a range of control strategies were estimated for effective control and economical benefit of the overall control strategy. Our findings provide the most innovative techniques available for application to the successful eradication of cutaneous leishmaniasis in the future.

scholarly journals Modeling the COVID-19 Epidemic With Multi-Population and Control Strategies in the United States

2022 ◽  
Vol 9 ◽  
Author(s):  
Deshun Sun ◽  
Xiaojun Long ◽  
Jingxiang Liu
Keyword(s):  
United States ◽  
Mathematical Model ◽  
Control Strategies ◽  
The United States ◽  
Basic Reproductive Number ◽  
Effective Control ◽  
Model Parameters ◽  
Cumulative Number ◽  
And Control ◽  
Sensitive Parameters

As of January 19, 2021, the cumulative number of people infected with coronavirus disease-2019 (COVID-19) in the United States has reached 24,433,486, and the number is still rising. The outbreak of the COVID-19 epidemic has not only affected the development of the global economy but also seriously threatened the lives and health of human beings around the world. According to the transmission characteristics of COVID-19 in the population, this study established a theoretical differential equation mathematical model, estimated model parameters through epidemiological data, obtained accurate mathematical models, and adopted global sensitivity analysis methods to screen sensitive parameters that significantly affect the development of the epidemic. Based on the established precise mathematical model, we calculate the basic reproductive number of the epidemic, evaluate the transmission capacity of the COVID-19 epidemic, and predict the development trend of the epidemic. By analyzing the sensitivity of parameters and finding sensitive parameters, we can provide effective control strategies for epidemic prevention and control. After appropriate modifications, the model can also be used for mathematical modeling of epidemics in other countries or other infectious diseases.

Role of Rasayana in Prevention of COVID-19 - A Review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi
Keyword(s):  
Immune System ◽  
Respiratory System ◽  
Viral Infections ◽  
Cost Effective ◽  
The Body ◽  
Healthy Life ◽  
Vital Functions ◽  
Healthy Life Style ◽  
And Control

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.

Historiographical facts and political practice in Russia in the XVIII – beginning of the XXI centuries

2022 ◽  
Author(s):  
Г.Н. Ланской
Keyword(s):  
Control Strategies ◽  
Historical Research ◽  
Political Practice ◽  
Historical Science ◽  
Political Actors ◽  
The Past ◽  
And Control ◽  
Coordination And Control ◽  
Development And Evolution

Статья посвящена истории связи между развитием исторической науки и политической практики в России. В контексте этого развития представлены, с одной стороны, эволюция исторических исследований и их координации и, с другой стороны, трансформация подхода институциональных структур государства к выбору управленческой стратегии в руководстве работой историков. В качестве примера для исследования обозначенной проблемы выбран период с начала XVIII до начала XXI века, потому что в его рамках была сформирована практика профессиональной деятельности в сфере историографии как процесса человеческой деятельности. Особое внимание в статье адресовано к роли идеологии в формировании различных моделей связи между работой историков и политических деятелей по конструированию образа прошлого, настоящего и будущего развития российской истории. The article reveals the connection between the historical science development and evolution of political practice in Russia.In that context shown are the course of the historical research and the coordination and control strategies implemented by the state, including institutional transformations.As a subject of current research was taken the period from the XVIII – beginning of the XXI centuries, when historiography became a profession and was institutionalized.Special attention is driven to the role of ideology in adopting different models of interaction between historians and political actors, while framing the image of the past, the present and the future of Russia.

scholarly journals Thermal Management of Electrified Propulsion System for Low-Carbon Vehicles

2020 ◽  
Vol 3 (4) ◽  
pp. 299-316
Author(s):  
Bo Li ◽  
Huang Kuo ◽  
Xuehui Wang ◽  
Yiyi Chen ◽  
Yangang Wang ◽  
...  
Keyword(s):  
Thermal Management ◽  
Control Strategies ◽  
Holistic Approach ◽  
Spray Cooling ◽  
Electric Machine ◽  
Low Carbon ◽  
Liquid Cooling ◽  
Management Techniques ◽  
And Control

AbstractAn overview of current thermal challenges in transport electrification is introduced in order to underpin the research developments and trends of recent thermal management techniques. Currently, explorations of intelligent thermal management and control strategies prevail among car manufacturers in the context of climate change and global warming impacts. Therefore, major cutting-edge systematic approaches in electrified powertrain are summarized in the first place. In particular, the important role of heating, ventilation and air-condition system (HVAC) is emphasised. The trends in developing efficient HVAC system for future electrified powertrain are analysed. Then electric machine efficiency is under spotlight which could be improved by introducing new thermal management techniques and strengthening the efforts of driveline integrations. The demanded integration efforts are expected to provide better value per volume, or more power output/torque per unit with smaller form factor. Driven by demands, major thermal issues of high-power density machines are raised including the comprehensive understanding of thermal path, and multiphysics challenges are addressed whilst embedding power electronic semiconductors, non-isotropic electromagnetic materials and thermal insulation materials. Last but not least, the present review has listed several typical cooling techniques such as liquid cooling jacket, impingement/spray cooling and immersion cooling that could be applied to facilitate the development of integrated electric machine, and a mechanic-electric-thermal holistic approach is suggested at early design phase. Conclusively, a brief summary of the emerging new cooling techniques is presented and the keys to a successful integration are concluded.

scholarly journals Genetic Variations in Bionomics of Culex quinquefasciatus (Diptera: Culicidae) Mosquito Population in Minna, North Central Nigeria

2016 ◽  
Vol 8 ◽  
pp. IJIS.S32516 ◽  
Author(s):  
Azubuike C. Ukubuiwe ◽  
Israel K. Olayemi ◽  
Aisha I. Jibrin
Keyword(s):  
Culex Quinquefasciatus ◽  
Control Strategies ◽  
Preliminary Investigation ◽  
Cost Effective ◽  
Immature Stage ◽  
Effective Control ◽  
Mosquito Vector ◽  
North Central ◽  
Mosquito Vector Control ◽  
Vectorial Competence

The need to have an improved knowledge on the bioecology of Culex quinquefasciatus, a prerequisite in the development of cost-effective control strategies, has informed the present preliminary investigation to put in better perspective variations that exist in the egg rafts of the species. Freshly laid egg rafts were collected and incubated at ambient temperature in well-labeled plastic trays. The results showed overall inconsistency in all indices monitored for the egg rafts. Generally, survivorship was high for the species. All immature stage and adult parameters measured varied significantly among the egg rafts and between/within sexes of the species. Therefore, this study suggests the presence of inherent variation in the bionomics of egg rafts of C. quinquefasciatus, probably influenced by the environment and hence underscores the need for additional studies to further elucidate the roles of genetics and environment in vectorial competence of the species, in order to develop robust sustainable mosquito vector control protocols.

scholarly journals Prevention of Influenza Pandemic by Multiple Control Strategies

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Roman Ullah ◽  
Gul Zaman ◽  
Saeed Islam
Keyword(s):  
Optimal Control ◽  
Control Strategies ◽  
Influenza Pandemic ◽  
Antiviral Treatment ◽  
Cost Effective ◽  
Effective Control ◽  
Numerical Techniques ◽  
Multiple Control ◽  
Control Functions ◽  
Transmission Of Disease

We present the prevention of influenza pandemic by using multiple control functions. First, we adjust the control functions in the pandemic model, then we show the existence of the optimal control problem, and, by using both analytical and numerical techniques, we investigate cost-effective control effects for the prevention of transmission of disease. To do this, we use four control functions, the first one for increasing the effect of vaccination, the second one for the strategies to isolate infected individuals, and the last two for the antiviral treatment to control clinically infectious and hospitalization cases, respectively. We completely characterized the optimal control and compute the numerical solution of the optimality system by using an iterative method.

scholarly journals Cartography and Epidemiological Study of Leishmaniasis Disease in Sefrou Province (2007–2010), Central North of Morocco

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Fatima Zahra Talbi ◽  
Fatiha El Khayyat ◽  
Hajar El Omari ◽  
Saâd Maniar ◽  
Mouhcine Fadil ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Cutaneous Leishmaniasis ◽  
Control Strategies ◽  
Age Groups ◽  
Point Of View ◽  
Health Authorities ◽  
Epidemiological Profile ◽  
And Control ◽  
Case Number

Increasing cases of leishmaniasis disease have been reported during recent years in Sefrou Province, Central North of Morocco. This study presents the epidemiological profile of the provincial population, aims at analyzing the epidemiological profile, and in particular, spatiotemporal follow-up of all cases of leishmaniasis. It is a retrospective analysis of leishmaniasis cases recorded between 2007 and 2010. The data were analyzed by SPSS software (version 20). Over a four-year period, from 2007 to 2010, there were 62 cases of leishmaniasis, 93.12% of cases of cutaneous leishmaniasis and 6.87% of visceral leishmaniasis. The case number of leishmaniasis in the Province of Sefrou varies between 0.165% and 0.0018%. For each type of leishmaniasis, the female sex was the most affected compared to the male sex. This difference cannot be considered statistically significant (χ2 = 0.083, p value = 0.77). For cutaneous leishmaniasis, all age groups were affected with a large percentage: patients aged 0–9 years with 63.11% followed by the age group [10–19] with 24.18%. Visceral leishmaniasis mainly has affected the infant population [0–9] with 83.33%. We have not observed any association between the age classes and the leishmaniasis type (χ2 = 6.20, p value = 0.4). From a spatial point of view, the majority of cases of leishmaniasis was reported in El Menzel region (67 cases) followed by Sefrou (64 cases) and Tazouta (38 cases). There is a statistically significant relationship between the type of leishmaniasis and the studied regions (χ2 = 52; p value <0.001). The study of the epidemiological profile of leishmaniasis cases may be useful in enlightening health authorities to develop screening, treatment, and control strategies to reduce the incidence rate of the disease. Other research studies can be conducted to the dynamics of the vectors of sandflies and their ecology.

scholarly journals Estimating the Optimal Control of Zoonotic Visceral Leishmaniasis by the Use of a Mathematical Model

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Laila Massad Ribas ◽  
Vera Lucia Zaher ◽  
Helio Junji Shimozako ◽  
Eduardo Massad
Keyword(s):  
Mathematical Model ◽  
Optimal Control ◽  
Visceral Leishmaniasis ◽  
Vector Control ◽  
Control Strategy ◽  
Control Strategies ◽  
Effective Control ◽  
Alternative Control ◽  
Alternative Strategies ◽  
Zoonotic Visceral Leishmaniasis

We argue that the strategy of culling infected dogs is not the most efficient way to control zoonotic visceral leishmaniasis (ZVL) and that, in the presence of alternative control strategies with better potential results, official programs of compulsory culling adopted by some countries are inefficient and unethical. We base our arguments on a mathematical model for the study of control strategies against ZVL, which allows the comparison of the efficacies of 5, alternative strategies. We demonstrate that the culling program, previously questioned on both theoretical and practical grounds is the less effective control strategy. In addition, we show that vector control and the use of insecticide-impregnated dog collars are, by far, more efficient at reducing the prevalence of ZVL in humans.

scholarly journals Research of Jiles-Atherton Dynamic Model in Giant Magnetostrictive Actuator

2016 ◽  
Vol 2016 ◽  
pp. 1-8
Author(s):  
Yongguang Liu ◽  
Xiaohui Gao ◽  
Chunxu Chen
Keyword(s):  
Mathematical Model ◽  
Dynamic Model ◽  
Control Strategies ◽  
Structural Parameters ◽  
Hysteresis Loops ◽  
Structural Dynamic ◽  
Magnetostrictive Actuator ◽  
Output Characteristics ◽  
And Control ◽  
Minor Hysteresis Loops

Due to the existence of multicoupled nonlinear factors in the giant magnetostrictive actuator (GMA), building precise mathematical model is highly important to study GMA’s characteristics and control strategies. Minor hysteresis loops near the bias magnetic field would be often applied because of its relatively good linearity. Load, friction, and disc spring stiffness seriously affect the output characteristics of the GMA in high frequency. Therefore, the current-displacement dynamic minor loops mathematical model coupling of electric-magnetic-machine is established according to Jiles-Atherton (J-A) dynamic model of hysteresis material, GMA structural dynamic equation, Ampere loop circuit law, and nonlinear piezomagnetic equation and demonstrates its correctness and effectiveness in the experiments. Finally, some laws are achieved between key structural parameters and output characteristics of GMA, which provides important theoretical foundation for structural design.

A Control System on Soil Temperature

2014 ◽  
Vol 599-601 ◽  
pp. 673-679
Author(s):  
Shi Guo Chen ◽  
Li Hua Hu ◽  
Dong Sheng Wu ◽  
Xue Yong Chen
Keyword(s):  
Mathematical Model ◽  
Control System ◽  
Soil Temperature ◽  
Control Algorithm ◽  
Soil Ecology ◽  
Control Soil ◽  
Pid Algorithm ◽  
And Control ◽  
The Mathematical Model

The soil’s temperature plays an important role of soil ecology research. In order to gain and control soil’ temperature. A control system is proposed for soil’s temperature. And a new control algorithm which is based on the PID algorithm is designed in the control system to handle the complex change of the soil’s temperature. It does not need to know the mathematical model of soil’s temperature. At last, the control result is analyzed in this paper. The result shows that the soil’s temperature is controlled ideal by this control system which is accurate to 0.5°C.

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