scholarly journals Naturally Lignan-Rich Foods: A Dietary Tool for Health Promotion?

Molecules ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 917 ◽  
Author(s):  
Carmen Rodríguez-García ◽  
Cristina Sánchez-Quesada ◽  
Estefanía Toledo ◽  
Miguel Delgado-Rodríguez ◽  
José Gaforio
Keyword(s):  
Breast Cancer ◽  
Cardiovascular Disease ◽  
Chemical Structure ◽  
Health Benefits ◽  
Dietary Guidelines ◽  
Current Evidence ◽  
Polyphenol Content ◽  
Potential Health ◽  
Bioactive Properties ◽  
Health Promoting

Dietary guidelines universally advise adherence to plant-based diets. Plant-based foods confer considerable health benefits, partly attributable to their abundant micronutrient (e.g., polyphenol) content. Interest in polyphenols is largely focused on the contribution of their antioxidant activity to the prevention of various disorders, including cardiovascular disease and cancer. Polyphenols are classified into groups, such as stilbenes, flavonoids, phenolic acids, lignans and others. Lignans, which possess a steroid-like chemical structure and are defined as phytoestrogens, are of particular interest to researchers. Traditionally, health benefits attributed to lignans have included a lowered risk of heart disease, menopausal symptoms, osteoporosis and breast cancer. However, the intake of naturally lignan-rich foods varies with the type of diet. Consequently, based on the latest humans’ findings and gathered information on lignan-rich foods collected from Phenol Explorer database this review focuses on the potential health benefits attributable to the consumption of different diets containing naturally lignan-rich foods. Current evidence highlight the bioactive properties of lignans as human health-promoting molecules. Thus, dietary intake of lignan-rich foods could be a useful way to bolster the prevention of chronic illness, such as certain types of cancers and cardiovascular disease.

scholarly journals Health effects with consumption of the flax lignan secoisolariciresinol diglucoside

2009 ◽  
Vol 103 (7) ◽  
pp. 929-938 ◽  
Author(s):  
Jennifer L. Adolphe ◽  
Susan J. Whiting ◽  
Bernhard H. J. Juurlink ◽  
Lilian U. Thorpe ◽  
Jane Alcorn
Keyword(s):  
Health Effects ◽  
Animal Studies ◽  
Health Benefits ◽  
Current Evidence ◽  
Future Research ◽  
Supporting Evidence ◽  
Secoisolariciresinol Diglucoside ◽  
Potential Health ◽  
Positive Effects ◽  
The Metabolic Syndrome

Flaxseed is the richest source of the lignan secoisolariciresinol diglucoside (SDG). After ingestion, SDG is converted to secoisolariciresinol, which is further metabolised to the mammalian lignans enterodiol and enterolactone. A growing body of evidence suggests that SDG metabolites may provide health benefits due to their weak oestrogenic or anti-oestrogenic effects, antioxidant activity, ability to induce phase 2 proteins and/or inhibit the activity of certain enzymes, or by mechanisms yet unidentified. Human and animal studies identify the benefits of SDG consumption. SDG metabolites may protect against CVD and the metabolic syndrome by reducing lipid and glucose concentrations, lowering blood pressure, and decreasing oxidative stress and inflammation. Flax lignans may also reduce cancer risk by preventing pre-cancerous cellular changes and by reducing angiogenesis and metastasis. Thus, dietary SDG has the potential to decrease the incidence of several chronic diseases that result in significant morbidity and mortality in industrialised countries. The available literature, though, makes it difficult to clearly identify SDG health effects because of the wide variability in study methods. However, the current evidence suggests that a dose of at least 500 mg SDG/d for approximately 8 weeks is needed to observe positive effects on cardiovascular risk factors in human patients. Flaxseed and its lignan extracts appear to be safe for most adult populations, though animal studies suggest that pregnant women should limit their exposure. The present review discusses the potential health benefits of SDG in humans, with supporting evidence from animal studies, and offers suggestions for future research.

scholarly journals Isoflavonoids — an overview of their biological activities and potential health benefits

2009 ◽  
Vol 2 (4) ◽  
pp. 211-218 ◽  
Author(s):  
Eva Miadoková
Keyword(s):  
Secondary Metabolites ◽  
Skin Diseases ◽  
Biological Activities ◽  
Health Benefits ◽  
Plant Secondary Metabolites ◽  
Epidemiologic Studies ◽  
Biological Functions ◽  
Potential Health ◽  
Health Promoting

Isoflavonoids — an overview of their biological activities and potential health benefitsThere are many biological activities attributed to isoflavonoids. The majority of them could be beneficial and some of them may be detrimental, depending on specific circumstances. Isoflavonoids play an important role in human nutrition as health promoting natural chemicals. They belong to plant secondary metabolites that mediate diverse biological functions through numerous pathways. They are structurally similar to estrogens, exerting both estrogenic and antiestrogenic properties in various tissues. The results of epidemiologic studies exploring the role of isoflavonoids in human health have been inconclusive. Some studies support the notion of a protective effect of their consumption in immunomodulation, cognition, risk reduction of certain cancers, cardiovascular and skin diseases, osteoporosis and obesity, as well as relief of menopausal symptoms. Other studies failed to demonstrate any effects.

scholarly journals A Review of Procyanidin: Updates on Current Bioactivities and Potential Health Benefits

2021 ◽  
Vol 12 (5) ◽  
pp. 5918-5940
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Disease ◽  
Chronic Diseases ◽  
Metabolic Disorders ◽  
Health Benefits ◽  
Potential Health ◽  
Macrophage Activity ◽  
Cellular Effects ◽  
Current Review ◽  
Anti Inflammatory

Procyanidin is an abundant polyphenol found in nature. It is composed of flavan-3-ol units, including catechin and epicatechin. Procyanidin is a polyphenolic polymer found in abundance in grapes, cranberries, apples, tea, cocoa, and pine bark. Procyanidin possessed antioxidant, anticancer, antitumor, anti-inflammatory, immunosuppressive, and antiallergy properties and protected against chronic diseases and metabolic disorders. Consequently, procyanidin may protect against chronic diseases such as cardiovascular disease, cancer, and immune-related diseases. Procyanidin acts as an anti-inflammatory, inhibits adipogenesis, melanogenesis, oxidative stress, and enhances lipid metabolism and macrophage activity. The current review summarized the numerous potential health benefits of procyanidin. Despite recent advances, multiple questions and challenges remain regarding procyanidin’s action, biogenesis, and bioavailability mechanisms. Further investigation of procyanidin’s metabolism, genetics, and cellular effects is necessary and should be pursued.

scholarly journals Urban forest biodiversity and cardiovascular disease: Potential health benefits from California’s street trees

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0254973
Author(s):  
John J. Giacinto ◽  
G. Andrew Fricker ◽  
Matthew Ritter ◽  
Jenn Yost ◽  
Jacqueline Doremus
Keyword(s):  
Cardiovascular Disease ◽  
Heart Disease ◽  
Mortality Rate ◽  
Urban Forest ◽  
Health Benefits ◽  
Shannon Index ◽  
Tree Planting ◽  
Forest Biodiversity ◽  
Street Trees ◽  
Potential Health

Enhanced immune functioning in response to biodiversity may explain potential health benefits from exposure to green space. Using unique data on urban forest biodiversity at the zip code level for California measured from 2014 to 2019 we test whether greater diversity of street trees is associated with reduced death from cardiovascular disease. We find that urban forests with greater biodiversity measured via the Shannon Index at the genus level are associated with a lower mortality rate for heart disease and stroke. Our estimates imply that increasing the Shannon Index by one standard deviation (0.64) is associated with a decrease in the mortality rate of 21.4 per 100,000 individuals for heart disease or 13% and 7.7 per 100,000 individuals for stroke or 16%. Our estimates remain robust across several sensitivity checks. A policy simulation for tree planting in Los Angeles based on our estimates suggests that if these relationships were causal, investment in planting for a more biodiverse set of street trees would be a cost-effective way to reduce mortality related to cardiovascular disease in urban areas.

scholarly journals Potential Health Benefits of Deep Sea Water: A Review

2016 ◽  
Vol 2016 ◽  
pp. 1-18 ◽  
Author(s):  
Samihah Zura Mohd Nani ◽  
F. A. A. Majid ◽  
A. B. Jaafar ◽  
A. Mahdzir ◽  
M. N. Musa
Keyword(s):  
Cardiovascular Disease ◽  
Low Temperature ◽  
Deep Sea ◽  
Sea Water ◽  
Health Benefits ◽  
Good Source ◽  
Potential Health ◽  
Deep Sea Water ◽  
Beneficial Elements ◽  
Organic Decomposition

Deep sea water (DSW) commonly refers to a body of seawater that is pumped up from a depth of over 200 m. It is usually associated with the following characteristics: low temperature, high purity, and being rich with nutrients, namely, beneficial elements, which include magnesium, calcium, potassium, chromium, selenium, zinc, and vanadium. Less photosynthesis of plant planktons, consumption of nutrients, and organic decomposition have caused lots of nutrients to remain there. Due to this, DSW has potential to become a good source for health. Research has proven that DSW can help overcome health problems especially related to lifestyle-associated diseases such as cardiovascular disease, diabetes, obesity, cancer, and skin problems. This paper reviews the potential health benefits of DSW by referring to the findings from previous researches.

scholarly journals Dietary composition and nutrient content of the New Nordic Diet

2012 ◽  
Vol 16 (5) ◽  
pp. 777-785 ◽  
Author(s):  
Charlotte Mithril ◽  
Lars Ove Dragsted ◽  
Claus Meyer ◽  
Inge Tetens ◽  
Anja Biltoft-Jensen ◽  
...  
Keyword(s):  
Dietary Guidelines ◽  
Food Culture ◽  
Dietary Composition ◽  
Health Food ◽  
Potential Health ◽  
Nordic Diet ◽  
Health Promoting ◽  
New Nordic Diet ◽  
Dietary Components ◽  
Fish And Shellfish

AbstractObjectiveTo describe the dietary composition of the New Nordic Diet (NND) and to compare it with the Nordic Nutrition Recommendations (NNR)/Danish Food-based Dietary Guidelines (DFDG) and with the average Danish diet.DesignDietary components with clear health-promoting properties included in the DFDG were included in the NND in amounts at least equivalent to those prescribed by the DFDG. The quantities of the other dietary components in the NND were based on scientific arguments for their potential health-promoting properties together with considerations of acceptability, toxicological concerns, availability and the environment. Calculations were conducted for quantifying the dietary and nutrient composition of the NND.SettingDenmark.SubjectsNone.ResultsThe NND is characterized by a high content of fruits and vegetables (especially berries, cabbages, root vegetables and legumes), fresh herbs, potatoes, plants and mushrooms from the wild countryside, whole grains, nuts, fish and shellfish, seaweed, free-range livestock (including pigs and poultry) and game. Overall, the average daily intakes of macro- and micronutrients in the NND meet the NNR with small adjustments based on evidence of their health-promoting properties.ConclusionsThe NND is a prototype regional diet that takes palatability, health, food culture and the environment into consideration. Regionally appropriate healthy diets could be created on similar principles anywhere in the world.

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