scholarly journals Antidepressant Potential of Cinnamic Acids: Mechanisms of Action and Perspectives in Drug Development

Molecules ◽  
2019 ◽  
Vol 24 (24) ◽  
pp. 4469 ◽  
Author(s):  
Lúcio Ricardo Leite Diniz ◽  
Marilia Trindade de Santana Souza ◽  
Joice Nascimento Barboza ◽  
Reinaldo Nóbrega de Almeida ◽  
Damião Pergentino de Sousa
Keyword(s):  
Social Life ◽  
Age Groups ◽  
Antidepressant Activity ◽  
Mechanisms Of Action ◽  
Behavioral Disorder ◽  
Cinnamic Acids ◽  
Work Activities ◽  
And Performance ◽  
Different Levels

Depression is a health problem that compromises the quality of life of the world′s population. It has different levels of severity and a symptomatic profile that affects social life and performance in work activities, as well as a high number of deaths in certain age groups. In the search for new therapeutic options for the treatment of this behavioral disorder, the present review describes studies on antidepressant activity of cinnamic acids, which are natural products found in medicinal plants and foods. The description of the animal models used and the mechanisms of action of these compounds are discussed.

scholarly journals KAJIAN TATA LAYOUT DAN FASILITAS KERJA DOSEN TELKOM UNIVERSITY KASUS STUDI : RUANG KERJA DOSEN FIK TELKOM UNIVERSITY

2018 ◽  
Vol 3 (2) ◽  
pp. 77
Author(s):  
Doddy Friestya Asharsinyo
Keyword(s):  
Activity Patterns ◽  
Creative Industries ◽  
Creative Industry ◽  
Storage Space ◽  
Study Program ◽  
Work Activities ◽  
Working Space ◽  
And Performance ◽  
Scientific Fields

The quality and performance of lecturers apart from the quality of their education, are also obtained from the surrounding academic environment, which is related to the workspace environment in conducting Tridarma activities. The lecturer workspace is Tridarma's activities take place, it is also a space for lecturers to actualize themselves through their fields of expertise, science and works. The layout of the lecturers' workplaces related to scientific fields at the Faculty of Creative Industries differs from one another, due to the results of work activities, research carried out, and the resulting paperwork varies from dimension / size in the field of expertise / science. The standard of work space for lecturers in general is the same for all fields of science. This research method is carried out with a qualitative approach, starting by observing empirical facts about the working space of the lecturers in the Faculty of Creative Industries, and then explaining the existing conditions and analyzing in accordance with applicable standards. The results & findings of this study conclude that the activity patterns and layout in the Tel-U lecturer workspace at the Faculty of Creative Industry are associated with the field of knowledge of each study program have the same cubical pattern and facilities, with a centralized orientation circulation in the middle of the room, there is no no special work storage space.

scholarly journals Factors of Influence on the State of Happiness in the Contemporary Russian Society

2019 ◽  
Vol 7 (2) ◽  
pp. 9-33 ◽  
Author(s):  
Mikhail F. Chernysh
Keyword(s):  
Social Life ◽  
Age Groups ◽  
Social Situation ◽  
Russian Society ◽  
Standards Of Living ◽  
The Social ◽  
State Of Mind ◽  
Considerable Impact ◽  
Factors Of Influence

The article analyzes the level of happiness on the basis of the data provided by the RLMS study. Happiness is viewed as a subjective state of mind influenced by the social situation in which an individual finds him or herself. The level of happiness turns out to be dependent on sex and age. The latter is especially salient: young people feel happy more often than respondents in more advanced age groups. Standards of living and employment are also marked as variable that have considerable impact on the level of happiness. It appears that income influences happiness indirectly through the parameters of social environment and norms that characterize it. A respondent feels somewhat happier if his or her level of material well-bing is higher than the average. The level of respect shown by other people towards the respondent is another factor that can impact the level of happiness. The feeling of loneliness is a variable with considerable influence on other parameters of social life: the lonelier is the person, the more likely he or she would feel unhappy. The study demonstrated that the level of happiness, against expectations, depends primarily on the quality of social milieu.

scholarly journals Non-Parametrical Canonical Analysis of Quality-Related Characteristics of Eggs of Different Varieties of Native Hens Compared to Laying Lineage

Animals ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 153 ◽  
Author(s):  
Antonio González Ariza ◽  
Francisco Navas González ◽  
Ander Arando Arbulu ◽  
José León Jurado ◽  
Cecilio Barba Capote ◽  
...  
Keyword(s):  
Egg Quality ◽  
Age Groups ◽  
Individual Identification ◽  
Internal Quality ◽  
Control Group ◽  
External Quality ◽  
Shell Weight ◽  
Almost All ◽  
Different Levels

The aim of the present study is to characterize the productive capability of Utrerana and to compare the relationships among parameters determining the internal and external quality of the egg, through canonical correlation analysis. A flock of 68 Utrerana hens and a control group of Leghorn hens (n = 17) were housed individually to allow individual identification of eggs and for the assessment of egg quality characteristics. Almost all variables showed differences when both breeds were compared, except for white height, yolk diameter, yolkL* and yolk pH (p > 0.05). Only minor diameter, white height, yolkL*, yolka*, and shell weight reported significant differences between laying age groups. White height, yolk color, and almost all yolk color coordinates were significantly different (p < 0.05) for period and month. Egg and white weight reached highest significantly different levels for the fourth and fifth time that the hens laid an egg. External quality-related traits are better predictors of internal quality-related traits than vice versa, enabling the implementation of an effective noninvasive method for internal quality determination and egg classification aimed at suiting the needs of consumers.

scholarly journals Predictors of efficacy in depression prevention programmes

2003 ◽  
Vol 183 (5) ◽  
pp. 384-397 ◽  
Author(s):  
Eva Jané-Llopis ◽  
Clemens Hosman ◽  
Rachel Jenkins ◽  
Peter Anderson
Keyword(s):  
Depressive Symptoms ◽  
Research Design ◽  
Psychiatric Symptoms ◽  
Meta Analysis ◽  
Age Groups ◽  
High Quality ◽  
Prevention Programmes ◽  
Quality Of Research ◽  
Different Levels

BackgroundWorldwide, 340 million people are affected by depression, with high comorbid, social and economic costs.AimsTo identify potential predictors of effect in prevention programmes.MethodA meta-analysis was made of 69 programmes to reduce depression or depressive symptoms.ResultsThe weighted mean effect size of 0.22 was effective for different age groups and different levels of risk, and in reducing risk factors and depressive or psychiatric symptoms. Programmes with larger effect sizes were multi-component, included competence techniques, had more than eight sessions, had sessions 60–90 min long, had a high quality of research design and were delivered by a health care provider in targeted programmes. Older people benefited from social support, whereas behavioural methods were detrimental.ConclusionsAn 11% improvement in depressive symptoms can be achieved through prevention programmes. Single trial evaluations should ensure high quality of the research design and detailed reporting of results and potential predictors.

scholarly journals Clinical Aspects of Physiology Teaching for Ergotherapists

2019 ◽  
Vol 26 (4) ◽  
Author(s):  
Uliana Shalamay ◽  
Nadiia Pobigun
Keyword(s):  
Social Life ◽  
Medical Knowledge ◽  
The Body ◽  
Care Work ◽  
Educational Institutions ◽  
Clinical Aspects ◽  
Clinical Physiology ◽  
And Performance ◽  
Clinical Thinking

Ergotherapist – is the youngest specialty in medical practice of Ukraine. The aim of higher medical educational institutions is to formulate logical, clinical thinking and effective assimilation of medical knowledge to be used by ergotherapists-practitioners. One of the main tasks of an ergotherapist is to restore the body’s functions that have been lost as a result of illness or injury, and to restore a person to a full social life (self-care, work, etc.). These specialists are working to restore the sensory and motor functions of the body, to develop new skills and abilities for the person to adapt to living in society. Achievement of the goal and performance of these tasks is impossible without knowledge of physiology, which provides the basis for the study of pathophysiology, pharmacology, cardiology, physiotherapy and other clinical disciplines. It improves the quality of study and helps to better acquire theoretical material, to master the skills of clinical physiology a competent approach in the organization of Physiology teaching.

scholarly journals Daily Life Benefits and Usage Characteristics of Dynamic Arm Supports in Subjects with Neuromuscular Disorders

Sensors ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 4864
Author(s):  
Johannes Essers ◽  
Alessio Murgia ◽  
Anneliek Peters ◽  
Kenneth Meijer
Keyword(s):  
Social Life ◽  
Daily Life ◽  
Contextual Information ◽  
Neuromuscular Disorders ◽  
Activities Of Daily Life ◽  
Self Reports ◽  
Actual Use ◽  
And Performance ◽  
Over Time

Neuromuscular disorders cause progressive muscular weakness, which limits upper extremity mobility and performance during activities of daily life. Dynamic arm supports can improve mobility and quality of life. However, their use is often discontinued over time for unclear reasons. This study aimed to evaluate whether users of dynamic arm supports demonstrate and perceive quantifiable mobility benefits over a period of two months. Nine users of dynamic arm supports were included in this observational study. They had different neuromuscular disorders and collectively used four different arm supports. They were observed for three consecutive weeks during which they were equipped with a multi-sensor network of accelerometers to assess the actual use of the arm support and they were asked to provide self-reports on the perceived benefits of the devices. Benefits were experienced mainly during anti-gravity activities and the measured use did not change over time. The self-reports provided contextual information in domains such as participation to social life, in addition to the sensor system. However self-reports overestimated the actual use by up to three-fold compared to the accelerometer measures. A combination of objective and subjective methods is recommended for meaningful and quantifiable mobility benefits during activities of daily life.

scholarly journals The Effects of Age of Grafted Larvae and of Supplemental Feeding on Performance of Iranian Honey Bee Colonies (Apis Mellifera Meda)

2014 ◽  
Vol 58 (1) ◽  
pp. 113-117
Author(s):  
Ali Mahbobi ◽  
Jerzy Woyke ◽  
Saeed Abbasi ◽  
Mohammadbagher Farshineh-Adl ◽  
Ahmad Malakzadegan
Keyword(s):  
Apis Mellifera ◽  
Age Groups ◽  
Supplemental Feeding ◽  
Defense Behavior ◽  
Brood Production ◽  
Honey Production ◽  
Apis Mellifera Meda ◽  
And Performance ◽  
Bee Colonies

Abstract The performance of bee colonies greatly depends on the quality of the queens. The current research was conducted at the apiary of the Faculty of Agriculture, Zanjan University, in Zanjan, Iran. Together, 24 rearing colonies were assigned to 4 grafting larvae age groups: 1-day-old, 2-day-old, 3-day-old, and emergency queens. Two feeding groups, fed and not fed, were created. The effects of reared queens on biological characteristics and performance of honeybee colonies (Apis mellifera meda) headed by those queens were measured. Age of grafted larvae significantly influenced the results. The performance ratios of the most efficient colonies headed by queens reared from 1-day-old larvae compared with the least-efficient queens reared from 3-day-old larvae were 118% in brood production, 140% in bee population, and 154% in honey production. However, the age of grafted larvae did not affect colony defense behavior. Supplemental feeding of rearing colonies increased brood production to 111%, bee population to 116%, and honey production to 115%. A combination of the effect of age of larvae and supplemental feeding resulted in twice as much honey (12 kg) produced by colonies with queens reared from 1-day-old larvae in fed rearing colonies compared to those with queens raised from 3-day-old larvae in unfed rearing colonies.

An empirical investigation of the relationship between workload and performance

2015 ◽  
Vol 53 (10) ◽  
pp. 2377-2389 ◽  
Author(s):  
Alexander Bruggen
Keyword(s):  
Empirical Evidence ◽  
Data Set ◽  
Content Type ◽  
Capacity Decisions ◽  
Quantitative Performance ◽  
And Performance ◽  
The Relationship ◽  
Practical Implications ◽  
Different Levels

Purpose – The purpose of this paper is to examine the effect of workload on quantitative and qualitative job performance. Different levels of workload can affect performance of employees, and it is important for firms to assess the effect of this in order to improve capacity decisions. The literature is not entirely clear on the relationship and calls for further empirical evidence on that matter. Design/methodology/approach – The study uses field data from a mid-sized grocery supplier. In total, 9,210 observations of 27 employees over three years and eight months are analyzed with different statistical models. Employees all work in the same department so that it is a very homogenous data set. Findings – Results show that there is an inverted U-shape relationship between workload and performance. Output of employees increases up to a certain point after which it decreases. Similarly, the quality of performance is highest under moderate levels of workload, which provides evidence against a tradeoff between quantity and quality. Research limitations/implications – The study uses a unique set of data from one firm, which limits generalizability, but adds to an important stream of literature. Practical implications – Results show how workload has a direct effect on performance. Consequently, firms need to balance the workload in order to be able to maximize the performance of their employees. Originality/value – Despite the relevance of the topic, there is hardly any empirical evidence on the relationship between workload and performance. This study thus contributes to the management literature and provides significant evidence on an inverted U-shape between workload and quantitative performance.

scholarly journals The Q-Pass Index: A Multifactorial IMUs-Based Tool to Assess Passing Skills in Basketball

Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4601
Author(s):  
Arturo Quílez-Maimón ◽  
Francisco Javier Rojas-Ruiz ◽  
Gabriel Delgado-García ◽  
Javier Courel-Ibáñez
Keyword(s):  
Inertial Sensors ◽  
Basketball Players ◽  
Video Cameras ◽  
Different Types ◽  
Practical Tool ◽  
And Performance ◽  
Pattern Variability ◽  
Different Levels ◽  
Practical Measure

Despite being a key sport-specific characteristic in performance, there is no practical tool to assess the quality of the pass in basketball. The aim of this study is to develop a tool (the quality-pass index or Q-Pass) able to deliver a quantitative, practical measure of passing skills quality based on a combination of accuracy, execution time and pass pattern variability. Temporal, kinematics and performance parameters were analysed in five different types of passes (chest, bounce, crossover, between-the-leg and behind-the-back) using a field-based test, video cameras and body-worn inertial sensors (IMUs). Data from pass accuracy, time and angular velocity were collected and processed in a custom-built excel spreadsheet. The Q-pass index (0–100 score) resulted from the sum of the three factors. Data were collected from 16 young basketball players (age: 16 ± 2 years) with high (experienced) and low (novice) level of expertise. Reliability analyses found the Q-pass index as a reliable tool in both novice (CV from 4.3 to 9.3%) and experienced players (CV from 2.8 to 10.2%). Besides, important differences in the Q-pass index were found between players’ level (p < 0.05), with the experienced showing better scores in all passing situations: behind-the-back (ES = 1.91), bounce (ES = 0.82), between-the-legs (ES = 1.11), crossover (ES = 0.58) and chest (ES = 0.94). According to these findings, the Q-pass index was sensitive enough to identify the differences in passing skills between young players with different levels of expertise, providing a numbering score for each pass executed.

scholarly journals PARE0025 “RA - DON’T GIVE UP” - LIFE WITH RHEUMATOID ARTHRITIS FROM PATIENTS’ PERSPECTIVE

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1298.2-1298
Author(s):  
T. Sobierajski ◽  
J. Grygielska ◽  
E. Godlewska
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Social Life ◽  
Age Groups ◽  
Free Access ◽  
Small Pilot Study ◽  
Social Lives ◽  
Duration Of Disease ◽  
Questionnaire Research

Background:Rheumatoid arthritis (RA) as chronic and progressing to disability disease decreases a quality of life of every person suffering from it. Knowledge about this influence from patient perspective is important to limit burden of RA and organize appropriate care for patients.Objectives:RA has input on every area of individual and social lives. Recognition of patients’ situation in daily life, professional life, participation in treatment, taking life decision gives possibilities to better understanding of diseases and starting activities to change lives with RA. Aim of research was to learn attitudes, knowledge and experiences of people living with RA.Methods:The study was initiated by KnowPR in partnership with Polish Rheuma Federation ‘REF’. Main researcher was Tomasz Sobierajski PhD., sociologist from Warsaw University. The first stage of the study was a workshop with patients with RA organized by REF. It was brainstorming to identify main problems, appropriate understand life with RA and discussion on questionnaire. After small pilot study on questionnaire, research was made by CAWI technique. Questionnaire had been linked on professional websites, facebook, Twitter, health forums. The data had been completed during one month - January 2019.Results of survey were presented in booklet with comments. Opinions introducing results were done from persons represented patronages of project: minister of patient rights, president of Polish Society for Rheumatology, national consultant in rheumatology, directors of National Institute of Geriatrics, Rheumatology and Rehabilitation. Publication was enriched by stories of people with RA living full lives. Publication was launched during press conference and disseminated in hard copies and on-line with free access.Results:In survey took part 619 respondents with RA - mostly women (90%). The biggest group of respondents (34%) was in age 46-60 years old. Duration of disease was different – from few months to more than 40 years. More than half of respondents are suffering from RA more than 10 years. Disease influences of every life area. Only 38% of respondents participate in decision about their treatment and took it together with rheumatologist. There are different opinions about way of taking medication. There are not differences among age groups and duration of disease in this. Majority of patients suffer from pain (73%), from limited abilities (68%) and from permanent fatigue (69%) in everyday lives. Rheumatologist has the biggest confidence among patients like a source of information about disease (73%). Other health professionals have lower confidence (35-40%). Majority of respondents (68%) note his knowledge about diseases like rather good and better. Respondents didn’t connected their decision of having a child with disease how it has been before (59%). Part of respondents had to change or resign of professional work (30%). Part of them resigned from social life and hobbies before disease. In opinion of 57% of respondents RA changed totally their lives (57%).Conclusion:Results of survey was used like a tool in lobbying for accessibility in newest treatment in RA. Further recognize of quality of life in RA is needed. Interviews of focus groups and individuals are planned.References:[1]T. Sobierajski. Codzienność z reumatoidalnym zapaleniem stawów. Warszawa 2019Disclosure of Interests:None declared

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