scholarly journals Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study

Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 2114 ◽  
Author(s):  
Cristina Bouzas ◽  
Maria del Mar Bibiloni ◽  
Alicia Julibert ◽  
Miguel Ruiz-Canela ◽  
Jordi Salas-Salvadó ◽  
...  
Keyword(s):  
Physical Activity ◽  
Weight Loss ◽  
Body Weight ◽  
Mediterranean Diet ◽  
Longitudinal Research ◽  
Adult Population ◽  
Body Weight Loss ◽  
Health Study ◽  
Mediterranean Population ◽  
The Mediterranean

Background. Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives. The aim of this study was to assess the association between the adherence to the Mediterranean lifestyle (diet and exercise) and the desired body weight loss in an adult Mediterranean population with overweight. Methods. Cross-sectional analysis in 6355 participants (3268 men; 3087 women) with metabolic syndrome and BMI (Body mass index) between 27.0 and 40.0 kg/m2 (55–75 years old) from the PREDIMED-Plus trial. Desired weight loss was the percentage of weight that participants wished to lose. It was categorized into four cut-offs of this percentage (Q1: <10%, n = 1495; Q2: 10–15%, n = 1804; Q3: <15–20%, n = 1470; Q4: ≥20%, n = 1589). Diet was assessed using a validated food frequency questionnaire and a 17-item Mediterranean diet questionnaire. Physical activity was assessed by the validated Minnesota-REGICOR and the validated Spanish version of the Nurses’ Health Study questionnaire. Results. Participants reporting higher percentages of desired weight loss (Q3 and Q4) were younger, had higher real and perceived BMI and were more likely to have abdominal obesity. Desired weight loss correlated inversely to physical activity (Q1: 2106 MET min/week; Q4: 1585 MET min/week. p < 0.001) and adherence to Mediterranean diet (Q1: 8.7; Q4: 8.3. p < 0.001). Conclusions. In older Mediterranean individuals with weight excess, desired weight loss was inversely associated with Mediterranean lifestyle adherence. Deeply rooted aspects of the MedDiet remained similar across groups. Longitudinal research is advised to be able to establish causality.

scholarly journals Higher adherence to the Mediterranean Diet is associated with weight loss maintenance: the MedWeight study

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Dimitrios Poulimeneas ◽  
Katerina Zoupi ◽  
Eirini Mamalaki ◽  
Eirini Bathrellou ◽  
Costas Anastasiou ◽  
...  
Keyword(s):  
Physical Activity ◽  
Weight Loss ◽  
Mediterranean Diet ◽  
Dietary Pattern ◽  
Weight Loss Maintenance ◽  
Activity Level ◽  
Obesity Management ◽  
Maximum Weight ◽  
The Mediterranean ◽  
Current Weight

AbstractIntroductionAdherence to the Mediterranean dietary pattern has been associated with numerous health benefits in non-communicable diseases, including obesity management. However, the associations of the Mediterranean Diet with weight loss maintenance remain to be evaluated.MethodsWe analyzed data from 500 participants (61% women) of the MedWeight study. Eligible volunteers were men and women 18–65 years old, reporting an intentional weight loss of at least 10%, starting from a BMI ≥ 25 kg/m2. Based on their current weight, participants were characterized as maintainers (current weight ≤ 90% of maximum weight), or regainers (current weight > 95% of maximum weight). Socio-demographics, lifestyle measurements and weight history were recorded. Dietary intake was assessed by 2 telephone 24-hour recalls. Adherence to the Mediterranean Diet was assessed with the MedDietScore (range 0–55, greater scores showing higher adherence). Physical activity levels were assessed with the International Physical Activity Questionnaire-short form. Results are expressed as means ± SD, frequencies (%) or Odds Ratio [OR; 95%Confidence Interval].ResultsCompared to regainers (31%), maintainers were younger (31.4 ± 10.0 vs. 36.6 ± 10.8 years, p < 0.001), had lower BMI (25.7 ± 4.3 vs. 31.4 ± 5.1 kg/m2, p < 0.001), and had greater initial body weight loss (25.5 ± 8.6% vs. 18.4 ± 6.9%, p < 0.001). Sex and years of formal education were not significantly different between maintainers and regainers (p > 0.05). Being in the highest MedDietScore quintile (vs. the lowest) was associated with 91% higher odds of being a maintainer [crude OR = 1.91; 1.05–3.45]. This association remained significant after adjusting for sex, age, physical activity level (METŸminutes/week) and energy intake (kcal/day) [adjusted OR = 2.01; 1.05–3.83].DiscussionHigher adherence to the Mediterranean Diet was independently associated with 2-fold increased likelihood of weight loss maintenance. Our results highlight the favorable effects of a prudent dietary pattern in long-term obesity management, as well as novel targets for diet planning during weight loss maintenance.

scholarly journals Design and development of an instrument to measure overall lifestyle habits for epidemiological research: the Mediterranean Lifestyle (MEDLIFE) index

2014 ◽  
Vol 18 (6) ◽  
pp. 959-967 ◽  
Author(s):  
Mercedes Sotos-Prieto ◽  
Belén Moreno-Franco ◽  
Jose M Ordovás ◽  
Montse León ◽  
Jose A Casasnovas ◽  
...  
Keyword(s):  
Physical Activity ◽  
Social Interaction ◽  
Mediterranean Diet ◽  
Dietary Habits ◽  
Healthy Eating Index ◽  
Health Study ◽  
Study Cohort ◽  
Linear Regression Models ◽  
Lifestyle Habits ◽  
The Mediterranean

AbstractObjectiveTo design and develop a questionnaire that can account for an individual’s adherence to a Mediterranean lifestyle including the assessment of diet and physical activity patterns, as well as social interaction.DesignThe Mediterranean Lifestyle (MEDLIFE) index was created based on the current Spanish Mediterranean food guide pyramid. MEDLIFE is a twenty-eight-item derived index consisting of questions about food consumption (fifteen items), traditional Mediterranean dietary habits (seven items) and physical activity, rest and social interaction habits (six items). Linear regression models and Spearman rank correlation were fitted to assess content validity and internal consistency.SettingA subset of participants in the Aragon Workers’ Health Study cohort (Zaragoza, Spain) provided the data for development of MEDLIFE.SubjectsParticipants (n 988) of the Aragon Workers’ Health Study cohort in Spain.ResultsMean MEDLIFE score was 11·3 (sd 2·6; range: 0–28), and the quintile distribution of MEDLIFE score showed a significant association with each of the individual items as well as with specific nutrients and lifestyle indicators (intra-validity). We also quantified MEDLIFE correspondence with previously reported diet quality indices and found significant correlations (ρ range: 0·44–0·53; P<0·001) for the Alternate Healthy Eating Index, the Alternate Mediterranean Diet Index and Mediterranean Diet Adherence Screener.ConclusionsMEDLIFE is the first index to include an overall assessment of lifestyle habits. It is expected to be a more holistic tool to measure adherence to the Mediterranean lifestyle in epidemiological studies.

Postprandial insulin sensitivity and thermogenesis in frail elderly women

2010 ◽  
Vol 35 (4) ◽  
pp. 526-533 ◽  
Author(s):  
Eric D.B. Goulet ◽  
Zareen Khursigara ◽  
Réjeanne Gougeon ◽  
José A. Morais
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Weight Loss ◽  
Body Weight ◽  
Insulin Sensitivity ◽  
Frail Elderly ◽  
Elderly Women ◽  
Body Weight Loss ◽  
Healthy Elderly ◽  
Postprandial Insulin

The frailty syndrome is associated with inflammation, hypercortisolemia, and cardiovascular diseases, all of which are linked with insulin resistance. But whether frailty is characterized by insulin resistance is unclear, especially in the postprandial state. The prevalence of underweight with frailty is high. We wondered whether hypermetabolism associated with inflammation and hypercortisolemia could increase the thermic effect of food (TEF) and contribute to the frailty-associated body weight loss. In this study, we determined whether insulin sensitivity and TEF responses differ between frail and healthy elderly persons following a meal. Ten healthy and 13 frail elderly women were recruited and studied during the 5 h following the ingestion of a standardized liquid mixed-meal test. Areas under the curve (AUC) for glucose and insulin, and the product of AUC glucose × AUC insulin × 10−6 (PGI) were used as indices of insulin sensitivity. TEF was measured by indirect calorimetry. Following the meal, glucose and insulin AUCs and PGI were significantly higher in frail than in healthy elderly women and, except for the insulin AUC; these differences remained significant after adjustment for age, body weight, and physical activity. Physical activity, determined by questionnaire, was the single best predictor of PGI, explaining 27% of its variance. There was no difference in TEF between groups, and it did not correlate with any significant variable measured. Our results suggest that postprandial insulin resistance is higher in frail than in healthy elderly women, and TEF is similar, indicating that both processes do not contribute to the propensity for body weight loss.

scholarly journals Adherence to the Mediterranean diet in Cyprus and its relationship to multi-morbidity: an epidemiological study

2020 ◽  
pp. 1-10 ◽  
Author(s):  
Maria Kyprianidou ◽  
Demosthenes Panagiotakos ◽  
Antigoni Faka ◽  
Maria Kambanaros ◽  
Konstantinos C Makris ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mediterranean Diet ◽  
Adult Population ◽  
International Classification Of Diseases ◽  
Future Research ◽  
Beneficial Effects ◽  
Lower Tertile ◽  
Validated Questionnaire ◽  
Prevention Programmes ◽  
The Mediterranean

Abstract Objective: To examine the adherence to the Mediterranean diet in the adult general population of Cyprus and assess its relationship with multi-morbidity. Design: A representative sample of the adult population of Cyprus was selected in 2018–2019 using stratified sampling. Demographics, Mediterranean diet, smoking and physical activity, as well as the presence of chronic, clinical and mental conditions, were collected using a validated questionnaire. Diseases were classified according to the International Classification of Diseases, 10th Revision. Setting: The five government-controlled municipalities of the Republic of Cyprus. Participants: A total of 1140 Cypriot men and women over 18 years. Results: The average Mediterranean diet score was 15·5 ± 4·0 with males and residents of rural regions being more adherent to the Mediterranean diet compared with females and residents of urban regions (P < 0·05). Being in the higher tertile of adherence to the Mediterranean diet was associated with lower odds of multi-morbidity compared with the lower tertile, and this result was statistically significant even after adjusting for age, gender, smoking habits and physical activity (OR = 0·68, 95 % CI 0·46, 0·99). Conclusions: The study provides evidence of the adherence to the Mediterranean diet in Cypriot population and its association with multi-morbidity. Adherence to the Mediterranean diet was associated with lower risk of multi-morbidity. Future research would attempt to replicate such results that could add solid pieces of evidence towards meeting some criteria of causality and severity tests; hence, prevention programmes and practice guidelines in Cyprus and elsewhere should take into account those beneficial effects.

scholarly journals DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Maria Keller ◽  
Anat Yaskolka Meir ◽  
Stephan H. Bernhart ◽  
Yftach Gepner ◽  
Ilan Shelef ◽  
...  
Keyword(s):  
Physical Activity ◽  
Dna Methylation ◽  
Weight Loss ◽  
Body Weight ◽  
Lifestyle Intervention ◽  
Weight Change ◽  
Relative Weight ◽  
Body Weight Loss ◽  
Obesity Treatment ◽  
Successful Weight Loss

Abstract Background One of the major challenges in obesity treatment is to explain the high variability in the individual’s response to specific dietary and physical activity interventions. With this study, we tested the hypothesis that specific DNA methylation changes reflect individual responsiveness to lifestyle intervention and may serve as epigenetic predictors for a successful weight-loss. Methods We conducted an explorative genome-wide DNA methylation analysis in blood samples from 120 subjects (90% men, mean ± SD age = 49 ± 9 years, body mass-index (BMI) = 30.2 ± 3.3 kg/m2) from the 18-month CENTRAL randomized controlled trial who underwent either Mediterranean/low-carbohydrate or low-fat diet with or without physical activity. Results Analyses comparing male subjects with the most prominent body weight-loss (responders, mean weight change − 16%) vs. non-responders (+ 2.4%) (N = 10 each) revealed significant variation in DNA methylation of several genes including LRRC27, CRISP2, and SLFN12 (all adj. P < 1 × 10−5). Gene ontology analysis indicated that biological processes such as cell adhesion and molecular functions such as calcium ion binding could have an important role in determining the success of interventional therapies in obesity. Epigenome-wide association for relative weight-loss (%) identified 15 CpGs being negatively correlated with weight change after intervention (all combined P < 1 × 10− 4) including new and also known obesity candidates such as NUDT3 and NCOR2. A baseline DNA methylation score better predicted successful weight-loss [area under the curve (AUC) receiver operating characteristic (ROC) = 0.95–1.0] than predictors such as age and BMI (AUC ROC = 0.56). Conclusions Body weight-loss following 18-month lifestyle intervention is associated with specific methylation signatures. Moreover, methylation differences in the identified genes could serve as prognostic biomarkers to predict a successful weight-loss therapy and thus contribute to advances in patient-tailored obesity treatment.

Sa598 THE GUT MICROBIOME MODULATES BODY WEIGHT LOSS IN RESPONSE TO PHYSICAL ACTIVITY

2021 ◽  
Vol 160 (6) ◽  
pp. S-567-S-568
Author(s):  
Kai Wang ◽  
Wenjie Ma ◽  
Long H. Nguyen ◽  
Raaj S. Mehta ◽  
Dong Hang ◽  
...  
Keyword(s):  
Physical Activity ◽  
Weight Loss ◽  
Body Weight ◽  
Gut Microbiome ◽  
Body Weight Loss

scholarly journals Cooking at Home and Adherence to the Mediterranean Diet During the COVID-19 Confinement: The Experience From the Croatian COVIDiet Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Danijela Pfeifer ◽  
Josip Rešetar ◽  
Jasenka Gajdoš Kljusurić ◽  
Ines Panjkota Krbavčić ◽  
Darija Vranešić Bender ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mediterranean Diet ◽  
Eating Habits ◽  
Adult Population ◽  
Dietary Behavior ◽  
Dietary Quality ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
The Mediterranean ◽  
The Impact

Introduction: The primary aims of this study were to evaluate the changes in dietary behavior among the Croatian adult population during the COVID-19 outbreak and to explore the impact of confinement on cooking habits.Methods: The study was based on results from COVIDiet_Int cross-sectional study—a part of COVIDiet project (NCT04449731). A self-administered online questionnaire was used to assess the frequency of food consumption, eating habits, and sociodemographic information. A total number of 4,281 participants (80.5% females and 19.4% males) completed the questionnaire.Results: The Mediterranean Diet Adherence Screener (MEDAS) score before the confinement was 5.02 ± 1.97, while during the confinement, the MEDAS score increased to 5.85 ± 2.04. Participants who had higher adherence to the Mediterranean diet (MedDiet) during the confinement were mostly females (88.8%), aged between 20 and 50 years, with the highest level of education (66.3%) and normal BMI (70.6%). The majority of participants maintained their dietary behavior as it was before COVID-19 confinement, while 36.9% decreased their physical activity. Participants with higher MEDAS score were more eager to increase their physical activity. Additionally, higher median values of MEDAS score were noted for participants with body mass index values below 24.9 kg/m2 (6.0 vs. 5.0 for participants with BMI above 25 kg/m2). Participants in all residence places increased their cooking frequency during the confinement (53.8%), which was associated with an increase in vegetables, legumes, as well as fish and seafood consumption.Conclusions: According to our findings, Croatian adults exhibited medium adherence to the MedDiet during the COVID-19 confinement. The results suggest that cooking frequency could be positively associated with overall dietary quality, which is of utmost importance in these demanding times.

Influence of Physical Activity on Age-Related Weight Loss in the Elderly

2010 ◽  
Vol 7 (1) ◽  
pp. 78-86 ◽  
Author(s):  
Wendy C. Stephen ◽  
Ian Janssen
Keyword(s):  
Physical Activity ◽  
Weight Loss ◽  
Body Weight ◽  
Cardiovascular Health ◽  
Disease Status ◽  
Community Dwelling ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Age Related

Background:Little is known about the effects of physical activity on weight loss in older adults.Methods:Participants included 4512 community-dwelling older (≥65 yr) men and women from the Cardiovascular Health Study. Physical activity (PA) was determined from a questionnaire at baseline and subjects were divided into sex-specific PA quartiles. Weight was measured at baseline and annually over the 8 years of follow-up. The influence of PA on longitudinal changes in body weight was examined using mixed models while adjusting for lifestyle variables, sociodemographic characteristics, and disease status.Results:Body weight declined in a curvilinear manner over time with accelerated weight loss occurring in the final years. Over the 8 yr follow-up period, the least active PA quartile lost 2.72 kg. Weight loss was attenuated by 0.55 kg (20%, P = .057), 0.80 kg (29%, P = .05), and 0.69 kg (25%, P = .016) within the second through fourth PA quartiles. The effects of PA did not differ by gender, but increased with advancing age.Conclusion:Participation in modest amounts of PA attenuated age-related weight loss by approximately 25% with little additional benefit observed at higher PA levels. This finding adds to the growing number of health outcomes that are positively affected by PA.

Sign in / Sign up

Export Citation Format

Share Document