scholarly journals Genomics of Trypanosomatidae: Where We Stand and What Needs to Be Done?

Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1124
Author(s):  
Vyacheslav Yurchenko ◽  
Anzhelika Butenko ◽  
Alexei Y. Kostygov

Trypanosomatids are easy to cultivate and they are (in many cases) amenable to genetic manipulation. Genome sequencing has become a standard tool routinely used in the study of these flagellates. In this review, we summarize the current state of the field and our vision of what needs to be done in order to achieve a more comprehensive picture of trypanosomatid evolution. This will also help to illuminate the lineage-specific proteins and pathways, which can be used as potential targets in treating diseases caused by these parasites.

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052110005
Author(s):  
Hao Guo ◽  
Xinru Ba ◽  
Peiyou Gong ◽  
Guangzhi Wang ◽  
Heng Ma ◽  
...  

Ectopic spleen is a rare clinical malformation in which the spleen is relocated from its normal anatomical position to other parts of the abdomen. We report a rare case of abdominopelvic ectopic spleen caused by splenic ligament deficiency. A patient experienced intermittent pain in the left upper abdomen that was progressively aggravated. This was confirmed by comprehensive imaging examinations and postoperative pathology. We also performed a review of the literature on the current state of the field. Our data may help to improve the diagnosis and treatment of ectopic spleen.


The early and long-term development of promising young athletes is a decisive factor in being internationally competitive in top-level sports. Among the multitude of talent criteria suggested in the literature, motivation plays a prominent role in the area of psychological characteristics. It is recognised in practice and research as a relevant criterion for performance development across all sports. This article provides an overview of the current state of talent research in the field of motivation. First, the most common theories of motivation in competitive sports are described, then different measurement methods and their advantages and disadvantages as well as the predictive value of motivation for athletic performance are discussed. Finally, implications for practice are suggested. It can be summarised that motivation in sport is conceptualised and operationalised in different ways and that the decision for the right measurement instrument depends on the goal of the assessment. To get a comprehensive picture of an athlete’s motivational status, it is useful to assess several aspects of motivation through different methods.


2011 ◽  
Vol 21 (3) ◽  
pp. 88-95 ◽  
Author(s):  
Deryk S. Beal

We are amassing information about the role of the brain in speech production and the potential neural limitations that coincide with developmental stuttering at a fast rate. As such, it is difficult for many clinician-scientists who are interested in the neural correlates of stuttering to stay informed of the current state of the field. In this paper, I aim to inspire clinician-scientists to tackle hypothesis-driven research that is grounded in neurobiological theory. To this end, I will review the neuroanatomical structures, and their functions, which are implicated in speech production and then describe the relevant differences identified in these structures in people who stutter relative to their fluently speaking peers. I will conclude the paper with suggestions on directions of future research to facilitate the evolution of the field of neuroimaging of stuttering.


Urban Studies ◽  
2020 ◽  
pp. 004209802091010
Author(s):  
Kevin Ward ◽  
Timothy Bunnell

This critical commentary introduces the Summer Institute in Urban Studies (SIUS) in the context of the wider inter-disciplinary discussions over the future of urban studies. It outlines the context out of which the institute first took place in Manchester in 2014 and how it has evolved across four subsequent iterations, the most recent of which was held in Singapore in July 2018. We document and discuss the profile of those who have participated in the four institutes and reflect upon some of the challenges that have emerged through discussions on the current state of the field of urban studies and its various possible futures. In conclusion, this critical commentary reflects on what we have learnt from the four institutes to date as we plan for #SIUS2020.


TRAUMA ◽  
2021 ◽  
Vol 22 (3) ◽  
pp. 12-19
Author(s):  
A.N. Kosiakov ◽  
A.Ye. Loskutov ◽  
K.A. Hrebennikov ◽  
A.V. Miloserdov ◽  
Ye.M. Fedin ◽  
...  

Background. Additive technologies are increasingly making their way from university laboratories and high-tech industries into routine clinical practice and even into our everyday lives. Any enthusiast, having a PC and a 3D printer at his or her disposal, can create any physical object — from children’s toys to works of art. The presence on the market of a wide range of software pro-ducts, equipment, and consumables along with the data from mo-dern diagnostic methods, a high level of training and cooperation between doctors and engineers provide practical medicine with unprecedented opportunities. We are finally able to fully customize our treatment and diagnostic procedures: to perform precise preoperative planning; to draw up a detailed plan of the operation; to rehearse the intervention on full-scale anatomical prototypes using a standard tool; to conduct the surgery as quickly and atraumatically as possible; to minimize risks; to ensure the optimal functional result and to manufacture and install customized implants in the most difficult cases. The purpose was to draw the attention of our distinguished colleagues to the aspects of application of additive technologies in modern orthopaedic practice, to introduce them into the history and current state of medical prototyping, as well as to share technological nuances with them. Materials and methods. While writing this article, we incorporated the data of recent publications in specialized domestic and foreign periodicals, several monographs, materials from thematic conferences, the results of informal conversations with colleagues in the operating rooms, at the computer and production site, as well as our own experience (over 200 cases of prototyping). Conclusions. The availability of equipment, software, and consumables allows for the introduction of additive technology into the everyday practice of nearly every modern orthopaedic and trauma clinic.


2014 ◽  
Vol 30 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Gülru Necipoğlu

In this volume marking the thirtieth anniversary of Muqarnas, the Editor reflects on the evolution of the journal over the years. To that end, the members of the Editorial and Advisory Boards were sent a questionnaire, asking them to comment on the contributions of Muqarnas and its Supplements series to the field of Islamic art and architecture studies over the past three decades, and to provide suggestions for future directions. Their observations, thoughts, and hopes for Muqarnas have been anonymously incorporated into this essay, which, in conversation with their comments, looks back on the history of the publication and offers some possibilities for the path it might take going forward.
The goal here is neither to assess the historiography nor to examine the current state of the field thirty years after the opening essay of volume 1. Instead, the focus is on the development and impact of both Muqarnas and the Supplements series in a highly specialized field with relatively few and short-lived or sporadic journals, before turning to the successes and shortcomings of these publications, as outlined by some of the board members. 



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