scholarly journals Continuous Vital Monitoring During Sleep and Light Activity Using Carbon-Black Elastomer Sensors

Sensors ◽  
2020 ◽  
Vol 20 (6) ◽  
pp. 1583 ◽  
Author(s):  
Titus Jayarathna ◽  
Gaetano D. Gargiulo ◽  
Paul P. Breen

The comfortable, continuous monitoring of vital parameters is still a challenge. The long-term measurement of respiration and cardiovascular signals is required to diagnose cardiovascular and respiratory diseases. Similarly, sleep quality assessment and the recovery period following acute treatments require long-term vital parameter datalogging. To address these requirements, we have developed “VitalCore”, a wearable continuous vital parameter monitoring device in the form of a T-shirt targeting the uninterrupted monitoring of respiration, pulse, and actigraphy. VitalCore uses polymer-based stretchable resistive bands as the primary sensor to capture breathing and pulse patterns from chest expansion. The carbon black-impregnated polymer is implemented in a U-shaped configuration and attached to the T-shirt with “interfacing” material along with the accompanying electronics. In this paper, VitalCore is bench tested and compared to gold standard respiration and pulse measurements to verify its functionality and further to assess the quality of data captured during sleep and during light exercise (walking). We show that these polymer-based sensors could identify respiratory peaks with a sensitivity of 99.44%, precision of 96.23%, and false-negative rate of 0.557% during sleep. We also show that this T-shirt configuration allows the wearer to sleep in all sleeping positions with a negligible difference of data quality. The device was also able to capture breathing during gait with 88.9–100% accuracy in respiratory peak detection.

2020 ◽  
Author(s):  
Juqing Zhao ◽  
Pei Chen ◽  
Guangming Wan

BACKGROUND There has been an increase number of eHealth and mHealth interventions aimed to support symptoms among cancer survivors. However, patient engagement has not been guaranteed and standardized in these interventions. OBJECTIVE The objective of this review was to address how patient engagement has been defined and measured in eHealth and mHealth interventions designed to improve symptoms and quality of life for cancer patients. METHODS Searches were performed in MEDLINE, PsychINFO, Web of Science, and Google Scholar to identify eHealth and mHealth interventions designed specifically to improve symptom management for cancer patients. Definition and measurement of engagement and engagement related outcomes of each intervention were synthesized. This integrated review was conducted using Critical Interpretive Synthesis to ensure the quality of data synthesis. RESULTS A total of 792 intervention studies were identified through the searches; 10 research papers met the inclusion criteria. Most of them (6/10) were randomized trial, 2 were one group trail, 1 was qualitative design, and 1 paper used mixed method. Majority of identified papers defined patient engagement as the usage of an eHealth and mHealth intervention by using different variables (e.g., usage time, log in times, participation rate). Engagement has also been described as subjective experience about the interaction with the intervention. The measurement of engagement is in accordance with the definition of engagement and can be categorized as objective and subjective measures. Among identified papers, 5 used system usage data, 2 used self-reported questionnaire, 1 used sensor data and 3 used qualitative method. Almost all studies reported engagement at a moment to moment level, but there is a lack of measurement of engagement for the long term. CONCLUSIONS There have been calls to develop standard definition and measurement of patient engagement in eHealth and mHealth interventions. Besides, it is important to provide cancer patients with more tailored and engaging eHealth and mHealth interventions for long term engagement.


2007 ◽  
Vol 12 (1) ◽  
pp. 37-62 ◽  
Author(s):  
Paul Lambert ◽  
Kenneth Prandy ◽  
Wendy Bottero

This paper discusses long term trends in patterns of intergenerational social mobility in Britain. We argue that there is convincing empirical evidence of a small but steady linear trend towards increasing social mobility throughout the period 1800-2004. Our conclusions are based upon the construction and analysis of an extended micro-social dataset, which combines records from an historical genealogical study, with responses from 31 sample surveys conducted over the period 1963-2004. There has been much previous study of trends in social mobility, and little consensus on their nature. We argue that this dissension partly results from the very slow pace of change in mobility rates, which makes the time-frame of any comparison crucial, and raises important methodological questions about how long-term change in mobility is best measured. We highlight three methodological difficulties which arise when trying to draw conclusions over mobility trends - concerning the extent of controls for life course effects; the quality of data resources; and the measurement of stratification positions. After constructing a longitudinal dataset which attempts to confront these difficulties, our analyses provide robust evidence which challenges hitherto more popular, politicised claims of declining or unchanging mobility. By contrast, our findings suggest that Britain has moved, and continues to move, steadily towards increasing equality in the relationship between occupational attainment and parental background.


2012 ◽  
Vol 1 (1) ◽  
pp. 46-50
Author(s):  
Xiao-xia Huang ◽  
Lei Yan ◽  
Shi-wen Wang

Abstract Objective To evaluate the effectiveness of Hemorrhagic Fever with Renal Syndrome (HFRS) bivalent vaccine in field. Methods The articles on effectiveness of HFRS bivalent vaccine were retrieved from Vip Database, China Journal Full-text Database, Wanfang database, China Hospital Knowledge Database, Chinese Biomedical Literature Database, MEDLINE and ProQuest. Two persons extracted data and evaluated the quality of data together for meta-analysis. Results Seven articles were included into the analysis, and two articles were random clinical trials, five were quasi-trials. Meta-analysis showed that the overall effectiveness of HFRS bivalent vaccine was 85% (95% confidence interval: 53%-95%) within one year after vaccination, and the effectiveness in two-dose recipients and three-dose recipients was 87% (95% confidence interval: 54%-96%) and 60%, respectively; it was 96% (95% confidence interval: 78%-99%) within 2-5 years after vaccination, and the effectiveness in two-dose recipients and three-dose recipients was 95% (95% confidence interval: 19%-100%) and 96% (95% confidence interval: 70%-99%), respectively; it was 100% (only one article included) within 6-9.6 years after vaccination. The effectiveness in two-dose recipients was 88% (95% confidence interval: 62%-96%) during 1-2.5 years after vaccination, and that in three-dose recipients was 94% (95% confidence interval: 70%-99%) during 1-5 years after vaccination. Conclusions HFRS bivalent vaccine is effective in field, and there is no difference between two-dose recipients and three-dose recipients. We should do some further studies on the long-term effectiveness of HFRS bivalent vaccine and on the age of vaccine reception.


Author(s):  
Catherine Y Zhu ◽  
Ines Donangelo ◽  
Deepashree Gupta ◽  
Dalena T Nguyen ◽  
Joana E Ochoa ◽  
...  

Abstract Context Molecular testing to refine the diagnosis of cytologically indeterminate thyroid nodules has become increasingly popular, but data on long-term durability of test results and the rate of delayed operation are limited. Objective Determine the delayed rate of surgical resection in indeterminate nodules with benign/negative molecular testing and the risk of false-negative molecular test results. Design Prospective follow-up of the Gene Expression Classifier vs Targeted Next-Generation Sequencing in the Management of Indeterminate Thyroid Nodules randomized controlled trial comparing the diagnostic test performance of Afirma Gene Expression Classifier and ThyroSeq v2. Setting University of California, Los Angeles. Participants Patients who underwent thyroid biopsy with indeterminate (Bethesda III/IV) cytology (April 2016 to July 2017). Intervention Ultrasound surveillance. Main Outcome Measure False-negative rate of molecular testing. Results Of 95 indeterminate nodules with negative/benign molecular test results, 12 nodules underwent immediate resection (11 benign nodules, 1 noninvasive follicular thyroid neoplasm nodule with papillary-like nuclear features). Nonoperative management was pursued for 83 (87.4%) nodules. The median surveillance was 26.7 months. Ten nodules were resected during surveillance and malignancy was identified in 4 nodules (overall false-negative rate of 5.8%). In the 4 malignant nodules that underwent delayed operation, surgery was prompted by sonographic changes during surveillance. Conclusions The majority of indeterminate nodules with negative molecular testing have a stable clinical course over 3 years of follow-up, but our finding of a 6% false-negative rate highlights the importance of continuing sonographic surveillance. Long-term studies are needed to determine the optimal length of follow-up.


2014 ◽  
Vol 5 (1) ◽  
pp. 30-40
Author(s):  
Jochen Meyer

It is a strange paradox that the public is talking about health technology but cares more about disease technology: people address chronic diseases, people want to change unhealthy behaviors, people aim to help carers and nurses - but people hardly ever look at those who are and want to remain healthy. This is even stranger, as times of health outnumber periods of disease in most persons` lifetimes. Somewhat surprisingly, technology available today is not yet optimally suited to help staying healthy. The authors discuss challenges with respect to the adaption of health behavior models, long-term interaction, quality of data, design of devices, primary use of data, and life-long data. And the authors suggest understanding technical systems for wellbeing as navigational systems, guiding a person through life on a healthy path.


1997 ◽  
Vol 1 (3) ◽  
pp. 447-452 ◽  
Author(s):  
D. D. McNeil

Abstract. Over the last decade there has been some uncertainty over the calculation of "actual" catchment evaporation from the long-term difference between rainfall and runoff for the grassland Wye catchment at Plynlimon, compared to estimates made using the Penman formula on data from automatic weather stations. Hence, measurements of actual evaporation were made over a two month period in the late summer of 1992 using the eddy-correlation technique on a relatively flat but wetter than average site in this upland region. Although the site was rather restricted for this type of measurement, the quality of data proved typical of other eddy-correlation measurements made at more aerodynamically suitable sites. The ratio of actual evaporation to the Penman estimate on dry days in summer was 0.83. This compares with an average annual ratio, generated from the catchment data for the period 1978 to 1995, of 1.01. The catchment rainfall value has been improved recently by weighting each gauge using altitude domains.


2013 ◽  
Vol 8 (3-4) ◽  
pp. 390-398
Author(s):  
H. Sonnenberg ◽  
M. Rustler ◽  
M. Riechel ◽  
N. Caradot ◽  
P. Rouault ◽  
...  

Data play an important role in water-related research. Based on experiences in data collection and data processing in water-related research this paper proposes – both from a computer scientist's and an environmental engineer's point of view – a set of rules for data handling: Rule 1: Protect raw data; Rule 2: Save metadata; Rule 3: Use databases; Rule 4: Separate data from processing; Rule 5: Use programming; Rule 6: Avoid redundancy; Rule 7: Be transparent; Rule 8: Use standards and naming conventions. Applying these rules (i) increases the quality of data and results, (ii) allows to prepare data for long-term usage and make data accessible to different people, (iii) makes data processing transparent and results reproducible, and (iv) saves – at least in the long run – time and effort. With this contribution the authors would like to start a discussion about best data handling practices and present a first checklist of data handling and data processing for practitioners and researchers working in the water sector.


2020 ◽  
Author(s):  
Jianye Zhou ◽  
Zhongtian Bai ◽  
Xiaoping Liu ◽  
Yaqiong Guo ◽  
Nan Jiang ◽  
...  

SummaryRNA testing using RT-PCR can provide direct evidence for diagnoses of COVID-19 which has brought unexpected disasters and changes to our human society. However, the absorption of cotton swab for RNA lysates may lead to a low concentration of detectable RNA, which might be one of the main reasons for the unstable positive detecting rate. We designed and manufactured a kind of silicone swab with concave-convex structure, and further compared the effects of silicone and cotton swab on RNA extraction. Principal component analysis and Paired Wilcoxcon test suggested that a higher RNA concentration and A260/A280 would be obtained using silicone swab. The results indicated that our silicone swab had a more excellent ability to sample than the cotton swab, characterized by the higher quantity and quality of extracted RNA. Thus, we advised that the current cotton swabs need to be improved urgently in COVID-19 diagnoses and the process of “sample collection” and “sample pre-processing” must be standardized and emphasized.HighlightsThe current cotton swabs need to be improved urgently in COVID-19 screening.


2021 ◽  
Author(s):  
Tommaso Alberti ◽  
Davide Faranda

<p>While COVID-19 is rapidly propagating around the globe, the need for providing real-time forecasts of the epidemics pushes fits of dynamical and statistical models to available data beyond their capabilities. Here we focus on statistical predictions of COVID-19 infections performed by fitting asymptotic distributions to actual data. By taking as a case-study the epidemic evolution of total COVID-19 infections in Chinese provinces and Italian regions, we find that predictions are characterized by large uncertainties at the early stages of the epidemic growth. Those uncertainties significantly reduce after the epidemics peak is reached. Differences in the uncertainty of the forecasts at a regional level can be used to highlight the delay in the spread of the virus. Our results warn that long term extrapolation of epidemics counts must be handled with extreme care as they crucially depend not only on the quality of data, but also on the stage of the epidemics, due to the intrinsically non-linear nature of the underlying dynamics. These results suggest that real-time epidemiological projections should include wide uncertainty ranges and urge for the needs of compiling high-quality datasets of infections counts, including asymptomatic patients.</p><p>Alberti T. and Faranda D. (2020) <span>On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy. <em>Commun. Nonlin. Sci. Num. Sim.</em>, <strong>90</strong>, 105372.</span></p>


2021 ◽  
Author(s):  
◽  
Anastasia Paramore

This thesis explores possible improvements to the existing defect detection sys-tems used by Tata Steel Europe in South Wales. Exploring the possibilities of ac-curacy increases and further uses for in-house surface quality systems presents Tata Steel Europe with methods and considerations on how to improve their current surface defect management tools. This research considers three dif-ferent aspects of the defect management process and tests alternatives to the systems either currently used or not yet in place.The first section considers an ensemble object detection method using Gabor filters, histograms, and a random forest classifier. The algorithm was applied originally as an ensemble method and then as a case-study it was split into two combinations of the methods to determine what level of ensemble complexity was optimal. The images used were a set of various types of steel defect im-ages provided by Tata Steel Europe. The ensemble method achieved acceptable results compared to the existing systems, but the medium-complexity method was optimal regarding overall accuracy, false negative rate, and speed. The sec-ond section used a set of weld hole images which were split into three quality grades by defining characteristics of the feature. These images were used to test three different neural networks, an R-CNN version of GoogLeNet, and Faster R-CNN versions of ResNet-50 and ResNet-101. These networks were tasked with classifying the quality of weld holes in steel. Accurately detecting weld holes is vital in steel production as certain production processes require speed changes for welds. As the hole punches degrade over time, so does the quality of the weld hole. When weld holes are of poor quality, they can be missed or wrongly detected. All three networks detected the weld holes very well, but classifying the quality grade was approximately 60% accurate for both ResNets and 79% accurate for the GoogLeNet. These tests highlighted the importance of data quantity and quality, including lack of bias in data. The third section looks at how colour filters and greyscale methods can affect the images used for detection and classification. An investigation into coloured light sources has not been fully explored at Tata Steel in South Wales before. Having worked with the image data for sections one and two, it highlighted how important the quality of these images is. Steel defect samples were supplied, alongside their lab-confirmed defect label. Scans were taken of clean and oiled steel samples with different coloured filters and a variety of common greyscale methods were used to turn these images from RGB colour to greyscale images. The greyscale values of defect to clean steel were calculated for a specific region of interest on each steel sample. This value was used as a measure of contrast between clean and defect steel. The yellow filter with the Decolorize method produced the highest contrast image, higher than using no filter at all. For oiled sam-ples, using no filter with the Decolorize method produced the best contrast and the orange filter with the Decolorize method produced the best contrast out of the filtered images. The greyscale methods used had significant effect on the contrast of the image.The significance of this thesis is that it informs of the difficulties in developing surface inspection of steel defects due to several factors, such as environment and variation of defect shape, size, colour, and frequency. The work undertaken in this study has highlighted the need for a larger pilot line to further research both the capturing of the perfect image, and finding the most accurate detection and classification methods for each grade of steel.


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