scholarly journals Integration of a Dielectrophoretic Tapered Aluminum Microelectrode Array with a Flow Focusing Technique

Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 4957
Author(s):  
Naqib Fuad Abd Rashid ◽  
Revathy Deivasigamani ◽  
M. F. Mohd Razip Wee ◽  
Azrul Azlan Hamzah ◽  
Muhamad Ramdzan Buyong
Keyword(s):  
Flow Rate ◽  
Rate Ratio ◽  
Microelectrode Array ◽  
Flow Simulation ◽  
Optimization Method ◽  
Micro Milling ◽  
Flow Rate Ratio ◽  
Flow Focusing ◽  
Focusing Effect ◽  
Polystyrene Beads

We present the integration of a flow focusing microfluidic device in a dielectrophoretic application that based on a tapered aluminum microelectrode array (TAMA). The characterization and optimization method of microfluidic geometry performs the hydrodynamic flow focusing on the channel. The sample fluids are hydrodynamically focused into the region of interest (ROI) where the dielectrophoresis force (FDEP) is dominant. The device geometry is designed using 3D CAD software and fabricated using the micro-milling process combined with soft lithography using PDMS. The flow simulation is achieved using COMSOL Multiphysics 5.5 to study the effect of the flow rate ratio between the sample fluids (Q1) and the sheath fluids (Q2) toward the width of flow focusing. Five different flow rate ratios (Q1/Q2) are recorded in this experiment, which are 0.2, 0.4, 0.6, 0.8 and 1.0. The width of flow focusing is increased linearly with the flow rate ratio (Q1/Q2) for both the simulation and the experiment. At the highest flow rate ratio (Q1/Q2 = 1), the width of flow focusing is obtained at 638.66 µm and at the lowest flow rate ratio (Q1/Q2 = 0.2), the width of flow focusing is obtained at 226.03 µm. As a result, the flow focusing effect is able to reduce the dispersion of the particles in the microelectrode from 2000 µm to 226.03 µm toward the ROI. The significance of flow focusing on the separation of particles is studied using 10 and 1 µm polystyrene beads by applying a non-uniform electrical field to the TAMA at 10 VPP, 150 kHz. Ultimately, we are able to manipulate the trajectories of two different types of particles in the channel. For further validation, the focusing of 3.2 µm polystyrene beads within the dominant FDEP results in an enhanced manipulation efficiency from 20% to 80% in the ROI.

The Simulation and Experimental Analysis of Hydrodynamic Focusing Effect inside a Rectangular Microchannel

2015 ◽  
Vol 645-646 ◽  
pp. 449-454
Author(s):  
Shuai Jie Feng ◽  
Xin Qun Shi ◽  
Jing Zeng ◽  
Yan Peng ◽  
Mei Liu
Keyword(s):  
Aspect Ratio ◽  
Flow Rate ◽  
Cross Sections ◽  
Experimental Analysis ◽  
Rate Ratio ◽  
Flow Rate Ratio ◽  
Hydrodynamic Focusing ◽  
Rectangular Microchannel ◽  
Focusing Effect ◽  
Simulation Results

This paper models the hydrodynamic focusing performance of a micro-fluidic chip with rectangular cross-sections, and the relationships between the aspect ratio, flow rate ratio of sheath flows to the sample flow, and dimensions and position of the focused sample flow are obtained. The simulation results are consistent with theoretical outcomes. And preliminary experiments were carried out to prove the simulation results.

Determination of flow rate ratio for plate valve operating in two-phase medium

1989 ◽  
Vol 25 (7) ◽  
pp. 394-396
Author(s):  
V. E. Shcherba ◽  
I. S. Berezin ◽  
S. S. Danilenko ◽  
I. E. Titov ◽  
P. P. Filippov
Keyword(s):  
Flow Rate ◽  
Rate Ratio ◽  
Flow Rate Ratio ◽  
Two Phase ◽  
Plate Valve ◽  
Phase Medium

Effect of the argon/monomer flow-rate ratio on the flowability trend of PECVD-processed micropowder

2017 ◽  
Vol 328 ◽  
pp. 480-487 ◽  
Author(s):  
V.R. Giampietro ◽  
M. Gulas ◽  
P. Rudolf von Rohr
Keyword(s):  
Flow Rate ◽  
Rate Ratio ◽  
Flow Rate Ratio

Effects of Respiration and Gravity on Infradiaphragmatic Venous Flow in Normal and Fontan Patients

Circulation ◽  
2000 ◽  
Vol 102 (suppl_3) ◽  
Author(s):  
Tain-Yen Hsia ◽  
Sachin Khambadkone ◽  
Andrew N. Redington ◽  
Francesco Migliavacca ◽  
John E. Deanfield ◽  
...  
Keyword(s):  
Flow Rate ◽  
Rate Ratio ◽  
Venous Return ◽  
Fontan Circulation ◽  
Flow Rate Ratio ◽  
Venous Flow ◽  
Beneficial Effects ◽  
In Series ◽  
Expiratory Flow ◽  
Fontan Patients

Background —In the Fontan circulation, pulmonary and systemic vascular resistances are in series. The implications of this unique arrangement on infradiaphragmatic venous physiology are poorly understood. Methods and Results —We studied the effects of respiration and gravity on infradiaphragmatic venous flows in 20 normal healthy volunteers (control) and 48 Fontan patients (atriopulmonary connection [APC] n=15, total cavopulmonary connection [TCPC] n=30). Hepatic venous (HV), subhepatic inferior vena caval (IVC), and portal venous (PV) flow rates were measured with Doppler ultrasonography during inspiration and expiration in both the supine and upright positions. The inspiratory-to-expiratory flow rate ratio was calculated to reflect the effect of respiration, and the supine-to-upright flow rate ratio was calculated to assess the effect of gravity. HV flow depended heavily on inspiration in TCPC compared with both control and APC subjects (inspiratory-to-expiratory flow rate ratio 3.4, 1.7, and 1.6, respectively; P <0.0001). Normal PV flow was higher in expiration, but this effect was lost in TCPC and APC patients (inspiratory-to-expiratory flow rate ratio 0.8, 1.0, and 1.1, respectively; P =0.01). The respiratory influence on IVC flow was the same in all groups. Gravity decreased HV flow more in APC than in TCPC patients (supine-to-upright flow rate ratio 3.2 versus 2.1, respectively; P <0.04) but reduced PV flow equally in all groups. Conclusions —Gravity and respiration have important influences on infradiaphragmatic venous return in Fontan patients. Although gravity exerts a significant detrimental effect on lower body venous return, which is more marked in APC than in TCPC patients, the beneficial effects of respiration in TCPC patients are mediated primarily by an increase in HV flow. These effects may have important short- and long-term implications for the hemodynamics of the Fontan circulation.

scholarly journals Numerical and experimental investigation on the depressurization capacity of a new type of depressure-dominated jet mill bit

2020 ◽  
Vol 17 (6) ◽  
pp. 1602-1615
Author(s):  
Xu-Yue Chen ◽  
Tong Cao ◽  
Kai-An Yu ◽  
De-Li Gao ◽  
Jin Yang ◽  
...  
Keyword(s):  
Flow Rate ◽  
Rate Ratio ◽  
Area Ratio ◽  
Low Flow ◽  
Flow Rate Ratio ◽  
Cuttings Transport ◽  
Horizontal Drilling ◽  
Hole Cleaning ◽  
Bottom Hole ◽  
New Type

AbstractEfficient cuttings transport and improving rate of penetration (ROP) are two major challenges in horizontal drilling and extended reach drilling. A type of jet mill bit (JMB) may provide an opportunity to catch the two birds with one stone: not only enhancing cuttings transport efficiency but also improving ROP by depressuring at the bottom hole. In this paper, the JMB is further improved and a new type of depressure-dominated JMB is presented; meanwhile, the depressurization capacity of the depressure-dominated JMB is investigated by numerical simulation and experiment. The numerical study shows that low flow-rate ratio helps to enhance the depressurization capacity of the depressure-dominated JMB; for both depressurization and bottom hole cleaning concern, the flow-rate ratio is suggested to be set at approximately 1:1. With all other parameter values being constant, lower dimensionless nozzle-to-throat-area ratio may result in higher depressurization capacity and better bottom hole cleaning, and the optimal dimensionless nozzle-to-throat-area ratio is at approximately 0.15. Experiments also indicate that reducing the dimensionless flow-rate ratio may help to increase the depressurization capacity of the depressure-dominated JMB. This work provides drilling engineers with a promising tool to improve ROP.

Numerical Simulation of Jetting Instability in Flow Focusing Microfluidics

2014 ◽  
Vol 609-610 ◽  
pp. 630-636
Author(s):  
Hong Bo Zhang ◽  
Jian Pu Liu ◽  
Huan Xin Lai
Keyword(s):  
Numerical Simulation ◽  
Surface Tension ◽  
Rate Ratio ◽  
Silicone Oil ◽  
Flow Rate Ratio ◽  
Absolute Instability ◽  
Flow Ratio ◽  
Flow Focusing ◽  
Immiscible Liquids ◽  
Main Factor

In this paper, jetting behavior of two immiscible liquids, water as the outer liquid and silicone oil as the inner liquid in typical flow focusing microchannels were numerically studied using VOF method. At low capillary number, uniform microdroplets were obtained by the absolute instability. With the increasing of fluid flow ratio, the jet is thinner and tends to break up further away the cross junction. The results showed that the flow rate ratio is the main factor that influences the microdroplet sizes, while the frequency of microdroplets formation can be controlled mainly by the surface tension when it is in the jetting regime.

The Characteristics of CH4-Vapor Catalytic Reforming Reaction Considering CO2 and CH4 Reaction in the Micro-Chamber

2007 ◽  
Author(s):  
Jing-Yu Ran ◽  
Li-Xiang Niu ◽  
Qiang Tang ◽  
Li Zhang
Keyword(s):  
Mass Flow Rate ◽  
Mass Flow ◽  
Flow Rate ◽  
Rate Ratio ◽  
Reaction System ◽  
Conversion Ratio ◽  
Flow Rate Ratio ◽  
Ni Catalyst ◽  
Complex Reaction ◽  
Catalytic Reforming

Methane and vapor catalytic-reaction is a complex reaction system, and especially CH4/CO2 reaction has an important influence to the methane/vapor reforming reaction. In this paper, the reaction character for methane and vapor catalytic reforming reaction in the micro-chamber wall with Ni catalyst is numerically investigated. The results show that the CH4/CO2 reaction has a vital influence on reactive characteristics in the different H2O/CH4 mole ratio and the mass flow-rate. With increasing the H2O/CH4 mole ratio, the concentration of H2 and CO2 increases, the concentration of CO increases and then decreases, but if the H2O/CH4 mole ratio is more than 2.5, the result is different. The reaction efficiency will descend while the flow-rate increases. The results also display that the methane conversion ratio, the vapor conversion ratio, and the hydrogen concentrations can be up to 81.73%, 69.42%, and 4.29%, while the H2O/CH4 mole ratio, flow-rate and methane/vapor mass flow-rate ratio are 2.5, 7 g/h and 0.1 respectively.

Effect of CS2 Flow Rate on the Formation of Aligned Carbon Microcoils

2019 ◽  
Vol 947 ◽  
pp. 40-46
Author(s):  
Hyun Ji Kim ◽  
Sung Hoon Kim
Keyword(s):  
Flow Rate ◽  
Vapor Deposition ◽  
Rate Ratio ◽  
Chemical Vapor ◽  
Regular Structure ◽  
Flow Rate Ratio ◽  
Total Flow ◽  
Total Flow Rate ◽  
Flow Rates ◽  
Thermal Chemical Vapor Deposition

The formation of aligned carbon microcoils could be achieved using C2H2 as a source gas and CS2 as an incorporated additive gas under thermal chemical vapor deposition system. To elucidate the ratio of C2H2/CS2 for the formation of the aligned carbon microcoils, the CS2 flow rate was first manipulated under the identical C2H2 flow rate (500sccm) condition. The formation and the alignment of carbon microcoils could be only achieved under the ratio of C2H2/CS2 = 33.3 condition, namely the flow rates of CS2 = 15sccm and C2H2= 500sccm. The total flow rate of the used gases was varied under the identical C2H2/CS2 flow rate ratio (33.3) condition. The C2H2 flow rate was manipulated under the identical CS2 flow rate (15sccm) condition. It was found that the formation and the alignment of carbon microcoils could be only achieved under the condition of 15sccm of CS2 flow rate in the range of 200 ~ 500sccm of C2H2 flow rate, regardless of the flow rate ratio of C2H2/CS2 and the total flow rate. The crystal structure of the well-aligned CMCs reveals the increase in the (002) peak in XRD spectrum for the aligned carbon microcoils, indicating the existence of the more regular structure in the aligned carbon microcoils. Based on these results, the cause for the formation of the aligned carbon microcoils only in the case of the CS2 flow rate = 15sccm with the imaginary pictures for the flow rate ratio of C2H2/CS2 just above the substrate were proposed.

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