scholarly journals Time Evolution of the Skin–Electrode Interface Impedance under Different Skin Treatments

Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 5210
Author(s):  
Brendan B. Murphy ◽  
Brittany H. Scheid ◽  
Quincy Hendricks ◽  
Nicholas V. Apollo ◽  
Brian Litt ◽  
...  

A low and stable impedance at the skin–electrode interface is key to high-fidelity acquisition of biosignals, both acutely and in the long term. However, recording quality is highly variable due to the complex nature of human skin. Here, we present an experimental and modeling framework to investigate the interfacial impedance behavior, and describe how skin interventions affect its stability over time. To illustrate this approach, we report experimental measurements on the skin–electrode impedance using pre-gelled, clinical-grade electrodes in healthy human subjects recorded over 24 h following four skin treatments: (i) mechanical abrasion, (ii) chemical exfoliation, (iii) microporation, and (iv) no treatment. In the immediate post-treatment period, mechanical abrasion yields the lowest initial impedance, whereas the other treatments provide modest improvement compared to untreated skin. After 24 h, however, the impedance becomes more uniform across all groups (<20 kΩ at 10 Hz). The impedance data are fitted with an equivalent circuit model of the complete skin–electrode interface, clearly identifying skin-level versus electrode-level contributions to the overall impedance. Using this model, we systematically investigate how time and treatment affect the impedance response, and show that removal of the superficial epidermal layers is essential to achieving a low, long-term stable interface impedance.

Biosensors ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 101
Author(s):  
Yiping Huang ◽  
Yatong Song ◽  
Li Gou ◽  
Yuanwen Zou

The electrocardiogram (ECG) electrode, as a sensor, is an important part of the wearable ECG monitoring device. Natural leather is rarely used as the electrode substrate. In this paper, wearable flexible silver electrodes based on cowhide were prepared by sputtering and brush-painting. A signal generator, oscilloscope, impedance test instrument, and ECG monitor were used to build the test platform evaluating the performance of electrodes with six subjects. The lossless waveform transmission can be achieved with our electrodes. Therefore, the Pearson’s correlation coefficient calculated with input waveform and output waveform of the electrodes based on the top grain layer (GLE) and the split layer (SLE) of cowhide were 0.997 and 0.998 at 0.1 Hz respectively. The skin electrode impedance (Z) was tested, and the parameters of the equivalent circuit model of the skin electrode interface were calculated by a fitting method, indicating that the Z of the prepared electrodes was comparable with the standard gel electrode when the skin is moist enough. The signal-to-noise ratio of the ECG of the GLE and the SLE were 1.148 and 1.205 times that of the standard electrode in the standing posture, which meant the ECG measured by our electrodes was basically consistent with that measured by the standard electrode.


2022 ◽  
Author(s):  
Hao Chu ◽  
Chenxi Yang ◽  
Yantao Xing ◽  
Jianqing Li ◽  
Chengyu Liu

Abstract PurposeLong-term electrocardiogram (ECG) monitoring is an essential approach for the early diagnosis of cardiovascular diseases. Flexible dry electrodes that contains electrolyte without water could be a potential substitution of wet electrodes for long-term ECG monitoring. Therefore, this paper developes a long-term, portable ECG patch based on flexible dry electrodes, namely SEUECG-100.MethodA device consists of analog-front-end acquisition, data acquisition, and storage modules is developed and tested. An impedance test was conducted to compare the skin-electrode impedance of the flexible dry electrode and the Ag/AgCl wet electrode. The ECG signals were simutanously collected from the same subject using the SEUECG-100 and Shimmer device , which were then compared and analyzed from the perspective of ECG morphology, RR interval, and signal quality indices (SQI).ResultsThe experimental results reveal that the flexible dry electrode has the characteristics of low skin-electrode impedance. SEUECG-100 could collect high-quality ECG signals. The ECG signals collected by the two devices have a high RR interval correlation (r=0.999). SQI results show that SEUECG-100 is better than the Shimmer device in overcoming baseline drift. Long-term ECG acquisition and storage experiments show that SEUECG-100 could collect ECG signals with good stability and high reliability.ConclusionThe implementation of the proposed system design with dry electrodes could can effectively record long-term ECG monitoring with high quality in comparison to systems with wet electrodes from both impedance characteristics and signal morphology aspects.


2013 ◽  
Vol 391 ◽  
pp. 628-632
Author(s):  
Kun Da Li ◽  
Si En Zhou ◽  
Xin Miao Yang

This paper provides a modeling framework based on the system dynamics approach by which policy makers can understand the dynamic and complex nature of the policies on prioritizing public transportation within a transportation socioeconomic system. Since the government has implemented the policies on prioritizing public transportation, a framework that helps policy makers to understand the impacts of such policies is currently quite relevant. Within this framework, 6 basic subsystems: population, economic development, environmental influence, public transport development, private cars development and priority polices, focuses on the short-and long-term system behaviors.


2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Milad Alizadeh-Meghrazi ◽  
Binbin Ying ◽  
Alessandra Schlums ◽  
Emily Lam ◽  
Ladan Eskandarian ◽  
...  

Abstract Background Continuous long-term electrocardiography monitoring has been increasingly recognized for early diagnosis and management of different types of cardiovascular diseases. To find an alternative to Ag/AgCl gel electrodes that are improper for this application scenario, many efforts have been undertaken to develop novel flexible dry textile electrodes integrated into the everyday garments. With significant progresses made to address the potential issues (e.g., low signal-to-noise ratio, high skin–electrode impedance, motion artifact, and low durability), the lack of standard evaluation procedure hinders the further development of dry electrodes (mainly the design and optimization). Results A standard testing procedure and framework for skin–electrode impedance measurement is demonstrated for the development of novel dry textile electrodes. Different representative electrode materials have been screen-printed on textile substrates. To verify the performance of dry textile electrodes, impedance measurements are conducted on an agar skin model using a universal setup with consistent frequency and pressure. In addition, they are demonstrated for ECG signals acquisition, in comparison to those obtained using conventional gel electrodes. Conclusions Dry textile electrodes demonstrated similar impedance when in raised or flat structures. The tested pressure variations had an insignificant impact on electrode impedance. Looking at the effect of impedance on ECG signals, a noticeable effect on ECG signal performance metrics was not observed. Therefore, it is suggested that impedance alone is possibly not the primary indicator of signal quality. As well, the developed methods can also serve as useful guidelines for future textile dry-electrode design and testing for practical ECG monitoring applications.


2021 ◽  
Vol 13 (7) ◽  
pp. 1247
Author(s):  
Bowen Zhu ◽  
Xianhong Xie ◽  
Chuiyu Lu ◽  
Tianjie Lei ◽  
Yibing Wang ◽  
...  

Extreme hydrologic events are getting more frequent under a changing climate, and a reliable hydrological modeling framework is important to understand their mechanism. However, existing hydrological modeling frameworks are mostly constrained to a relatively coarse resolution, unrealistic input information, and insufficient evaluations, especially for the large domain, and they are, therefore, unable to address and reconstruct many of the water-related issues (e.g., flooding and drought). In this study, a 0.0625-degree (~6 km) resolution variable infiltration capacity (VIC) model developed for China from 1970 to 2016 was extensively evaluated against remote sensing and ground-based observations. A unique feature in this modeling framework is the incorporation of new remotely sensed vegetation and soil parameter dataset. To our knowledge, this constitutes the first application of VIC with such a long-term and fine resolution over a large domain, and more importantly, with a holistic system-evaluation leveraging the best available earth data. The evaluations using in-situ observations of streamflow, evapotranspiration (ET), and soil moisture (SM) indicate a great improvement. The simulations are also consistent with satellite remote sensing products of ET and SM, because the mean differences between the VIC ET and the remote sensing ET range from −2 to 2 mm/day, and the differences for SM of the top thin layer range from −2 to 3 mm. Therefore, this continental-scale hydrological modeling framework is reliable and accurate, which can be used for various applications including extreme hydrological event detections.


Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4305
Author(s):  
Takamasa Terada ◽  
Masahiro Toyoura ◽  
Takahide Sato ◽  
Xiaoyang Mao

In this work, we propose a fabric electrode with a special structure that can play the role of a noise reduction filter. Fabric electrodes made of the conductive fabric have been used for long-term ECG measurements because of their flexibility and non-invasiveness; however, due to the large impedance between the skin and the fabric electrodes, noise is easily introduced into the ECG signal. In contrast to conventional work, in which chip-type passive elements are glued to the electrode to reduce noise, the proposed electrode can obtain a noise-reduced ECG by changing the structure of fabric. Specifically, the proposed electrode was folded multiple times to form a capacitor with a capacitance of about 3 nF. It is combined with the skin-electrode impedance to form a low-pass filter. In the experiment, we made a prototype of the electrodes and measured ECG at rest and during EMG-induced exercise. As a result, the SNR values at rest and during exercise were improved about 12.02 and 10.29 , respectively, compared with the fabric electrode without special structure. In conclusion, we have shown that changing the fabric electrode structure effectively removes noise in ECG measurement.


Chemosensors ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 175
Author(s):  
Lukas Wunderlich ◽  
Peter Hausler ◽  
Susanne Märkl ◽  
Rudolf Bierl ◽  
Thomas Hirsch

The increasing popularity of nanoparticles in many applications has led to the fact that these persistent materials pollute our environment and threaten our health. An online sensor system for monitoring the presence of nanoparticles in fresh water would be highly desired. We propose a label-free sensor based on SPR imaging. The sensitivity was enhanced by a factor of about 100 by improving the detector by using a high-resolution camera. This revealed that the light source also needed to be improved by using LED excitation instead of a laser light source. As a receptor, different self-assembled monolayers have been screened. It can be seen that the nanoparticle receptor interaction is of a complex nature. The best system when taking sensitivity as well as reversibility into account is given by a dodecanethiol monolayer on the gold sensor surface. Lanthanide-doped nanoparticles, 29 nm in diameter and with a similar refractive index to the most common silica nanoparticles were detected in water down to 1.5 µg mL−1. The sensor can be fully regenerated within one hour without the need for any washing buffer. This sensing concept is expected to be easily adapted for the detection of nanoparticles of different size, shape, and composition, and upon miniaturization, suitable for long-term applications to monitor the quality of water.


2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Pablo M. De Salazar ◽  
Nicholas B. Link ◽  
Karuna Lamarca ◽  
Mauricio Santillana

Abstract Background Residents of Long-Term Care Facilities (LTCFs) represent a major share of COVID-19 deaths worldwide. Measuring the vaccine effectiveness among the most vulnerable in these settings is essential to monitor and improve mitigation strategies. Methods We evaluate the early effect of the administration of BNT162b2-mRNA vaccine to individuals older than 64 years residing in LTCFs in Catalonia, Spain. We monitor all the SARS-CoV-2 documented infections and deaths among LTCFs residents once more than 70% of them were fully vaccinated (February–March 2021). We develop a modeling framework based on the relationship between community and LTCFs transmission during the pre-vaccination period (July–December 2020). We compute the total reduction in SARS-CoV-2 documented infections and deaths among residents of LTCFs over time, as well as the reduction in the detected transmission for all the LTCFs. We compare the true observations with the counterfactual predictions. Results We estimate that once more than 70% of the LTCFs population are fully vaccinated, 74% (58–81%, 90% CI) of COVID-19 deaths and 75% (36–86%, 90% CI) of all expected documented infections among LTCFs residents are prevented. Further, detectable transmission among LTCFs residents is reduced up to 90% (76–93%, 90% CI) relative to that expected given transmission in the community. Conclusions Our findings provide evidence that high-coverage vaccination is the most effective intervention to prevent SARS-CoV-2 transmission and death among LTCFs residents. Widespread vaccination could be a feasible avenue to control the COVID-19 pandemic conditional on key factors such as vaccine escape, roll out and coverage.


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