scholarly journals Dogs as Sentinels for Flavivirus Exposure in Urban, Peri-Urban and Rural Hanoi, Vietnam

Viruses ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 507
Author(s):  
Long Pham-Thanh ◽  
Thang Nguyen-Tien ◽  
Ulf Magnusson ◽  
Vuong Bui-Nghia ◽  
Anh Bui-Ngoc ◽  
...  
Keyword(s):  
Mosquito Control ◽  
Risk Mitigation ◽  
Significant Risk ◽  
Cross Sectional Study ◽  
Cross Reactivity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Cross Sectional ◽  
Major Health ◽  
Household Level

Diseases caused by flaviviruses, including dengue fever and Japanese encephalitis, are major health problems in Vietnam. This cross-sectional study explored the feasibility of domestic dogs as sentinels to better understand risks of mosquito-borne diseases in Hanoi city. A total of 475 dogs serum samples from 221 households in six districts of Hanoi were analyzed by a competitive enzyme-linked immunosorbent assay (cELISA) for antibodies to the pr-E protein of West Nile virus and other flaviviruses due to cross-reactivity. The overall flavivirus seroprevalence in the dog population was 70.7% (95% CI = 66.4–74.8%). At the animal level, significant associations between seropositive dogs and district location, age, breed and keeping practice were determined. At the household level, the major risk factors were rural and peri-urban locations, presence of pigs, coil burning and households without mosquito-borne disease experience (p < 0.05). Mosquito control by using larvicides or electric traps could lower seropositivity, but other measures did not contribute to significant risk mitigation of flavivirus exposure in dogs. These results will support better control of mosquito-borne diseases in Hanoi, and they indicate that dogs can be used as sentinels for flavivirus exposure.

Seroprevalence of Cysticercus cellulosae and associated risk factors in free-range pigs in Kenya

2010 ◽  
Vol 84 (4) ◽  
pp. 398-403 ◽  
Author(s):  
J.M. Kagira ◽  
N. Maingi ◽  
P.W.N. Kanyari ◽  
S.M. Githigia ◽  
J.C. Ng'ang'a ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Control Measures ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Cross Sectional ◽  
Farm Level ◽  
Household Level ◽  
Free Range ◽  
Porcine Cysticercosis

AbstractPorcine cysticercosis is an emerging zoonosis with public health and economic importance. A cross-sectional study was undertaken to investigate the disease in free-range pigs on 182 smallholder farms in Busia District, Kenya. The survey households were selected using a snowballing technique. Serum samples were obtained from 284 pigs of all ages at farm level and 37 pigs from slaughter slabs in the study area. The samples were analysed for the presence of cysticercus antigen using an antigen enzyme-linked immunosorbent assay (ELISA). A structured questionnaire was administered to determine the risk factors for porcine cysticercosis on the study farms. At pig level, the total number of pigs testing positive were 11, resulting in a seroprevalence of 4% (95% confidence interval (CI): 1.9–6.2%), while the farms with a positive pig were 9% (95% CI: 3.9–14.1%). All pigs examined in the slaughter slab survey were seronegative. The distribution of possible risk factors for porcine cysticercosis that were observed at farm level was as follows: free-range pig keeping (100%), history of human taeniosis infection in a family (51%), slaughtering of pigs at home (20%), lack of meat inspection (15%) and absence of latrines (15%). The only significant (χ2 = 4.4, P = 0.034, odds ratio (OR) = 3.8) risk factor associated with the occurrence of cysticercosis was lack of latrines at household level. The study shows that porcine cysticercosis is prevalent in free-range pigs in Busia District, Kenya and thus control measures need to be instituted.

Seroprevalence of contagious bovine pleuropneumonia in cattle of Punjab, Pakistan and assessment of risk factors

2019 ◽  
Author(s):  
Ahsan Anjum ◽  
Asim Aslam ◽  
Raheela Akhtar ◽  
Tahir Yaqub ◽  
Junaid Naseer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Control Measures ◽  
Export Market ◽  
Economic Losses ◽  
Enzyme Linked Immunosorbent Assay ◽  
Contagious Bovine Pleuropneumonia ◽  
Serum Samples ◽  
Cross Sectional ◽  
Associated Risk Factors

Contagious bovine pleuropneumonia (CBPP) is an important infectious disease of respiratory system of cattle, caused by Mycoplasma mycoides subspecies mycoides. A cross sectional study was conducted in Lahore, Kasur and Jhang districts of Punjab to determine the prevalence of CBPP. A total of 560 serum samples were examined for the specific antibodies against M. mycoides subspecies mycoides, using a sandwich enzyme-linked immunosorbent assay. Associated risk factors that were evaluated include age, gender and breed. In this study, the overall seroprevalence was 8.75%. The seroprevalence of CBPP in Lahore, Kasur and Jhang were 8.26, 8.20 and 10.06%, respectively, but no significance difference (P less than 0.05) was observed. Among the assessed potential predisposing factors, gender and breed were not significantly associated with the serological status of the animal (P greater than 0.05), in which the age affected significantly the positivity to CBPP (P less than 0.05). The highest seropositivity was observed in animals of more than 7 years of age (32.08%) followed by in 4-7 years of age (8.16%) and lowest in animals of less than 4 years old (0.79%). This study confirms the presence of CBPP in the state which could be a threat to livestock export market and warrants the implementation of control measures to mitigate the economic losses associated with the disease. 

scholarly journals Seroprevalence of Antitransglutaminase and Antiendomysium Antibodies in Adult Colombian Blood Bank Donors

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Sara Paredes-Echeverri ◽  
Ayda N. Rodríguez ◽  
Wilmer A. Cárdenas ◽  
Belén Mendoza de Molano ◽  
John M. González
Keyword(s):  
Native American ◽  
Cross Sectional Study ◽  
Immunofluorescence Assay ◽  
High Reactivity ◽  
Blood Bank ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Cross Sectional ◽  
Prevalence Studies ◽  
Hla Dq2

Celiac disease (CD) is an autoimmune enteropathy induced by the ingestion of gluten from wheat, barley, and rye in genetically susceptible individuals. The global prevalence of CD is 1.4%. However, most of the prevalence studies have been conducted in Caucasian populations; few studies have been performed in Latin America. The aim of this study is to determine the seroprevalence of auto-antibodies used as markers for CD in a Colombian cohort. In this cross-sectional study, the serum samples from Colombian donors of the National Red Cross Blood Bank were collected between June and September 2017 in Bogotá, Colombia. All sera were tested for IgA antitissue transglutaminase (TTG) by enzyme-linked immunosorbent assay. Seropositive sera were tested for IgA antiendomysium (EMA) using indirect immunofluorescence assay. The ancestral genetic composition was determined in donor samples with antibody assay reactivity. Those with two seroreactive assays were typed for HLA class II DQ2 and DQ8. In total, 228 blood donors participated in the study. Among them, 113 were females (49.56%) with an average age of 31.63 years (SD ± 12.99); males had an average of 34.71 years (SD ± 13.01). Only 3 (1.31%) donors reported chronic diarrhea and nonintentional weight loss; 11 (4.82%) had a family history of CD. For the serological assays, 11 donors (4.82%) were seroreactive to IgA anti-TTG: 3 had high reactivity and 8 had low reactivity. Of those seroreactive to IgA anti-TTG, 3 (1.32%) were also seroreactive to anti-EMA, and they were typed as HLA-DQ8 or HLA-DQ2. The baseline ancestral percentage of the seroreactive donors was higher for European and Native American than for African genes. The seroprevalence for anti-TTG and anti-EMA with the presence of HLA-DQ8 and HLA-DQ2 was 1.32%. Additionally, 4.82% donor participants were reactive only for anti-TTG. Compared with other studies, our findings suggest that Colombia has a high prevalence of CD markers.

scholarly journals Seroprevalence and Associated Risk Factors of Brucellosis in Livestock and Residents of New Valley Governorate, Egypt

2020 ◽  
pp. 531-539
Author(s):  
Mohamed Said Diab ◽  
Sherif Abd Allah Zidan ◽  
Nermin Abdalla A. Hassan ◽  
Haitham Elaadli ◽  
Ahmed Mohamed Bayoumi
Keyword(s):  
Risk Factors ◽  
Raw Milk ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Human Brucellosis ◽  
Human Occupation ◽  
Serum Samples ◽  
Cross Sectional ◽  
Significant Difference ◽  
Associated Risk Factors

Brucellosis is a worldwide zoonotic disease which is now considered endemic in most parts of Egypt. A cross-sectional study was carried out from December 2018 to February 2020 to investigate the seroprevalence of brucellosis in humans and livestock residing in two regions located in New Valley Governorate, Egypt. A total of 1254 animals (673 cattle, 348 sheep, and 233 goats) and 523 human serum samples were examined for brucellosis using Rose Bengal test (RBT) and then randomly selected sera (15 from cattle, 7 from sheep, 3 from goats, and 45 from humans) were further analyzed by complement fixation test, enzyme-linked immunosorbent assay to compare and detect the sensitivity and specificity of RBT. The prevalence of brucellosis was 0% in cattle, sheep, and goats while it was 23.9% in humans using RBT. Concerning humans, there was a higher percentage of infection in EL Kharga (33.6%). The prevalence of this infection was also at a higher level among individuals aged above 40 years (28.57%). Furthermore, men (26.11%) were more inclined to be inflicted, compared to women (22.5%) with no significant difference. Considering the human occupation, abattoir workers were the most predominant group of people at risk (33.3%), followed by farmers (31.25%) and animal keepers (20.6%) while the lowest prevalence was demonstrated in the housewives where the prevalence was 18.8 %. As a result, risk factors of the age range, locality, time of infection, contact with animals, and occupational groups could significantly affect the prevalence of human brucellosis in the New Valley Governorate. In conclusion, brucellosis is an alarming problem among residents of the New Valley Governorate. Thus, reducing the prevalence in humans and animals in the region of study may include restriction of the marketing the raw milk and enhancing public health awareness.

scholarly journals Seroprevalence and risk factors for brucellosis in small ruminant flocks in Karnataka in the Southern Province of India

2021 ◽  
pp. 2855-2862
Author(s):  
Krithiga Natesan ◽  
Triveni Kalleshamurthy ◽  
Mangadevi Nookala ◽  
Chaitra Yadav ◽  
Nagalingam Mohandoss ◽  
...  
Keyword(s):  
Risk Factors ◽  
Small Ruminant ◽  
Significant Risk ◽  
Small Ruminants ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Public Health Importance ◽  
Cross Sectional ◽  
Farm Level ◽  
History Of

Background and Aim: Brucellosis is a zoonotic disease of high economic and public health importance in large and small ruminant populations worldwide. A cross-sectional study was conducted to determine the seroprevalence and risk factors of brucellosis in small ruminants in organized farms in the southern region of India. Materials and Methods: Farms exclusively rearing sheep and goats were selected based on the number of animals (small, medium, or large) and the location of the farm (urban, periurban, or rural). A total of 1499 serum samples; 1001 from sheeps and 498 from goats were sourced from six sheep and four goat farms and tested using Rose Bengal Plate and indirect Enzyme-Linked Immunosorbent Assay tests. Results: The apparent prevalence of brucellosis was higher in sheep (8.29%, 95% CI 6.7-10.1) than goats (5.82%, 95% CI 4.0-8.2). The true adjusted population level seroprevalence was also higher in sheep, at 7.7% (95% CI 6.0-9.6) than in goats, at 5.1% (95% CI 3.2-7.6). According to bivariate categorical analysis, six highly significant (p<0.001) animal- and farm-level risk factors for sheep were age, breed, number of lambings, history of abortion, rural farms, and presence of dogs on the farm. In goats, five significant risk factors were found: History of abortion, separate sheds, dogs on the farm, weekly veterinary consultation, and lack of brucellosis awareness. In a logistic regression model, abortion (OR adjusted 10.8, 95% CI 1.2-96.12), rural farms (OR adjusted 8.5, 95% CI 3.6-20.0), and absence of separate sheds on the farms (OR 1.9, 95% CI 1.1- 3.5) were found to be significant risk factors for ovine brucellosis. Conclusion: The use of complementary measures to tackle the multiple animal- and farm-level risk factors may help to reduce the disease burden in the absence of a vaccination policy for small ruminants in India.

Hepatitis A infection in patients with chronic viral liver disease: a cross-sectional study in Jahrom, Iran

2014 ◽  
Vol 143 (3) ◽  
pp. 534-539 ◽  
Author(s):  
A. AHMADI VASMEHJANI ◽  
D. JAVESHGHANI ◽  
R. BAHARLOU ◽  
M. SHAYESTEHPOUR ◽  
S. D. MOUSAVINASAB ◽  
...  
Keyword(s):  
Liver Disease ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Severe Disease ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sectional Study ◽  
Serum Samples ◽  
Cross Sectional ◽  
Chronic Hcv

SUMMARYInfection with hepatitis A virus (HAV) in patient with chronic liver disease (CLD; due to hepatitis B or hepatitis C) may cause severe disease and fulminant liver failure. This study aimed to determine the seroprevalence of HAV antibodies in patients infected with HCV or HBV in Iran (Jahrom city). A total of 159 patients with underlying CLD were recruited between September 2012 and February 2013. Serum samples were collected from each patient and tested for anti-HAV using enzyme-linked immunosorbent assay (ELISA). The overall seroprevalence of total anti-HAV was 79·2%. Patients aged 20–30 years had the lowest (28·3%) anti-HAV seropositivity and those aged >50 years had the highest (95%) seropositivity. The overall prevalence of anti-HAV in patients with chronic HCV and HBV infection was 93·7% and 77·1%, respectively. The anti-HAV seropositivity in liver cirrhosis patients was 100% compared to CLD patients. Because of low HAV immunity in younger CLD patients, vaccination against HAV should be considered.

scholarly journals Antibodies against citrullinated proteins in relation to periodontitis with or without rheumatoid arthritis: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Pit Hui Lew ◽  
Mohammad Tariqur Rahman ◽  
Syarida Hasnur Safii ◽  
Nor Adinar Baharuddin ◽  
Peter Mark Bartold ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cross Sectional Study ◽  
Causal Link ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Pocket Depth ◽  
Cross Sectional ◽  
Individual Level ◽  
Probing Pocket Depth ◽  
Citrullinated Proteins

Abstract Background Previous studies have reported conflicting findings between serum anti-citrullinated protein antibodies (ACPA) levels in rheumatoid arthritis (RA) participants with and without periodontitis (Pd). This study aimed to analyse possible correlations between serum ACPA levels and clinical parameters in Pd and RA participants. Methods Full mouth periodontal examination (probing pocket depth, clinical attachment levels, gingival bleeding index, visual plaque index) was conducted and serum samples obtained from 80 participants comprising RA, Pd, both RA and Pd (RAPd) and healthy individuals (HC). Erythrocyte sedimentation rates (ESR) and periodontal inflamed surface area (PISA) were obtained. Serum samples were analysed for ACPA quantification using enzyme-linked immunosorbent assay (ELISA). Results Median levels (IU/mL) of ACPA (interquartile range, IQR) in RAPd, RA, Pd and HC groups were 118.58(274.51), 102.02(252.89), 78.48(132.6) and 51.67(91.31) respectively. ACPA levels were significantly higher in RAPd and RA as compared to HC group (p < 0.05). However, ACPA levels of any of the groups were not correlated with any clinical periodontal and RA parameters within the respective groups. Conclusions At individual level, the amount of serum ACPA seem to have an increasing trend with the diseased condition in the order of RAPd > RA > Pd > HC. However, lack of any significant correlation between the serum ACPA levels with the clinical Pd and RA parameters warrants further studies to investigate the causal link between RA and Pd for such a trend. Further studies involving more inflammatory biomarkers might be useful to establish the causal link between Pd in the development and progression of RA or vice versa.

scholarly journals Positive association between Brucella spp seroprevalences in livestock and humans from a cross-sectional study in Garissa and Tana River Counties, Kenya

2019 ◽  
Author(s):  
S.W. Kairu-Wanyoike ◽  
D. Nyamwaya ◽  
M. Wainaina ◽  
J. Lindahl ◽  
E. Ontiri ◽  
...  
Keyword(s):  
Regression Models ◽  
Cross Sectional Study ◽  
Mixed Effects ◽  
Sectional Study ◽  
Serum Samples ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
Household Level ◽  
Tana River ◽  
Seropositive Animal

AbstractBackgroundBrucella spp. is a zoonotic bacterial agent of high public health and socio-economic importance. It infects many species of animals including wildlife, and people may get exposed through direct contact with an infected animal or consumption of raw or undercooked animal products. We implemented a linked livestock-human cross-sectional study to determine seroprevalences and risk factors of Brucella spp. in livestock and humans. We also estimated intra-cluster correlation coefficients (ICCs) for these observations at the household and village levels.MethodologyThe study was implemented in Garissa County (specifically Ijara and Sangailu areas) and Tana River (Bura and Hola) counties. A household was the unit of analysis and the sample size was derived using the standard procedures. Serum samples were obtained from selected livestock and people from randomly selected households. Humans were sampled in both counties while livestock could be sampled only in Tana River County. Samples obtained were screened for anti-Brucella IgG antibodies using ELISA kits. Data were analyzed using generalized linear mixed effects logistic regression models with the household (herd) and village being used as random effects.ResultsThe overall seroprevalences were 3.47% (95% confidence interval [CI]: 2.72 – 4.36%) and 35.81% (95% CI: 32.87 – 38.84) in livestock and humans, respectively. In livestock, older animals and those sampled in Hola had significantly higher seroprevalences that younger ones or those sampled in Bura. Herd and village random effects were significant and ICC estimates associated with these variables were 0.40 (95% CI: 0.22 – 0.60) and 0.24 (95% CI: 0.08 – 0.52), respectively. For human data, older people, males, and people who lived in pastoral areas had significantly higher Brucella spp. seroprevalences than younger ones, females or those who lived in irrigated or riverine areas. People from households that had at least one seropositive animal were 3.35 (95% CI: 1.51 – 7.41) times more likely to be seropositive compared to those that did not. Human exposures significantly clustered at the household level; the ICC estimate obtained was 0.21 (95% CI: 0.06 – 0.52).ConclusionThe presence of a seropositive animal in a household significantly increased the risk of exposure in people in that household. Brucella spp. exposures in both livestock and humans clustered significantly at the household level. This suggests that risk-based surveillance measures, guided by locations of primary cases reported, either in humans or livestock, can be used to detect Brucella spp. infections livestock or humans, respectively.Author summaryBrucellosis is an important zoonotic disease that primarily affects livestock and wildlife. In humans, the disease is characterized by prolonged fever, body aches, joint pains and weakness while in livestock, the disease causes abortions and infertility. We carried out a study in northeastern Kenya (Garissa and Tana River Counties) to identify factors that affect the distribution of the disease in people and livestock. Livestock and people from randomly selected households were recruited and serum samples obtained for screening using anti-Brucella IgG ELISA kits to determine their Brucella spp. exposure. Data obtained were analyzed using mixed effects logistic regression models. Results obtained show that human and animal Brucella spp. seroprevalences cluster at the household level. The odds of exposure in humans were at least three times higher in households that had at least one seropositive animal compared to those that did not. These results can be used to design risk-based surveillance systems where each Brucella infection identified in livestock or humans could signal potential locations of other secondary infections.

scholarly journals Serological Screening for Antibodies against SARS-CoV-2 in Dutch Shelter Cats

Viruses ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1634
Author(s):  
W. J. R. van der Leij ◽  
Els M. Broens ◽  
Jan Willem Hesselink ◽  
Nancy Schuurman ◽  
Johannes C. M. Vernooij ◽  
...  
Keyword(s):  
Neutralizing Antibodies ◽  
Large Scale ◽  
Companion Animals ◽  
Significant Risk ◽  
Cross Sectional Study ◽  
Serum Samples ◽  
Serological Screening ◽  
Cross Sectional ◽  
Animal Shelters ◽  
Second Wave

The COVID-19 pandemic raised concerns that companion animals might be infected with, and could become a reservoir of, SARS-CoV-2. As cats are popular pets and susceptible to Coronavirus, we investigated the seroprevalence of SARS-CoV-2 antibodies in shelter cats housed in Dutch animal shelters during the COVID-19 pandemic. In this large-scale cross-sectional study, serum samples of shelter cats were collected during the second wave of human COVID-19 infections in The Netherlands. Seroprevalence was determined by using an indirect protein-based ELISA validated for cats, and a Virus Neutralization Test (VNT) as confirmation. To screen for feline SARS-CoV-2 shedding, oropharyngeal and rectal swabs of cats positive for ELISA and/or VNT were analyzed using PCR tests. In 28 Dutch animal shelters, 240 shelter cats were convenience sampled. Two of these cats (0.8%; CI 95%: 0.1–3.0%) were seropositive, as evidenced by the presence of SARS-CoV-2 neutralizing antibodies. The seropositive animals tested PCR negative for SARS-CoV-2. Based on the results of this study, it is unlikely that shelter cats could be a reservoir of SARS-CoV-2 or pose a (significant) risk to public health.

scholarly journals Adenovirus Humano Tipo 36 (Ad36) se relaciona con un mejor perfil lipídico en niños Mexicanos pero no con obesidad

2021 ◽  
Vol 32 (1) ◽  
Author(s):  
Claudia Muñoz-Yañez ◽  
Ramón A González ◽  
Grisel Ballesteros ◽  
Janeth Guangorena-Gómez ◽  
Esperanza Calleros-Rincón ◽  
...  
Keyword(s):  
Infectious Agent ◽  
Cross Sectional Study ◽  
Serum Glucose ◽  
High Density Lipoproteins ◽  
Total Serum ◽  
Enzyme Linked Immunosorbent Assay ◽  
Total Serum Cholesterol ◽  
Serum Samples ◽  
Cross Sectional ◽  
Biochemical Variables

Introducción. La obesidad y su comorbilidad son de las principales causas de muerte en México, es una enfermedad multifactorial, en la que se ha visto además la participación de un agente infeccioso. Ad36 se ha asociado con obesidad, pero paradójicamente también con niveles más bajos de glucosa, colesterol y triglicéridos, sin embargo, existe controversia en diferentes poblaciones. Objetivo. Evaluar la asociación de anticuerpos antiAd36 con variables antropométricas y bioquímicas. Material y métodos. Estudio transversal en 299 niños mexicanos mestizos en edad escolar (6 a 12 años). Se obtuvieron mediciones antropométricas de altura, peso corporal, circunferencia de la cintura, grosor del pliegue cutáneo del tríceps, se calculó índice de masa corporal (IMC) y relación cintura/ altura. Las variables bioquímicas incluyeron niveles séricos de glucosa, triglicéridos, colesterol total, lipoproteínas de alta densidad y lipoproteínas de baja densidad. Se utilizó un ensayo inmunoabsorbente ligado a enzimas (ELISA) para determinar los anticuerpos contra Ad36 en las muestras de suero. Resultados. Los anticuerpos anti-Ad36 se asociaron con niveles más bajos de colesterol sérico total (β = -0.133, p = 0.021) y LDL (β = -0.166, p = 0.004), y con niveles más altos de HDL (β = 0.120, p = 0.037), pero no con obesidad. Conclusión. En resumen, la exposición previa a Ad36 se asoció con un mejor perfil lipídico en niños mexicanos, independientemente de la obesidadBackground. Obesity and its comorbidities are one of the main causes of death in Mexico; it is a multifactorial disease, in which the participation of an infectious agent has been evaluated. Ad36 is associated with obesity, but paradoxically also with lower levels of glucose, cholesterol and triglycerides; however, there is controversy in different populations. Objective. To evaluate the association of antibodies against Ad36 with anthropometric and biochemical variables. Material and Methods. Cross-sectional study in 299 Mexican-mestizo children of elementary schools (6-12 years old). Anthropometric measurements of height, body weight, waist circumference, thickness of the triceps skin fold were obtained; body mass index (BMI) and waist / height ratio were calculated. Biochemical variables included serum glucose, triglycerides, total cholesterol, high-density lipoproteins, and low-density lipoproteins. An enzyme-linked immunosorbent assay (ELISA) was used to determine antibodies against Ad36 in serum samples. Results. Anti-Ad36 antibodies were associated with lower levels of total serum cholesterol (β = -0.133, p = 0.021) and LDL (β = -0.166, p = 0.004), and with higher levels of HDL (β = 0.120, p = 0.037), but not with obesity. Conclusion. Previous exposure to Ad36 was associated with a better lipid profile in Mexican children, regardless of obesity

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