scholarly journals Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1045
Author(s):  
Hyuk-Chae Lee ◽  
Sol Jeong ◽  
Andrew Y. Cho ◽  
Kyu-Jik Kim ◽  
Jun-Young Kim ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
South Korea ◽  
Infectious Bronchitis Virus ◽  
Economic Burden ◽  
Genomic Analysis ◽  
Multiple Introductions ◽  
Infectious Bronchitis ◽  
South Korean ◽  
Phylogeographic Analysis ◽  
The Past

Infectious bronchitis virus (IBV) was first identified in the 1930s and it imposes a major economic burden on the poultry industry. In particular, GI-19 lineage has spread globally and has evolved constantly since it was first detected in China. In this study, we analyzed S1 gene sequences from 60 IBVs isolated in South Korea. Two IBV lineages, GI-15 and GI-19, were identified in South Korea. Phylogenetic analysis suggested that there were six distinct subgroups (KM91-like, K40/09-like, and QX-like I to IV) of the South Korean GI-19 IBVs. Among them, QX-type III and IV subgroups, which are phylogenetically different from those reported in South Korea in the past, accounted for more than half of the total. Moreover, the phylogeographic analysis of the QX-like subgroups indicated at least four distinct introductions of GI-19 IBVs into South Korea during 2001–2020. The efficacy of commercialized vaccines against the recently introduced QX-like subgroups should be verified, and continuous international surveillance efforts and quarantine procedures should be enhanced to prevent the incursion of viruses.

scholarly journals Prevalence and socioeconomic burden of diabetes mellitus in South Korean adults: a population-based study using administrative data

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sung-Hee Oh ◽  
Hyemin Ku ◽  
Kang Seo Park
Keyword(s):  
South Korea ◽  
Diabetic Complications ◽  
Economic Burden ◽  
Productivity Loss ◽  
Diabetic Patients ◽  
Claims Database ◽  
South Korean ◽  
Subgroup Analyses ◽  
Per Capita ◽  
Capita Cost

Abstract Background Diabetes leads to severe complications and imposes health and financial burdens on the society. However, currently existing domestic public health studies of diabetes in South Korea mainly focus on prevalence, and data on the nationwide burden of diabetes in South Korea are lacking. The study aimed to estimate the prevalence and economic burden of diabetes imposed on the South Korean society. Methods A prevalence-based cost-of-illness study was conducted using the Korean national claims database. Adult diabetic patients were defined as those aged ≥20 years with claim records containing diagnostic codes for diabetes (E10-E14) during at least two outpatient visits or one hospitalization. Direct costs included medical costs for the diagnosis and treatment of diabetes and transportation costs. Indirect costs included productivity loss costs due to morbidity and premature death and caregivers’ costs. Subgroup analyses were conducted according to the type of diabetes, age (< 65 vs. ≥65), diabetes medication, experience of hospitalization, and presence of diabetic complications or related comorbidities. Results A total of 4,472,133 patients were diagnosed with diabetes in Korea in 2017. The average annual prevalence of diabetes was estimated at 10.7%. The diabetes-related economic burden was USD 18,293 million, with an average per capita cost of USD 4090 in 2019. Medical costs accounted for the biggest portion of the total cost (69.5%), followed by productivity loss costs (17.9%), caregivers’ costs (10.2%), and transportation costs (2.4%). According to subgroup analyses, type 2 diabetes, presence of diabetic complications or related comorbidities, diabetes medication, and hospitalization represented the biggest portion of the economic burden for diabetes. As the number of complications increased from one to three or more, the per capita cost increased from USD 3991 to USD 11,965. In inpatient settings, the per capita cost was ~ 10.8 times higher than that of outpatient settings. Conclusions South Korea has a slightly high prevalence and economic burden of diabetes. These findings highlight the need for effective strategies to manage diabetic patients and suggest that policy makers allocate more health care resources to diabetes. This is the first study on this topic, conducted using a nationally representative claims database in South Korea.

scholarly journals Genetic and Pathogenic Characterization of QX(GI-19)-Recombinant Infectious Bronchitis Viruses in South Korea

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1163
Author(s):  
So-Youn Youn ◽  
Ji-Youn Lee ◽  
You-Chan Bae ◽  
Yong-Kuk Kwon ◽  
Hye-Ryoung Kim
Keyword(s):  
Phylogenetic Analysis ◽  
Disease Prevention ◽  
South Korea ◽  
Prevention And Control ◽  
Genetic Recombination ◽  
Detection Methods ◽  
Infectious Bronchitis ◽  
Reference Sequences ◽  
And Control

Infectious bronchitis viruses (IBVs) are evolving continuously via genetic drift and genetic recombination, making disease prevention and control difficult. In this study, we undertook genetic and pathogenic characterization of recombinant IBVs isolated from chickens in South Korea between 2003 and 2019. Phylogenetic analysis showed that 46 IBV isolates belonged to GI-19, which includes nephropathogenic IBVs. Ten isolates formed a new cluster, the genomic sequences of which were different from those of reference sequences. Recombination events in the S1 gene were identified, with putative parental strains identified as QX-like, KM91-like, and GI-15. Recombination detection methods identified three patterns (rGI-19-I, rGI-19-II, and rGI-19-III). To better understand the pathogenicity of recombinant IBVs, we compared the pathogenicity of GI-19 with that of the rGI-19s. The results suggest that rGI-19s may be more likely to cause trachea infections than GI-19, whereas rGI-19s were less pathogenic in the kidney. Additionally, the pathogenicity of rGI-19s varied according to the genotype of the major parent. These results indicate that genetic recombination between heterologous strains belonging to different genotypes has occurred, resulting in the emergence of new recombinant IBVs in South Korea.

Bitter Taste of Paradise: North Korean Refugees in South Korea

2006 ◽  
Vol 6 (1) ◽  
pp. 105-137 ◽  
Author(s):  
Andrei Lankov
Keyword(s):  
South Korea ◽  
Social Adjustment ◽  
Bitter Taste ◽  
Korean Society ◽  
South Korean ◽  
The Past ◽  
The North ◽  
North Korean Refugees ◽  
North Korean Defectors ◽  
To Come

This article deals with the problems of North Korean defectors currently living in South Korea. In the past, most such defectors came from privileged groups in the North Korean population, and their adjustment to the new environment did not pose a significant problem. However, from the mid-1990s, defectors began to come from the far less privileged groups. They experience serious problems related to jobs, education, crime, and social adjustment. Recent years have seen a dramatic but not always openly stated change in the official South Korean attitude toward defectors: from a policy explicitly aimed at encouraging defection, Seoul has moved to the policy of quietly discouraging it. There are fears that encouraging defection will undermine the policy of peaceful engagement with the North. There is also the perception that refugees are outsiders, not quite adjustable to the conditions of South Korean society and thus a social and budgetary burden.

The Origins of the Park Jung-hee Syndrome in South Korea

2019 ◽  
Vol 55 (01) ◽  
pp. 1950003
Author(s):  
EUNJUNG CHOI ◽  
JONGSEOK WOO
Keyword(s):  
National Identity ◽  
South Korea ◽  
Political Socialization ◽  
Empirical Test ◽  
Electoral Politics ◽  
The Political ◽  
South Korean ◽  
The Past ◽  
System Output ◽  
The Empirical Analysis

In the past few decades, post-democratization politics in South Korea have witnessed an upsurge in authoritarian nostalgia, called the “Park Jung-hee syndrome.” This paper examines the origins of public nostalgia for the authoritarian dictator by putting two theoretical arguments, i.e., the socialization thesis and the system output thesis, to an empirical test. This paper utilizes the 2010 Korea Democracy Barometer from the Korea Barometer and the 2010 and the 2015 Korean National Identity Survey from the East Asia Institute. The empirical analysis of the South Korean case strongly supports the political socialization argument, suggesting that citizens’ yearning for Park Jung-hee is not merely an outcome of the negative evaluations of the democratic governments’ performances. Rather, their authoritarian nostalgia is in large part an outcome of their political socialization during the Park dictatorship. The analysis implies that, although a resurgence of the Park Jung-hee syndrome in post-democratization South Korea is not expected to derail the country’s route to democratic deepening, it may continue to be a main source of political division in partisan and electoral politics in the future.

scholarly journals Koreańska fala, czyli wpływ i rozprzestrzenianie się kultury koreańskiej w krajach europejskich i amerykańskich

2021 ◽  
Vol 19 ◽  
pp. 209-218
Author(s):  
Marlena Oleksiuk
Keyword(s):  
South Korea ◽  
European Countries ◽  
Korean Culture ◽  
South Korean ◽  
The Past ◽  
Language History ◽  
Korean Wave ◽  
The World ◽  
Culture Start ◽  
Korean Food

The Korean wave, the influence and spread of Korean culture in European and American countries The Korean wave, especially over the past few years, has had a significant impact on the world. More and more people have begun to be interested in the culture of South Korea to a greater or lesser extent. Some people are interested only in K-pop or Korean series, but there are many people who expand their interest in Korean culture, start learning the language, history, and customs. Of all aspects of South Korean culture, K-pop is certainly the most popular. Much more artists organize concert tours for the benefit of European countries and America, in 2019, in Poland there were 15 such concerts. More and more often, Korean food festivals, stationary stores selling Korean cosmetics and food products are organized, in some countries, there even appear themed dance schools focusing on learning specific K-pop dance arrangements. The Korean wave also affects the perception of beauty by people – in 2018, on the annual list of the most handsome men, there appeared much more Koreans than in previous years, even members of the BTS group occupy the first places on the list.

scholarly journals Genetic Analysis of Avian Coronavirus Infectious Bronchitis Virus in Yellow Chickens in Southern China over the Past Decade: Revealing the Changes of Genetic Diversity, Dominant Genotypes, and Selection Pressure

Viruses ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 898 ◽  
Author(s):  
Wensheng Fan ◽  
Ning Tang ◽  
Zhihua Dong ◽  
Jiming Chen ◽  
Wen Zhang ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Infectious Bronchitis Virus ◽  
Selection Pressure ◽  
Southern China ◽  
Structural Genes ◽  
Infectious Bronchitis ◽  
The Past ◽  
New Type ◽  
Dominant Genotype

The high mutation rates of infectious bronchitis virus (IBV) pose economic threats to the poultry industry. In order to track the genetic evolutionary of IBV isolates circulating in yellow chickens, we continued to conduct the genetic analyses of the structural genes S1, E, M, and N from 64 IBV isolates in southern China during 2009–2017. The results showed that the dominant genotypes based on the four genes had changed when compared with those during 1985–2008. Based on the S1 gene phylogenetic tree, LX4-type (GI-19) was the most dominant genotype, which was different from that during 1985–2008. The second most dominant genotype was LDT3-A-type, but this genotype disappeared after 2012. New-type 1 (GVI-1) isolates showed increasing tendency and there were four aa (QKEP) located in the hypervariable region (HVR) III and one aa (S) insertion in all the New-type 1 isolates. Both the analyses of amino acid entropy and molecular evolutionary rate revealed that the variations from large to small were S1, E, M, and N. Purifying selection was detected in the S1, E, M, and N gene proteins, which was different from the positive selection during 1985–2008. Six isolates were confirmed to be recombinants, possibly generated from a vaccine virus of the 4/91-type or LDT3-A-type and a circulating virus. The estimated times for the most recent common ancestors based on the S1, E, M, and N genes were the years of 1744, 1893, 1940, and 1945, respectively. Bayesian skyline analysis revealed a sharp decrease in genetic diversity of all the four structural genes after 2010 and since late 2015, the viral population rapidly rose. In conclusion, the IBVs circulating in southern China over the past decade have experienced a remarkable change in genetic diversity, dominant genotypes, and selection pressure, indicating the importance of permanent monitoring of circulating strains and the urgency for developing new vaccines to counteract the emerging LX4-type and New-type IBVs.

Phylogenetic Analysis of S1 Gene of Infectious Bronchitis Virus Isolates from China

2011 ◽  
Vol 55 (3) ◽  
pp. 451-458 ◽  
Author(s):  
Fang Yan ◽  
Yujun Zhao ◽  
Wenbin Yue ◽  
Yao J ◽  
Lihua Lv ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Infectious Bronchitis Virus ◽  
S1 Gene ◽  
Infectious Bronchitis ◽  
Virus Isolates
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