scholarly journals Relics and Historical Uses of Human Zootherapeutic Products in Contemporary Spanish Ethnoveterinary Medicine

2021 ◽  
Vol 8 (12) ◽  
pp. 323
Author(s):  
José A. González ◽  
José Ramón Vallejo
Keyword(s):  
Teaching And Learning ◽  
Historical Data ◽  
New Drugs ◽  
Early 20Th Century ◽  
Traditional Practices ◽  
Ethnoveterinary Medicine ◽  
Documentary Sources ◽  
Progressive Loss ◽  
Therapeutic Tools ◽  
Menstrual Fluid

(1) Background: this review documents the wide repertoire of practices and remedies based on the use of human-derived products in Spanish ethnoveterinary medicine (EVM) from the early 20th century to the present. These practices are compared with historical data and those of other countries; (2) Methods: a search using advanced functions in the most important databases in the fields of ethnobiology, EVM, folklore, and ethnography was performed. Information was obtained from 29 documentary sources; (3) Results: from the search of the literature, 46 use-reports related to the veterinary use of human urine, menstrual fluid, saliva, breast milk, and faeces were recorded. These zootherapeutic resources are/were used to treat 20 animal diseases, in particular dermatological ailments. In addition, many practices of the magical–religious type are documented; (4) Conclusions: the veterinary uses described and analysed here are fundamental to the development of therapeutic tools and creating teaching and learning processes in new popular veterinary practices adapted to the users and those who demand them. The information collected could form a scientific foundation for future inventories of local veterinary knowledge (LVK) and research addressing the discovery of new drugs for livestock. This work contributes to the inventory of some uses, traditional practices, and rituals seriously threatened by the progressive loss of LVK in Europe.

scholarly journals The Birth and Death of the Russian House in the Priargun’ie Three Rivers Region, People’s Republic of China (1)

Folklorica ◽  
2015 ◽  
Vol 18 ◽  
Author(s):  
Vladimir Klyaus
Keyword(s):  
20Th Century ◽  
19Th Century ◽  
Early 20Th Century ◽  
Traditional Practices ◽  
Soviet Rule ◽  
Late 19Th Century ◽  
Republic Of China ◽  
Three Rivers Region ◽  
Three Rivers ◽  
Over Time

This article considers the remnants of Russian ritual practices surrounding houses in the Priangun’ie region of China. This region was populated by Russians from the late 19th century on. A large group of immigrants (Russian, Tungus and Buriat) immigrated there from the Transbaikal region of Russia after the establishment of Soviet rule in the early 20th century. The paper examines what remains of Russian traditional practices, how they have been blended with native Chinese traditions, and adapted over time to reflect intermarriage between people of Chinese or Tungus and Russian descent.

scholarly journals Molecular Modeling Studies of Piperidine Derivatives as New Acetylcholinesterase Inhibitors against Neurodegenerative Diseases

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Elaine F. F. da Cunha ◽  
José E. Resende ◽  
Tanos C. C. Franca ◽  
Mateus Aquino Gonçalves ◽  
Felipe R. de Souza ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Molecular Modeling ◽  
Neurodegenerative Disorders ◽  
Acetylcholinesterase Inhibitors ◽  
Molecular Target ◽  
New Drugs ◽  
Ache Inhibitors ◽  
Progressive Loss ◽  
Molecular Modeling Studies ◽  
Dynamics Simulations

Neurodegenerative disorders are related to the progressive loss of structure or function and, eventually, death of neurons. These processes are responsible for diseases like Parkinson’s, Alzheimer’s, and Huntington’s, and the main molecular target for the drug design against these illnesses today is the enzyme acetylcholinesterase (AChE). Following this line, in the present work, we applied docking techniques to study some piperidine derivative inhibitors of AChE and further propose structures of six new AChE inhibitors as potential new drugs against neurodegenerative disorders. The best inhibitor proposed was submitted to additional molecular dynamics simulations steps.

Signaling the end of chronic lymphocytic leukemia: new frontline treatment strategies

Blood ◽  
2013 ◽  
Vol 122 (23) ◽  
pp. 3723-3734 ◽  
Author(s):  
Michael Hallek
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Genetic Parameters ◽  
Treatment Strategies ◽  
Lymphocytic Leukemia ◽  
New Drugs ◽  
The Novel ◽  
Frontline Treatment ◽  
Therapeutic Tools ◽  
The Right ◽  
Near Future

AbstractThe management of chronic lymphocytic leukemia (CLL) is undergoing profound changes. Several new drugs have been approved for CLL treatment (fludarabine, bendamustine, and the monoclonal antibodies alemtuzumab, rituximab, and ofatumumab) and many more drugs are in advanced clinical development to be approved for this disease. In addition, the extreme heterogeneity of the clinical course and our improved ability to foresee the prognosis of this leukemia by the use of clinical, biological, and genetic parameters now allow us to characterize patients with a very mild onset and course, an intermediate prognosis, or a very aggressive course with high-risk leukemia. Therefore, it becomes increasingly challenging to select the right treatment strategy for each condition. This article summarizes the currently available diagnostic and therapeutic tools and gives an integrated recommendation of how to manage CLL in 2013. Moreover, I propose a strategy how we might integrate the novel agents for CLL therapy into sequential treatment approaches in the near future.

scholarly journals Importancia del uso de recursos didácticos en el proceso de enseñanza y aprendizaje de las ciencias biológicas para la estimulación visual del estudiantado

2017 ◽  
Vol 21 (2) ◽  
pp. 1 ◽  
Author(s):  
Josmary Celinda Suárez-Ramos
Keyword(s):  
Biological Sciences ◽  
Systematic Review ◽  
Teaching And Learning ◽  
Visual Stimulation ◽  
Human Beings ◽  
Documentary Sources ◽  
Primary Representation ◽  
Planning Strategies ◽  
Visual Impact ◽  
Stimulation Of

 This article aims to conduct a literature review on documentary sources approaching aspects related to the importance of the use of didactic resources in the teaching and learning process of biological sciences. The paper focuses on the visual stimulation of students, and considers important information in the field of biological sciences, pedagogy and didactics. Through a systematic review, bibliographical and electronic sources were selected; they were published in a period from 1983 to 2013. The article describes some of the main didactic resources producing greater visual impact in the students and turning into meaningful learning through their incorporation into the cerebral cortex. Findings suggest that the individuals’ learning is mediated by the nervous system and the sensory organs. Likewise, studies have verified that the sense of sight is the system of primary representation for most human beings, and the teaching strategies combining vision with hearing have considerable possibilities of being more effective. It is concluded that the use of adequate didactic resources is indispensable to optimize students’ learning in terms of content in the area of biological sciences. So it is recommended that teachers consider these realities when planning strategies to teach their classes.

Structural and Biological Overview of Boron-containing Amino Acids in the Medicinal Chemistry Field

2019 ◽  
Vol 26 (26) ◽  
pp. 5077-5089 ◽  
Author(s):  
Antonio Abad García ◽  
Alexey Rayevsky ◽  
E. Andrade-Jorge ◽  
José G. Trujillo-Ferrara
Keyword(s):  
Amino Acids ◽  
Biological Activity ◽  
Biological Effect ◽  
Drug Targets ◽  
New Drugs ◽  
Toxicological Profile ◽  
Therapeutic Tools ◽  
The Stability ◽  
Relationship Of ◽  
Derivatives Of

Background: Amino acids are the basic structural units of proteins as well as the precursors of many compounds with biological activity. The addition of boron reportedly induces changes in the chemical-biological profile of amino acids. Methods: We compiled information on the biological effect of some compounds and discussed the structure-activity relationship of the addition of boron. The specific focus presently is on borinic derivatives of α-amino acids, the specific changes in biological activity caused by the addition of a boron-containing moiety, and the identification of some attractive compounds for testing as potential new drugs. Results: Borinic derivatives of α-amino acids have been widely synthesized and tested as potential new therapeutic tools. The B-N (1.65 A°) or B-C (1.61 A°) or B-O (1.50 A°) bond is often key for the stability at different pHs and temperatures and activity of these compounds. The chemical features of synthesized derivatives, such as the specific moieties and the logP, polarizability and position of the boron atom are clearly linked to their pharmacodynamic and pharmacokinetic profiles. Some mechanisms of action have been suggested or demonstrated, while those responsible for other effects remain unknown. Conclusion: The increasing number of synthetic borinic derivatives of α-amino acids as well as the recently reported crystal structures are providing new insights into the stability of these compounds at different pHs and temperatures, their interactions on drug targets, and the ring formation of five-membered heterocycles. Further research is required to clarify the ways to achieve specific synthesis, the mechanisms involved in the observed biological effect, and the toxicological profile of this type of boron-containing compounds (BCCs).

scholarly journals Modern Hindu Intellectuals and Ancient Texts: Reforming Śaiva Yoga in Bali

2013 ◽  
Vol 169 (1) ◽  
pp. 68-103 ◽  
Author(s):  
Andrea Acri
Keyword(s):  
20Th Century ◽  
Historical Data ◽  
Religious Discourse ◽  
Early 20Th Century ◽  
Main Concern ◽  
Cultural Dynamics ◽  
Continuity And Change ◽  
Fresh Perspective ◽  
Ancient Texts

Abstract This article aims at providing a fresh perspective on the modern, reformed version of ‘Balinese Hinduism’ that came to the fore on the island since the early 20th century. It describes certain important elements of doctrinal continuity and change in the light of the pre-colonial Śaiva religious discourse, on the basis of textual and historical data that have so far been neglected. It attempts to show that the Javano-Balinese theological tradition is characterized by a remarkable continuity, especially when it comes to its exegetical and text-building practices, but also by important elements of changes. To investigate the nature of such changes—in particular the treatment of Yoga in selected textual sources—and the historical and cultural dynamics behind them is the main concern of this article.

scholarly journals Indian Traditional Ayurvedic System of Medicine and Nutritional Supplementation

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
M. M. Pandey ◽  
Subha Rastogi ◽  
A. K. S. Rawat
Keyword(s):  
Evidence Base ◽  
Emerging Diseases ◽  
New Drugs ◽  
Traditional Practices ◽  
Working Population ◽  
Traditional Herbal Medicine ◽  
Alternative Medicines ◽  
Nutritional Needs ◽  
Traditional Indian Medicine ◽  
Indian Medicine

Food is the major source for serving the nutritional needs, but with growing modernization some traditional ways are being given up. Affluence of working population with changing lifestyles and reducing affordability of sick care, in terms of time and money involved, are some of the forces that are presently driving people towards thinking about their wellness. There has been increased global interest in traditional medicine. Efforts to monitor and regulate traditional herbal medicine are underway. Ayurveda, the traditional Indian medicine, remains the most ancient yet living traditions. Although India has been successful in promoting its therapies with more research and science-based approach, it still needs more extensive research and evidence base. Increased side effects, lack of curative treatment for several chronic diseases, high cost of new drugs, microbial resistance and emerging, diseases are some reasons for renewed public interest in complementary and alternative medicines. Numerous nutraceutical combinations have entered the international market through exploration of ethnopharmacological claims made by different traditional practices. This review gives an overview of the Ayurvedic system of medicine and its role in translational medicine in order to overcome malnutrition and related disorders.

scholarly journals The use of gamification to teach in the nursing field

2018 ◽  
Vol 71 (3) ◽  
pp. 1038-1045 ◽  
Author(s):  
Talita Candida Castro ◽  
Luciana Schleder Gonçalves
Keyword(s):  
Quantitative Analysis ◽  
Nursing Students ◽  
Technological Innovation ◽  
Student Motivation ◽  
Teaching And Learning ◽  
Traditional Practices ◽  
Content Structure ◽  
Qualitative And Quantitative ◽  
Innovation Research ◽  
Teaching Learning

ABSTRACT Objectives: To investigate whether the course offer with elements of gamification contributes to the formation of competences in Informatics in Nursing; and evaluate it based on teaching and learning criteria and content structure. Method: Exploratory, applied and technological innovation research, with a qualitative and quantitative approach, developed at a university in the southern region of the country between February and November 2016. Participants were professors (5) and nursing students (10). Results: The adoption of gamification was considered an interesting and innovative approach, as an alternative to traditional practices and applicable to Nursing teaching. In the quantitative analysis, it was observed that the course contemplates the set of evaluated criteria. Final considerations: Gamification contributes to the formation of competences among Nursing students for positively influencing the teaching-learning process. It can be understood as one more resource in the teaching work with a view to student motivation and meaningful learning.

scholarly journals PERANCANGAN SISTEM DATA WAREHOUSE PEMBELAJARAN PADA PONDOK PESANTREN AL-FURQON

2017 ◽  
Vol 3 (1) ◽  
pp. 110-122
Author(s):  
Padeli Padeli ◽  
Muhammad Dzulfikar Allam ◽  
Nurviani Riska Suharto
Keyword(s):  
Data Analysis ◽  
Literature Review ◽  
Data Warehouse ◽  
Teaching And Learning ◽  
Storage Capacity ◽  
Historical Data ◽  
Boarding School ◽  
Process Data ◽  
Faith Based ◽  
Collection Methods

Al-furqon is foundation of faith-based education that is commonly called the boarding school. Along with the increasing number of students each year the more the teacher or teachers who will take part in the activities of teaching and learning. Thus the more the data that goes into the institution or Pondok Pesantren Al-furqon, these data would need to be stored, processed, and analyzed to produce a useful information for the institution, and reported to the Ministry of Religious Affairs in charge of boarding school. Meanwhile, to make the report, it takes more time to collect information and process data stored in operational databases in the institution. Since it is considered necessary to manage large amounts of data in order to produce an information quickly, then made a design of the data warehouse to facilitate the conduct of data processing, analyzing and reporting the data analysis. The method used the data collection methods, such as observation, interviews, and literature review. After getting the data and then analyzed with the SWOT method, this method describes the shortcomings, strengths and opportunities for improvement in the system. This research resulted in a data warehouse for Al-furqon institution, as well as the amount of storage capacity needed for historical data.

scholarly journals Earthquakes and tsunami in November 1755 in Morocco: a different reading of contemporaneous documentary sources

2009 ◽  
Vol 9 (3) ◽  
pp. 725-738 ◽  
Author(s):  
P.-L. Blanc
Keyword(s):  
Critical Analysis ◽  
Historical Data ◽  
Seismic Source ◽  
Not Given ◽  
Tsunami Waves ◽  
Documentary Sources ◽  
Astronomical Tide ◽  
Lisbon Earthquake ◽  
Tide Level ◽  
Run Up

Abstract. Tsunami seldom strike the European Atlantic shores. The great Lisbon Earthquake of 1 November 1755 is the main destructive tsunamigenic event recorded. Since the mid-1990's, many simulations of propagation of tsunami waves from variants of the possible seismic source have been conducted. Estimates of run-up in Morocco are seldom included in publications, maybe for want of reliable historical data to control the simulations. This paper revisits some early accounts, transmitted as translations to European Chanceries, Scientific Societies and Newspapers. A critical analysis of the documents leads us to conclude that the Lisbon earthquake was overestimated because of amalgamation with a later Rifian earthquake. Then, the overestimation of the tsunami through worst interpretation of the scant data available appeared only reasonable, while the moderate measurements or interpretations were not given their due attention. In Morocco the amplitude of the tsunami (i.e. height at shoreline minus expected tide level) may not have exceed the measurement given by Godin (1755) for Cadiz, 2.5 m above the calculated astronomical tide, a crest-to-trough amplitude of 5 m at most. This age-old overestimation of both the earthquake and tsunami is detrimental to the evaluation of the risk for coastal people and activities.

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