Indications and Contraindications for Cystography, Diagnostic Value of the Method

2020 ◽  
pp. 54-59
Author(s):  
Roman Petrovich Stepchenkov
Keyword(s):  
Clinical Picture ◽  
Inflammatory Diseases ◽  
Diagnostic Value ◽  
Diagnostic Methods ◽  
General Analysis ◽  
Malignant Neoplasms ◽  
Urinary System ◽  
Bladder Abnormalities ◽  
Rupture Of The Bladder

Diseases of the urinary system are quite common, both among adults and among children. If, in case of infectious and inflammatory diseases of the urinary organs, an assessment of the clinical picture and general analysis of the urine is sufficient to make a diagnosis, in a number of other situations — trauma and rupture of the bladder, abnormalities of its development, malignant neoplasms — visualization of the organ is needed. One of these diagnostic methods is cystography.

scholarly journals Cooper’s syringocele (bulbourethral cyst)

2021 ◽  
Vol 11 (2) ◽  
pp. 175-182
Author(s):  
Vladimir V. Protoshchak ◽  
Аlexey A. Sivakov ◽  
Sergei M. Gozalishvili ◽  
Vasiliy K. Karandashov ◽  
Alexandr E. Gorbunov
Keyword(s):  
Inflammatory Diseases ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
General Analysis ◽  
Foreign Literature ◽  
External Opening ◽  
Child Population ◽  
Analysis Of Urine

Bulbourethral cyst or Cowpers syringocele (from the Greek syringe tube, cele expansion) is a cystic expansion of the excretory ducts of the bulbourethral glands (Cowpers glands). This disease is extremely rare and is more often diagnosed in the child population. The clinical manifestations of syringocele are non-specific and depend on many factors: size, localization, communication with the urethra, and the presence of an infectious component. Detection of syringocele is impossible without the use of special radiation and endoscopic diagnostic methods. Most often, this pathology is masked under inflammatory diseases of the genitals due to the fact that the symptoms are limited to secretions from the external opening of the urethra, changes in the general analysis of urine and dysuric manifestations. Currently in the domestic and foreign literature there are not even 20 publications devoted to this pathology.

scholarly journals Possibilities of topical treatment of inflammatory diseases of vulva and vagina in girls

2017 ◽  
Vol 8 (3) ◽  
pp. 88-93 ◽  
Author(s):  
Anna V Mironova ◽  
Ivan I Chernichenko
Keyword(s):  
Clinical Picture ◽  
Inflammatory Process ◽  
Inflammatory Diseases ◽  
Local Treatment ◽  
Clinical Manifestations ◽  
Ease Of Use ◽  
Diagnostic Methods ◽  
Minimal Risk ◽  
Childhood Infections ◽  
Frequent Reason

Vulvitis and vaginitis in girls are the most frequent reason for contacting a pediatric gynecologist. The article considers options for local treatment with various forms of inflammation of the vulva and vagina. In recent years, there has been an increase in this pathology. The maximum number of appeals is observed at 1 year of age and at the age of 3-7 years. The formation of the inflammatory process in the vagina is caused by the state of the endocrine and immune systems, as well as a number of anatomical and physiological features of the structure of the external sexual organs. An important role in the development of vulvovaginitis and vulvitis is played by extragenital pathology. The development of the secondary inflammatory process in the vagina provokes such diseases as urinary tract infection, dysbacteriosis, atopic dermatitis, noopharyngeal diseases, frequent colds, transient immunodeficiency states, childhood infections. The clinical manifestations of vulva-guinitis and vulvitis are similar and depend on the severity of the process, the type of exciter. In acute nonspecific vulvovaginitis, a vivid clinical picture is typical. This discharge from the genital tract, hyperemia and swelling of the vulva, discomfort, burning with urination. The diagnosis of the disease is based on the details of complaints, clinical picture, laboratory and instrumental diagnostic methods. In the treatment of non-specific vulvovaginitis, girls rarely resort to the use of systemic antibacterial drugs. Preference is given to topical preparations. The advantage of local treatment is a minimal risk of adverse reactions, simplicity and ease of use, in the absence of contraindications (except for individual intolerance of the drug), as well as in the possibility of use in extragenital pathology.

Diagnostic value of fatty acid-binding protein determination in urologists and nephrologists clinical practice

2020 ◽  
pp. 92-99
Author(s):  
Konstantin R. Galkovich
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Physiological Role ◽  
Diagnostic Value ◽  
Obstructive Nephropathy ◽  
Malignant Neoplasms ◽  
Early Screening ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

This review summarizes the data on the diagnostic value of determining the fatty acid-binding protein (FABP) in urological and nephrological diseases. A physiological role of this protein in the pathogenesis of malignant neoplasms of the kidney, bladder, and prostate was analyzed. The dynamics of FABP in serum and urine with decreased renal function was studied: this protein is considered as a diagnostic and prognostic marker for chronic kidney disease and acute renal injury. The value of FABP for early screening of patients with obstructive nephropathy was revealed, and its role in predicting the restoration of kidney function was studied: the dynamics of FABP content can characterize the process of graft recovery, determine the need for hemodialysis. In patients with oligozooastenospermia, a reduced content of FABP in the ejaculate was registered, which was probably an adverse sign indicating a violation of male fertility.

Diagnostic Value of Non-Invasive Prenatal Screening of β-thalassemia by Cell Free Fetal DNA and Fetal NRBC

2019 ◽  
Vol 19 (2) ◽  
pp. 105-111
Author(s):  
Nadia Shafei ◽  
Mohammad Saeed Hakhamaneshi ◽  
Massoud Houshmand ◽  
Siavash Gerayeshnejad ◽  
Fardin Fathi ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Multiple Displacement Amplification ◽  
Diagnostic Value ◽  
Diagnostic Methods ◽  
Beta Thalassemia ◽  
Non Invasive ◽  
Fetal Dna ◽  
Prenatal Diagnostic ◽  
Cell Free Fetal Dna ◽  
Invasive Techniques

Background: Beta thalassemia is a common disorder with autosomal recessive inheritance. The most prenatal diagnostic methods are the invasive techniques that have the risk of miscarriage. Now the non-invasive methods will be gradually alternative for these invasive techniques. Objective: The aim of this study is to evaluate and compare the diagnostic value of two non-invasive diagnostic methods for fetal thalassemia using cell free fetal DNA (cff-DNA) and nucleated RBC (NRBC) in one sampling community. Methods: 10 ml of blood was taken in two k3EDTA tube from 32 pregnant women (mean of gestational age = 11 weeks), who themselves and their husbands had minor thalassemia. One tube was used to enrich NRBC and other was used for cff-DNA extraction. NRBCs were isolated by MACS method and immunohistochemistry; the genome of stained cells was amplified by multiple displacement amplification (MDA) procedure. These products were used as template in b-globin segments PCR. cff-DNA was extracted by THP method and 300 bp areas were recovered from the agarose gel as fetus DNA. These DNA were used as template in touch down PCR to amplify b-globin gen. The amplified b-globin segments were sequenced and the results compared with CVS resul. Results: The data showed that sensitivity and specificity of thalassemia diagnosis by NRBC were 100% and 92% respectively and sensitivity and specificity of thalassemia diagnosis by cff-DNA were 100% and 84% respectively. Conclusion: These methods with high sensitivity can be used as screening test but due to their lower specificity than CVS, they cannot be used as diagnostic test.

Endobronchial Ultrasound Multimodal Imaging for the Diagnosis of Intrathoracic Lymph Nodes

Respiration ◽  
2021 ◽  
pp. 1-11
Author(s):  
Xinxin Zhi ◽  
Junxiang Chen ◽  
Lei Wang ◽  
Fangfang Xie ◽  
Xiaoxuan Zheng ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Multimodal Imaging ◽  
Single Mode ◽  
Diagnostic Value ◽  
Diagnostic Methods ◽  
Endobronchial Ultrasound ◽  
Diagnostic Efficiency ◽  
Validation Group ◽  
Model Group ◽  
Structure Heterogeneity

<b><i>Background:</i></b> Endobronchial ultrasound (EBUS) imaging is valuable in diagnosing intrathoracic lymph nodes (LNs), but there has been little analysis of multimodal imaging. This study aimed to comprehensively compare the diagnostic performance of single and multimodal combinations of EBUS imaging in differentiating benign and malignant intrathoracic LNs. <b><i>Methods:</i></b> Subjects from July 2018 to June 2019 were consecutively enrolled in the model group and July 2019 to August 2019 in the validation group. Sonographic features of three EBUS modes were analysed in the model group for the identification of malignant LNs from benign LNs. The validation group was used to verify the diagnostic efficiency of single and multimodal diagnostic methods built in the model group. <b><i>Results:</i></b> 373 LNs (215 malignant and 158 benign) from 335 subjects and 138 LNs (79 malignant and 59 benign) from 116 subjects were analysed in the model and validation groups, respectively. For single mode, elastography had the best diagnostic value, followed by grayscale and Doppler. The corresponding accuracies in the validation group were 83.3%, 76.8%, and 71.0%, respectively. Grayscale with elastography had the best diagnostic efficiency of multimodal methods. When at least two of the three features (absence of central hilar structure, heterogeneity, and qualitative elastography score 4–5) were positive, the sensitivity, specificity, and accuracy in the validation group were 88.6%, 78.0%, and 84.1%, respectively. <b><i>Conclusions:</i></b> In both model and validation groups, elastography performed the best in single EBUS modes, as well as grayscale combined with elastography in multimodal imaging. Elastography alone or combined with grayscale are feasible to help predict intrathoracic benign and malignant LNs.

Congenital optic disc coloboma

2021 ◽  
pp. 33-39
Author(s):  
A.O. Nazarenko ◽  
◽  
E.E. Sidorenko ◽  
D.V. Miguel ◽  
A.S. Smartsev ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Optic Nerve ◽  
Clinical Picture ◽  
Clinical Case ◽  
Charge Syndrome ◽  
Diagnostic Methods ◽  
Newly Diagnosed ◽  
Optic Nerve Atrophy ◽  
Optic Disc Coloboma ◽  
Optic Nerve Coloboma

A clinical case of observation of a 3-year-old child with a newly diagnosed optic nerve coloboma and multiple malformations is considered. The clinical picture and diagnostic methods necessary for the diagnosis are reflected. On the example of this child, the differential diagnosis with Charge syndrome is considered. Key words: coloboma, optic nerve coloboma, partial optic nerve atrophy, astigmatism, Charge syndrome.

scholarly journals Spontaneous Bladder Rupture after Normal Vaginal Delivery: Description of a Rare Complication and Systematic Review of the Literature

Diagnostics ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1885
Author(s):  
Guglielmo Stabile ◽  
Francesco Cracco ◽  
Davide De Santo ◽  
Giulia Zinicola ◽  
Federico Romano ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Vaginal Delivery ◽  
Rare Complication ◽  
Diagnostic Methods ◽  
Pelvic Surgery ◽  
Bladder Rupture ◽  
Normal Vaginal Delivery ◽  
X Rays ◽  
Spontaneous Bladder Rupture ◽  
Rupture Of The Bladder

Objective: To identify the possible causes of spontaneous bladder rupture after normal vaginal delivery and to propose a diagnostic and therapeutic algorithm. Material and Methods: MEDLINE (PubMed), Web of Science and Scopus databases were searched up to August 2020. Manuscripts considered were published from 1990 and only English articles were included. The research strategy adopted included the following terms: (bladder rupture) AND (spontaneous) AND (delivery). 103 studies were identified. Duplicates were found through an independent manual screening. Subsequently, two authors independently screened the full text of articles and excluded those not pertinent to the topic. Discrepancies were resolved by consensus. Finally, thirteen studies were included. Results: PRISMA guidelines were followed. For each study, fetal weight, catheterization during labor, parity, maternal age, occurrence time, previous abdominal or pelvic surgery, symptoms complained of, diagnostic methods, and treatment were considered. Median age was 26.0 (range 20–34 years); median presentation time was 3.0 days after delivery (range 1–20 days); and median newborn weight was 3227.0 g (range 2685–3600 g). Catheterization during labor was reported only in four of the thirteen cases (30.8%) identified. The symptoms most frequently complained of were abdominal pain and distension, fever, oliguria, haematuria and vomiting. Instrumental diagnosis was performed using X-rays in five cases and computerized tomography in six cases. Ultrasound was chosen in five cases as a first diagnostic tool. In two cases, cystography was performed. Treatment was always laparotomic repair of the visceral defect. Conclusion: Abdominal pain, increased creatinine and other signs of kidney failure on blood tests should lead to suspicion of this complication. Cystourethrography is regarded as a procedure of choice, but a first ultrasound approach is recommended. The main factor for the therapeutic choice is the intraperitoneal or extraperitoneal rupture of the bladder. Classical management for intraperitoneal rupture of the bladder is surgical repair and urinary rest.

scholarly journals PATHOGENETIC JUSTIFICATION OF NEW APPROACHES TO THE ASSESSMENT OF THE STATE OF ORAL CAVITY IN CHRONIC GENERALIZED PARODONTITIS

2018 ◽  
Vol 14 (4) ◽  
pp. 14-18 ◽  
Author(s):  
Владимир Базарный ◽  
Vladimir Bazarnyy ◽  
Лариса Полушина ◽  
Larisa Polushina ◽  
Арина Максимова ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Clinical Manifestations ◽  
Diagnostic Value ◽  
Diagnostic Methods ◽  
Cochrane Library ◽  
Russian State ◽  
State Library ◽  
The Cochrane Library ◽  
Diagnostic Capabilities ◽  
Diagnostic Technologies

Introduction. A variety of concepts and approaches to the analysis of the etiology and pathogenesis of temporomandibular joint dysfunctions, results in increased interest in the search for highly informative diagnostic methods, especially at the stage of pre-clinical manifestations. Objectives. The aim of the study was to analyze the possibilities of modern technologies in diagnostics of temporomandibular joint dysfunctions. Materials and methods. We studied original papers on the diagnostics of temporomandibular joint dysfunctions from several databases: Russian State Library, eLibrary, PubMed, The Cochrane Library, Google Scholar. Results. The review presents both generally accepted and alternative approaches to the diagnostics of different clinical manifestations in temporomandibular joint dysfunctions. We described the diagnostic value of occlusal disorders analysis in universal articulators, virtual articulators, T-scan system. Capabilities of teleroentgenography, axiography, electromyography, computed and magnetic resonance imaging were estimated as well. Conclusions. The literature review on the problem of diagnosing the temporomandibular joint dysfunctions showed a scientifically based spectrum of diagnostic capabilities of modern dentistry, a trend in the development of highly informative digital diagnostic technologies. Due to the diversity of the etiology and pathogenesis of the temporomandibular joint dysfunctions further in-depth studies of this issue are required.

scholarly journals Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer

2021 ◽  
Vol 8 ◽  
Author(s):  
Su-Ju Wei ◽  
Li-Ping Wang ◽  
Jun-Yan Wang ◽  
Jing-Xu Ma ◽  
Feng-Bin Chuan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Tumor Markers ◽  
Cancer Diagnosis ◽  
Diagnostic Value ◽  
Diagnostic Methods ◽  
Lung Cancer Diagnosis ◽  
Early Lung Cancer ◽  
Group A ◽  
Group B

Objective: The objective of this research is to explore the diagnostic value of imaging plus tumor markers in the early detection of lung cancer.Methods: Sixty patients with lung cancer treated in our hospital from January 2018 to January 2019 were selected as group A. They were matched with 60 patients with benign lung disease as group B and 60 healthy subjects examined in our hospital as group C. The carcino-embryonic antigen (CEA), CYFRA21-1, and neuron-specific enolase (NSE) were assessed, and the diagnostic value of tumor markers plus imaging in lung cancer diagnosis was explored.Results: The CEA, CYFRA21-1, and NSE in group A were evidently superior to those in groups B and C, and those in group B were superior to those in group C (all P &lt; 0.001). CEA had the highest sensitivity (56.7%), and NSE had the highest specificity (93.3%). The tumor markers plus imaging had the highest sensitivity for different types of lung cancer, and the sensitivity to early lung cancer (90%) was superior to other diagnostic methods (P &lt; 0.05).Conclusion: The tumor markers plus imaging is of great significance in early lung cancer diagnosis and provides a reference for judging the pathological classification.

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