Analysis of follow-up changes in incidence of oral diseases in Novosibirsk schoolchildren during the preventive treatment program

2021 ◽  
Vol 21 (2) ◽  
pp. 103-109
Author(s):  
T. I. Chebakova ◽  
N. A. Zagetova ◽  
E. H. Volkova ◽  
O. E. Ledovskikh
Keyword(s):  
Russian Federation ◽  
Treatment Program ◽  
Preventive Treatment ◽  
Dental Status ◽  
Oral Disease ◽  
Fluoride Varnish ◽  
Dental Hygienist ◽  
Oral Diseases ◽  
The Russian Federation

Relevance. The Russian Federation state program „Healthcare system development”, approved on April 15, 2014, relies on the introduction of the specialist „Dental Hygienist” in the system of school dentistry service as the main executor of the preventive treatment program. Government resolution #1640 as of 26.12.2017, which is to be realized during 2018-2025, included the agency project „“Primary prevention of oral diseases among the population of the Russian Federation”. The realization of the oral disease prevention project (professional cleaning, fluoride  local application, permanent molar fissure sealing) is a basic program that includes necessary steps to reduce oral disease incidence rate and caries increase in schoolchildren. Administration of oral care products (fluoride varnish, sealants) immediately after tooth eruption, i.e., during formation and mineralization of the hard dental tissues, is more relevant, than the use of these products after the mineralization is complete. Aim – to assess the effectiveness of oral disease preventive measures by the analysis of the follow-up changes in the dental status of schoolchildren.Materials and methods. 115 first-grade schoolchildren of two Novosibirsk general schools participated in the study. The schoolchildren were evenly divided into 2 groups: prevention and comparison. The parents and children of both groups were trained how to take care of the oral cavity at home. The children in both groups were examined, oral hygiene indices were determined and the teeth were treated. The preventive treatment in the first groups was administered with the following materials: fluoride varnish with innovative ingredient, tricalcium phosphate, and low fill fluoride-releasing light-cured sealant. The materials are certified and approved for use in children in the Russian Federation. The individual preventive treatment was not performed in the second group. The effectiveness of the preventive treatment was assessed by the analysis of follow-up changes in the dental status of the schoolchildren.Results. The school preventive treatment program demonstrated a significant reduction of caries increase rate – up to 31.79% in the prevention group, which forms the basis for performance optimization of the school dental office where the priority belongs to a dental hygienist.Conclusions. The results of the preventive treatment program with the participation of a pediatric dentist and a dental hygienist held in three Novosibirsk schools confirmed its high medical effectiveness.

scholarly journals UNESCO-Russia Mendeleev International Prize in the Basic Sciences

2021 ◽  
Vol 43 (1) ◽  
pp. 28-29
Keyword(s):  
Russian Federation ◽  
Periodic Table ◽  
Chemical Elements ◽  
Basic Sciences ◽  
The Russian Federation ◽  
The Government

Abstract As a follow-up to the 2019 International Year of the Periodic Table of Chemical Elements (IYPT2019), the Government of the Russian Federation proposed to establish and fund the joint UNESCO/Russian Federation International Prize for the Basic Sciences in the name of the Russian chemist Dmitry Mendeleev. The initiative is to provide further support to the UNESCO’s International Basic Sciences Programme (IBSP).

scholarly journals Peptides in COVID-19 Clinical Trials—A Snapshot

Biologics ◽  
2021 ◽  
Vol 1 (3) ◽  
pp. 300-311
Author(s):  
Kai Hilpert
Keyword(s):  
Clinical Trials ◽  
Antiviral Activity ◽  
Russian Federation ◽  
Current Situation ◽  
Routine Diagnostics ◽  
Current Review ◽  
The Usa ◽  
The Russian Federation ◽  
The Uk

Since the beginning of the COVID-19 pandemic, there has been a strong drive and desire to find effective treatments for and protection against the disease. On the webpage ClinicalTrials.gov, a total of 6505 clinical trials currently (September 2021) investigating various aspects of COVID-19 are registered. Of these, 124 studies involving peptides were identified. These 124 were further evaluated, and 88 trials that used peptides only for routine diagnostics were excluded. The remaining 36 trials were classified into 5 different classes according to their function: immunomodulatory (5 trials), regain homeostasis (10 trials), diagnostics/biomarkers (8 trials), vaccination (9 trials), and antiviral activity (4 trials, all overlap with immunomodulatory activities). In the current review, these 36 trials are briefly described and tabularly summarised. According to the estimated finish date, 14 trials have not yet finished. All of the finished trials are yet to report their results. Seven trials were based in the USA, and Egypt, France, the UK, Turkey, and the Russian Federation conducted three trials each. This review aims to present a snapshot of the current situation of peptides in COVID-19 clinical trials and provides a template to follow up on trials of interest; it does not claim to be a complete overview.

scholarly journals Administrative oversight: improving compliance practices

2021 ◽  
Vol 118 ◽  
pp. 03001
Author(s):  
Aleksander Nikolaevich Varygin ◽  
Irina Alekseevna Efremova ◽  
Vladimir Gennadievich Gromov ◽  
Pavel Anatolievich Matushkin ◽  
Anastasia Mikhailovna Shuvalova
Keyword(s):  
Russian Federation ◽  
Preventive Treatment ◽  
Integrated Approach ◽  
Federal Law ◽  
Scientific Methods ◽  
Administrative Supervision ◽  
Analysis And Synthesis ◽  
General Scientific ◽  
The Russian Federation ◽  
Administrative Oversight

The main purpose of the research is to determine the goals, objectives and functions of administrative supervision and develop proposals for improving the legislation of the Russian Federation regulating issues related to the implementation of administrative supervision. Research methods: general scientific methods (analysis and synthesis, logical methods) and private scientific methods of cognition (formally-legally, specifically-sociological etc.). Outcome: the author’s version of the administrative supervision goals and objectives set out in the regulatory documents of the Russian Federation is proposed: 1. Administrative supervision is established to prevent the commission of crimes and other offences by persons. 2. The administrative supervision focuses on implementation by the internal affairs bodies of supervision over the observance by supervised persons of temporary restrictions on their rights and freedoms, as well as over the fulfillment of their duties stipulated by the related federal law; identification of violations by those under the supervision and taking measures in accordance with the law; individual preventive treatment of such persons. The novelty of the study is due to an integrated approach to the research into the goals, objectives and functions of administrative supervision and the developed proposals for improving the Russian legislation regulating issues in that area.

Geriatric Health Experts Validate Oral Neglect Timelines for the Institutionalized Elderly

2019 ◽  
Vol 39 (11) ◽  
pp. 1250-1257
Author(s):  
Sharon M. Casey ◽  
Ralph V. Katz ◽  
Shulamite Huang ◽  
Barbara J. Smith
Keyword(s):  
Nursing Home ◽  
Nursing Homes ◽  
Nursing Home Residents ◽  
Standard Of Care ◽  
Delphi Survey ◽  
Oral Disease ◽  
Oral Diseases ◽  
Term Care ◽  
Institutionalized Elderly

The purpose of this follow-up Delphi survey was to have an expert panel of 31 academic geriatric physicians, geriatric nurses, and medical directors of nursing homes evaluate the original timeline set to avoid oral neglect of nursing home residents. The Oral Neglect in Institutionalized Elderly (ONiIE) timelines defined oral neglect as having occurred when >7 days for acute oral diseases/conditions or >34 days for chronic oral disease/conditions had passed between initial diagnosis and offering access to dental care to the long-term care (LTC) nursing home resident. The results of this follow-up Delphi survey validated those originally defined ONiIE timelines as 90% of this panel agreed with the original timelines. This ONiIE definition adds a broad-based validation for the ONiIE timelines for setting an oral health standard of care for institutionalized elderly residents of nursing homes and should now be used to protect the vulnerable elderly residing in LTC nursing homes.

scholarly journals Clinical performance of the atrial fibrillation in the Russian population depending on the antithrombotic therapy: findings from the GLORIA-AF registry phase 2

2020 ◽  
Vol 25 (11) ◽  
pp. 4179
Author(s):  
E. V. Shlyakhto ◽  
S. V. Villevalde ◽  
A. V. Ezhov ◽  
S. A. Zenin ◽  
N. A. Koziolova ◽  
...  
Keyword(s):  
Russian Federation ◽  
Antithrombotic Therapy ◽  
Stroke Risk ◽  
Retention Rate ◽  
Therapy Retention ◽  
The Russian Federation ◽  
The Mean ◽  
Artery Disease ◽  
Dabigatran Therapy

Aim. To analyze clinical characteristics of patients with nonvalvular atrial fibrillation (AF) in the Russian population, enrolled in the GLORIA-AF registry phase 2, depending on the antithrombotic therapy received, and to assess the potential for patient retention with dabigatran during a 2-year follow-up.Material and methods. In the Russian Federation, 408 patients were included in the second phase of GLORIA-AF which is a global prospective observational registry of newly diagnosed patients with AF. The patient characteristics are presented depending on received antithrombotic therapy (dabigatran, factor Xa inhibitors, vitamin K antagonist, antiplatelet agents, or no antithrombotic therapy), with a dabigatran dosing regimen of either 110 mg or 150 mg twice daily. Duration of patient retention on dabigatran therapy was also analyzed during a 2-year follow-up.Results. Of the 405 patients with recently diagnosed nonvalvular AF, 358 (88%) received oral anticoagulants (OAC), and 47 (12%) patients received antiplatelet drugs or received no antithrombotic therapy. Most patients were treated with dabigatran (n=275, 68%), and 75 (19%) patients received vitamin K antagonist. Clinical and demographic characteristics of patients receiving dabigatran were comparable with those in the general group of the Russian patients. The mean age was 63,5 years. The most common comorbidities in Russian patients receiving dabigatran were hypertension (93%), congestive heart failure (57%), coronary artery disease (35%). It is noteworthy that 12% and 10% of patients had a previous myocardial infarction and stroke, respectively. The mean CHA2DS2-VASc score for stroke risk for these patients was 3,2; 88% of patients had a high stroke risk (score of >2). Of the 275 patients with AF who received dabigatran therapy, 164 (60%) patients received dabigatran at the dose of 150 mg twice daily, and 111 (40%) patients received 110 mg twice daily. Dabigatran doses of 110 mg twice daily were more frequently prescribed for female patients aged 65 years or older and patients with a previous coronary events and impaired renal function, who had a higher CHA2DS2-VASc score for stroke risk. There was a higher proportion of AF patients with marked symptoms in the dabigatran 150 mg twice daily group. A median duration of treatment with dabigatran with the initial dosing regimen was 24 months. The estimated dabigatran therapy retention rate was 0,87, 0,81 and 0,73 after 6, 12 and 24 months of follow-up, respectively.Conclusion. In the Russian Federation, patients with newly diagnosed AF who have an increased risk of stroke are more likely to receive OAC therapy, such as direct thrombin inhibitor (dabigatran), compared to the global cohort of the GLORIA AF Registry Program. Patients in the Russian cohort receiving dabigatran differ from the global cohort of patients by greater comorbidity. At the same time, patients receiving reduced doses of dabigatran, both in the Russian Federation and in the global Registry, are characterized by a greater proportion of patients aged >75 years, a higher incidence of previous myocardial infarction, coronary artery disease, heart failure, impaired renal function, higher CHA2DS2-VASc score for stroke risk. The potential dabigatran therapy retention rate after 24 months in the Russian Federation and in the global cohort was high and amounted to about 70%.

scholarly journals Diseases with oral manifestations among adult asthmatics in Finland: a population-based matched cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e053133
Author(s):  
Riikka Lemmetyinen ◽  
Jussi Karjalainen ◽  
Anna But ◽  
Risto Renkonen ◽  
Juha Pekkanen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Proportional Hazards ◽  
Population Based ◽  
Oral Disease ◽  
Matched Cohort ◽  
Oral Diseases ◽  
Adult Asthma ◽  
Drug Reimbursement ◽  
Matched Cohort Study

ObjectivesMany comorbidities are associated with adult asthma and may exacerbate the asthma burden of disease. This study aims to investigate the risk for major oral diseases or oral-manifesting diseases in asthmatic compared with non-asthmatic adults.DesignWe conducted a population-based matched cohort study with a 13.8-year follow-up.SettingA baseline questionnaire was completed by participants in 1997 and follow-up data were extracted from the national hospital discharge registry of the National Institute for Health and Welfare in Finland from 1997 to 2014.ParticipantsA total of 1394 adults with asthma were matched with 2398 adults without asthma based on sex, age and area of residence. Asthmatic adults were identified from the Drug Reimbursement Register of the Finnish Social Insurance Institution based on a special drug reimbursement right resulting from asthma. Participants without asthma were identified from the Population Register.Main outcomes and measuresOral health-related primary diagnoses were retrieved using codes from the International Classification of Diseases, 10th edition and divided into groups of diseases. Cox’s proportional hazards models stratified by matching unit and models matched and adjusted for pack-years, education level and body mass index (when possible) were used to evaluate the matched and further adjusted HRs for diseases comparing asthmatic and non-asthmatic cohorts.ResultsAdult asthma was associated with a higher risk for any oral-manifesting disease (adjusted HR 1.41, 95% CI 1.11 to 1.80), herpes zoster (adjusted HR 6.18, 95% CI 1.21 to 31.6), benign tumours of the oral cavity and pharynx (matched HR 1.94, 95% CI 1.05 to 3.56) and dermatological diseases (pemphigus, pemphigoid, dermatitis herpetiformis, psoriasis and lichen planus, HR 1.67, 95% CI 1.01 to 2.78).ConclusionsIn this study, adult asthmatics experienced a higher risk for a major oral disease or oral-manifesting disease.

Renal replacement therapy in the Russian Federation: A 20-year follow-up

2020 ◽  
pp. 1-6 ◽  
Author(s):  
Kirill Milchakov ◽  
Mikhail Shvetsov ◽  
Evgeniy Shilov ◽  
Ruslan Khalfin ◽  
Nina Rozina ◽  
...  
Keyword(s):  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Russian Federation ◽  
The Russian Federation

scholarly journals ORGANIZATION OF OPHTHALMOLOGICAL CARE FOR THE CHILDREN PRESENTING WITH RETINOPATHY OF PREMATURITY IN THE REPUBLIC OF CRIMEA

2017 ◽  
Vol 12 (4) ◽  
pp. 216-218
Author(s):  
E. Yu Birkun ◽  
S. A Sorokina ◽  
T. A Berezovskaya ◽  
E. I Saidasheva
Keyword(s):  
Retrospective Analysis ◽  
Russian Federation ◽  
Retinopathy Of Prematurity ◽  
Clinical Hospital ◽  
Diagnostic Instruments ◽  
The Crimea ◽  
Instruments And Techniques ◽  
The Russian Federation ◽  
The Republic

Aim. The objective of the present study was to identify the main stages of the organization and the results of the ophthalmological care for the children presenting with retinopathy of prematurity (ROP) in the Republic of Crimea. Material and methods. This retrospective analysis of the results of ophthalmological screening of 2105 prematurely born children, monitoring of 281 children with the early stages of ROP, the laser-assisted treatment of 64 babies undergoing the progression of the disease to its threshold stages and the follow up of the children with ROP in the Crimea during the period from 1999 to 2016 years. All the above patients were nursed and treated in the clinical hospital over the territory of the Crimea and in the perinatal centre of Simferopol. Results. ROP was diagnosed in 281 (26%) of the 2105 prematurely born children. The progression of the disease to the threshold stage was documented in 64 (22.8%) patients within 1 to 12 (mean 3-4) weeks after the identification of the initial stages of active ROP. ROP of the posterior aggressive type developed in 15 children. The duly-timed laser-assisted treatment permitted to prevent the appearance of blindness among the prematurely born children attributable to retinopathy of prematurity. As a results of the implementation of the program for the modernization of the ophthalmological care for the retinopathy of prematurity in the Republic of Crimea it is currently organized and provided in conformity with the relevant normative acts of the Ministry of Health of the Russian Federation. The ophthalmological Department of the Republic of Crimea Children’s Clinical Hospital is equipped with the necessary modern medical and diagnostic instruments and techniques; training of the Crimean ophthalmologists in retinopathy of prematurity and laser-assisted treatment of active retinopathy of prematurity.

scholarly journals Tax Mechanisms to Reduce the Economic Impact of the COVID-19 Pandemic in the Russian Federation and the European Union

2021 ◽  
Vol 16 (7) ◽  
pp. 66-76
Author(s):  
K. A. Ponomareva
Keyword(s):  
Russian Federation ◽  
The European Union ◽  
Global Challenge ◽  
Support Measures ◽  
The Face ◽  
Huge Impact ◽  
The Russian Federation ◽  
National Governments ◽  
The Eu

In 2020, the world has faced with a global challenge – the new coronavirus infection (COVID-19) pandemic, which has had a huge impact on the policies and economies of all states. In the face of severe economic slowdown, most countries have implemented stimulus packages. The paper describes the measures of tax support introduced in the Russian Federation and the EU and highlights the stages of the introduction of these measures. At the first stage, support measures were introduced for citizens and enterprises through both cash payments and a deferral of tax collection, the introduction of temporary benefits and mitigation of the rules for the transfer of losses. The next step was to stimulate the economy, including through tax policy measures.The paper is a continuation of the study, the results of which – an analysis of the measures of the first stage in the OECD and the EU – were published by the author in No. 10, 2020, Journal “Actual Problems of Russian Law.” This paper examines the follow-up measures introduced by national governments, as well as the measures planned to be introduced in the EU. In addition, the analysis of tax support measures developed and introduced in the Russian Federation was carried out.

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