RESEARCH ON CLINICAL MANIFESTATIONS AND AEROBIC BACTERIA OF ACUTE TONSILITIS IN HUE CENTRAL HOSPITAL AND HUE UNIVERSITY HOSPITAL

2012 ◽  
pp. 30-37
Author(s):  
Kim Tri Truong ◽  
Tu The Nguyen ◽  
Lam Phuoc Vo

Objective: To study the paraclinical and clinical mannifestations, aerobic bacteria and antibiogramme of acute tonsilitis. Materials and method: A cross-sectional study was conducted upon 34 patients with acute tonsilitis at Hue Central hospital and of Hue University Hospital. Results: Clinical and paraclinical characteristics: odynophagy 94.1%, tonsillar hyperaemia 88.2%. Having treatment with antibiotics before hospitalization 50%. White blood cells >10-15.109/l (58.8%). Positive bacteria culture is 67.6% in which streptococcus β hemolytic group (A) 25%, streptococcus α hemolytic 25%, hemophilus influenzae 25%. Antibiogramme: Sensitization: gentamycin 100%, cefuroxim 100%, ceftriaxone 93.8%, cefalexin 90.9%, vancomycin 86.7%; Resistance: Tetracyclin 85.7%, erythromycin 69.2%, ofloxacin 42.9%, ampicillin 33.3%, ciprofloxacin 33.3%. Consclusions: The priority of antibiotic prescription for acute tonsilitis should be based on the frequency of bacteria found in bacteria culture and depending on antibiogramme to choose appropriate antibiotics.

2012 ◽  
pp. 85-91
Author(s):  
Kim Tri Truong ◽  
Tu The Nguyen ◽  
Lam Phuoc Vo

Objectives: To identify the paraclinical and clinical mannifestations, aerobic bacteria and antibiogramme of quinsy. Materials and methods: Cross-sectional study was conducted upon 37 patients with quinsy at Hue Central hospital and Hue University Hospital. Results: Clinical and paraclinical symtoms: odynophagy 100%, dysphagy 91.9%. Having treatment with antibiotics before hospitalization 67.6%. White blood cells >15.109/l (54.1%). Positive bacteria culture is 48.6% in which streptococcus α hemolytic 57.9%, staphylococcus aureus 10.5%, streptococcus pneumoniae 10.5%. Antibiogramme: Sensitization: Gentamycin 100%, vancomycin 100%, cefuroxim 100%, ciprofloxacin 80%.Resistance: Erythromycin 60%, ampicillin 41.7%, cefalexin 40%, tetracyclin 40%, ceftriaxon 30.8%.Consclusions: The priority of antibiotic prescription for quinsy should be based on the frequency of bacteria found in bacteria culture and depending on antibiogramme to choose appropriate antibiotics.


2020 ◽  
pp. 15-24
Author(s):  
Nhon Tran Van ◽  
Mai Do Van ◽  
Hien Ha Minh

Background: To survey for evaluation the use of antibiotic for diarrhea treatment on pediatric inpatient in compliance with MOH, WHO or treatment regimen. Objectives: (1) To describe the situation of antibiotic use for diarrhea treatment and (2) to determine factors that affected on indication of antibiotic for pediatric inpatient under 15 years at Kien Giang General Hospital in 2019. Subjects and methods: A cross-sectional study on 251 medical records of pediatric inpatients who treated by one of any drug from 01/2019 to 12/2019. Results: one antibiotic was prescribed in 71.7% in comparison with 17.1% on two antibiotics. The antibiotic prescription was based on the results of blood test including examinations of white blood cells (WBC), the percentage of neutrophils (Neu%) and/or C-reactive protein (CRP) (59.4%), stool with white blood cells and/or red blood cells (1.6%), high fever without causes (27.9%), watery stool (86.3%), loose stool with blood (100%), loose stool (97.9%). The most used antibiotics are ceftriaxone (53.4%), ciprofloxacin (12.4%). Duration of antibiotic use is 5 days in median. Conclusion: The rate of antibiotic prescription that met MOH and WHO guidelines was 88.3% in comparison with 11.7% of non-conformance. The compliance prescriptions based on antibiogram were 77.8%, non-compliance were 22.5%. The compliance dosage refered to guideline was 86.4%, non-conpliance was 2.4%. The duration of hospitalization and neutrophil are factors that affected the use of antibiotics (p < 0.05). Keywords: diarrhea, pediatric inpatient, antibiotic, Pediatrics-Kien Giang General Hospital


Author(s):  
Gunta Laizāne ◽  
Anda Ķīvīte ◽  
Ilze Grope ◽  
Liene Smane ◽  
Edvīns Miklaševics ◽  
...  

Abstract In developed and developing countries, most cases of acute gastroenteritis in children are caused by viruses, and rotaviruses are known as the leading cause. The aim of our study was to estimate the main circulating serotypes of rotavirus before the introduction of routine immunisation in Latvia, and to search for their possible correlation with clinical symptoms and circulating genotypes. A cross-sectional study was carried out among children who had been hospitalised in the Children’s Clinical University Hospital from April 2013 to December 2015. Genotyping was done for 462 stool samples. Among G/P combinations, the most predominant genotypes were G4P[8] (61.3%), G9P[8] (12.4%) and G2P[4] (10.0%) in children of age < 5 years, G4P[8] (45.5%), G2P[4] (18.2%), G9P[8], G3P[8], and G1P[8] (9.1%) in children of age > 5 years. There was a statistically significant correlation (p < 0.05) between clinical signs (vomiting, dehydration, chronic diseases) and G1P[8] and G8P[8] genotypes. Infants infected with genotype G4P[4] had a statistically significant negative correlation with severity of acute gastroenteritis episodes (p < 0.05). We detected nine different rotavirus G genotypes, and two different P genotypes. G4P[8], G9P[8], and G2P[8] were predominant. We observed correlation between the dominant genotypes and clinical manifestations of rotavirus infection.


2017 ◽  
pp. 190-196
Author(s):  
Thi Anh Ngoc Le ◽  
Nu Xuan Thanh Le ◽  
Thi Nam Lien Nguyen ◽  
Viet Quynh Tram Ngo ◽  
Santon Antonella ◽  
...  

Introduction: Acinetobacter baumannii resistant to carbapenem is the most common cause of nosocomial infection, they are recognized as one of the most difficult to control and treat resistant agents. A. baumannii is the most important member of A. calcoaceticus- A. baumannii complex (ACB complex), which are closely related genetically then biochemical test systems are not able to identify unambiguously genomic species. Objective: To identify species of Acinetobacter sp. strains of ACB complex and sequence types of A. baumannii strains. Methods: Cross- sectional study. The subjects were 90 strains of ACB complex isolated and identified by biochemical methods at Hue University Hospital (UH) and Hue Central Hospital (CH). Performing the multiplex PCRs on the target gene gyrB and sequencing rpoB gene to identify species. Determining of antibiotic resistance by Kirby-Bauer method. Multi Locus Sequence Type (MLST) method was performed for 24 strains of A. baumannii to identify sequence types. Results: Acinetobacter sp. were identified as A.bau-mannii (85.6%), A. nosocomialis (11.11%) and A. pittii (3.33%). All strains of ACB complex were sensitive to colistin and resistant to cefotaxime, amikacin. More than 90% of A.baumannii strains were resistant to carbapenem. Eleven sequence types (STs) of A.baumannii strains were identified; two of them were news (ST1463 and ST1464) and seven STs belonged to the Clonal Complex 92 (CC92), the most globally distributed clones; the ST795, ST797 and ST1463 are circulating in both of hospitals. Conclusion: Combining multiplex PCRs on the target gene gyrB and sequencing rpoB gene have shown to be adequate for Acinetobacter sp.identification. MLST identified 11 sequence types from 24 A.baumannii isolates at two hospital in Hue. Key words: ACB complex, Acinetobacter baumannii, MLST


Author(s):  
Ome Kulsoom

Background: Caesarean Sections (CS), significantly on the rise worldwide, have been found frequently complicated with the presence of a scar at the site of CS. It is associated with various gynecological problems like postmenstrual spotting, infertility, miscarriage, and uterine rupture. The objective of this study was to determine the frequency of CS scar defects and associated gynaecological symptoms. Methods: This cross-sectional study was conducted at the Department of Obstetrics and Gynaecology, Ziauddin University Hospital Karachi from October 1st, 2017 to March 1st, 2018. A total of 162 patients’ (aged 20-40 years) were included, with CS history (elective or emergency) and complaints of chronic pelvic pain, infertility or menstrual irregularities, after an informed consent. Demographic details and medical history were recorded on performa. Chi-square was used to establish association between categorical variable such presence of scar defect, clinical symptoms and the shape of the defect. Results: Out of 162 patients, 86(53.1%) had one and 76(46.9%) had more than one caesarean scar. Majority of the patients 97(59.9%) were found to have scar defect (NICHE) present while in 65 (40.1%) patients had no caesarean scar defect. Regarding menstrual cycle, 58(35.8%) had heavy bleeding, 39(24.1%) continuous bleeding, and 27 (16%) irregular cycle. Significant association (p˂0.05) was found between menstrual irregularity, pelvic pain, infertility and scar defects. Different shapes of scar (niche) were noted triangular 46(28.4%) droplet 26(16%), oval and others such as rectangular and inclusion cyst on ultrasonographic . Conclusion: Multiple Caesarean sections are predisposing factors for Caesarean scar defects. Menstrual irregularity, pelvic pain, infertility and scar defects were found significantly associated with Caesarean sections (p˂0.05).


Author(s):  
Manal M. Anwar ◽  
Ahmed E. Arafa ◽  
Dalia S. Morgan ◽  
Khaled K. Mohamed

Background: Estimate the prevalence of vitamin D deficiency among patients diagnosed with chronic cholestasis and investigates the association between their clinical manifestations and lab results of 25(OH) D levels.Methods: A cross sectional study of 50 patients aged > 3 months up to 18 years, who had medical care in the Beni-Suef University hospital, Beni-Suef governorate, Egypt. All patients were fully investigated including routine labs in addition to 25- [OH] D levels and dual energy X-ray absorptiometry (DXA).Results: Mean age was 6.5±4.5 years. Mean serum 25 (OH) D levels was 37.9±28.2; 30% of patients had 25 (OH) D <20 ng/ml and 26% had 25 (OH) D 20-<30 ng/ml. Low BMD was diagnosed in 73.1% of patients. The spine DXA BMD ranged between -5.4 and -1.4 (-2.9±0.9 Z-scores). A delayed milestone was reported in 32% of patients, and 56% had signs of rickets.Conclusions: Deficiency of Vitamin D, signs of rickets and osteoporosis were evident in chronic cholestasis patients. No statistical significance was detected between 25- D [OH] levels and clinical, laboratory and radiological findings.


2012 ◽  
pp. 46-52
Author(s):  
Kim Tri Truong ◽  
Tu The Nguyen ◽  
Lam Phuoc Vo

Objectives: Researching on paraclinical and clinical characteristic, aerobic bacterial and antibiotic graph of chronic tonsilitis. Materials and methods: 61 tonsilitis patients were studied by crossing, descriptive- statistical and clinic intervention method. Results: The tonsils appear small sized in 15 and more years old group 83.3%, hypertrophy tonsilitis in 31 and younger years old group 83.6%. Treatment with antibiotics outside hospital 4.9%. White blood cells £10.109/l (88.5%). Positive bacterial rate 65.6%. Bacterial races are often found is hemophilus influenza 27.7%, staphylococcus aureus 17.0%. Antibiotic graph: bacterial sensitize to gentamycin 94.1%, cefalexin 93.8%, vancomycin 91.7%, ciprofloxacin 90.5%, ofloxacin 90.0%, ceftriaxone 89.3%, cefuroxim 83.3%, resist to tetracyclin 46.2%, ampicillin 38.1%, erythromycin 27.3%. Consclusions: Depending on frequencies bacterial races are often found in chronic tonsilitis afterwards considering carefully designation using antibiotic and bacterial are found in to choose suitable antibiotic.


2020 ◽  
Vol 7 (4) ◽  
pp. 143-146
Author(s):  
Dr. Dhananjay Wagh ◽  
Dr. Suma Wagh ◽  
Dr. Shikha Krishnani

COVID-19 is a new-age pandemic which has spread ferociously all over the world in a matter of a few months having worldwide humanitarian and economic repercussions. HRCT has become the mainstay of radiological investigations in this pandemic and often shoed diagnostic accuracy before the onset of clinical manifestations. Men are more predisposed for fatal outcomes in other SARS virus infections.1 In a study by Karlberg et al, males had a significantly (p < 0.0001) higher case fatality rate than females did, 21.9 percent versus 13.2 percent after adjustment for age.  Studies found that the severity of the illness was more and clearance of SARS-CoV-2 virus was less in males as compared to females.2 Hence it is of utmost importance to study the pattern of lung involvement on HRCT to aid the clinician in starting the treatment at the earliest, even before the symptoms manifest. Thus this study was conducted to look for specific and also unusual patterns of radiological findings of COVID-19 pneumonia.


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