scholarly journals Collagenofibrotic Glomerulopathy: Report a Rare Case

2020 ◽  
Vol 23 (6) ◽  
pp. 409-411
Author(s):  
Rakesh Agarwal ◽  
Rashmi Baid ◽  
Jotideb Mukhopadhyay
Keyword(s):  
Rare Case ◽  
Collagen Type ◽  
Villous Atrophy ◽  
Renal Involvement ◽  
Rare Clinical Entity ◽  
Rare Entity ◽  
Adult Onset ◽  
Collagen Type Iii ◽  
Procollagen Iii Peptide ◽  
Procollagen Iii

Collagenofibrotic glomerulopathy is a rare clinical entity with fewer than 40 cases reported worldwide. We describe a case of adult onset nephrotic syndrome with partial villous atrophy of the intestine who was diagnosed with this rare entity. Collagenofibrotic glomerulopathy is characterized by subendothelial and mesangial collagen type III deposition and increased procollagen III peptide levels. Extra renal involvement has been described in the form of hypertension, anemia and microangiopathic hemolytic anemia but villous atrophy has not been associated with this condition so far, possibly reflecting the paucity of literature. We describe this case and review the condition in this report.

scholarly journals Pediatric Infraorbital Nerve Schwannoma: A Rare Clinical Entity

2011 ◽  
Vol 2 (1) ◽  
pp. 73-75
Author(s):  
GA Raviraj ◽  
Thomas Rony ◽  
GA Dhanraj ◽  
Vishal US Rao
Keyword(s):  
Differential Diagnosis ◽  
Rare Case ◽  
Infraorbital Nerve ◽  
Age Group ◽  
Rare Clinical Entity ◽  
Pediatric Age ◽  
Rare Entity ◽  
Nerve Sheath Tumors ◽  
Nerve Sheath ◽  
The Right

ABSTRACT This report elaborates a rare case of infraorbital nerve Schwannoma in an 8-year-old boy who presented with the recurrent progressively increasing swelling over the right cheek following initial treatment. The mass was excised surgically via a facial approach. Infraorbital nerve sheath tumors occurring in the pediatric age are rare and can be often mistaken for infectious causes in this age group. Surgery remains the mainstay of treatment in these tumors. Early diagnosis and prompt surgical treatment can serve to minimize the treatment related morbidity arising from multiple interventions while avoiding undue apprehension. Pediatric infraorbital schwannomas, although a rare entity, should be considered in the differential diagnosis of long standing pediatric facial swellings.

scholarly journals Ossification of the bilateral Achilles tendon: a rare entity

2015 ◽  
Vol 4 (9) ◽  
pp. 205846011559918 ◽  
Author(s):  
Abhishek J Arora ◽  
Richa Arora
Keyword(s):  
Infectious Diseases ◽  
Achilles Tendon ◽  
Female Patient ◽  
Genetic Predisposition ◽  
Rare Case ◽  
Predisposing Factors ◽  
Clinical Entity ◽  
Rare Clinical Entity ◽  
Rare Entity ◽  
History Of

Ossification of the Achilles tendon is a rare clinical entity comprising of one or more segments of variable sized ossified masses in the fibrocartilaginous substance of the tendon. The etiology of ossification of the Achilles tendon is multifactorial with recurrent trauma and surgery comprising major predisposing factors, with others being metabolic, systemic, and infectious diseases. The possibility of a genetic predisposition towards this entity has also been raised, but has not yet been proven. We present a rare case of ossification of the bilateral Achilles tendons without any history of trauma or surgery in a 48-year-old female patient.

scholarly journals ADULT ONSET HENOCH: SCHONLEIN PURPURA – AN UNUSUAL PRESENTATION

2017 ◽  
Vol 10 (10) ◽  
pp. 2
Author(s):  
Srujith Chandrakanti ◽  
Oshin Mantro ◽  
Jagadeesan Mohanan ◽  
Mervin Kayipirambil Soman ◽  
Prasanna Karthik Suthakaran ◽  
...  
Keyword(s):  
Rare Case ◽  
Early Recognition ◽  
Leukocytoclastic Vasculitis ◽  
Renal Involvement ◽  
Unusual Presentation ◽  
Organ Involvement ◽  
Adult Onset ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

  Henoch–Schonlein purpura (HSP) is a common leukocytoclastic vasculitis seen in children. However, it is uncommon in adults. HSP is characterized by the classic tetrad of non-thrombocytopenic palpable purpura, arthritis or arthralgias, gastrointestinal, and renal involvement. We report a rare case of adult onset HSP with multi-organ involvement. Early recognition of multi-organ involvement is very important, especially in adults.

scholarly journals Data mining-based study of collagen type III alpha 1 (COL3A1) prognostic value and immune exploration in pan-cancer

Bioengineered ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 3634-3646
Author(s):  
Hanyu Zhang ◽  
Cheng Ding ◽  
Yatong Li ◽  
Cheng Xing ◽  
Shunda Wang ◽  
...  
Keyword(s):  
Data Mining ◽  
Prognostic Value ◽  
Collagen Type ◽  
Collagen Type Iii ◽  
Type Iii ◽  
Pan Cancer

scholarly journals Cystic papillary adenoma of the seminal vesicle

BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
B. Heijkoop ◽  
D. Bolton ◽  
D. Katz ◽  
Andrew Ryan ◽  
J. Epstein ◽  
...  
Keyword(s):  
Seminal Vesicle ◽  
Rare Case ◽  
Groin Pain ◽  
Iliac Fossa ◽  
Papillary Adenoma ◽  
Rare Entity ◽  
Macroscopic Haematuria ◽  
Case Presentation ◽  
Adjacent Organ ◽  
Epithelial Tumours

Abstract Background Primary Seminal Vesicle (SV) tumours are a rare entity, with most SV masses representing invasion of the SV by malignancy originating in an adjacent organ, most often the prostate. Previously reported primary SV epithelial tumours have included adenocarcinoma and cystadenoma, with limited prior reports of inracystic papillary structures. Case presentation A 35-year-old male presented with azoospermia, intermittent macroscopic haematuria, and mild right iliac fossa and groin pain. A papillary appearing seminal vesicle mass was found on imaging and seminal vesicoscopy. The mass was robotically excised with diagnosis of benign cystic papillary adenoma made. Conclusion In this manuscript we describe a rare case of a benign cystic papillary adenoma of the seminal vesicle, a unique histological entity differentiated from cystadenoma of the Seminal Vesicle by its papillary component.

scholarly journals Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Neel I. Nissen ◽  
Stephanie Kehlet ◽  
Mogens K. Boisen ◽  
Maria Liljefors ◽  
Christina Jensen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Collagen Type ◽  
Performance Status ◽  
Drug Uptake ◽  
Collagen Type Iii ◽  
Serum Samples ◽  
Type Iii ◽  
Poor Treatment ◽  
And Performance

AbstractA desmoplastic colorectal cancer stroma, characterized by excess turnover of the cancer-associated fibroblast derived collagens type III and VI, can lead to reduced drug-uptake and poor treatment response. We investigated the association between biomarkers of collagen type III and VI and overall survival (OS) in patients with metastatic colorectal cancer (mCRC). Serum samples were collected from 252 patients with mCRC prior to treatment with bevacizumab and chemotherapy. Serum concentrations of biomarkers reflecting formation of collagen type III (PRO-C3) and VI (PRO-C6) and degradation of collagen type VI (C6M and C6Mα3) were determined by ELISA. The biomarkers were evaluated for associations with OS, individually, combined, and after adjusting for carcinoembryonic antigen (CEA), lactate dehydrogenase (LDH) and performance status (PS). High baseline levels (> median) of each collagen biomarker were significantly associated with shorter OS (PRO-C3: HR = 2.0, 95%CI = 1.54–2.63; PRO-C6: HR = 1.6, 95%CI = 1.24–2.11; C6M: HR = 1.4, 95%CI = 1.05–1.78; C6Mα3: HR = 1.6, 95%CI = 1.16–2.07). PRO-C3 and PRO-C6 remained significant after adjustment for CEA, LDH and PS. Weak correlations were seen between the collagen biomarkers (r = 0.03–0.59) and combining all improved prognostic capacity (HR = 3.6, 95%CI = 2.30–5.76). Collagen biomarkers were predictive of shorter OS in patients with mCRC. This supports that collagen- and CAF biology is important in CRC.

scholarly journals A Rare Case of Localised Isolated Penile Fournier’s Gangrene and a Short Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Antonios Katsimantas ◽  
Nikolaos Ferakis ◽  
Panagiotis Skandalakis ◽  
Dimitrios Filippou
Keyword(s):  
Enterococcus Faecalis ◽  
Fluid Resuscitation ◽  
Rare Case ◽  
Short Review ◽  
Fournier’S Gangrene ◽  
Rare Clinical Entity ◽  
Review Of The Literature ◽  
Fournier's Gangrene ◽  
Surgical Exploration ◽  
Prevotella Melaninogenica

Penile Fournier’s gangrene (FG) is very rare clinical entity, which is also known as penile necrotizing fasciitis or wet gangrene of the penis. It is associated with increased morbidity and mortality and in the majority of the described cases it affects not only penis but also the adjacent organs and tissues (e.g., bladder, muscles, rectum, testis, and scrotum). We report a rare case of a previously healthy 68-year-old male, who presented with acute isolated penile Fournier’s gangrene. Pus culture was identified with pathogens Enterococcus faecalis, Streptococcus gordonii, and Prevotella melaninogenica. Prompt surgical exploration, fluid resuscitation, antibiotic treatment, and diligent postoperative care are the cornerstone in the successful treatment of this emergency with high mortality.

Two Brothers in One Chinese Family With Collagen Type III Glomerulopathy

2007 ◽  
Vol 50 (6) ◽  
pp. 1037-1042 ◽  
Author(s):  
Nan Chen ◽  
Xiaoxia Pan ◽  
Yaowen Xu ◽  
Zhaohui Wang ◽  
Hao Shi ◽  
...  
Keyword(s):  
Collagen Type ◽  
Chinese Family ◽  
Collagen Type Iii ◽  
Type Iii ◽  
Collagen Type Iii Glomerulopathy
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