scholarly journals Potential Benefits of Sexting among Long-term Monogamous Romantic Partners

2022 ◽  
pp. 30-38
Author(s):  
Jia Jian Tin ◽  
Victoria Williams ◽  
Samuel Montano
Keyword(s):  
Romantic Partners ◽  
Potential Benefits

scholarly journals We’re Not That Choosy: Emerging Evidence of a Progression Bias in Romantic Relationships

2021 ◽  
pp. 108886832110258
Author(s):  
Samantha Joel ◽  
Geoff MacDonald
Keyword(s):  
Romantic Relationships ◽  
Mate Selection ◽  
Theoretical Models ◽  
Romantic Partners ◽  
Test Phase ◽  
Relationship Development ◽  
Cultural Narrative ◽  
Relationship Initiation ◽  
Relationship Decisions

Dating is widely thought of as a test phase for romantic relationships, during which new romantic partners carefully evaluate each other for long-term fit. However, this cultural narrative assumes that people are well equipped to reject poorly suited partners. In this article, we argue that humans are biased toward pro-relationship decisions—decisions that favor the initiation, advancement, and maintenance of romantic relationships. We first review evidence for a progression bias in the context of relationship initiation, investment, and breakup decisions. We next consider possible theoretical underpinnings—both evolutionary and cultural—that may explain why getting into a relationship is often easier than getting out of one, and why being in a less desirable relationship is often preferred over being in no relationship at all. We discuss potential boundary conditions that the phenomenon may have, as well as its implications for existing theoretical models of mate selection and relationship development.

scholarly journals Gene Therapy in Hemophilia: Recent Advances

2021 ◽  
Vol 22 (14) ◽  
pp. 7647
Author(s):  
E. Carlos Rodríguez-Merchán ◽  
Juan Andres De Pablo-Moreno ◽  
Antonio Liras
Keyword(s):  
Gene Therapy ◽  
Adverse Events ◽  
Factor Viii ◽  
Coagulation Factor ◽  
Cost Savings ◽  
Factor Ix ◽  
Clotting Factors ◽  
Advanced Therapies ◽  
Potential Benefits

Hemophilia is a monogenic mutational disease affecting coagulation factor VIII or factor IX genes. The palliative treatment of choice is based on the use of safe and effective recombinant clotting factors. Advanced therapies will be curative, ensuring stable and durable concentrations of the defective circulating factor. Results have so far been encouraging in terms of levels and times of expression using mainly adeno-associated vectors. However, these therapies are associated with immunogenicity and hepatotoxicity. Optimizing the vector serotypes and the transgene (variants) will boost clotting efficacy, thus increasing the viability of these protocols. It is essential that both physicians and patients be informed about the potential benefits and risks of the new therapies, and a register of gene therapy patients be kept with information of the efficacy and long-term adverse events associated with the treatments administered. In the context of hemophilia, gene therapy may result in (particularly indirect) cost savings and in a more equitable allocation of treatments. In the case of hemophilia A, further research is needed into how to effectively package the large factor VIII gene into the vector; and in the case of hemophilia B, the priority should be to optimize both the vector serotype, reducing its immunogenicity and hepatotoxicity, and the transgene, boosting its clotting efficacy so as to minimize the amount of vector administered and decrease the incidence of adverse events without compromising the efficacy of the protein expressed.

scholarly journals Genetic Consequences of Fence Confinement in a Population of White-Tailed Deer

Diversity ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 126
Author(s):  
Emily K. Latch ◽  
Kenneth L. Gee ◽  
Stephen L. Webb ◽  
Rodney L. Honeycutt ◽  
Randy W. DeYoung ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Mitochondrial Dna ◽  
Wildlife Management ◽  
Field Observations ◽  
Adaptive Potential ◽  
Population Isolation ◽  
Potential Benefits ◽  
Wildlife Populations ◽  
Mtdna Diversity

Fencing wildlife populations can aid wildlife management goals, but potential benefits may not always outweigh costs of confinement. Population isolation can erode genetic diversity and lead to the accumulation of inbreeding, reducing viability and limiting adaptive potential. We used microsatellite and mitochondrial DNA data collected from 640 white-tailed deer confined within a 1184 ha fence to quantify changes in genetic diversity and inbreeding over the first 12 years of confinement. Genetic diversity was sustained over the course of the study, remaining comparable to unconfined white-tailed deer populations. Uneroded genetic diversity suggests that genetic drift is mitigated by a low level of gene flow, which supports field observations that the fence is not completely impermeable. In year 9 of the study, we observed an unexpected influx of mtDNA diversity and drop in inbreeding as measured by FIS. A male harvest restriction imposed that year increased male survival, and more diverse mating may have contributed to the inbreeding reduction and temporary genetic diversity boost we observed. These data add to our understanding of the long-term impacts of fences on wildlife, but also highlight the importance of continued monitoring of confined populations.

scholarly journals Consensus for the General Use of Equine Water Treadmills for Healthy Horses

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 305
Author(s):  
Kathryn Nankervis ◽  
Carolyne Tranquille ◽  
Persephone McCrae ◽  
Jessica York ◽  
Morgan Lashley ◽  
...  
Keyword(s):  
Working Group ◽  
Best Practice ◽  
Treadmill Exercise ◽  
Good Practice ◽  
Belt Speed ◽  
Research Programmes ◽  
Potential Benefits ◽  
Water Treadmill ◽  
Selection Of

Water treadmill exercise has become popular in recent years for the training and rehabilitation of equine athletes. In 2019, an equine hydrotherapy working group was formed to establish what was commonly considered to be best practice in the use of the modality. This article describes the process by which general guidelines for the application of water treadmill exercise in training and rehabilitation programmes were produced by the working group. The guidelines describe the consensus reached to date on (1) the potential benefits of water treadmill exercise, (2) general good practice in water treadmill exercise, (3) introduction of horses to the exercise, (4) factors influencing selection of belt speed, water depth and duration of exercise, and (5) monitoring movement on the water treadmill. The long-term goal is to reach a consensus on the optimal use of the modality within a training or rehabilitation programme. Collaboration between clinicians, researchers and experienced users is needed to develop research programmes and further guidelines regarding the most appropriate application of the modality for specific veterinary conditions.

Developing twinning cattle for commercial production

2008 ◽  
Vol 48 (7) ◽  
pp. 930 ◽  
Author(s):  
L. J. Cummins ◽  
C. A. Morris ◽  
B. W. Kirkpatrick
Keyword(s):  
United States ◽  
Production Systems ◽  
The United States ◽  
Research Centre ◽  
Commercial Application ◽  
Term Selection ◽  
Calf Survival ◽  
Potential Benefits ◽  
Meat Animal

Long-term selection programs in the United States and New Zealand have developed twinning herds. In Nebraska, the United States Meat Animal Research Centre population had a calving rate of 1.56 per parturition in 2004. They have shown that the location of ovulation has an important effect on the success of pregnancy and that ovulations ≥3 are probably undesirable. These cattle have issues associated with calving difficulty and calf survival, which present challenges for commercial application. Intensive management using existing technology and/or future genetic improvement to address these traits are required to realise the potential benefits to beef production systems.

Does a Multicomponent Exercise Program Improve Physical Fitness in Older Adults? Findings From a 5-Year Longitudinal Study

2021 ◽  
pp. 1-8
Author(s):  
Andréa Kruger Gonçalves ◽  
Eliane Mattana Griebler ◽  
Wagner Albo da Silva ◽  
Débora Pastoriza Sant´Helena ◽  
Priscilla Cardoso da Silva ◽  
...  
Keyword(s):  
Older Adults ◽  
Physical Fitness ◽  
Cardiorespiratory Fitness ◽  
Upper Limb ◽  
Exercise Program ◽  
Potential Benefits ◽  
Multicomponent Program ◽  
Post Hoc

The objective was to assess the physical fitness of older adults participating in a 5-year multicomponent exercise program. The sample consisted of 138 older adults aged 60–93 years (70.4 ± 7.8 years) evaluated with the Senior Fitness Test (muscle strength, flexibility, balance, and cardiorespiratory fitness). The multicomponent program was carried out between the months of March and November of each year. Data were analyzed using generalized estimating equations (factor year: Year 1, Year 2, Year 3, Year 4, and Year 5; factor time: pretest and posttest) with Bonferroni’s post hoc test. Participation in the multicomponent exercise program for 5 years (baseline pretest Year 1 and follow-up Year 5) improved lower and upper limb strength, lower limb flexibility, and balance and cardiorespiratory fitness, while upper limb flexibility was maintained. Year-by-year analysis revealed variable patterns for each fitness parameter. The results of this study show the potential benefits of implementing a long-term community-based exercise program.

scholarly journals Monitor - an information system for improved municipal environmental management

2019 ◽  
pp. 105-111
Author(s):  
Björn Frostell
Keyword(s):  
Information System ◽  
Research Effort ◽  
Joint Research ◽  
New Information ◽  
Environmental Information System ◽  
Potential Benefits ◽  
State Of The Environment ◽  
The City ◽  
Monitor Data

MONITOR is a joint research effort between a number of research institutions and the city of Stockholm. It aims at developing an environmental information system based on (i) accounlings of flows and stocks of materials and energy (environmental pressure) as well as describing the (ii) state of the environment and the (iii ) environmental impact in an integrated way. In MONITOR, data from existing environmental monitoring in Stockholm is integrated with new information on material flows and stocks. A first prototype, illustrating the potential benefits of MONITOR has been developed. A long-term goal is to develop a tool for an improved economising of materials and energy in the Stockholm region. In the paper, the MONITOR programme is presented as well as initial practical approaches to the work.

Prevalence and Adaptive Impact of Introgression

2021 ◽  
Vol 55 (1) ◽  
Author(s):  
Nathaniel B. Edelman ◽  
James Mallet
Keyword(s):  
Genetic Variation ◽  
Adaptive Evolution ◽  
Genetic Variants ◽  
Genomic Data ◽  
Annual Review ◽  
Publication Date ◽  
Adaptive Introgression ◽  
Changing Environments ◽  
Potential Benefits

Alleles that introgressed between species can influence the evolutionary and ecological fate of species exposed to novel environments. Hybrid offspring of different species are often unfit, and yet it has long been argued that introgression can be a potent force in evolution, especially in plants. Over the last two decades, genomic data have increasingly provided evidence that introgression is a critically important source of genetic variation and that this additional variation can be useful in adaptive evolution of both animals and plants. Here, we review factors that influence the probability that foreign genetic variants provide long-term benefits (so-called adaptive introgression) and discuss their potential benefits. We find that introgression plays an important role in adaptive evolution, particularly when a species is far from its fitness optimum, such as when they expand their range or are subject to changing environments. Expected final online publication date for the Annual Review of Genetics, Volume 55 is November 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Changes in global and relationship-specific attachment working models

2022 ◽  
pp. 026540752110514
Author(s):  
Keely A. Dugan ◽  
R. Chris Fraley ◽  
Omri Gillath ◽  
Pascal R. Deboeck
Keyword(s):  
Online Survey ◽  
Romantic Partners ◽  
Latent Growth ◽  
Short Term ◽  
Working Models ◽  
Long Run ◽  
Curve Modeling ◽  
Median Test ◽  
As Relationship

Attachment theorists suggest that people construct a number of distinct working models throughout life. People develop global working models, which reflect their expectations and beliefs concerning relationships in general, as well as relationship-specific working models of close others—their mothers, fathers, romantic partners, and friends. The present research investigated the interplay of these different working models over time. We analyzed longitudinal data collected from 4,904 adults (mean age = 35.24 years; SD = 11.63) who completed between 3 and 24 online survey assessments (median test–retest interval = 35 days). Using latent growth curve modeling, we examined the associations among both long-term changes and short-term fluctuations in participants’ working models. Our findings suggest that different working models not only change together over the long run, but also exhibit co-occurring, short-term fluctuations. This was true concerning the associations between global and relationship-specific models as well as among different relationship-specific models.

Palliative Care

2015 ◽  
pp. 105-123
Author(s):  
May Hua
Keyword(s):  
Quality Of Life ◽  
Palliative Care ◽  
Intensive Care ◽  
Critical Illness ◽  
Serious Illness ◽  
Surgical Units ◽  
Potential Benefits

Palliative care is a specialty of medicine that focuses on improving quality of life for patients with serious illness and their families. As the limitations of intensive care and the long-term sequelae of critical illness continue to be delimited, the role of palliative care for patients that are unable to achieve their original goals of care, as well as for survivors of critical illness, is changing and expanding. The purpose of this chapter is to introduce readers to the specialty of palliative care and its potential benefits for critically ill patients, and to present some of the issues related to the delivery of palliative care in surgical units.

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