scholarly journals Relationship between platelet indices and lipid status in chronic hookah consumption

2021 ◽  
Keyword(s):  
Platelet Count ◽  
Total Cholesterol ◽  
Negative Correlation ◽  
Complete Blood Count ◽  
Hdl Cholesterol ◽  
Significant Negative Correlation ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Platelet Indices

Hookah smoking is a growing trend, both in the world and in Bosnia and Herzegovina. The aim of this study was to determine the value of platelet indices in hookah smokers and find out associations with lipid profile. Cross-sectional study included 60 students (30 chronic hookah smokers and 30 non-smokers). The complete blood count (erythrocytes, leukocytes, platelets, hemoglobin, hematocrit, erythrocyte and platelet indices), lipid parameters (total cholesterol, triglycerides, LDL-C, HDL-C) were determined. The platelet count, mean platelet volume and MPV/Platelets ratio were statistically significantly higher in chronic hookah consumers in the student population than in the control group (p <0.001). In addition, platelet count was in significant positive correlation with values of total cholesterol, LDL-C and negative correlation with value of HDL-C, while there was a significant negative correlation between mean platelets volume, and MPV/Platelets ratio with HDL cholesterol levels in chronic hookah smokers (p <0.05). These findings suggest that chronic hookah consumption could be associated with the development of atherosclerotic changes in blood vessels, which could lead to the development of long-term consequences on the cardiovascular system's function.

scholarly journals Platelet count can predict the grade of esophageal varices in cirrhotic patients: a cross-sectional study

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 101
Author(s):  
Anum Afsar ◽  
Muhammad Nadeem ◽  
Syed Asim Ali Shah ◽  
Huma Hussain ◽  
Aysha Rani ◽  
...  
Keyword(s):  
Platelet Count ◽  
Negative Correlation ◽  
Esophageal Varices ◽  
Significant Negative Correlation ◽  
Cross Sectional Study ◽  
Variceal Hemorrhage ◽  
Sectional Study ◽  
Cross Sectional ◽  
Grade Ii ◽  
Cirrhotic Patients

Background: Bleeding from esophageal varices is a life-threatening complication in cirrhosis. Screening endoscopy is recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage, but this is an invasive procedure and has limitations. Therefore, thrombocytopenia has been proposed to predict the existence and grade of esophageal varices. The aim of the current study was to determine a correlation between platelet count and grades of esophageal varices in patients with liver cirrhosis. Methods: This cross-sectional study was conducted at the POF Hospital, Wah Cantt from 1st October, 2017 to 30th May, 2018. Newly diagnosed cases of cirrhosis having varices of any grade on endoscopy were included. Endoscopic findings of patients were standardized using Paquet grading system. On the basis of platelet count, patients were divided into four subgroups. Platelet count groups were correlated with grading of esophageal varices using Spearman rank correlations. Chi Square test was used to see association between the platelet count and grade of esophageal varices. Results: 110 patients were included in the study, 55.5% (n=61) were male. Mean age of the patients was 59.89±9.01 years. Platelet count was <50,000/uL in 35.5% patients, 50,000-99,000/uL in 26.4%, 100,000-150000 in 12.7%, and >150,000/uL in 25.5% patients. Grade I esophageal varices were found in 23.6% of patients, whereas grade II, III and IV were found in 24.5%, 33.6% and 18.2% of patients, respectively. Mean platelet count was 213884.62/mm3 in patients with grade I varices, whereas it was 119518.52/mm3, 58386.49/mm3 and 21600.00/mm3 in patients with grade II, III and IV varices, respectively (p=<0.0001). A significant negative correlation between platelet count and grades of esophageal varices was found (p<0.001). Conclusion: Platelet count can predict the grade of esophageal varices in cirrhotic patients. There is significant negative correlation between platelet count and grades of esophageal varices.

scholarly journals Correlation of Platelet Count and Hematocrit Levels to the Severity of Dengue Hemmoraghic Fever Patients at RSD dr. Soebandi Jember

2021 ◽  
Vol 7 (3) ◽  
pp. 156
Author(s):  
Salma Naqiyyah Tirtadevi ◽  
Rini Riyanti ◽  
Desie Dwi Wisudanti
Keyword(s):  
Platelet Count ◽  
Negative Correlation ◽  
Predictive Value ◽  
Medical Records ◽  
Secondary Data ◽  
Significant Negative Correlation ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Major Health

Dengue hemorraghic fever (DHF) is an infectious disease caused by the dengue virus and It is still be a major health problem in Southeast Asia, especially in Indonesia. Kabupaten Jember is still categorized as a dengue endemic area with its disease development expanding from year to year. This study aims to determine the correlation of platelet count and hematocrit levels to the severity of DHF patients at RSD dr. Soebandi Jember, as well as knowing whether the platelet count and hematocrit levels can be used as a predictive value for the severity of DHF patients at RSD dr. Soebandi Jember. This study used an observational analytic study with a cross-sectional study design. The data of this study used secondary data from the medical records of DHF patients at RSD dr. Soebandi Jember. The results of this study with a total of 68 samples showed that there was a significant negative correlation between the platelet count to the severity of DHF patients (p = 0,000, r = -0,487). The hematocrit levels showed an insignificant and negative correlation to the severity of DHF patients (p = 0,658, r = -0,055). The platelet count can be used as a predictive value for the severity of DHF patients. Keywords: DHF, platelet count, hematocrit levels, severity of DHF patients  

scholarly journals Platelet count can predict the grade of esophageal varices in cirrhotic patients: a cross-sectional study

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 101
Author(s):  
Anum Afsar ◽  
Muhammad Nadeem ◽  
Syed Asim Ali Shah ◽  
Huma Hussain ◽  
Aysha Rani ◽  
...  
Keyword(s):  
Platelet Count ◽  
Negative Correlation ◽  
Esophageal Varices ◽  
Significant Negative Correlation ◽  
Cross Sectional Study ◽  
Variceal Hemorrhage ◽  
Sectional Study ◽  
Cross Sectional ◽  
Grade Ii ◽  
Cirrhotic Patients

Background: Bleeding from esophageal varices is a life-threatening complication in cirrhosis. Screening endoscopy is recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage, but this is an invasive procedure and has limitations. Therefore, thrombocytopenia has been proposed to predict the existence and grade of esophageal varices. The aim of the current study was to determine a correlation between platelet count and grades of esophageal varices in patients with liver cirrhosis. Methods: This cross-sectional study was conducted at the POF Hospital, Wah Cantt from 1st October, 2017 to 30th May, 2018. Newly diagnosed cases of cirrhosis having varices of any grade on endoscopy were included. Endoscopic findings of patients were standardized using Paquet grading system. On the basis of platelet count, patients were divided into four subgroups. Platelet count groups were correlated with grading of esophageal varices using Spearman rank correlations. Chi Square test was used to see association between the platelet count and grade of esophageal varices. Results: 110 patients were included in the study, 55.5% (n=61) were male. Mean age of the patients was 59.89±9.01 years. Platelet count was <50,000/uL in 35.5% patients, 50,000-99,000/uL in 26.4%, 100,000-150000 in 12.7%, and >150,000/uL in 25.5% patients. Grade I esophageal varices were found in 23.6% of patients, whereas grade II, III and IV were found in 24.5%, 33.6% and 18.2% of patients, respectively. Mean platelet count was 213884.62/mm3 in patients with grade I varices, whereas it was 119518.52/mm3, 58386.49/mm3 and 21600.00/mm3 in patients with grade II, III and IV varices, respectively (p=<0.0001). A significant negative correlation between platelet count and grades of esophageal varices was found (p<0.001). Conclusion: Platelet count can predict the grade of esophageal varices in cirrhotic patients. There is significant negative correlation between platelet count and grades of esophageal varices.

scholarly journals Association of Non HDL-Cholesterol and other lipid parameters in patients with Acute Coronary Syndrome.

2021 ◽  
Vol 29 (01) ◽  
pp. 82-87
Author(s):  
Syeda Sabahat Haider ◽  
Muhammad Shahid ◽  
Khalid Razaq ◽  
Shama Iqbal ◽  
Muhammad Tariq Ghafoor ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Total Cholesterol ◽  
Statistical Significance ◽  
Sampling Technique ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Control Group ◽  
P Value ◽  
Cross Sectional ◽  
Coronary Syndrome

Objective: To determine the frequency of hypercholesterolemia in patients who are diagnosed with acute coronary syndrome and to also document the association of Non HDL-C with Acute coronary syndrome in these patients. Study Design: Observational Cross Sectional study. Setting: Department of Cardiology and Pathology of Sheikh Zayed Hospital, Rahim Yar Khan. Period: September 2019 to February 2020. Material & Methods: One hundred and thirty five patients with Acute coronary syndrome were included using non probability purposive sampling technique and equal number of patient who visited the outpatient department or admitted in indoor with complaints other than ACS were taken as control (n=135). Frequency and percentages were calculated and odd ratio was determined to see the association. Statistical significance was set at P-value<0.05. Results: Patient’s mean age was 55.5±12.4 years and there were 98(73%) male and 37(27%) female. Higher Non HDL-C (>130mg/dl) was found in 120(88.9%) cases and in 38(28.1%) controls with odd ratio 20.4211 at 95 %CI and p value <0.001.Hypercholesterolemiawas seen in 49(36.3%) of the cases while in 21(15.6%) of control group (without ACS) with odd ratio of 3.3 and p-value <0.001. Odds ratio was maximum for Non HDL cholesterol, followed by LDL cholesterol, HDL cholesterol and Total cholesterol. Conclusion: Non-HDL cholesterol showed a good association in patients with ACS than with primary target LDL-C or total cholesterol.

scholarly journals ANALYSIS OF PLATELET COUNT ON FIBROSIS DEGREE IN CHRONIC HEPATITIS B PATIENTS

2018 ◽  
Vol 24 (2) ◽  
pp. 165
Author(s):  
Hairul Anwar ◽  
Mutmainnah Mutmainnah ◽  
Ibrahim Abdul Samad
Keyword(s):  
Chronic Hepatitis ◽  
Platelet Count ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Complete Blood Count ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
B Virus ◽  
Spearman Correlation Test

Chronic hepatitis B is an infectious liver disease caused by hepatitis B virus that persist for more than 6 months. Fibrosis is a result of fibrogenesis which is the formation of connective tissue (scarring) caused by liver tissue damage. Liver damage will affect the production of thrombopoetin causing disturbances in the balance between destruction and production of platelet resulting in decreased platelet counts. This study was a retrospective cross-sectional study by taking the data from medical records of chronic hepatitis B patients who were tested for complete blood count and fibroScan at the Dr.Wahidin Sudirohusodo Hospital Makassar from January 2014 to July 2016. The result showed a total of 323 chronic B hepatitis patients, 99 with severe fibrosis, 84 with moderate fibrosis and 140 with mild fibrosis. The Spearman correlation test showed a significant correlation between the platelet count and the degree of fibrosis (p <0.001) and showed a positive correlation between both of them with a very strong correlation (r = 0.802). The Kruskal-Wallis test showed a significant difference between platelet count and the degree of fibrosis (p<0.001). The conclusion is that a decreased platelet count is a sign of an increase in the degree of fibrosis in chronic hepatitis B patients. It is suggested to perform another study with larger samples based on the degree of fibrosis. 

scholarly journals Nurses Burnout, Resilience, and Its Association With Socio-Demographic Factors During COVID-19 Pandemic

2022 ◽  
Vol 12 ◽  
Author(s):  
Majid Heidari Jamebozorgi ◽  
Ali Karamoozian ◽  
Tayebe Ilaghinezhad Bardsiri ◽  
Hojjat Sheikhbardsiri
Keyword(s):  
Negative Correlation ◽  
Maslach Burnout Inventory ◽  
Significant Negative Correlation ◽  
Cross Sectional Study ◽  
Stressful Events ◽  
Personal Accomplishment ◽  
Cross Sectional ◽  
Work Related ◽  
Socio Demographic Factors

BackgroundIn the recent pandemic, nurses have faced workload and being exposed to burnout. Resilience helps address work-related psychological problems such as stressful events and burnout. According to the roles of nurses in the healthcare system, we investigated the relationship between resiliency and burnout in nurses.Material and MethodsIn this descriptive analytical cross-sectional study, 364 nurses participated from April to June 2021. Census sampling was used to recruit participants. Maslach burnout inventory (MBI), Connor-Davidson Resiliency Scale (CDRISC), and a demographic check-list were utilized to collect data. Data analysis was done using SPSS version 22. Shapiro-Wilk, Kruskal–Wallis test, Mann–Whitney U-test, correlation analysis, and generalized linear model were applied accordingly.ResultsOverall, the findings showed that nurses had severe symptoms of burnout and a moderate level of resilience. The two domains of burnout, emotional exhaustion and personal accomplishment had a significantly negative correlation with resilience (r = −0.442, p &lt; 0.001 and r = −0.351, p = 0.03, respectively). Linear regression showed that demographic characteristics (Hospital type, ward type, gender, and overtime) were the major predictors of the 3 sub-categories of burnout. A significant negative correlation was observed between burnout and resilience highlighting the role of resilience in reducing burnout (P &lt; 0.05).ConclusionIn order to help nurses to tackle and endure burnout in pandemic times, there is a need to implement national and local policies to help them accordingly.

scholarly journals Prevalence of Malnutrition Inflammation Complex Syndrome among Patients on Maintenance Haemodialysis at Muhimbili National Hospital in Tanzania: A Cross-Sectional Study

2020 ◽  
Author(s):  
Puneet Kishore Bramania ◽  
Paschal Ruggajo ◽  
Rimal Bramania ◽  
Muhiddin Mahmoud ◽  
Francis Fredrick Furia
Keyword(s):  
Total Cholesterol ◽  
Complete Blood Count ◽  
Early Recognition ◽  
Cross Sectional Study ◽  
Dar Es Salaam ◽  
Muhimbili National Hospital ◽  
National Hospital ◽  
Cross Sectional ◽  
Reverse Epidemiology ◽  
Maintenance Haemodialysis

Abstract Background: Malnutrition, inflammation, and the combination thereof are predictors of poor outcomes in haemodialysis patients. Malnutrition Inflammation Complex Syndrome (MICS) is an accelerator of atherosclerosis and portends high mortality. Early recognition and treatment of MICS may help to improve the clinical outlook of such patients. This study investigated the prevalence of MICS and its associated factors among patients on maintenance haemodialysis at Muhimbili National Hospital (MNH) in Dar es Salaam, Tanzania. Methods: This was a prospective cross-sectional observational study done among 160 adult patients on maintenance haemodialysis at MNH in 2019. All participants provided written informed consent. Questionnaires were used to collect data and patients’ blood was tested for complete blood count (CBC), C-reactive protein (CRP), ferritin, transferrin, creatinine, urea, total cholesterol, and albumin. The Malnutrition Inflammation Score was used to assess MICS and its severity. Data analysis was done using the SPSS 20 software. Results: Of the 160 patients included in the study, 111 (69.4%) were male. The mean age (±SD) of patients and mean duration (±SD) on haemodialysis were 52.2(13.3) years and 22(18) months respectively. MICS was prevalent in 46.3% (mild in 24.4% and moderate to severe in 21.9%). Long-term haemodialysis (>4years) was an independent predictor of MICS [Adjusted Odds Ratio, AOR 5.04 (95% CI: 1.33–19.2), p<0.05]. Hypercholesterolaemia was a negative predictor of MICS [AOR 0.11 (95% CI: 0.01-0.97), p<0.05]. Patients with MICS had significantly lower mean body mass index, serum albumin, total cholesterol, transferrin, haemoglobin, and creatinine levels. The presence of MICS was higher in underweight patients and those who had inflammation. Haemodialysis adequacy did not correlate with MICS. Conclusion: Malnutrition Inflammation Complex Syndrome is relatively common among patients on haemodialysis in Dar es Salaam, Tanzania. Our study has shown a longer duration on haemodialysis to be associated with the occurrence of MICS; on the contrary, having hypercholesterolaemia seems to be protective against MICS consistent with the concept of reverse epidemiology. Patients on haemodialysis should be assessed regularly for malnutrition and inflammation and should receive appropriate and timely treatment to reduce the burden of associated morbidity, and mortality to these patients.

scholarly journals Platelet Count/Spleen Diameter Ratio as a Predictor of Esophageal Varices in Patients with Liver Cirrhosis

2017 ◽  
Vol 15 (2) ◽  
pp. 37-40
Author(s):  
Dipendra Khadka ◽  
Sudhamshu KC ◽  
Sandip Khadka ◽  
Kiran Regmi ◽  
Pooja KC
Keyword(s):  
Liver Cirrhosis ◽  
Platelet Count ◽  
Esophageal Varices ◽  
Complete Blood Count ◽  
Liver Function Tests ◽  
Cross Sectional Study ◽  
Diameter Ratio ◽  
Cross Sectional ◽  
Predictive Values ◽  
Non Invasive

Introduction: Upper gastro-intestinal endoscopy still remains the gold standard for screening of patients suspected to have esophageal varices but not without limitations. So, this study was conducted to access the diagnostic validity and correlation between non-invasive parameters like platelet count, spleen diameter and their ratio with esophageal varices (EV) in patients with liver cirrhosis. Methods: A hospital based descriptive cross-sectional study was carried out in Liver unit of National Academy of Medical Sciences, Bir Hospital, from October 2016 to September 2017. Complete blood count, liver function tests, liver ultrasound and UGI endoscopy were done for all patients included in the study to detect esophageal varices and the platelet count/spleen diameter (PC/SD) ratio was calculated and analyzed to determine whether it can predict the presence of esophageal varices or not. Results: Total patients of liver cirrhosis studied after exclusion were 191 EV was present in 125 patients (65.4%). The platelet count/spleen diameter ratio using a cutoff value of ≤ 909 to detect EV independent of the grade had 93% sensitivity and 100% specificity and positive and negative predictive values of 100% and 91% respectively. Conclusions: PC/SD ratio now can be used as a predictor of presence of esophageal varices in liver cirrhosis.

scholarly journals Prevalence of malnutrition inflammation complex syndrome among patients on maintenance haemodialysis at Muhimbili National Hospital in Tanzania: a cross-sectional study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Puneet K. Bramania ◽  
Paschal Ruggajo ◽  
Rimal Bramania ◽  
Muhiddin Mahmoud ◽  
Francis F. Furia
Keyword(s):  
Total Cholesterol ◽  
Complete Blood Count ◽  
Early Recognition ◽  
Cross Sectional Study ◽  
Dar Es Salaam ◽  
Muhimbili National Hospital ◽  
National Hospital ◽  
Cross Sectional ◽  
Reverse Epidemiology ◽  
Maintenance Haemodialysis

Abstract Background Malnutrition, inflammation, and the combination thereof are predictors of poor outcomes in haemodialysis patients. Malnutrition Inflammation Complex Syndrome (MICS) is an accelerator of atherosclerosis and portends high mortality. Early recognition and treatment of MICS may help to improve the clinical outlook of such patients. This study investigated the prevalence of MICS and its associated factors among patients on maintenance haemodialysis at Muhimbili National Hospital (MNH) in Dar es Salaam, Tanzania. Methods This was a prospective cross-sectional observational study done among 160 adult patients on maintenance haemodialysis at MNH in 2019. All participants provided written informed consent. Questionnaires were used to collect data and patients’ blood was tested for complete blood count (CBC), C-reactive protein (CRP), ferritin, transferrin, creatinine, urea, total cholesterol, and albumin. The Malnutrition Inflammation Score was used to assess MICS and its severity. Data analysis was done using the SPSS 20 software. Results Of the 160 patients included in the study, 111 (69.4%) were male. The mean age (±SD) of patients and mean duration (±SD) on haemodialysis were 52.2(13.3) years and 22(18) months respectively. MICS was prevalent in 46.3% (mild in 24.4% and moderate to severe in 21.9%). Long-term haemodialysis (> 4 years) was an independent predictor of MICS [Adjusted Odds Ratio, AOR 5.04 (95% CI: 1.33–19.2), p < 0.05]. Hypercholesterolaemia was a negative predictor of MICS [AOR 0.11 (95% CI: 0.01–0.97), p < 0.05]. Patients with MICS had significantly lower mean body mass index, serum albumin, total cholesterol, transferrin, haemoglobin, and creatinine levels. The presence of MICS was higher in underweight patients and those who had inflammation. Haemodialysis adequacy did not correlate with MICS. Conclusion Malnutrition Inflammation Complex Syndrome is relatively common among patients on haemodialysis in Dar es Salaam, Tanzania. Our study has shown a longer duration on haemodialysis to be associated with the occurrence of MICS; on the contrary, having hypercholesterolaemia seems to be protective against MICS consistent with the concept of reverse epidemiology. Patients on haemodialysis should be assessed regularly for malnutrition and inflammation and should receive appropriate and timely treatment to reduce the burden of associated morbidity, and mortality to these patients.

scholarly journals Relationship between CBC and ESR and duration of disease in patients with systemic lupus erythematosus (SLE)

2018 ◽  
Vol 13 (2) ◽  
pp. 41-46
Author(s):  
Mahmuda Abira ◽  
Qazi Shamima Akhter
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Significant Negative Correlation ◽  
Control Group ◽  
Systemic Lupus ◽  
Initial Manifestation ◽  
Cross Sectional ◽  
Duration Of Disease

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease and is associated with considerable morbidity. Hematological abnormalities may be the initial manifestation. Duration may have impact on their hematological parameters. Objective: To observe the relationship of Complete Blood Count (CBC) and Erythrocyte sedimentation Rate(ESR) with duration of disease in patients with SLE. Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2016 to June 2017. Total 60 subjects including both sexes were selected with age ranging from 18 to 55 years. Among them, 30 subjects with SLE were study group and 30 age matched healthy subjects were control group. Total count of RBC, WBC, Platelet and ESR were estimated by automated hematology analyzer. Statistical analysis was done by unpaired Students æt” test, Chi Square test and Pearson’s correlation coefficient (r) test. Results: In this study, ESR was significantly (p<0.001) higher and RBC,WBC and platelet counts were significantly (p<0.001) lower in SLE patients in comparison to that of control. On correlation analysis, RBC and WBC showed significant negative correlation with duration of disease in patients with SLE. Conclusion: This study concludes that CBC and ESR were altered in SLE patients and it was related to duration of disease. J Bangladesh Soc Physiol. 2018, December; 13(2): 41-46

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