Correlation of Platelet Count and Hematocrit Levels to the Severity of Dengue Hemmoraghic Fever Patients at RSD dr. Soebandi Jember

Background: Bleeding from esophageal varices is a life-threatening complication in cirrhosis. Screening endoscopy is recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage, but this is an invasive procedure and has limitations. Therefore, thrombocytopenia has been proposed to predict the existence and grade of esophageal varices. The aim of the current study was to determine a correlation between platelet count and grades of esophageal varices in patients with liver cirrhosis. Methods: This cross-sectional study was conducted at the POF Hospital, Wah Cantt from 1st October, 2017 to 30th May, 2018. Newly diagnosed cases of cirrhosis having varices of any grade on endoscopy were included. Endoscopic findings of patients were standardized using Paquet grading system. On the basis of platelet count, patients were divided into four subgroups. Platelet count groups were correlated with grading of esophageal varices using Spearman rank correlations. Chi Square test was used to see association between the platelet count and grade of esophageal varices. Results: 110 patients were included in the study, 55.5% (n=61) were male. Mean age of the patients was 59.89±9.01 years. Platelet count was <50,000/uL in 35.5% patients, 50,000-99,000/uL in 26.4%, 100,000-150000 in 12.7%, and >150,000/uL in 25.5% patients. Grade I esophageal varices were found in 23.6% of patients, whereas grade II, III and IV were found in 24.5%, 33.6% and 18.2% of patients, respectively. Mean platelet count was 213884.62/mm3 in patients with grade I varices, whereas it was 119518.52/mm3, 58386.49/mm3 and 21600.00/mm3 in patients with grade II, III and IV varices, respectively (p=<0.0001). A significant negative correlation between platelet count and grades of esophageal varices was found (p<0.001). Conclusion: Platelet count can predict the grade of esophageal varices in cirrhotic patients. There is significant negative correlation between platelet count and grades of esophageal varices.

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Platelet count can predict the grade of esophageal varices in cirrhotic patients: a cross-sectional study

F1000Research ◽

10.12688/f1000research.28005.1 ◽

2021 ◽

Vol 10 ◽

pp. 101

Author(s):

Anum Afsar ◽

Muhammad Nadeem ◽

Syed Asim Ali Shah ◽

Huma Hussain ◽

Aysha Rani ◽

...

Keyword(s):

Platelet Count ◽

Negative Correlation ◽

Esophageal Varices ◽

Significant Negative Correlation ◽

Cross Sectional Study ◽

Variceal Hemorrhage ◽

Sectional Study ◽

Cross Sectional ◽

Grade Ii ◽

Cirrhotic Patients

Background: Bleeding from esophageal varices is a life-threatening complication in cirrhosis. Screening endoscopy is recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage, but this is an invasive procedure and has limitations. Therefore, thrombocytopenia has been proposed to predict the existence and grade of esophageal varices. The aim of the current study was to determine a correlation between platelet count and grades of esophageal varices in patients with liver cirrhosis. Methods: This cross-sectional study was conducted at the POF Hospital, Wah Cantt from 1st October, 2017 to 30th May, 2018. Newly diagnosed cases of cirrhosis having varices of any grade on endoscopy were included. Endoscopic findings of patients were standardized using Paquet grading system. On the basis of platelet count, patients were divided into four subgroups. Platelet count groups were correlated with grading of esophageal varices using Spearman rank correlations. Chi Square test was used to see association between the platelet count and grade of esophageal varices. Results: 110 patients were included in the study, 55.5% (n=61) were male. Mean age of the patients was 59.89±9.01 years. Platelet count was <50,000/uL in 35.5% patients, 50,000-99,000/uL in 26.4%, 100,000-150000 in 12.7%, and >150,000/uL in 25.5% patients. Grade I esophageal varices were found in 23.6% of patients, whereas grade II, III and IV were found in 24.5%, 33.6% and 18.2% of patients, respectively. Mean platelet count was 213884.62/mm3 in patients with grade I varices, whereas it was 119518.52/mm3, 58386.49/mm3 and 21600.00/mm3 in patients with grade II, III and IV varices, respectively (p=<0.0001). A significant negative correlation between platelet count and grades of esophageal varices was found (p<0.001). Conclusion: Platelet count can predict the grade of esophageal varices in cirrhotic patients. There is significant negative correlation between platelet count and grades of esophageal varices.

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Relationship between platelet indices and lipid status in chronic hookah consumption

Glasnik hemicara i tehnologa Bosne i Hercegovine ◽

10.35666/2232-7266.2021.56.05 ◽

2021 ◽

Keyword(s):

Platelet Count ◽

Total Cholesterol ◽

Negative Correlation ◽

Complete Blood Count ◽

Hdl Cholesterol ◽

Significant Negative Correlation ◽

Cross Sectional Study ◽

Control Group ◽

Cross Sectional ◽

Platelet Indices

Hookah smoking is a growing trend, both in the world and in Bosnia and Herzegovina. The aim of this study was to determine the value of platelet indices in hookah smokers and find out associations with lipid profile. Cross-sectional study included 60 students (30 chronic hookah smokers and 30 non-smokers). The complete blood count (erythrocytes, leukocytes, platelets, hemoglobin, hematocrit, erythrocyte and platelet indices), lipid parameters (total cholesterol, triglycerides, LDL-C, HDL-C) were determined. The platelet count, mean platelet volume and MPV/Platelets ratio were statistically significantly higher in chronic hookah consumers in the student population than in the control group (p <0.001). In addition, platelet count was in significant positive correlation with values of total cholesterol, LDL-C and negative correlation with value of HDL-C, while there was a significant negative correlation between mean platelets volume, and MPV/Platelets ratio with HDL cholesterol levels in chronic hookah smokers (p <0.05). These findings suggest that chronic hookah consumption could be associated with the development of atherosclerotic changes in blood vessels, which could lead to the development of long-term consequences on the cardiovascular system's function.

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Nurses Burnout, Resilience, and Its Association With Socio-Demographic Factors During COVID-19 Pandemic

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.803506 ◽

2022 ◽

Vol 12 ◽

Author(s):

Majid Heidari Jamebozorgi ◽

Ali Karamoozian ◽

Tayebe Ilaghinezhad Bardsiri ◽

Hojjat Sheikhbardsiri

Keyword(s):

Negative Correlation ◽

Maslach Burnout Inventory ◽

Significant Negative Correlation ◽

Cross Sectional Study ◽

Stressful Events ◽

Personal Accomplishment ◽

Cross Sectional ◽

Work Related ◽

Socio Demographic Factors

BackgroundIn the recent pandemic, nurses have faced workload and being exposed to burnout. Resilience helps address work-related psychological problems such as stressful events and burnout. According to the roles of nurses in the healthcare system, we investigated the relationship between resiliency and burnout in nurses.Material and MethodsIn this descriptive analytical cross-sectional study, 364 nurses participated from April to June 2021. Census sampling was used to recruit participants. Maslach burnout inventory (MBI), Connor-Davidson Resiliency Scale (CDRISC), and a demographic check-list were utilized to collect data. Data analysis was done using SPSS version 22. Shapiro-Wilk, Kruskal–Wallis test, Mann–Whitney U-test, correlation analysis, and generalized linear model were applied accordingly.ResultsOverall, the findings showed that nurses had severe symptoms of burnout and a moderate level of resilience. The two domains of burnout, emotional exhaustion and personal accomplishment had a significantly negative correlation with resilience (r = −0.442, p < 0.001 and r = −0.351, p = 0.03, respectively). Linear regression showed that demographic characteristics (Hospital type, ward type, gender, and overtime) were the major predictors of the 3 sub-categories of burnout. A significant negative correlation was observed between burnout and resilience highlighting the role of resilience in reducing burnout (P < 0.05).ConclusionIn order to help nurses to tackle and endure burnout in pandemic times, there is a need to implement national and local policies to help them accordingly.

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Assessment of the differentiated aspiration process of palivizumab

Acta Paulista de Enfermagem ◽

10.1590/1982-0194201400014 ◽

2014 ◽

Vol 27 (1) ◽

pp. 69-75

Author(s):

Rosemeire Sartori de Albuquerque ◽

Corintio Mariani Neto ◽

Gisleine Aparecida de Castro Arone ◽

Ana Aparecida Sanches Bersusa ◽

Vanessa Peres Leandro

Keyword(s):

Medical Records ◽

Care Management ◽

Planning Process ◽

Secondary Data ◽

Cross Sectional Study ◽

Team Work ◽

Public Expenditures ◽

Sectional Study ◽

Cross Sectional ◽

Management Planning

OBJECTIVE: Assess the differentiated aspiration process of palivizumab, from planning to administration, and from the patient's profile to obtained savings as a result of the optimization of doses.METHODS: Cross-sectional study carried out by means of secondary data obtained from the medical records of 858 children. Variables of the study were as follows: information on the profile of cared children, amount of acquired and administered doses, vaccination procedure, and optimized doses. Data were extracted from care management reports.RESULTS: The innovative technique and the vaccination planning allowed for 98 children to be favored by leftovers of the medication, implying savings of R$ 1.144.347,52 in 2012 and 2013.CONCLUSION: The employment of the differentiated aspiration process favored the availability of the medication to 54 children other than those previously programmed, and the application of 78 leftovers. The establishment of a previous management planning process of programmed contents to be administered to children, in compliance with their profile, especially their body weight, favored the inclusion of other admitted newborns. The systematization process of the team work toward the administration of palivizumab implied the reduction of public expenditures.

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Visfatin and Adiponectin Have an Opposite Correlation with Inflammation and Metabolic Syndrome in Non-Diabetic Obese Indonesian Men

The Indonesian Biomedical Journal ◽

10.18585/inabj.v1i3.104 ◽

2009 ◽

Vol 1 (3) ◽

pp. 81

Author(s):

Anna Meiliana ◽

Gatot Susilo Lawrence ◽

Ilhamjaya Patellongi ◽

Andi Wijaya ◽

Suryani As'ad

Keyword(s):

Metabolic Syndrome ◽

Negative Correlation ◽

Significant Negative Correlation ◽

Cross Sectional Study ◽

Cross Sectional ◽

Metabolic Complications ◽

The Metabolic Syndrome ◽

Parallel Increase ◽

Tnf Α ◽

Anti Inflammatory

BACKGROUND: Along with the increase in obesity is a parallel increase in the prevalence of metabolic complications of obesity, often referred to as the metabolic syndrome (MetS). The role of adipose tissue in MetS has continued to evolve with the description of numerous secretory peptides from adipocytes named adipocytokines or adipokines. Recent studies have found visfatin as the regulation of inflammatory and immunomodulating prosesses, meanwhile adiponectin was known to have a potent anti-inflammatory properties. Here we try to assess the correlation between those two adipokines to MetS, via an inflammatory pathway.METHODS: This was a cross-sectional study on 128 non diabetic obese male subject (waist circumferences ≥90 cm). Visfatin and adiponectin were assessed by ELISA. Statistical analysis was performed using SPSS for Windows v.16.00 with signifcantly p<0.05. The correlations among biomarkers were assessed using Spearman's Rho test.RESULTS: This study showed a significant positive correlation between levels of visfatin and inflammatory markers TNF-α (r=0.22, p<0.005), and hsCRP (r=0.12, p=0.19), significant negative correlation between levels of adiponectin and TNF-α (r=-0.22-8, p<0.005-1), adiponectin and hsCRP (r=-0.14, p=0.11) and visfatin (r=-0.029, p<0.01). Plasma visfatin levels were increased along with the number MetS components, white plasma adiponectin showed inversely relation.CONCLUSION: Our present study has shown that visfatin has a proinflammatory properties and adiponectin has an anti-inflammatory properties, and how they have an opposite effects on MetS. Visfatin was found to have a positive correlaton while adiponectin was found to have a negative correlation with the number of MetS components.KEYWORDS: Obesity, Inflammation, Metabolic Syndrome, Adipocytokines, Visfatin, Adiponectin, TNF-α, hsCRP

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Factors Associated with Types and Intensity of Postoperative Pain following Gynecological Laparoscopic Surgery: A Cross-Sectional Study

BioMed Research International ◽

10.1155/2017/2470397 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Chia-Fen Hsien ◽

Chiu-Lin Wang ◽

Cheng-Yu Long ◽

Yung-Hung Chen ◽

Winter Yu-Ning Lee ◽

...

Keyword(s):

Laparoscopic Surgery ◽

Postoperative Pain ◽

Negative Correlation ◽

Significant Negative Correlation ◽

Cross Sectional Study ◽

Surgical Wound ◽

Cross Sectional ◽

Vas Score ◽

Wound Pain ◽

Striae Gravidarum

Objective. To evaluate influences of various factors on the types and intensity of postoperative pain following gynecologic laparoscopic surgery. Study Design. Cross-sectional questionnaire and chart review. Results. A total of 84 questionnaires were distributed and returned. The types of postlaparoscopic pain are different in multiparous women and nulliparous ones (71.43% surgical wound pain versus 63.64% nonsurgical wound pain, p=0.0033) and those with striae gravidarum and without striae gravidarum (93.94% surgical wound pain versus 52.94% nonsurgical wound pain, p<0.0001). On postoperative day 1, the average VAS score is higher in nonsurgical wound pain than in surgical wound pain (5.62 ± 1.50 versus 3.51 ± 1.68, p<0.0001). The CO2 removal procedure has a significant negative correlation with the VAS of nonsurgical wound pain (coefficient: -0.4339, p=0.0187). Conclusion. Our study suggests that women with abdominal rigidity (nulliparous, no striae gravidarum) experience mainly nonsurgical wound pain, while women with abdominal wall laxity mostly experience surgical wound pain. The VAS score of nonsurgical wound pain is greater than surgical wound pain on postoperative day 1. The CO2 removal procedure has negative correlation to the VAS score of nonsurgical wound pain on postoperative day 1.

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Prevalence of Potential Drug–Drug Interaction Risk among Chronic Kidney Disease Patients in a Spanish Hospital

Pharmaceutics ◽

10.3390/pharmaceutics12080713 ◽

2020 ◽

Vol 12 (8) ◽

pp. 713

Author(s):

Gracia Santos-Díaz ◽

Ana María Pérez-Pico ◽

Miguel Ángel Suárez-Santisteban ◽

Vanesa García-Bernalt ◽

Raquel Mayordomo ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Drug Interactions ◽

Cross Sectional Study ◽

Potential Drug ◽

Cross Sectional ◽

Major Health Problem ◽

Major Health ◽

Spanish Hospital

Chronic kidney disease (CKD) is a major health problem worldwide and, in Spain, it is present in 15.1% of individuals. CKD is frequently associated with some comorbidities and patients need to be prescribed multiple medications. Polypharmacy increases the risk of adverse drug reactions (ADRs). There are no published studies evaluating the prevalence of potential drug–drug interactions (pDDIs) among CKD patients in any European country. This study was aimed to determine the prevalence, pattern, and factors associated with pDDIs among CKD patients using a drug interactions program. An observational cross-sectional study was carried out at Plasencia Hospital, located in Spain. Data were collected among patients with CKD diagnoses and pDDIs were assessed by the Lexicomp® Drug Interactions platform. Data were obtained from 112 CKD patients. A total number of 957 prescribed medications were acknowledged, and 928 pDDIs were identified in 91% of patients. Age and concomitant drugs were significantly associated with the number of pDDIs (p < 0.05). According to the results, the use of programs for the determination of pDDIs (such as Lexicomp®) is recommended in the clinical practice of CKD patients in order to avoid serious adverse effects, as is paying attention to contraindicated drug combinations.

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Prevalence and Associated Factors of Malnutrition in Patients with Intracranial Infections at Sanglah Hospital Denpasar

GSC Advanced Research and Reviews ◽

10.30574/gscarr.2021.9.1.0228 ◽

2021 ◽

Vol 9 (1) ◽

pp. 044-050

Author(s):

Ayu Diah Perdana Paramita ◽

I Gusti Ngurah Made Suwarba ◽

Dewi Sutriani Mahalini ◽

I Gusti Lanang Sidiartha

Keyword(s):

Pediatric Patients ◽

Secondary Data ◽

Final Diagnosis ◽

Acute Malnutrition ◽

Cross Sectional ◽

Major Health Problem ◽

Major Health ◽

Intracranial Infection ◽

Affect Body Weight ◽

Intracranial Infections

Malnutrition is a major health problem in developing countries, it can occur acutely, chronically or combination of both. Malnutrition aggravates the condition of infectious diseases, including intracranial infections. Hereby we aimed to determine the prevalence and factors associated with malnutrition in pediatric patients with intracranial infections in Sanglah Central General Hospital. This cross-sectional analytic study was conducted in patients with final diagnosis intracranial infection whom were treated from January 2019 to March 2021. The study was conducted in pediatric patients aged 1 month-18 years old and patient would be excluded if had any of these conditions: 1) incomplete medical records, 2) discharge by his/her own request, 3) hydrocephalus for which VP shunt had not been performed, 4) diagnosis of tumor or mass that could affect body weight measurement. Secondary data such as weight/height for children <5 years and BMI/age for children >5 years were measured in growth curve by using the WHO Anthro application. Total samples were 83 children with predominance age group was 0-5 years old. Malnutrition was found in 48.1% patients. Chronic malnutrition was more common than acute malnutrition (32.5% vs. 31.3%). Age below 5 years has relationship with the incidence of acute malnutrition in pediatric patients with intracranial infection (p: 0.008, 95% CI: 0.076-0.675). The incidence of malnutrition in children with intracranial infections in Sanglah Hospital during January 2019 to March 2021 was 48.1%, and age < 5 years had significant relation to the incidence of malnutrition in children with intracranial infections.

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Determination of antibiotic resistance of Salmonella isolated from pork, beef, and chicken meat at the retail markets in Hanoi

Vietnam Journal of Biotechnology ◽

10.15625/1811-4989/16/3/13476 ◽

2018 ◽

Vol 16 (3) ◽

pp. 553-564

Author(s):

Nguyen Thanh Viet ◽

Nghiem Ngoc Minh ◽

Vo Thi Bich Thuy

Keyword(s):

Growth Promotion ◽

Multidrug Resistant ◽

Cross Sectional Study ◽

Cross Sectional ◽

Major Health Problem ◽

Major Health ◽

Retail Meats ◽

Control Programmes ◽

And Control

Salmonella resistance to antimicrobials is a major health problem in the world. Thus, we conducted a cross-sectional study to determine the prevalence of Salmonella serovars isolates from retail meats in Ha Noi and their susceptibility to 8 antimicrobials commonly used in the treatment and growth promotion in domestic livestocks in Vietnam. Salmonella was detected in 25/90 (27.8%) samples. Nine different serovars were identified, including S. Typhimurium (44%), S. Derby (16%), S. Warragul, S. Indiana, S. Rissen (8%), and S. London, Meleagridis, Give, Assine (4%). S. Typhimurium (44 %) is the most prevalent types. Resistance to at least one antibiotic was showed in 13 strains (52%). All isolates were 44% (11/25) resistant to streptomycin and tetracycline, 32% (8/25) resistant to chloramphenicol. The multiple antimicrobial resistance accounted for 69.2% of isolates (9/13). All strains were susceptible to ceftazidime. This data indicated that the retail meats could constitute a source of human exposure to multidrug-resistant Salmonella and therefore could be considered a potential vehicle of resistant Salmonella foodborne diseases. There is an urgent need for surveillance and control programmes on Salmonella and use of antimicrobials in Vietnam to protect the health of consumers.

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