scholarly journals Phytochemical Screening and Determination of Antibacterial, Anti-Tumorigenic and DNA Protection Ability of Root Extracts of Saussurea Lappa

2017 ◽  
Vol 4 (4) ◽  
Keyword(s):  
Phytochemical Screening ◽  
Dna Protection ◽  
Root Extracts ◽  
Saussurea Lappa

scholarly journals KARAKTERISTIK DAN SKRINING FITOKIMIA EKSTRAK ETANOL 70% BATANG KEPUH (Sterculia foetida L.)

Jurnal Kimia ◽  
2019 ◽  
Vol 13 (1) ◽  
pp. 22
Author(s):  
N. P. S. E. Cahyani ◽  
J. Susiarni ◽  
K. C.S. Dewi ◽  
N. L.P. Melyandari ◽  
K. W.A. Putra ◽  
...  
Keyword(s):  
Moisture Content ◽  
Water Content ◽  
Ethanol Extract ◽  
Phytochemical Screening ◽  
Residual Solvent ◽  
Solvent Content ◽  
Residual Content ◽  
Ethanol Level ◽  
Anti Inflammatory

Kepuh (Sterculia foetida L) is a type of kapok plant that has been scientifically proven to have activity as an anti-inflammatory and analgesic. 70% ethanol extract of stem stem is obtained by maceration using 70% ethanol. Examination of the characteristics of 70% ethanol extract of kepuh stem included organoleptic, of moisture content and determination of residual solvent content. Phytochemical screening of 70% ethanol extract of kepuh bark includes: alkaloid, flavonoid, saponin, tannin , polyphenol, and examination of glycosides. The results of the examination of the characteristics of 70% ethanol extract of kepuh stem obtained water content of 8.66 ± 0.748%, the residual content of the solvent had a 0 (zero) ethanol level. The results of phytochemical screening showed 70% ethanol extract of stem stem containing steroid compounds, triterpenoids, flavonoids, saponins, tannins and polyphenols. The identification using UV-Vis spectrophotometry produced ? 212, the absorbance was 1.8601 and ? 284, the absorbance was 0.42186.

scholarly journals Phytochemical screening and in vitro antibacterial, antifungal, antioxidant and antitumor activities of the red propolis Alagoas

2019 ◽  
Vol 79 (3) ◽  
pp. 452-459 ◽  
Author(s):  
F. R. G. Silva ◽  
T. M. S. Matias ◽  
L. I. O. Souza ◽  
T. J. Matos-Rocha ◽  
S. A. Fonseca ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Gallic Acid ◽  
Bioactive Metabolites ◽  
Diffusion Method ◽  
Total Phenolic ◽  
Phytochemical Screening ◽  
Dpph Method

Abstract The study aimed to evaluate the antimicrobial activity, antioxidant, toxicity and phytochemical screening of the Red Propolis Alagoas. Antimicrobial activity was evaluated by disk diffusion method. Determination of antioxidant activity was performed using the DPPH assay (1.1-diphenyl-2-picrylhydrazyl), FTC (ferric thiocyanate) and determination of phenolic compounds by Follin method. Toxicity was performed by the method of Artemia salina and cytotoxicity by MTT method. The phytochemical screening for the detection of allelochemicals was performed. The ethanol extract of propolis of Alagoas showed significant results for antimicrobial activity, and inhibitory activity for Staphylococcus aureus and Candida krusei. The antioxidant activity of the FTC method was 80% to 108.3% hydrogen peroxide kidnapping, the DPPH method showed an EC50 3.97 mg/mL, the content of total phenolic compounds was determined by calibration curve gallic acid, resulting from 0.0005 mg/100 g of gallic acid equivalent. The extract was non-toxic by A. salina method. The propolis extract showed high activity with a higher percentage than 75% inhibition of tumor cells OVCAR-8, SF-295 and HCT116. Chemical constituents were observed as flavonones, xanthones, flavonols, and Chalcones Auronas, Catechins and leucoanthocyanidins. It is concluded that the extract can be tested is considered a potential source of bioactive metabolites.

scholarly journals Acute Toxicity, Phytochemical Screening, Analgesic, and Anti-Inflammatory Activities of Aqueous and Methanol Root Extracts of Maerua triphylla A. Rich. (Capparaceae)

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Brian Muyukani Wangusi ◽  
Laetitia Wakonyu Kanja ◽  
Isaac Mpapuluu Ole-Mapenay ◽  
Jared Misonge Onyancha
Keyword(s):  
Acetic Acid ◽  
Diclofenac Sodium ◽  
Root Extract ◽  
Phytochemical Screening ◽  
Paw Edema ◽  
Reference Drug ◽  
Root Extracts ◽  
Significant Difference ◽  
Anti Inflammatory ◽  
Aqueous Root Extract

Maerua triphylla root extracts are used by Maasai and Kikuyu communities in Kenya to manage headaches, stomachaches, migraines, and rheumatism. However, scientific data on their safety and efficacy are limited. The current study aims to investigate the safety, phytochemical constituents, analgesic, and anti-inflammatory activities of M. triphylla root extracts. Aqueous and methanol M. triphylla root extracts were prepared by cold maceration, and the extracts’ safety was evaluated using Wistar rats according to the Organization for Economic Cooperation and Development (2008) guidelines. Standard qualitative phytochemical screening methods were used for the detection of various phytochemical groups in the extracts. Analgesic activity assay in Swiss albino mice was done using the acetic acid-induced writhing test, while anti-inflammatory activity was determined in Wistar rats using the acetic acid-induced paw edema method. The methanol and aqueous extracts revealed LD50 > 2000 mg/kg bw, classifying them as nontoxic. The presence of cardiac glycosides, flavonoids, alkaloids, and phenols was observed in both extracts. However, saponins were only present in the methanol extract. In the analgesic study, mice that received 100 mg/kg bw and 500 mg/kg bw of aqueous root extract of M. triphylla had significantly lower acetic acid-induced writhing than mice that received acetylsalicylic acid 75 mg (reference drug) ( p < 0.05 ). Additionally, mice that received 500 mg/kg bw of methanol root extract of M. triphylla had significantly lower acetic acid-induced writhing than mice that received the acetylsalicylic acid 75 mg ( p < 0.05 ). In the anti-inflammatory study, there was no significant difference ( p < 0.05 ) between the inhibitory activity of different doses of the aqueous root extract of M. triphylla and a 50 mg/kg dose of diclofenac sodium (reference drug) on acetic acid-induced paw edema in rats. Moreover, there was no significant difference in the inhibitory activity of 100 mg/kg bw and 500 mg/kg bw doses of the methanol root extract of M. triphylla and a 50 mg/kg dose of diclofenac sodium on acetic acid-induced paw edema ( p > 0.05 ). These findings suggest that the roots of M. triphylla may be useful in the safe mitigation of pain and inflammation and therefore support their ethnomedicinal use in the management of pain and inflammation.

Microscopic features and phytochemistry of two Congolese medicinal plants: Aframomum alboviolaceum (Ridley) K. Schum, and Aframomum angustifolium (Sonn.) K. Schum. (Zingiberaceae).

2021 ◽  
Vol 1 (2) ◽  
pp. 043-052
Author(s):  
Clément Liyongo Inkoto ◽  
Koto-Te-Nyiwa Ngbolua ◽  
Adrien Tuwisana Masunda ◽  
Carlos Nkongolo Kabengele ◽  
Jeff Bekomo Iteku ◽  
...  
Keyword(s):  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Traditional Healers ◽  
Phytochemical Screening ◽  
Calcium Oxalate Crystals ◽  
Total Polyphenols ◽  
Microscopic Features ◽  
Chemical Groups ◽  
First Time

The leaves and seeds of Aframomum alboviolaceum and Aframomum angustifolium are specifically used by traditional healers in the Democratic Republic of Congo (DRC) for the treatment of several pathologies. The aim of present study was to determine the microscopic characteristics and phytochemical composition of these species of the genus Aframomum. The microscopic study of these plants revealed the presence of punctate vessels, fiber cluster with calcium oxalate crystals, isolated unicellular hair, fibers, starch grains, spiral vessel fragments, fiber fragments, and indistinct parenchyma fragments. Phytochemical screening revealed several chemical groups such as phenolic acids, flavonoids, coumarins, alkaloids, terpenes, iridoids, saponins etc. The determination of total polyphenols, flavonoids and tannins gave contents ranging from 14.95 ± 0.45 and 63.98 ± 2.04 mgGAE/g, 0.16 ± 0.01 and 10.68 ± 0.32 mgQE/g and between 1.28 ± 0.03 and 28.51 ± 0.56 mg CAE/g respectively. In general, the leaves are richer in secondary metabolites, polyphenols, flavonoids and tannin than the seeds. Both plants also contain iron, magnesium, calcium and sodium. To our knowledge, this is the first time that histological elements have been identified in the leaves and seeds of A. angustifolium.

Phytochemical screening and determination of phenolics and flavonoids in Dillenia pentagyna using UV–vis and FTIR spectroscopy

2020 ◽  
Vol 242 ◽  
pp. 118717 ◽  
Author(s):  
Tarun Kumar Patle ◽  
Kamlesh Shrivas ◽  
Ramsingh Kurrey ◽  
Seema Upadhyay ◽  
Rajendra Jangde ◽  
...  
Keyword(s):  
Ftir Spectroscopy ◽  
Phytochemical Screening

Determination of Shatavarin IV in Root Extracts ofAsparagus racemosusby HPLC-UV

2012 ◽  
Vol 2 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Ghasem Haghi ◽  
Alireza Hatami ◽  
Mehdi Mehran
Keyword(s):  
Root Extracts

Phytochemical Screening, Antimicrobial Activities and Nutritional content of Jatropha Tanjorensis Leaves

2019 ◽  
Vol 1 ◽  
pp. 108-113
Author(s):  
B A Anhwange ◽  
I G Agbidye ◽  
B A Kyenge ◽  
P O Ngbede
Keyword(s):  
Proximate Composition ◽  
Antimicrobial Agents ◽  
Reducing Sugars ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Phytochemical Screening ◽  
Bioactive Components ◽  
Standard Procedures ◽  
Hexane Extracts

The leaves of Jatropha tanjarensis were collected and assessed for their phytochemical compositions and antimicrobial activities using methanolic and hexane extracts as to determine the bioactive components and their effects on microorganisms. Also, the nutritional potential was investigated through the determination of proximate composition using standard procedures. The result of phytochemical screening indicated the presence of saponins, cardiac glycosides, reducing sugars, steroids, alkaloids and flavonoids in methanolic extract, the same observation was recorded in n-hexane extract except that reducing sugars were absent and phlobotannins were present. The antimicrobial activities of the leaves extract show that it have some antimicrobial properties. Results of the proximate composition and mineral analysis revealed that the plant is a good source of fiber and minerals. Therefore, leaves of Jatropha tanjarensisapart from being used as antimicrobial agents, can serve as good sources of fiber and minerals when used as vegetables.

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