scholarly journals PENGARUH LATIHAN FISIK AEROBIK TERHADAP KOLESTEROL HIGH DENSITY LIPOPROTEIN (HDL) PRIA DENGAN BERAT BADAN LEBIH (OVERWEIGHT)

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Gloria Hengkengbala ◽  
H. Polii ◽  
H. I. S. Wungouw

Abstract: Several studies have suggested that aerobic exercise can affect the metabolism of cholesterol in the blood, one of which cholesterol High Density Lipoprotein (HDL), otherwise known as “good cholesterol”, but it has not been mentioned in detail what kind of exercise and how much exercise intensity long and also how many levels of HDL can be improved with practice. Aerobic physical exercise using a stasionary bicycle made for one’s physicalfitness test. This study aimed to determine the effect of aerobic exercise on HDL overweight male student of the Unsrat Medical Faculty. This research is analytic experimental design field with one group pre-post test. The study subject were 28 students medical Unsrat 2009 (18-25 years) with IMT > 23 who fulfil the inclusion criteria. Subjects were given aerobic physical exercise in the fitness center Manado for 3 weeks with a frequency of three times a week, with duration of 30 minutes of exercise, then it is conducted normality test of data distribution, and data analysis followed by paired t test for normally distributed data obtained. The result showed an increase in the mean  levels of HDL subjects 44.85±7.98 mg/dL to 46.89±8.96 mg/dL (p=0.104) but trough paired t test, Ido not get meaningful results after doing aerobic exercise (p>0.005). Aerobic Phycical Exercise on a regular basis using a stationary bike on the overweight men student can increase the mean HDL cholesterol levels but no significant difference from the mean value.Keywords: Aerobic Physical Exercise, HDL, Overweight.  Abstrak: Beberapa penelitian telah menyebutkan bahwa latihan fisik aerobik dapat mempengaruhi metabolisme kolesterol dalam darah salah satunya kolesterol HDL (High Density Lipoprotein) atau dikenal sebagai “kolesterol baik”, namun belum disebutkan secara terperinci jenis latihan fisik seperti apa dan dengan intensitas latihan berapa lama dan juga berapa banyak kadar HDL yang dapat ditingkatkan dengan latihan. Latihan fisik aerobik dengan menggunakan sepeda statis yang dilakukan untuk tes kebugaran fisik seseorang. Penelitian ini bertujuan untuk mengetahui pengaruh latihan fisik aerobic terhadap kadar HDL mahasiswa pria Fakultas Kedokteran Unsrat dengan berat badan lebih.  Jenis penelitian ini bersifat eksperimental lapangan dengan rancangan pre-post one group test. Subjek  penelitian sebanyak 28 mahasiswa Kedokteran UNSRAT Angkatan 2009  (18-25 tahun) dengan IMT ≥ 23 yang memenuhi kriteria inklusi. Subyek  diberikan latihan fisik aerobic di pusat Kebugaran Manado selama 3 minggu dengan frekuensi 3 kali seminggu, dengan lamanya latihan 30 menit, selanjutnya dilakukan uji normalitas distribusi data, kemudian dilanjutkan analisis data dengan uji t berpasangan karena data yang didapat berdistribusi normal. Hasil penelitian didapatkan terjadi peningkatan nilai rerata kadar HDL subyek  44,85 ± 7.98 mg/dL menjadi 46.89 ±8.96 mg/dL (p= 0.104) namun  melalui uji t berpasangan mendapatkan hasil yang tidak bermakna sesudah melakukan latihan fisik aerobik (p >0.005). Simpulan: Latihan fisik aerobik menggunakan sepeda statis secara teratur pada mahasiswa pria dengan berat badan lebih dapat meningkatkan nilai rerata kadar HDL tetapi tidak terdapat perbedaan yang bermakna dari nilai rerata tersebut.Kata Kunci: latihan Fisik Aerobik, HDL, overweight.

2021 ◽  
Vol 9 (4) ◽  
pp. 65-68
Author(s):  
Noor Muhammad Marwat ◽  
Shah Khalid ◽  
Pir Muhammad Abdul Aziz Shah ◽  
Fayaz ul Hasnain ◽  
Rashid Naeem Khan

Purpose: The purpose of this study to find out the impacts of a 6-weeks supervised aerobic exercise protocol on High-Density Lipoprotein among adults aged between 25-35 years was evaluated. Methodology: Researchers through a non-probability sampling procedure selected thirty (30) volunteers ranging from 25-35 untrained adults from Lakki Marwat. Researchers used a six-week aerobic exercise protocol to collect relevant information from the targeted dependent variables. The CHOD PAP method was used to measure the High-Density Lipoprotein (HDL) of adults. All the data collected from pre-and post- (HDL) tests were recorded in numerical form and analyzed by using a t-test. Main Findings: The results of the study indicate that the six-week aerobic exercise protocol program had no significant difference on pre-and post-intervention quantities of HDL of Experimental Group which is (P>0.05). The implication of the Study: The aerobic exercise programs used for this particular study may help adults to improve and maintain their health status, proper social stature, and lipid profile. An increase in the HLD is ideal as this increase in the HDL helps to prevent cardiovascular diseases particularly the heart valves from stroke and cardiac arrest and academic achievements of the participants. Novelty: So far, no particular research has been conducted on the social implications of exercise effects on adults. Future researchers may work on the social habits of physically fit adults and their input to society.


Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Rafeal L Baker ◽  
Jean N Utumatwishima ◽  
Stephanie T Chung ◽  
Anne E Sumner

Introduction: For Africans living in the United States, the extent to which stress-induced physiologic dysfunction varies by reason for immigration is unknown. Allostatic load score (ALS) is used to assess physiologic stress. ALS has biomarkers in 3 domains: cardiovascular, metabolic and immune. However, there are many ALS equations and the number of biomarkers in each domain varies. In the cardiac domain of ALS, equations use either triglyceride (TG) or high density lipoprotein (HDL). A specific problem for African descent populations is that HDL may be superior to TG as a marker of insulin resistance and cardiac risk. Objective: Our primary goal in 95 African immigrants (71% male, age 42±10, (mean±SD), range 22-62y) was to determine if ALS varied by reason for immigration. Our secondary goal was to evaluate 4 different ALS equations to determine if there was a difference in ALS performance depending on whether HDL or TG was the included biomarker. Methods and Results: For all 4 equations, the reasons for immigration from lowest to highest ALS were: family reunification, lottery for self and immediate family, marriage, asylum, work and study (Figure 1). As the first 3 reasons for immigration promoted family unity, they were grouped together (Group 1). The Africans who came for other reasons were grouped together (Group 2). Equations 1 and 2 included HDL as a biomarker. For these equations, ALS in Group 1 vs. Group 2 were: 1.7±1.3 vs. 2.8±1.7, P <0.01 and 1.4±1.2 vs. 2.3±1.7, P <0.01 resp. Equations 3 and 4 used TG. For these two equations ALS in Group 1 vs. Group 2 were: 2.2±1.6 vs. 2.9±2.0, P =0.08 and 2.1±1.4 vs. 2.9±2.0, P =0.03 resp. In Equations 1 and 2, when HDL was replaced by TG, the significant difference in ALS between groups declined. In Equations 3 and 4, when TG was replaced by HDL, the significant difference in ALS between groups increased. Conclusions: ALS varies by reason for immigration and is easier to detect in ALS equations which use HDL rather than TG.


2018 ◽  
Vol 51 (4) ◽  
pp. 173
Author(s):  
Vita Previa Indirayana ◽  
Gita Gayatri ◽  
N. R. Yuliawati Zenab

Background: Model analysis constitutes an essential aspect of orthodontic diagnostic practice. Pavan has developed an application to simplify the mathematical calculations employed in orthodontic model analysis. Purpose: This study was conducted to obtain the differences in results and time periods of model analysis using conventional means and iModelAnalysis. Methods: The research represented a comparative analytic study. The populations comprised dental casts dating from 2014 in the Orthodontics Laboratory of Padjadjaran University. The samples comprised 31 dental casts which were subjected to a total sampling method consisting of two treatments; a conventional method calculation and one using iModelAnalysis. A normality test was conducted and processed using a paired t-test with α=0.05. Results: The means of arch length discrepancies were 1.64±2.63 mm and 1.37±3.07 mm for the conventional methods and 1.65±2.43mm and 1.42±3.04mm for iModelAnalysis. The results of a Bolton analysis for conventional methods were 78.05±2.69% and 91.93±1.29%, while those for iModelAnalysis were 77.91±2.70% and 91.96±2.13%. A Howes analysis of conventional methods produced a result of 45.56±2.83%, while for an iModelAnalysis one of 45.56±2.85%. Pont analysis for conventional methods was 39.35±0.04 mm and 49.17±2.55 mm, while for iModelAnalysis it was 39.35±0.07 mm and 49.19±2.57mm. The mean of the duration of analysis using conventional methods was 1703.81±56.46 seconds, while for iModelAnalysis it was 990.06±34.87 seconds. A normality test confirmed that the data was normally distributed (p>0.05). The results of a paired sample t-test with p>0.05 showed that there was no significant difference between the results of each analysis, while there was significant difference in the time period of analysis. Conclusion: There was no difference in the analysis results. However, there was difference in the time period of analysis between conventional methods and that of iModelAnalysis.


Author(s):  
Intje S Dahlan ◽  
Mardiah Tahir ◽  
Efendi Lukas ◽  
St. Maisuri T Chalid

Abstract Objective: to find out  the correlation between lipid profille at trimester II of pregnancy and the incidence.of preeclampsia Method : The research  was conducted in the Polyclinic of Hasanuddin University Teaching Hospital, Department of Obstetrics and Gynecology of the Faculty of Medicine, and it network in Makassar city from March, 2015 through March, 2016. The research used was the prospective cohort design. Results : The examination of the lipid levels of 115 pregnant mothers, aged 24-28 weeks. The mothers were then observed whether they experienced preeclampsia up to the time they gave birth or not. In the end, 8 subjects (6.9%) experienced preeclampsia and 107 subjects (93.1%) have no preeclampsia. The statistical analyses used Fisher’s Exact test and Mann Whitney test. The research results indicated that the mean value of the total cholesterol and Low Density Lipoprotein (LDL) was higher in the preeclampsia group compared to the non-preeclampsia group: 267.37 ± 64.12 : 238 ± 37.98; 177.38 ± 55.38 : 157.24 ± 35.08 (p>0.05). The mean value of High Density Lipoprotein (HDL) was lower in the preeclampsia group compared to the non-preeclampsia group: 64.75 ± 14.64 : 67.86 ± 16.72 (p>0,05). The mean value of trigliserida in preeclampsia group was significantly higher (19,5%) compared thanin the non-preeclampsia group: 260.12 ± 58.86 vs 209.14 ± 65.10 (p=0,027). Conclusion : The hypertrigliseridemia was correlated with the preeclampsia incidence. Keywords:preeclampsia, lipid profile, trimester II of pregnancy   Abstrak Tujuan: mengetahui hubungan antara profil lipid kehamilan trimester II dengan kejadian preeklamsia. Metode : Penelitian dilaksanakan di Poliklinik RS jejaring pendidikan Departemen Obstetri dan Ginekologi Fakulltas Kedokteran Universitas Hasanuddin dan Poliklinik Kesehatan Ibu dan Anak di beberapa Puskesmas Kota Makassar selama Maret 2015 sampai dengan Maret 2016. Rancangan penelitian yang digunakan adalah prospektif  kohort. Hasil: dari 115 ibu hamil dilakukan pemeriksaan  kadar lipid, 115 ibu hamil pada usia kehamilan 24 – 28 minggu, kemudian diamati apakah subyek mengalami preeklamsia hingga proses persalinan. Terdapat delapan subyek (6,9%) berkembang menjadi preeklampsia dan 107 subyek tidak preeklamsia. Data dianalisis secara statistik dengan menggunakan uji Fisher’s Exact dan uji Mann Whitney. Hasil penelitian menunjukkan bahwa nilai mean kolesterol total dan Low Density Lipoprotein (LDL) lebih tinggi pada kelompok preeklampsia dibandingkan kelompok tidak preeklamsia, yaitu 267,37 ± 64,12 : 238,01 ± 37,98; 177,38 ± 55,38 : 157,24 ± 35,08 (p>0,05). Nilai mean High Density Lipoprotein (HDL) lebih rendah pada kelompok preeklamsia dibandingkan tidak preeklamsia yaitu 64,75 ± 14,64 : 67,86 ± 16,72 (p>0,05). Nilai mean trigli seri daripada kelompok preeklamsia secara signifikan lebih tinggi 19,5 % dibandingkan kelompok tidak preeklamsia, yaitu 260,12 ± 58,86 : 209,14 ± 65,10 (p=0,027). Kesimpulan : Hiper trigli seridemia berhubungan dengan kejadian preeklamsia. Kata kunci : preeklamsia, profil lipid, kehamilan trimester II    


2021 ◽  
Vol 6 (15) ◽  
pp. 80-86
Author(s):  
Serhat Çalışkan ◽  
Mehmet ATAY ◽  
Ferit BÖYÜK

Objective: In our study, it was aimed to evaluate the relationship between neutrophil/lymphocyte, monocyte/high-density lipoprotein and magnesium/phosphate ratios with endothelial functions in patients with peripheral artery disease. Methods: Sixty patients followed up with peripheral arterial disease were included in this study. Endothelial functions of the patients were evaluated by flow-mediated vasodilation test. Pearson correlation analysis was used to evaluate the relationship between magnesium/phosphate, neutrophil/lymphocyte, monocyte/high-density lipoprotein ratios with percent change in flow-mediated vasodilation. Results: 48.3% of the participants are male and 51.7% are female. The mean age of the patients were 66.85±11.08 years. The mean radial artery basal diameter was 0.24±0.02 cm in the flow-mediated vasodilatation test and after the test the mean radial artery diameter was 0.27±0.02 cm(p<0.001). In the flow-mediated dilatation test predicting endothelial functions, the percentage change in arterial diameter was positively correlated with the Magnesium/phosphate ratio (r=-0.326, p=0.011), and negatively correlated with the Neutrophil/lymphocyte ratio and monocyte/high-density lipoprotein ratio (respectively r= -0.411, p=0.001; r=-0.530, p=0.001). Conclusion: Magnesium/phosphate ratio, neutrophil/lymphocyte ratio and monocyte/high-density lipoprotein ratio can be used to predict endothelial dysfunction in patients with peripheral artery disease.


1980 ◽  
Vol 26 (9) ◽  
pp. 1275-1277 ◽  
Author(s):  
Y Yamaguchi

Abstract I describe a method for measuring high-density lipoprotein phospholipids. Magnesium chloride and dextran sulfate are used to precipitate all low-density and very-low-density lipoproteins. The supernate contains only high-density lipoproteins, the phospholipid concentration of which is determined by an enzymic method. The precision of the method (CV) is 2.35% (10 repeated assays), and the mean value for HDL-phospholipids was 1006 (SD 248) mg/L for 30 apparently healthy subjects. I used electrophoresis and enzymic color development to confirm the presence of HDL-phospholipids. Results are compared with those obtained by an ultracentrifugation method.


Author(s):  
Chun-Sheng Hsu ◽  
Shin-Tsu Chang ◽  
Oswald Ndi Nfor ◽  
Kuan-Jung Lee ◽  
Shiuan-Shinn Lee ◽  
...  

Increased levels of high-density lipoprotein cholesterol (HDL-C) can improve endothelial function. This may help reduce cardiovascular risks and mortality. Evidence has been provided on the association between cardiometabolic traits, such as HDL-C and exercise modalities. However, there is the absence of studies investigating this association in Taiwan. We assessed the relationship between exercise type and HDL-C among Taiwanese adults. Data were collected from Taiwan Biobank (TWB), a national biomedical research database that contains the genetic information of ethnic Taiwanese residents gathered from 2008 to 2016. We enrolled 24,856 participants aged 30 to 70 years who completed a questionnaire about their recent health behaviors including smoking, drinking, and exercise. Regular exercise was categorized as non-aerobic exercise (separated as weight training, ball game, and mixed exercise) and strict aerobic exercise. Linear regression models were used to assess the effects of exercise in a questionnaire-based manner. After multivariate adjustments, HDL-C was positively associated with aerobic (β = 1.33748, p < 0.0001) and non-aerobic (β = 2.56210; p < 0.0001) exercise. Positive associations were also found for resistance training (β = 4.01828, p = 0.0020), ballgame (β = 2.43815, p = 0.0001), and mixed exercise (β = 2.47021, p < 0.0001). This study demonstrated that both aerobic and non-aerobic exercise have positive effects on HDL-C among Taiwanese adults. Among the non-aerobic exercise groups, resistance training had the greatest effect.


1979 ◽  
Vol 25 (7) ◽  
pp. 1309-1313 ◽  
Author(s):  
C Mayfield ◽  
G R Warnick ◽  
J J Albers

Abstract Commercial heparin preparations (18 lots) from seven manufacturers were compared in the heparin-Mn2+ procedure for high-density-lipoprotein cholesterol quantitation. With normotriglyceridemic samples, 16 heparin lots, isolated from porcine intestinal mucosa, gave mean values for supernatant cholesterol that did not differ statistically; all were within 7 mg/L. Two heparin preparations from bovine lung gave results that were slightly (16 mg/L, average) but significantly (p less than 0.005) lower. With hypertriglyceridemic samples, we observed greater variation in supernatant cholesterol among the heparin preparations, which was ascribable to variable sedimentation by centrifugation of very-low-density and low-density lipoproteins precipitated by heparin-Mn2+ treatment. If the precipitated lipoproteins were completely removed by an ultrafiltration procedure, we saw no significant difference among the heparin preparations for results with hypertriglyceridemic samples.


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