scholarly journals 217 PROFIL PIODERMA PADA ANAK DI POLIKLINIK KULIT DAN KELAMINRSUP PROF. DR. R. D. KANDOU MANADO PERIODE JANUARI-DESEMBER 2012

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Caren C.a Pangow ◽  
Herry E. J. Pandaleke ◽  
Renate T. Kandou
Keyword(s):  
Nutritional Status ◽  
Skin Infection ◽  
Skin Diseases ◽  
Topical Therapy ◽  
Secondary Data ◽  
Infected Group ◽  
Number Of Patients ◽  
High Level ◽  
Infectious Skin Diseases ◽  
Systemic Antibiotics

Abstract: Pyoderma is a skin infection caused byeither or both of staphylococcus and streptococcus bacteria. This infectious skin diseases are still the main problem of high level morbidity cases in children, especially indeveloping countries with topical climate including Indonesia. This study’s goal to gain pyoderma patients profile in children at the dermatovenereology clinic of Prof. Dr R. D. Kandou General Hospital Manado during the period from January - December 2012. This is a retrospectivedescriptive study from the secondary data of pyoderma’spatient in children, based on the number of patients, sex, age, diagnose, nutritional status, and therapy. The results showed that of pyoderma’s cases in children during January - Decemberwas fifty three cases (16,51%). The distribution based on sex mostly on female (56,6%), based on age infected group mostly on 1-4 years old (43,4%). The majortypes of pyoderma isimpetigo (58,5%). The distributionbased on nutritional status mostly on well-nourished (64,7%). There were thirty fivepatients (66%) givensystemic antibiotic with topical therapy.The most systemic antibiotics therapy used was erythromycin (62,2%), and the most topical therapy used was fusidic acid (34 %).Keywords: pyoderma, childrenAbstrak: Pioderma adalah infeksi kulit yang disebabkan oleh kuman staphylococcus, streptococcus atau keduanya.Penyakit infeksi kulit masih merupakan masalah utama penyebab tingginya angka morbiditas pada anak-anak terutama di negara-negara berkembang dan wilayah beriklim tropis, termasuk di Indonesia.Tujuan penelitian ini untuk mengetahui profil pasien pioderma pada anak di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2012 – Desember 2012. Penelitian ini merupakan penelitian deskriptif retrospektif dari data sekunder pasien pioderma anak (umur 0-14 tahun) berdasarkan jumlah pasien, umur, jenis kelamin, diagnosis, status gizi, dan terapi. Hasil penelitian menunjukkan bahwa pioderma pada anak periode januari – desember 2012 sebanyak 53 kasus (16,51%). Distribusi menurut jenis kelamin terbanyak pada perempuan (35,6 %) dan menurut umur terbanyak adalah kelompok umur 1-4 tahun (43,4%). Jenis pioderma terbanyak adalah impetigo (58,5%). Distribusi menurut status gizi terbanyak adalah bergizi baik (64,7%). Sebanyak 35 pasien (66%) diberikan terapi antibiotik sistemik dengan topikal. Terapi antibiotik sistemik terbanyak yang digunakan adalah eritromisin (62,2%), dan topikal yang paling sering digunakan adalah asam fusidat (34%).Kata kunci: pioderma, anak

scholarly journals Prevalence study of dermatoses referred to the phototherapy unit at the Dermatology Service of the Clinics Hospital of Porto Alegre, RS, Brazil

2013 ◽  
Vol 88 (2) ◽  
pp. 211-215 ◽  
Author(s):  
Carolina Casara ◽  
Leticia Eidt ◽  
Vivian Cunha
Keyword(s):  
Skin Diseases ◽  
Uv Light ◽  
Secondary Data ◽  
Cross Sectional Study ◽  
Study Data ◽  
Porto Alegre ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Long Time ◽  
Official Data

BACKGROUND: Phototherapy consists of exposure to ultraviolet radiation for therapeutic reasons. Radiation is already used in dermatological practice, and many studies have already proved the beneficial effect of UV light treatment for chronic inflammatory or lymphoproliferative skin diseases. The Dermatology Service of the Clinics Hospital of Porto Alegre (Hospital de Clínicas de Porto Alegre) has been using phototherapy for a long time, and no official data have been described so far. OBJECTIVES: To study the prevalence of dermatoses referred to the phototherapy unit at the Clinics Hospital of Porto Alegre and describe the total number of patients who have already been referred to this sector and their phototype. METHODS: This is a descriptive cross-sectional study. Data were collected through a review of the phototherapy patients' records (secondary data), which are available on a database of the Dermatology Service of the Clinics Hospital of Porto Alegre, from August 1997 to July 2011. RESULTS: A total of 653 records were analyzed. Phototype 3 was the most prevalent (n=313). Distribution of the prevalence of dermatoses referred to the phototherapy unit was as follows: vitiligo (279), psoriasis (255), cutaneous T-cell lymphoma/mycosis fungoides (29), graftversus-host disease (15), scleroderma (11), atopic dermatitis (10), alopecia areata (6), parapsoriasis (5), eczema (4), granuloma annulare (4), and others (35). As vitiligo and psoriasis were the two most prevalent dermatoses, they were analyzed separately, with no statistical difference in prevalence between them (P=0,177). CONCLUSIONS: Our findings are in accordance with the literature, showing that although phototherapy is still mostly indicated to treat psoriasis, it has been used to treat other dermatoses, since the results are promising.

Cytokine response to killed Staphylococcus pseudintermedius antigen in dogs with skin diseases

2019 ◽  
Author(s):  
M. Ananda Chitra ◽  
Hridya Susan Varughese ◽  
Ranjani Rajasekaran ◽  
S. Rajalakshmi ◽  
G. Dhinakar Raj
Keyword(s):  
Quantitative Pcr ◽  
Skin Infection ◽  
Skin Diseases ◽  
Housekeeping Gene ◽  
The Other ◽  
Measurable Quantity ◽  
Th2 Response ◽  
Healthy Control ◽  
Underlying Causes ◽  
High Level

The attempt was made to study the response of the dog having skin infection with various underlying causes to killed S.pseudintermedius antigen. PBMC were separated and sensitized with killed S. pseudintermedius for 24 hours. cDNA was made from extracted RNA and quantitative PCR were carried out for 8 cytokines with GAPDH as housekeeping gene. IL-6 was the cytokine which was expressed in a statistically significant high level in PBMC of healthy animals to killed antigen than PBMC of infected animals. Except for the IL-6, all other cytokines were expressed at high level in pyoderma animals than healthy control, demodicosis and allergy cases. In the present study, IL-1â, IL-8 and TNF-á were the cytokines that were up-regulated and, IL-6 and IFN-ã were down-regulated in demodicosis dogs with pyoderma at apparently significant level than the other tested cytokines. IL-4 was the only cytokine that was expressed in measurable quantity in allergic cases when compared to other cytokines. Thus, it was concluded that dogs with staphylococcal pyoderma infections developed a Th1/Th2 response to fight the infection.

Nutrition Status of School Children in Punjab, India: Findings from School Health Surveys

2020 ◽  
Author(s):  
Madhur Verma ◽  
Priyanka Sharma ◽  
Poonam Khanna ◽  
Rachana Srivastava ◽  
Soumya Swaroop Sahoo
Keyword(s):  
Data Analysis ◽  
Nutritional Status ◽  
Children And Adolescents ◽  
Middle Childhood ◽  
Secondary Data ◽  
Nutrition Status ◽  
Age Group ◽  
Nutrition Interventions ◽  
Intergenerational Cycle ◽  
High Level

Abstract Background School-going children and adolescents are rarely targeted in nutrition surveys, despite the significant impact of nutritional status on their health, cognition, educational achievements and future economic productivity. The present secondary data analysis evaluated the nutritional status of children and adolescents in the 5–18 years age group. Materials and methods The anthropometric measurements of children and adolescents studying in the government and government-aided schools were collected under the ‘Rashtriya Bal Swasthya Karyakram’ in the District Fatehgarh Sahib of Punjab, India between March and August 2018. It was analyzed using SPSS version 21. Mean and standard deviation for weight-for-age, height-for-age, body mass index (BMI) for age z-scores were calculated using World Health Organization’s Anthro-plus software. Results A total of 897 children’s data were included in the study. Out of 352 children in 5–9 years age group, mean weight, height and BMI were 15.7 ± 3.8 kg, 110.7 ± 10.6 cm and 12.7 ± 2.1 kg/m2. About 58.8%, 37.4% and 31.8% of the children were categorized as severely underweight, stunted and thin, respectively. In the 10–18 years age group, mean weight, height and BMI were 30.5 ± 9.5 kg, 140 ± 13.4 cm and 15.2 ± 2.6 kg/m2. Severe stunting was present in 19.4% of adolescents, while 26.9% were severely thin. Conclusion Our study depicts a high level of undernutrition in school-going children and adolescents. There is a need to strengthen the nutrition interventions for middle childhood and adolescence period that can help in a healthy transition from childhood to adulthood and break the intergenerational cycle of malnutrition. Lay summary National and state-level health-priorities focus mainly on improving the nutrition status of under-5-year children, while the school-going children and adolescents are usually neglected. The present secondary data analysis estimates the burden of malnutrition in school-going children and adolescents. These data were collected under one of India's national health programs that intend to tackle childhood illnesses. Our study depicts a high level of undernutrition in school-going children and adolescents. We found that girls were affected more by malnutrition in middle childhood, i.e. during 5–9 years (both by stunting and thinness) compared to boys. But in middle and late adolescence, males were more stunted and thin compared to females. Programs to support adolescents' nutrition interventions could provide an opportunity for a healthy transition from childhood to adulthood and could be an essential step in breaking the intergenerational cycle of malnutrition.

scholarly journals Dermatovenereology of Russian Federation in 2020: Working Under a Pandemic

2021 ◽  
Vol 97 (4) ◽  
pp. 8-32
Author(s):  
Alexey A. Kubanov ◽  
Elena V. Bogdanova
Keyword(s):  
Medical Care ◽  
Russian Federation ◽  
Skin Diseases ◽  
Subcutaneous Tissue ◽  
Incidence Rates ◽  
Sexually Transmitted ◽  
Number Of Patients ◽  
Day Hospitals ◽  
Infectious Skin Diseases ◽  
The Impact

The article presents an analysis of the resources and activities of medical organizations providing medical care in the field of dermatovenereology for the period 20152020. Up-to-date data on the number of medical organizations and units providing specialized medical care in the field of dermatovenereology are provided. A description of the main changes in the provision of the population of the Russian Federation with dermatovenereologists, staffing with dermatovenereologists of medical organizations is given. Changes in the number of outpatient visits in 2020 are given. The dynamics of the bed fund of 24-hour and day hospitals of a dermatovenereological profile, the bed occupancy, the number of patients treated is described. The data on the incidence of sexually transmitted infections, infectious skin diseases are presented. Prevalence and incidence rates of diseases of the skin and subcutaneous tissue, including atopic dermatitis and psoriasis, are given. The impact of measures aimed at preventing the spread of a new coronavirus infection and organizing the provision of medical care to patients with COVID-19 on the performance rates of dermatovenereologic medical organizations has been demonstrated.

Fusidic Acid and Infectious Skin Diseases

1974 ◽  
Vol 36 (3) ◽  
pp. 403-410 ◽  
Author(s):  
Tadahiko MATSUMOTO ◽  
Michiyasu ARIYOSHI ◽  
Yuwao HINO
Keyword(s):  
Fusidic Acid ◽  
Skin Diseases ◽  
Infectious Skin Diseases

Topical Lipid Based Drug Delivery Systems for Skin Diseases: A Review

2020 ◽  
Vol 15 (4) ◽  
pp. 283-298
Author(s):  
Suresh Kumar Sahu ◽  
Rakesh Raj ◽  
Pooja Mongia Raj ◽  
Ram Alpana
Keyword(s):  
Drug Delivery ◽  
Skin Diseases ◽  
Topical Therapy ◽  
Skin Layer ◽  
Dosage Forms ◽  
Delivery Systems ◽  
Systemic Side Effects ◽  
Transcutaneous Delivery ◽  
Topical Dosage ◽  
Topical Dosage Forms

Treatment of skin ailments through systemic administration is limited due to toxicity and patients discomfort. Hence, lower risk of systemic side effects from topical dosage forms like ointments, creams, emulsions and gels is more preferred for the treatment of skin disease. Application of lipid based carriers in drug delivery in topical formulations has recently become one of the major approaches to improve drug permeation, safety, and effectiveness. These delivery systems include liposomes, ethosomes, transfersomes, Nanoemulsions (NEs), Solid Lipid Nanoparticles (SLNs) Nanostructured Lipid Carriers (NLCs) and micelles. Most of the liposomes and SLNs based products are in the market while some are under investigation. Transcutaneous delivery of therapeutics to the skin layer by novel lipid based carriers has enhanced topical therapy for the treatment of skin ailments. This article covers an overview of the lipid-based carriers for topical uses to alleviate skin diseases.

scholarly journals AI-based localization and classification of skin disease with erythema

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ha Min Son ◽  
Wooho Jeon ◽  
Jinhyun Kim ◽  
Chan Yeong Heo ◽  
Hye Jin Yoon ◽  
...  
Keyword(s):  
Neural Network ◽  
Skin Diseases ◽  
Classification Model ◽  
Screening Tests ◽  
Sensitivity Score ◽  
Common Skin ◽  
Novel Method ◽  
Improved Performance ◽  
High Level

AbstractAlthough computer-aided diagnosis (CAD) is used to improve the quality of diagnosis in various medical fields such as mammography and colonography, it is not used in dermatology, where noninvasive screening tests are performed only with the naked eye, and avoidable inaccuracies may exist. This study shows that CAD may also be a viable option in dermatology by presenting a novel method to sequentially combine accurate segmentation and classification models. Given an image of the skin, we decompose the image to normalize and extract high-level features. Using a neural network-based segmentation model to create a segmented map of the image, we then cluster sections of abnormal skin and pass this information to a classification model. We classify each cluster into different common skin diseases using another neural network model. Our segmentation model achieves better performance compared to previous studies, and also achieves a near-perfect sensitivity score in unfavorable conditions. Our classification model is more accurate than a baseline model trained without segmentation, while also being able to classify multiple diseases within a single image. This improved performance may be sufficient to use CAD in the field of dermatology.

scholarly journals Treatment of acne and acne-related scarring with fixed combination clindamycin phosphate and benzoyl peroxide gel (1.2%/3.75%) and tretinoin gel microsphere 0.06% in an Asian American transgender female

2020 ◽  
Vol 8 ◽  
pp. 2050313X2098403
Author(s):  
Edidiong CN Kaminska
Keyword(s):  
Benzoyl Peroxide ◽  
Asian American ◽  
Skin Diseases ◽  
Fixed Combination ◽  
Acne Vulgaris ◽  
Topical Therapy ◽  
The United States ◽  
Clindamycin Phosphate ◽  
Common Skin ◽  
Group Post

Acne vulgaris is one of the most common skin diseases in the United States and can affect any gender or ethnic group. Post-inflammatory hyperpigmentation (PIH) and scarring from acne can have a negative psychosocial impact on patients. Skin of color patients are particularly prone to PIH, as the dark marks left from acne may take several months to resolve, far after the acne has cleared. Here, we report a case of moderate acne with associated scarring in a transgender, Asian American female who was successfully treated with fixed combination topical therapy with clindamycin phosphate and benzoyl peroxide gel 1.2%/3.75% and tretinoin gel microsphere 0.06%.

scholarly journals Changes in Age at Diagnosis and Nutritional Course of Celiac Disease in the Last Two Decades

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 156 ◽  
Author(s):  
Mónica Villanueva ◽  
Amaya Oyarzún ◽  
Bárbara Leyton ◽  
Mónica González ◽  
Elizabeth Navarro ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Nutritional Status ◽  
Gastrointestinal Symptoms ◽  
Failure To Thrive ◽  
Age At Diagnosis ◽  
Pediatric Hospitals ◽  
Geographical Variations ◽  
Number Of Patients ◽  
Antiendomysial Antibodies

The frequency of celiac disease (CD) has increased along time, with relevant changes reported in geographical variations, clinical presentation and nutritional repercussions. In recent years, some celiac patients are presenting overweight/obesity, but it is unclear how frequent this is and to what extent undernutrition remains a concern. This is relevant because CD tends to be overlooked in overweight patients. With this in mind, we assessed age at diagnosis, clinical characteristics and nutritional status of 155 celiac patients diagnosed between 1994–2017 in four pediatric hospitals in Santiago, Chile. Since 2003, the number of patients diagnosed has increased (p < 0.0033), coinciding with antitransglutaminase and antiendomysial antibodies becoming available to public health systems. In 2000, 4.5% of patients were asymptomatic at diagnosis, suggesting that active search is not routinely applied. Gastrointestinal symptoms plus failure to thrive were significantly more frequent under 2 years (p = 0.0001). Nutritional status has improved at diagnosis and during follow up, but undernutrition remains more frequent in children <2 and <5 years (p < 0.002 and p < 0.0036, respectively). Overweight at diagnosis was reported in 2002 and obesity in 2010. After initiating treatment, since 2010, patients changing from undernourishment to overweight has sometimes been observed after only 6 months on a gluten-free diet.

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