scholarly journals A Smart System to Ease Occurrence of Bedsores

2021 ◽  
Vol 3 (3) ◽  
pp. 156-163
Author(s):  
Benjamin Kommey
Keyword(s):  
Constant Pressure ◽  
The Body ◽  
Pressure Sores ◽  
Time Intervals ◽  
Smart System ◽  
Turn On ◽  
Skin Contact ◽  
Long Time ◽  
Weight Sensor ◽  
Bedridden Patient

The occurrence of bedsores in Ghanaian hospitals, elderly homes or care homes is especially high among patients or people who are incapacitated and cannot move or turn on their own, and who happen to remain in a particular posture for a very long time. Patients in coma, those operated on and for that matter in critical state, and patients confined to wheelchairs are primary examples. Constant pressure on some parts of the body leads to the occurrence of pressure sores or ulcers. This paper seeks to implement a Bedsore Easing System (BeSoSys) that integrate several embedded hardware components, a database and software to reduce the occurrence of bedsores. These embedded hardware components include the Bed Device Unit (BDU), the Pocket Device Unit (PDU), a pressure or weight sensor, a temperature sensor, and an inflation-deflation device. The BDU is fitted into the bed of the patient or on the surface of skin contact of the patient. The PDU is assigned to nurses or caretakers to serve as an alarm system for patient repositioning depending on situation. All activities in the Bedsore Easing System are logged into a database for future references. A bedridden patient exerts constant pressure on the bony protrusions of the body, and this causes bedsores. It was found out during the research that in Ghana, the nurses or caretakers used to turn and massage patients at some random time intervals as a way of preventing bedsores. This traditional way of turning and massaging patients is not only tedious but also ineffective. This paper seeks to provide easy, better, and effective solution to ease bedsores. The BeSoSys intends to prevent the occurrence of bedsores hence the alleviation of bedsore complications

Super-Fine Structure in the Critical Flow-Rate of Critical Flow Venturi Nozzles

2002 ◽  
Author(s):  
Masahiro Ishibashi
Keyword(s):  
Fine Structure ◽  
Steady State ◽  
Discharge Coefficient ◽  
Constant Pressure ◽  
Pressure Ratio ◽  
Critical Flow ◽  
Time Intervals ◽  
Critical Flow Rate ◽  
A Value ◽  
Long Time

It is shown that critical flow Venturi nozzles need time intervals, i.e., more than five hours, to achieve steady state conditions. During these intervals, the discharge coefficient varies gradually to reach a value inherent to the pressure ratio applied. When a nozzle is suddenly put in the critical condition, its discharge coefficient is trapped at a certain value then afterwards approaches gradually to the inherent value. Primary calibrations are considered to have measured the trapped discharge coefficient, whereas nozzles in applications, where a constant pressure ratio is applied for a long time, have a discharge coefficient inherent to the pressure ratio; inherent and trapped coefficients can differ by 0.03–0.04%.

scholarly journals Arogyakrpata - A Natural Protection

2020 ◽  
Vol 06 (9S) ◽  
pp. 147-153
Author(s):  
Saloni Jain
Keyword(s):  
Medicinal Plants ◽  
The Body ◽  
Environment Friendly ◽  
Care Givers ◽  
Skin Contact ◽  
The People ◽  
Safety And Health ◽  
Long Time ◽  
Natural Protection ◽  
Fabric Production

During this present situation of pandemic (COVID-19), it is really important for people’s wellbeing and to take care of their health and immunity. Since no vaccine has been discovered to cure/ effectively available to the people, the effect of the virus is outnumbering the other illness of previous pandemic. The research is designed towards the wellbeing of the Covid-affected population by designing bed linen and medicated patient’s robe. Therefore, the aim of the design here is to solve the area of design problem of Corona affected patients and recovering population in quarantine, either in medical facility centers or at home isolation. The design of ArogyakrpaTa - textile products includes products likes bed cover, cushion and Patient’s robe and overall/ apron for care givers. The design solutions are aimed to address the safety and health- aspect of the concern patients. Using medicinal plants Improving the immunity of a person by giving some level of protection from falling sick from even a normal bacteria or flu. Using herbal medicinal plants and their benefits by dying and covering to create a home collection/wearable piece/ fashion which helps not only as a protection but also it will develop a goodaroma on the skin, and one will notice immunity creating in the body. Also the absence of harsh chemicals in terms of dye stuff and textile finishing, is going to be beneficial for long time use, specially most of the skin contact time with patient’s bed sheet and pillow cover will be more than 12 to 24 hours for initial weeks and approx. 14 hours for the laterperiod of the time.The fibers of the material used to develop the fabric are obtained naturally, is environment friendly, sustainable and biodegradable. The fibers are long, soft, shiny and can be spun into coarse, strong threads and also is biodegradable. The medicinal dye can be used after the yarn process or after the fabric production process. Protection masks can also be developed with it.

scholarly journals Development of Novel Oral Formulations of Disulfide Antioxidants Based on Porous Silica for Controlled Release of the Drugs

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 963
Author(s):  
Ekaterina S. Dolinina ◽  
Elena V. Parfenyuk
Keyword(s):  
Antioxidant Activity ◽  
Surface Chemistry ◽  
Sol Gel ◽  
Porous Silica ◽  
The Body ◽  
Oral Drug ◽  
Therapeutic Concentration ◽  
Release Process ◽  
Zero Order Kinetics ◽  
Long Time

Powerful antioxidant α-lipoic acid (LA) exhibits limited therapeutic efficiency due to its pharmacokinetic properties. Therefore, the purpose of this work was to evaluate the ability of silica-based composites of LA as well as its amide (lipoamide, LM), as new oral drug formulations, to control their release and maintain their therapeutic concentration and antioxidant activity in the body over a long time. The composites synthesized at different sol–gel synthesis pH and based on silica matrixes with various surface chemistry were investigated. The release behavior of the composites in media mimicking pH of digestive fluids (pH 1.6, 6.8, and 7.4) was revealed. The effects of chemical structure of the antioxidants, synthesis pH, surface chemistry of the silica matrixes in the composites as well as the pH of release medium on kinetic parameters of the drug release and mechanisms of the process were discussed. The comparative analysis of the obtained data allowed the determination of the most promising composites. Using these composites, modeling of the release process of the antioxidants in accordance with transit conditions of the drugs in stomach, proximal, and distal parts of small intestine and colon was carried out. The composites exhibited the release close to the zero order kinetics and maintained the therapeutic concentration of the drugs and antioxidant effect in all parts of the intestine for up to 24 h. The obtained results showed that encapsulation of LA and LM in the silica matrixes is a promising way to improve their bioavailability and antioxidant activity.

scholarly journals Optimal Perturbations of an Oceanic Vortex Lens

Fluids ◽  
2018 ◽  
Vol 3 (3) ◽  
pp. 63 ◽  
Author(s):  
Thomas Meunier ◽  
Claire Ménesguen ◽  
Xavier Carton ◽  
Sylvie Le Gentil ◽  
Richard Schopp
Keyword(s):  
Normal Mode ◽  
Growth Rates ◽  
Time Interval ◽  
Time Intervals ◽  
Horizontal Structure ◽  
Azimuthal Wave ◽  
Wave Numbers ◽  
Non Linear ◽  
Long Time ◽  
Short Time

The stability properties of a vortex lens are studied in the quasi geostrophic (QG) framework using the generalized stability theory. Optimal perturbations are obtained using a tangent linear QG model and its adjoint. Their fine-scale spatial structures are studied in details. Growth rates of optimal perturbations are shown to be extremely sensitive to the time interval of optimization: The most unstable perturbations are found for time intervals of about 3 days, while the growth rates continuously decrease towards the most unstable normal mode, which is reached after about 170 days. The horizontal structure of the optimal perturbations consists of an intense counter-shear spiralling. It is also extremely sensitive to time interval: for short time intervals, the optimal perturbations are made of a broad spectrum of high azimuthal wave numbers. As the time interval increases, only low azimuthal wave numbers are found. The vertical structures of optimal perturbations exhibit strong layering associated with high vertical wave numbers whatever the time interval. However, the latter parameter plays an important role in the width of the vertical spectrum of the perturbation: short time interval perturbations have a narrow vertical spectrum while long time interval perturbations show a broad range of vertical scales. Optimal perturbations were set as initial perturbations of the vortex lens in a fully non linear QG model. It appears that for short time intervals, the perturbations decay after an initial transient growth, while for longer time intervals, the optimal perturbation keeps on growing, quickly leading to a non-linear regime or exciting lower azimuthal modes, consistent with normal mode instability. Very long time intervals simply behave like the most unstable normal mode. The possible impact of optimal perturbations on layering is also discussed.

scholarly journals Mangiferin as New Potential Anti-Cancer Agent and Mangiferin-Integrated Polymer Systems—A Novel Research Direction

Biomolecules ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 79
Author(s):  
Svetlana N. Morozkina ◽  
Thi Hong Nhung Vu ◽  
Yuliya E. Generalova ◽  
Petr P. Snetkov ◽  
Mayya V. Uspenskaya
Keyword(s):  
Molecular Mechanisms ◽  
Biological Activities ◽  
Research Direction ◽  
Biological Action ◽  
The Body ◽  
Biologically Active ◽  
Polymer Systems ◽  
Anti Cancer ◽  
Long Time ◽  
Cancer Agent

For a long time, the pharmaceutical industry focused on natural biologically active molecules due to their unique properties, availability and significantly less side-effects. Mangiferin is a naturally occurring C-glucosylxantone that has substantial potential for the treatment of various diseases thanks to its numerous biological activities. Many research studies have proven that mangiferin possesses antioxidant, anti-infection, anti-cancer, anti-diabetic, cardiovascular, neuroprotective properties and it also increases immunity. It is especially important that it has no toxicity. However, mangiferin is not being currently applied to clinical use because its oral bioavailability as well as its absorption in the body are too low. To improve the solubility, enhance the biological action and bioavailability, mangiferin integrated polymer systems have been developed. In this paper, we review molecular mechanisms of anti-cancer action as well as a number of designed polymer-mangiferin systems. Taking together, mangiferin is a very promising anti-cancer molecule with excellent properties and the absence of toxicity.

VI. The glucoside constitution of proteid matter

1894 ◽  
Vol 54 (326-330) ◽  
pp. 53-57 ◽  
Keyword(s):  
Sulphuric Acid ◽  
Cupric Oxide ◽  
The Body ◽  
Long Time

For a long time I have adopted a process for separating the glycogen of the liver consisting in boiling with potash, pouring into alcohol, and collecting the precipitate. For the purpose of estimation, the precipitated glycogen was converted by means of sulphuric acid into glucose, the determination of which gave the information required. I afterwards applied the process to blood, and the various organs and tissues of the body, with the result that a more or less notable amount of cupric oxide reducing product was obtained, which I at the time looked upon as taking origin, as in the case of the liver, from glycogen.

CHRONIC ATYPICAL NEUTROPHILIC DERMATOSIS WITH LIPODYSTROPHY AND FEVER (CANDLE SYNDROME) IN PEDIATRIC PRACTICE

2021 ◽  
Vol 100 (2) ◽  
pp. 254-261
Author(s):  
O.G. Sukhovjova ◽  
◽  
I.A. Ivanova ◽  
N.A. Kalugina ◽  
E.S. Zholobova ◽  
...  
Keyword(s):  
Clinical Observation ◽  
Clinical Manifestations ◽  
Maculopapular Rash ◽  
The Body ◽  
Neutrophilic Dermatosis ◽  
Inherited Disease ◽  
Laboratory Activity ◽  
Ubiquitinated Proteins ◽  
Systemic Inflammatory Reaction ◽  
Long Time

The purpose of this publication is to describe the CANDLE syndrome (its etiology, pathogenesis, clinical manifestations) and present a clinical observation. CANDLE syndrome is a rare genetically inherited disease caused by impaired assembly by of the protease, which leads to the accumulation of abnormal (ubiquitinated) proteins in B-lymphocytes, fibroblasts, macrophages and some other cells of the body. As a result, an excessive activation of interferon synthesis occurs and a systemic inflammatory reaction develops with symptoms such as febrile fever, skin syndrome, represented by nodules and maculopapular rash, hepatosplenomegaly, lipodystrophy, amyotrophy, delayed physical development, as well as high laboratory activity. The article describes a clinical observation of a female patient with typical symptoms of CANDLE syndrome. However, due to the rarity of the disease and lack of publications describing it, it has not been possible to diagnose the child for a long time.

The Role of Spices with reference Novel Coronavirus Covid 19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1655-1661
Author(s):  
Roshna Sukheoji Bhutada ◽  
Kritika Umate
Keyword(s):  
Viral Infections ◽  
The Body ◽  
Common People ◽  
Supplementary Food ◽  
Long Time ◽  
Novel Coronavirus ◽  
The Right ◽  
Common Spices ◽  
Physiological Reactions

The need of the day is a brisk lift to the resistant framework to keep it fit, battling today pandemic infections, for example, Covid — 19. One should get the right amount of nutrients from the diet, supplementation regimen to boost the immune system. These spices are always there to make tasty food as well as to protect the body from infectious diseases by building the immunity strong Ayurveda approaches to develop physiological reactions to facilitate immunity. Planning of diet is most important to boost immunity. As per many types of research to provide supplementary food which contains Zinc, Vitamin C, Vitamin D and immunity boosting food such as dealing with plenty of spices for a very long time. These spices include some rare to very common spices which we can found near us. The concern is that these viral infections are very prone to attack weak immunity and take the chance to affect the country to the globe. So the very common spices available will be always helpful to get through this Regular use of a few spices in the very simple form proves its importance as a medicine. In this article a review of spices is done which we are available near us, we are using it in our daily life and we are getting the benefit of these which a common people might not be fully aware of about role of immunity building of the body. 

Transplantations de gonades indifférenciées chez l'hermaphrodite simultané Eisenia foetida (Oligochète, Lumbricidae)

Development ◽  
1973 ◽  
Vol 30 (1) ◽  
pp. 143-161
Author(s):  
Par J. C. Relexans
Keyword(s):  
Nervous System ◽  
Sexual Differentiation ◽  
The Body ◽  
Simultaneous Hermaphrodite ◽  
Eisenia Foetida ◽  
Turn On ◽  
Opposite Sex ◽  
Adjacent Wall ◽  
Physiological Gradients ◽  
Different Parts

Transplantations of undifferentiated gonads in the simultaneous hermaphrodite Eisenia foetida (Oligochaeta, Lumbricidae) leading to evidence of local factors (inductors?) of sexual differentiation The hypothesis of a ♀ sex capable of autodifferentiation and of a ♂ sex depending on an androgen hormone has been verified in several gonochoric or hermaphrodite invertebrates. In order to test the validity of this hypothesis in the hermaphrodite Eisenia foetida we have investigated the influence of the gonads' environment on their differentiation by transplanting undifferentiated gonads, dorsally and ventrally, on different parts of the body. The gonads, taken with the adjacent wall of the body from new-born worms, are grafted on worms of the same age; some grafts do, others do not, retain their nervous system. The control transplantation in which a graft of a given presumptive sex is transplanted in a region of the same sex can lead to inversions. These inversions have a rare and short-lived character in the gonads coming from presumptive testes. They are more frequent and more or less durable in the gonads coming from presumptive ovaries. These results can only be explained by the existence, within the grafts of the two presumptive sexes, of a dominant relationship between one and the other sexual potentiality which can be momentarily inverted by trophic disturbances caused by the transplantation. The heterosexual transplantations, in which a graft of a given presumptive sex is transplanted in the region of the opposite sex, show that the frequency of the inversions is doubled in relation to the frequency obtained in the control transplantations. The inversions which occur in the presumptive testes can be lasting and even permanent. These results lead to the opinion that to the effects of transplantation is added an inductive action from the host, leading to masculinity in the ♂ region and femininity in the ♀ region. The transplantations outside of the sexual ventral regions lead to inversions of which the character and frequency recall those obtained in the control transplantations. They suggest that these regions are devoid of inductive sexualizing power. The very slight variations of frequency of the inversions observed along the antero-posterior and dorso-ventral axes can be explained by the existence of physiological gradients acting on the balance of the graft's own potentialities. The removal of the nervous system in the grafts shows that this system plays a part, probably trophic, in favour of the masculine potentialities of the graft. In conclusion, our experiments lead to the rejection of the hypothesis of the ♀ sex capable of autodifferentiation in Eisenia, in order to adopt that of a sexual balance between the ♂ and ♀ potentialities determining, according to their dominant relationship, the synthesis of ♂ or ♀ ‘inductors’ respectively in the ♂ and ♀ ventral regions. These inductors act in turn on the bipotential sexual cells.

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