A STUDY ON “PREVALENCE OF COPD OVERLAP IN ASTHMA PATIENTS–HOSPITAL BASED CROSS SECTIONAL STUDY”

2021 ◽  
pp. 42-44
Author(s):  
S. Hema Akilandeswari ◽  
B. Kavitha ◽  
J. Sudhakaran ◽  
K. Rajkanth

BACKGROUND:Asthma- COPD Overlap Syndrome (ACOS) is a recently dened terminology characterized by persistent limitation in airow, which shares features of both Asthma and COPD. ACOS is associated with worse outcomes than either condition alone. MATERIALS AND METHODS: A cross sectional study conducted in Government Thanjavur Medical College Hospital in the department of Internal Medicine between October 2017 and July 2018. The patients attending the asthma clinic and the medicine op for medications were enrolled into the study. Atotal of 80 patients were included. The statistical analyses were performed using Graph pad Prism version 5 software. RESULTS: In this study it was found that 25 % of the study population had a COPD overlap features. Duration of asthma was found to be a single independent factor associated with the development of COPD overlap in asthmatics in the study population. This study views smoking to have an additive effect in the disease pathology. CONCLUSION: The prevalence of ACOS in previously diagnosed Asthma or COPD is more alarmingly increasing. Asthma- COPD overlap is characterised by more frequent exacerbations and complications. There is a critical need to better dene the management and treatment of this syndrome.

Author(s):  
Atif Ahmed ◽  
Kuldeep Poorani ◽  
Mohammad Amjad Kalhoro ◽  
Nisar Ahmed Khokar ◽  
Abdul Ghaffar Dars

Aim: To study the incidence of HbA1c elevation in patients with ischemic stroke whose blood glucose levels were normal within the last six months. Study Design: A cross-sectional study. Place and Duration: This cross-sectional study of the 96 patients with cerebral ischemic disease selected from the internal medicine department of Bilawal medical college Hospital Kotri, Sindh, Pakistan for one-year duration from August 2019 to August 2020. Methods: Crossectional study was conducted in the internal medicinal department of Bilawal Medical college Hospital, Kotri Sindh, Pakistan for the period of one year from August 2019 to August 2020. Total 96 study subjects were selected with cerebral ischemic disease, 62 were males and 34 were females. Many factors such as age more than 20 years, ischemic stroke and RBG (Random Blood Glucose) were also evaluated from each participant. SPSS 23.00 version was used for statistical analysis of research data. Results: 57.01 ± 13.4 years was the mean age of the patients. 62 (64.6%) patients were male and 34 (35.4%) were female. The male to female ratio was 2:1. HbA1c was elevated in 35 (36.5%) of 96 patients, while 61 (63.5%) had normal HbA1c.  The distribution of HbA1c elevation by gender showed that 20 (57.1%) patients with elevated HbA1c were men and 15 (42.9%) were women. Forty-three (70.5%) of 61 patients with normal HbA1c were male and 18 (29.5%) were female. Conclusion: it was concluded that glycated haemoglobin plays an important role for reducing the macro complication of Diabetes and the major macro complication observed was cerebral ischemic stroke among the people with elevated HbA1c.


Author(s):  
Christina Ann George ◽  
Shibu Thadathil Sreedharan ◽  
Smitha Kalarikkal Satheesan ◽  
Sindhu Panakkaparambil Surendranath

Introduction: Ischaemic Heart Diseases (IHD) are increasing at an alarming rate globally. Pharmacotherapy, the mainstay of management of IHD, has Dual Antiplatelet Therapy (DAPT) at its crux. DAPT, comprising of clopidogrel and aspirin, is used often for 12 months in medically managed Acute Coronary Syndrome (ACS). Clopidogrel being a prodrug, needs to be activated after ingestion, mainly by Cytochrome family of enzymes, for the desired pharmacological effects. Abnormal enzymes that convert clopidogrel to its active form can reduce the effectiveness of the drug. Therefore, Single Nucleotide Polymorphisms (SNPs) of the enzymes involved, would predispose the patient to therapy failure and recurrence of the illness. This study aims at identifying the presence of a genetic variant associated with clopidogrel responsiveness in patients with ACS. Aim: To estimate the frequency of CYP2C19*2 allele in patients with ACS presenting to Government Medical College, Thrissur, Kerala, India. Materials and Methods: Present study was a cross-sectional study done among 60 patients who presented to Government Medical College, Thrissur with ACS, between June 2018 to June 2019. Having obtained informed consent from the participants blood samples were collected in Ethylene diamine tetra-acetic Acid (EDTA) tubes. Samples were used to look for presence of CYP2C19*2 allele by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). Results: Out of 60 patients 38 were males and 22 were females. Most common age group was 61-65 years. The frequency of CYP2C19*2 allele was 41% in the study population and the variant genotype (AA/AG) was present in 62%. Conclusion: The variant genotype was found to be present in a high frequency in the study population implying the high risk for therapy failure in the study population. This asserts the need to probe the matter further, as the gene is also implicated in the metabolism of several other drugs. The introduction of pharmacogenomic testing prior to initiation of therapy may be therefore recommended for better treatment outcome. However, to validate the same, further studies with larger sample size may be necessary.


2014 ◽  
Vol 15 (2) ◽  
pp. 110-113
Author(s):  
Tania Mahbub ◽  
Md. Nizamuddin Chowdhury ◽  
Ferdous Jahan ◽  
Aparna Das ◽  
Md. Motlabur Rahman ◽  
...  

Background: Worldwide haemodialysis(HD) is the mostly used method of renal replacement therapy. Arteriovenous fistula use is on rise due to Fistula First Initiative due to least complications of fistulae than catheters.But they are also subjected to many complications. Thereby appropriate surveillance of the fistulae is important.Objectives: To measure the blood flow as well as fistula related complications in study population. Materials and Methods: This was a cross sectional study, conducted in the department of Nephrology, Dhaka Medical College Hospital during September 2010 to December 2011.Total 118 subjects were included in the study. Besides visualization technique colour Doppler ultrasonogram of fistula and  echocardiography were performed for each patients. Results: Most of the patients had adequate fistula flow. Aneurysm was most common complication. Many subjects were suffered from primary and secondary fistula failure. Conclusion: Arterio-Venous fistula is subjected to many complications and appropriate surveillance should be launched to detect complications and to prevent fistula failure.DOI: http://dx.doi.org/10.3329/jom.v15i2.20681 J MEDICINE 2014; 15 : 110-113


Author(s):  
Tarun Kumar Sarkar ◽  
Pulak Kumar Jana ◽  
Jasmine M. ◽  
Timiresh Kumar Das ◽  
Mrinmoy Adhikary ◽  
...  

Background: Thalassemia is more prevalent in India. The main treatment of Thalassemia is blood transfusion. But the transfusion of blood has many side effects like iron overload, transfusion related infections etc. The objectives of the study were to assess the adequacy of blood transfusion for thalassemic patients and to determine the magnitude of transfusion transmitted infections among those patients.Methods: A cross sectional study was conducted in Murshidabad Medical College and Hospital, West Bengal for 1 month with the sample size of 116. The blood samples from the patients were taken from the patients attending for blood transfusion in transfusion centre of Murshidabad Medical College and Hospital for two weeks dated from 24.04.2017 to 05.05.2017 to check for the hemoglobin, ferritin level and hepatitis B, C and HIV infection.Results: Among the 116 patients, even after transfusion, 94% of the study participants have their hemoglobin levels below 7 gm/dl. Only 2 individuals got their hemoglobin levels more than 9 gm/dl and only 1 patient got HIV infection post transfusion which accounts for 0.9% of study population.Conclusions: Frequent Hb estimation will help to maintain the adequacy of blood transfusion and proper screening of the blood before transfusion can help in reducing these transfusion transmitted infections.


Author(s):  
Ashok Maaan ◽  
Manoj K. Yadav ◽  
S. S. Chaudhary ◽  
Manisha .

Background: Adolescence is a developmental period of rapid physical, psychological, sociocultural, and cognitive changes characterized by efforts to confront and surmount challenges and to establish a sense of identity and autonomy. Objective was to study the sexual behavior practiced by the adolescent and its source of inspiration.Methods: An observational cross-sectional study was carried out in Department of Community Medicine, Santosh Medical College, Ghaziabad and Urban area of district Ghaziabad. 750 Adolescents aged 10 to 19 years studying in the selected schools of urban Ghaziabad were included for the study. The period of study was from November 2011 to October 2012.Results: 26.8% of the students were sexually active. Boys were sexually more active than girls (34.7% vs. 18.9%). Condom use was present in 51.2% of the sexually active students. Nearly half (52.3%) of sexually active males had sex under the influence of pornography, almost one-third (32.3%) had sex merely because of peer pressure and 15.4% did it for curiosity and fun. Among girls who experienced sex 70.4% succumbed to peer pressure and 23.9% under the influence of pornography. In the present study more boys (77.9%) than girls (54.1%) had knowledge about reproductive health issues and this difference between two sexes were found to be statistically significant.Conclusions: The present health status of the study population has the potential possibility of leading to increased health problems for this vulnerable population, in future.


Author(s):  
Subhransu Sekhar Jena ◽  
Binayak Chandra Dwari ◽  
Roopam Panda ◽  
Nibedita Patro

Introduction: Hemiplegia due to cerebral stroke is associated with various dermatological co-morbidities, arising out of motor, sensory and autonomic dysfunctions. Aim: To find out the different dermatological conditions prevalent in patients of hemiplegia secondary to cerebral stroke. Materials and Methods: An observational cross-sectional study was conducted in the Department of Neurology in collaboration with the Department of Dermatology at Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha from July 2017 to June 2020. Patients with hemiplegia of more than one month duration were included. The skin findings present before the neurological insult and patients with systemic conditions like atopic dermatitis, diabetes mellitus and thyroid disorders causing skin changes were excluded. Relevant tests for diagnostic confirmation of the skin lesions were done wherever needed. The software Statistical Package for the Social Sciences (SPSS) version 16.0 was used for the statistical analysis. Results: Study included 411 patients of cerebral stroke. A total of 382 (92.9%) patients were found to have dermatological manifestation. The male:female ratio in the study population was 2.6:1. A total of 549 and 128 skin conditions were diagnosed in the paralysed and non paralysed limbs, respectively. The common dermatological conditions diagnosed in the affected limbs were, xerosis {371 (97.12%)}, tinea corporis/cruris {61 (15.97%)}, onychomycosis {31 (8.12%)}, tinea pedis {28 (7.33%)} and nail dystrophy abnormalities {27 (7.07%)} patients. Conclusion: Knowledge of various dermatological conditions associated with hemiplegia helps in early intervention and better management during rehabilitation phase of patients with hemiplegia.


Author(s):  
C. Rajan Rushender ◽  
G. Dinesh Kumar ◽  
M. Logaraj

Background: Tuberculosis (TB) remains a major public health problem. It is reported that, globally, about 9 million people developed tuberculosis and about 1.5 million people died due to tuberculosis across the globe in 2013.Methods: A descriptive cross sectional study was conducted in the Rural Health Training Center, SRM Medical College to assess knowledge and practice regarding tuberculosis using a pretested Interview schedule. Adult population, who are residing in the field practice area were considered as study population. The study period was between August 2013 to February 2014.Results: A total of 246 study subjects were included in the final analysis with the majority of the participants to be between 21 to 40 years (39.40%). Cough and expectoration as symptom of TB was known to 82.5% of study subjects. Only 22.8% of the study subjects are aware of at least one extra pulmonary for of tuberculosis. The proportion of subjects with good overall knowledge about TB was highest in subjects aged 61 and above, lowest in 41 to 60-year age group. The proportion of subjects with good knowledge had gradually increased with increasing socio economic status.Conclusions: Culture specific IEC interventions and their delivery mechanisms need to be designed, considering the highly heterogeneous nature of population in India. 


2021 ◽  
pp. 96-98
Author(s):  
Nikhil B Chavda ◽  
Kinjal Lathiya ◽  
Devang A Raval ◽  
R.Naredra Kumar ◽  
Hetal Patel ◽  
...  

Road accidents had been a major cause for concern across the Indian subcontinent. In 2019 alone, the country reported over 151 thousand fatalities due to road accidents. Each year, about three to ve percent of the country's GDP was invested in road accidents. Road accidents are on the rise in countries that have experienced signicant and rapid development. This is due to the increased use of automobiles as a result of urbanization and development. A cross-sectional study of undergraduate medical students at a government medical college in Ahmedabad was done. Present study done among 298 under graduate students; out of them 203 were male and 95 were female students. Although the study population had good knowledge regarding trafc rules, only 36.24% were using helmet, 46.31% were using seat belts regularly, 57.72% were using mobile while driving. 76.17% were serviced vehicle properly, 75.84% were slowed down their vehicle when they see yellow light at trafc signal. Almost 98.99 % were using signal to change lane.


2021 ◽  
pp. 161-163
Author(s):  
Hannah Roberts O R ◽  
Saranya Bai S ◽  
Sangeetha N ◽  
Mahendranath P

OBJECTIVE: To determine the awareness and knowledge of blood donation among undergraduate medical students MATERIALS AND METHODS: A cross sectional study was conducted at ACS Medical College and Hospital, Chennai, from st nd rd th January to March 2021.The study population was 400 medical students of 1 , 2 , 3 and 4 year. Pre-tested and self-structured equestionnaire was sent to the study population and the responses were viewed using a separate email id. RESULTS: Of the 400 medical students, 41.5% males and 58.5% females. The mean age is 20.6 years. 368 (92.0 %) are aware of voluntary blood donation. Online platforms or web portals are used by 267 (66.8 %) to assess information about Voluntary Blood Donors. Only 11 (2.7 %) have donated blood regularly. CONCLUSION: We infer that the knowledge and awareness on voluntary blood donation was comparatively higher among males and nal year students. The facts pertaining to voluntary blood donation, when conveyed by the online platforms were found to have greater impact on the current youth generation. Hence, this study recommends organising regular talks and interactive sessions as a must to bridge the gap in knowledge, to identify and remove misconceptions and motivate them for voluntary blood donation on a regular basis.


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