RADIOLOGIC- PATHOLOGIC CORRELATION OF DEPTH OF INVASION IN TONGUE CARCINOMA

2021 ◽  
pp. 27-28
Author(s):  
Pranay Bhandari ◽  
Ashwin Rangole ◽  
Tanuj Shrivastava ◽  
Ameya Bihani ◽  
Pratiksha Pawar
Keyword(s):  
Basement Membrane ◽  
Normal Mucosa ◽  
P Value ◽  
Depth Of Invasion ◽  
Tongue Carcinoma ◽  
Adjacent Normal Mucosa ◽  
Dence Interval ◽  
The Mean ◽  
Group 2 ◽  
Paired T Test

Introduction: th In tongue carcinoma according to AJCC 8 guidelines depth of invasion is included in staging, therefore there is need of imaging which can accurately assess the pretreatment stage of tumor. The objective of this study was to correlate the depth of invasion reporting by MRI and postoperative HPR. Methods: In MRI DOI was measured by drawing perpendicular lines from the reference line to the point of maximal tumor projection in the tongue medially, histologically DOI was measured from the level of the basement membrane of the closest adjacent normal mucosa. Results: Paired t test was done on the DOI of MRI and HPR. The two tailed P value is less than 0.0001. This difference is considered to be extremely statistically signicant. The mean of group one (DOI-MRI) minus Group 2 (DOI-HPR) equals 6.860. 95% condence interval of this difference is from 5.200 to 8.520. Conclusion: In our study we nd there is statiscally signicant difference between DOI reports in MRI and postoperative HPR.

Does Presurgical Nasoalveolar Molding Have a Long-Term Effect on Nasal and Upper Airway Dimensions?

2020 ◽  
pp. 105566562098023
Author(s):  
Ashwina S. Banari ◽  
Sanjeev Datana ◽  
Shiv Shankar Agarwal ◽  
Sujit Kumar Bhandari
Keyword(s):  
Upper Airway ◽  
P Value ◽  
Airway Patency ◽  
The Mean ◽  
Group 2 ◽  
Acoustic Pharyngometry ◽  
Nasoalveolar Molding ◽  
Area And Volume ◽  
Group 1

Objectives: To compare nasal and upper airway dimensions in patients with cleft lip and palate (CLP) who underwent nasoalveolar molding (NAM) with those without NAM during infancy using acoustic pharyngometry and rhinometry. Materials and Methods: Eccovision acoustic pharyngometry and rhinometry (Sleep Group Solutions) was used for assessment of mean area and volume of nasal and upper airway in patients with complete unilateral CLP (age range 16-21 years) treated with NAM (group 1, n = 19) versus without NAM (group 2, n = 22). Results: The mean nasal cross-sectional areas and volume were higher in group 1 compared to group 2 on both cleft ( P value <.001) and noncleft side ( P value >.05). The mean area and volume of upper airway were also significantly higher in group 1 compared to group 2 ( P value <.05). Conclusions: Nasoalveolar molding being one of the first interventions in chronology of treatment of patients with CLP, its long-term outcome on nasal and upper airway patency needs to be ascertained. The results of the present study show that the patients with CLP who have undergone NAM during infancy have better improvement in nasal and upper airway patency compared with those who had not undergone NAM procedure. The basic advantages of being noninvasive, nonionizing and providing dynamic assessment of nasal and upper airway patency make acoustic pharyngometry and rhinometry a diagnostic tool of choice to be used in patients with CLP.

Abstract P42: Active Compression Decompression-CPR in an Infant Manikin Model Using a Novel Adhesive Glove Device

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Sharda Udassi ◽  
Jai P Udassi ◽  
Melissa Lamb ◽  
Doug Theriaque ◽  
Arno L Zaritsky ◽  
...  
Keyword(s):  
Healthcare Providers ◽  
Crossover Design ◽  
P Value ◽  
Compression Pressure ◽  
Compression Depth ◽  
Significant Difference ◽  
The Mean ◽  
Chest Decompression ◽  
Acd Cpr ◽  
Paired T Test

Introduction: In animals Active Compression-Decompression(ACD)-CPR improves hemodynamics compared with standard CPR (S-CPR). We evaluated the feasibility of achieving ACD-CPR with a novel, simple and inexpensive Adhesive Glove Device (AGD) in an infant manikin model using two thumb (TT) chest compression. Hypothesis: AGD-ACD CPR provides better chest decompression compared to S-CPR in an infant manikin model without excessive rescuer fatigue. Methods: Laerdal ™ Baby ALS Trainer manikin was modified to digitally record compression pressure (CP), compression depth (CD) and decompression depth (DD). The thumb portion of two oven mitts were sewn together and a Velcro adhesive patch was stitched on the underside with an encircling adjustable strap for proper fit to create the AGD. An interlocking Velcro patch was glued to the manikin chest wall. Sixteen BLS or PALS certified healthcare providers were prospectively randomized to perform either two-thumb S-CPR or AGD-ACD-CPR for 5 minutes with a 30:2 compression:ventilation ratio using a crossover design. During AGD-ACD-CPR subjects were asked to pull up during chest decompression. Rescuer heart rate (HR), respiratory rate (RR), recovery time (RT) for HR/RR to return to baseline and actual compressions delivered per minute were recorded. Subjects were blinded to data recordings. Data (mean±SEM) was analyzed using 2 sided paired t-test; p-value ≤0.05 was considered significant. Results: Chest decompression was greater with AGD-ACD-CPR; the mean DD difference was 0.11±0.02 inches, p=<0.001. Compressions given per minute were 102±21 in S-CPR group vs. 96±16 in AGD-ACD-CPR group, p=0.04. In AGD-CPR 75% and in S-CPR only 12% of subjects achieved complete recoil to or beyond baseline. There was no significant difference in CD, CP, HR, RR and RT between the groups. Conclusions: Active decompression and improved recoil was achievable with the use of our simple, inexpensive AGD in this infant CPR model. Use of our device did not result in excessive rescuer fatigue compared to S-CPR. The clinical significance of 6 less compressions/minute in the AGD-CPR group needs to be determined.

scholarly journals COMPARISON OF THE EFFECTIVENESS OF TWO LEVELS OF SUCTION PRESSURE ON OXYGEN SATURATION IN PATIENTS WITH ENDOTRACHEAL TUBE

2017 ◽  
Vol 3 (6) ◽  
pp. 693-696
Author(s):  
Muhaji Muhaji ◽  
Bedjo Santoso ◽  
Putrono Putrono
Keyword(s):  
Oxygen Saturation ◽  
T Test ◽  
Mean Difference ◽  
P Value ◽  
Pressure Group ◽  
Endotracheal Suctioning ◽  
Consecutive Sampling ◽  
The Common ◽  
The Mean ◽  
Paired T Test

Background: Endotracheal suctioning is one of the common supportive measures in intensive care units (ICU), which may be related to complications such as hypoxia. However, a questionable efficacy is still identified to choose suctioning pressure between 130 mmHg and 140 mmHg that is effective for patients with endotracheal tube.Objective: To compare the effectiveness of 130 mmHg and 140 mmHg suctioning pressure on oxygen saturation in patients with endotracheal tube.Methods: This research used a quasy experimental design with pretest and posttest group. The study was conducted from 31 January to 1 March 2017 in the Hospital of Panti Wilasa Citarum and Hospital of Roemani Muhammadiyah Semarang. There were 30 samples recruited using consecutive sampling, with 15 assigned in the 130 mmHg and 140 mmHg suctioning pressure group. Pulse oximetry was used to measure oxygen saturation. Paired t-test and Independent t-test were used for data analysis.Results: Findings showed that there was a statistically significant effect of 130 and 140 mmHg suctioning pressure on oxygen saturation in patients with ETT with p-value <0.05. There was a significant mean difference of oxygen saturation between 130 mmHg and 140 mmHg suctioning pressure group with p-value 0.004 (<0.05). The mean difference of oxygen saturation between both groups was 13.157.Conclusion: The 140 mmHg suctioning pressure is more effective compared with 130 mmHg suctioning pressure in increasing oxygen saturation in patients with ETT.

The Effectiveness of Lavender (Lavendula Augustfolia) and Neroli (Citrus Aurantium) Aromatherapy Inhalation to Decrease Pain Labor

2020 ◽  
Vol 6 (1) ◽  
pp. 26-31
Author(s):  
Nurul Azizah ◽  
Rafhani Rosyidah ◽  
Hanik Machfudloh
Keyword(s):  
Labor Pain ◽  
P Value ◽  
Citrus Aurantium ◽  
Uterine Contractions ◽  
Pain Scores ◽  
Quasi Experimental ◽  
The Mean ◽  
Group 2 ◽  
Almost All ◽  
Postpartum Pain

Maternal labor will experience almost all body pain, such as painful ribs, stitches, abdominal pain due to uterine contractions, and discomfort in the back due to epidural needles, and this discomfort will last several days and can be overcome by prescription for painkillers. In this study aimed at carrying out non-famacological pain relief therapy, namely by using aromatherapy which is believed to reduce pain, this study tried to compare the effectiveness of lavender and neroli aromatherapy inhalation to decrease post-labor pain. The research method used quasi-experimental that is given aromatherapy lavender (Lavendula Augustfolia) and neroli (Citrus Aurantium) inhalation treatments. The number of respondents was 60 with 1-2 days of normal and postpartum criteria, each group consisted of 30 respondents. Group 1 was held at the Pearl Delta Clinic RB and group 2 in the Karunia RB Clinic. Data were analyzed by univariable by using mean and standard deviation, bivariable with statistical test independent sample T test. The results of this study showed a mean reduction in pain scores on lavender aromatherapy inhalation of 2.36 ± 0.15, whereas in the aromatherapy neroli inhalation group the mean reduction in pain score was 3.03 ± 0.067 with a P value <0.002 indicating a significant relationship. The conclusion of this study is the inhalation of lavender aromatherapy (LavendulaAugustfolia) and neroli (Citrus Aurantium) can reduce the intensity of postpartum pain, but in the aromatherapy neroli inhalation group has a greater pain reduction score than the lavender group. 

scholarly journals Comparison between use of combination of mifepristone and misoprostol versus misoprostol alone in the management of intrauterine fetal death

2018 ◽  
Vol 7 (7) ◽  
pp. 2778
Author(s):  
Sreeveena Talasani ◽  
Pran Hitha Venkamolla ◽  
Kalpana Betha
Keyword(s):  
Side Effects ◽  
Fetal Death ◽  
Intrauterine Fetal Death ◽  
P Value ◽  
Ultrasound Scan ◽  
Efficacy And Safety ◽  
Medical Sciences ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Background: Intrauterine fetal death (IUFD) is estimated to occur in 1% of all pregnancies. The advent of prostaglandins has revolutionized the management of IUFD. There are limited studies using a combined regimen of mifepristone and misoprost for induction of labor in IUFD. Hence this study was undertaken to assess the efficacy and safety of combined regimen with misoprostol alone, in the management of IUFD.Methods: This hospital based prospective study included 60 pregnant women with IUFD admitted at Mediciti Institute of Medical Sciences, during the period January 2015 to July 2016. An ultrasound scan was performed to confirm IUFD and localize the placenta. Women were divided alternatively into 2 groups with 30 in each group (group 1- women received 200 mg mifepristone orally followed by misoprostol after 24 hours & in group 2, 100 µg misoprostol  every 6 hourly for a maximum of 4 doses between gestational age  24-26 weeks, 25-50 µg 4 hourly for a maximum of 6 doses beyond 26 weeks).Results: The mean induction to delivery interval was 10 hours in group 1 and 16.3 hours in group 2 (p value 0.007). Mean dose of misoprostol required in group 1 was 1.87 and 2.67 in group 2 (p value 0.008). With respect to side effects, the two groups did not differ significantly.Conclusions: The combined regimen was more effective than misoprostol for the induction of labour in IUFD, in terms of higher rate of successful delivery and shorter induction to delivery interval. 

scholarly journals Considering the hypothesis of the pathophysiology of cellulite in its treatment

2017 ◽  
Vol 9 (2) ◽  
Author(s):  
José Maria Pereira de Godoy ◽  
Ana Carolina Pereira de Godoy ◽  
Maria de Fatima Guerreiro Godoy
Keyword(s):  
Clinical Trial ◽  
Medical Records ◽  
Ethics Committee ◽  
Clinical Treatment ◽  
P Value ◽  
Lymph Drainage ◽  
The Mean ◽  
Cervical Stimulation ◽  
Alpha Error ◽  
Paired T Test

The aim of this study was to evaluate perimetric reductions in the clinical treatment of cellulite (aesthetics) using the Godoy method in a randomized retrospective clinical trial. The medical records of 150 patients treated for cellulite in the period from 2006 to 2011 in the Clinica Godoy were revisited. Treatment comprised manual and mechanical lymph drainage and cervical stimulation for one hour per day over 10 days. The paired t-test was used for statistical analysis, with an alpha error of 5% (P-value <0.05) being considered acceptable. This study was started after being approved by the Research Ethics Committee of the Medicine School in São José do Rio Preto (FAMERP - no. 395- 2010), Brazil and after being registered as a clinical trial. The mean reduction of the 150 patients was 3.81±2.76 g (P-value <0.0001; 95% confidence interval: 3.408-4.223). A significant reduction in size was seen with the clinical treatment of cellulite giving an improvement in the physical appearance. Pathophysiological mechanisms such as regional skin lymphostasis seem to be involved in the formation of cellulite.

scholarly journals A Study on Serum Electrolyte Imbalance in Type-2 Diabetes Mellitus - A Hospital-Based Study

2020 ◽  
Vol 7 (48) ◽  
pp. 2847-2851
Author(s):  
Sreenivasulu Uppara ◽  
Bhagyamma Sollapurappa Narayanaswamy ◽  
Rama Kishore Akula Venkata ◽  
Thanuja Ramanna ◽  
Shyam Prasad B.R
Keyword(s):  
Diabetes Mellitus ◽  
Serum Creatinine ◽  
Serum Sodium ◽  
P Value ◽  
Diabetic Patients ◽  
Healthy Controls ◽  
Serum Chloride ◽  
The Mean ◽  
Group 2 ◽  
Group 1

BACKGROUND The multi-organ disorder, diabetes mellitus (DM) continues to be one of the commonest and challenging health-related problems in the 20th century, prevalent in about 9.3 % of the world's population in 2019 and likely to affect 10.2 % by 2030. Diabetes mellitus is a group of chronic metabolic disorders of multiple aetiology, characterized by chronic hyperglycaemia due to derangement in carbohydrate, fat and protein metabolism. Electrolytes are crucial in maintaining various metabolic functions and play a pivotal role in maintaining a healthy state's body. Diabetic patients are more prone to and frequently develop a constellation of electrolyte disorders due to hyperglycaemia, polydipsia and polyuria. METHODS Our study comprised a total of 70 subjects in the age group of 35 - 60 years with age and sex-matched controls. They were grouped into two groups; the first group, group-1 (healthy controls) and the second group was group-2 (patients of diabetes mellitus on oral hypoglycaemic agents with poor control). 5 ml of fasting venous blood was collected in a plain vacutainer tube in the morning after a zerocalorie overnight 08 hours fast. Post collection, the blood sample was used as serum or plasma or whole blood to estimate plasma glucose, blood urea, serum creatinine, serum sodium, serum potassium, serum chloride by kit methods using an auto analyser. RESULTS Among the various parameters tested, the mean value of fasting plasma glucose, blood urea, serum creatinine, serum potassium, serum chloride were higher in group-2 (diabetic patients) compared to group-1 (healthy controls) with a p-value of < 0.0001. The value of the mean of serum sodium was lower in group-2 (diabetes mellitus) compared to group-1 (healthy controls) with a p-value of < 0.0001. CONCLUSIONS We conclude that electrolyte abnormalities are present in diabetic patients and maybe a root cause for associated morbidity or mortality. These disturbances are generally seen in decompensated Diabetes Mellitus patients, elderly individuals and in the presence of renal impairment. KEYWORDS Diabetes Mellitus, Serum Electrolytes, Fasting Blood Glucose

scholarly journals Correlation between Occurrence of Psychosomatic Disorders and Age during COVID-19 Lockdown

2021 ◽  
Author(s):  
Hetvi Bharatbhai Jethloja ◽  
Priyanka Birjubhai Unadkat ◽  
Radhika Kanaiyalal Raichura ◽  
Janvi Narendrasinh Rana ◽  
Nidhi Sudhir Ved
Keyword(s):  
Significant Positive Correlation ◽  
Pearson Correlation ◽  
P Value ◽  
Psychosomatic Disorders ◽  
Psychosomatic Disorder ◽  
Cross Sectional ◽  
Positive Correlation ◽  
Scale Scores ◽  
The Mean ◽  
Group 2

Introduction: The Coronavirus Disease-2019 (COVID-19) has caused a serious threat to people’s mental health causing psychosomatic disorders such as panic disorder, anxiety, and depression. Aim: To find out the correlation between the occurrence of psychosomatic disorders and age during the COVID-19 lockdown phase. Materials and Methods: This cross-sectional, observational study was conducted in Department of Physiotherapy at RK University, Rajkot, Gujarat, India. Males and females of age ≥21 years, with an ability to understand and fill Google form were recruited for the study. The subjects were divided into four groups according to age 21-34 years, 35-54 years, 55-64 years, and 65 years and older. There were 250 participants in each group. The subjects were asked to fill the COVID-19 Peritraumatic Distress Index (CPDI). Data were analysed by using software Statistical Package for the Social Science (SPSS) version 20. The normality of data was checked by the Shapiro Wilk test. Data followed parametric type so; Pearson correlation test was applied to find out the correlation between age and CPDI score. Results: The mean age of the population was 49.24±18.14 years. The mean CPDI scale scores were 27.572, 31.948, 31.364, and 35.328, respectively from groups 1 to 4. There was a significant positive correlation (p-value=0.031) in group 4, while no significance was found in group 1 (p-value=0.074), group 2 (p-value=0.067), and group 3 (p-value=0.062) Conclusion: There was a significant positive correlation between age and psychosomatic disorder occurrence in the geriatric age group (65 years and older) in the Rajkot city.

scholarly journals Effect of single low dose intrathecal labor analgesia on maternal and fetal outcome

2019 ◽  
Vol 8 (11) ◽  
pp. 4543
Author(s):  
Poonam Samyal ◽  
Rama Thakur ◽  
Rohini Rao ◽  
Gian Chauhan ◽  
Sharad Kaushik ◽  
...  
Keyword(s):  
Apgar Score ◽  
Low Dose ◽  
Labor Analgesia ◽  
Cervical Dilatation ◽  
P Value ◽  
Single Shot ◽  
Rescue Analgesia ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Background: Labour is one of the most painful experiences women encounter during their lifetime and the experience is different for each women. Aim of the study was to evaluate the effect of low dose intrathecal labour analgesia using fentanyl, bupivacaine and morphine on maternal and fetal outcome.Methods: 100 parturients with uncomplicated pregnancy in spontaneous or induced labor at cervical dilatation 4-6cm were enrolled for the study. They were randomized into two groups of 50 each, using computer based block randomization. Group 1 (N=50) received intrathecal labor analgesia using. Fentanyl (25µg), bupivacaine (2.5mg) and morphine (250µg) and Group 2 (N=50) received programmed labor. The two groups were well matched in terms of age, weight, height, parity, baseline vitals and mean cervical dilatation at the time of administration of labor analgesia . Progress of labor, duration of analgesia, and neonatal APGAR score were recorded. Feto-maternal and neonatal outcomes were studied and compared between the two groups.Results: The mean duration of analgesia in group1 was 238.96±21.888 min whereas the mean duration of analgesia in group 2 was 98.4±23.505 min. The difference was significant P value 0.00. One out of 50 (2%) of the parturients required rescue analgesia in Group 1. On the contrary all 44 parturients in Group 2 required rescue analgesia. Difference was significant (p value=0.00) However duration of the stages of labor, operative and instrumental deliveries and APGAR score did not differ in the two groups.Conclusions: Single shot intrathecal labor analgesia is a safe, effective, reliable, cheap and satisfactory method of pain relief for labor and delivery. Moreover, it is devoid of major side effects.

Efficacy of Transversus Abdominis Plane Block After Post Caesarean Section Delivery

2018 ◽  
Vol 16 (1) ◽  
pp. 2-6
Author(s):  
Grisuna Singh ◽  
Farhat Banu ◽  
Husneyera Haque
Keyword(s):  
Caesarean Section ◽  
Transversus Abdominis Plane Block ◽  
Transversus Abdominis ◽  
P Value ◽  
Transversus Abdominis Plane ◽  
Vas Score ◽  
Post Operative Pain ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Introduction: Post operative pain following caesarean section delivery can negatively affect early wound healing, proper breast feeding to the new born baby and therefore impair mother to child bonding. Combination of non steroidal anti inflammatory drugs (NSAIDS) and opioids has most commonly been used in pain management. The combination of regional anesthetic techniques like Transversus Abdominis Plane (TAP) block reduces pain and the dose of total analgesics consumed and therefore helps to prevent opioid related side effects. Objective: To evaluate the analgesic efficacy of Transversus Abdominis Plane block for management of postoperative pain in the first 24 hours after caesarean section. Methodology: It is a prospective randomized controlled single blinded study involving 60 patients of ASA II done in Nepalgunj Medical College Teaching Hospital over a period of 2 months. They are divided into two groups of 30 patients each. Group 1 received 20 ml of 0.25% isobaric bupivacaine in the triangle of Petit bilaterally. Group 2 received IV analgesics (NSAIDS and Tramadol 50 mg with Phenargan 25 mg). VAS score was taken every 6 hourly for 24 hours post operatively. Results: The mean VAS score of the patients in group 2 at 0-6 hours, 6-12 hours, 12-18 hours and 18-24 hours was 6.73(SD±0.69), 6.63(SD±0.610), 6.40(SD±0.56) and 6.43(SD±0.57) respectively. The mean VAS score of the patients who received block is significantly less as compared to those who did not receive the block with a p value of <0.001. The mean time to first analgesic request in group 1 was 10.83(SD±2.95) and in group 2 was 4.87(SD±0.68) with a p value of <0.001. In group 1, 70% patients received single dose of analgesics, 23.3% received two doses and 6.7% received three doses of analgesics. In group 2 all the patients received four doses of analgesics. Conclusion: Transversus Abdominis Plane Block can be used as a part of multimodal analgesic therapy for the management of post operative pain after caesarean section as it is technically less demanding, safe and economical. It reduces the side effects related with opioid analgesics and encourage early mobility, wound healing and proper mother to child bonding.

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