scholarly journals NEUTROPHIL TO LYMPHOCYTE RATIO, A NOVEL BEDSIDE PREDICTOR OF ENDOSCOPIC DAMAGE IN CORROSIVE GI INJURIES

2020 ◽  
pp. 1-3
Author(s):  
Noble Varghese Mathews ◽  
K. Premkumar ◽  
Murali Ramamoorthy ◽  
A. Chezhian ◽  
A. R. Venkateswaran ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
Caustic Ingestion ◽  
Severe Injuries ◽  
Cross Sectional ◽  
Lymphocyte Ratio ◽  
Medical College ◽  
Comparison Groups ◽  
History Of ◽  
Madras Medical College

AIM- To determine an association between neutrophil to lymphocyte ratio (NLR) and severity of endoscopic injury. MATERIALS AND METHODS- A cross-sectional study of 153 adult patients admitted to Madras medical college, following history of caustic ingestion during a 6-month period. The association between NLR within 24 hours of ingestion and endoscopic injury based on Zargar classification was studied. The association between NLR and endoscopic findings were studied. RESULTS AND DISCUSSION- Of the 153 patients studied, 117 had mucosal injuries and 36 normal. 54 of the 117 patients had multi-regional injury and 63 had single regional injuries. Of which, by Zargar classification, Grade I- 57, Grade II- 35 and Grade III-25 patients. Mean NLR of the sample was 3.4. AUC > 80% was noted for NLR cut-offs across all comparison groups namely, High vs lower grades (NLR≥4.32, AUC:0.978, 95% CI 0.95-1.0, p<0.001), a similar Turkish study by Uyar et al had a cut off of 8.7, however the sample size was smaller with only ten patients having poorer graded injuries. The NLR cut-offs of Injured vs non-injured (NLR≥1.49, AUC:0.845, 95% CI 0.78-0.91, p<0.001) and Single vs multi-regional injuries (NLR≥2.27, AUC:0.86, 95% CI 0.80-0.93, p<0.001), were comparable to the previous study. CONCLUSION- Higher NLR values predicted severe and multi-regional injuries. It helped to distinguish between mild and severe injuries, thereby serving as an inexpensive, non-invasive and bedside tool to predict and grade corrosive injuries for patients awaiting or inaccessible to immediate endoscopic evaluation and plan further care.

scholarly journals Association of Neutrophil to Lymphocyte Ratio with Clinicopathological Features in Breast Cancer

2021 ◽  
pp. 93-100
Author(s):  
Rufina Soomro ◽  
Namiya Cho
Keyword(s):  
Breast Cancer ◽  
Complete Blood Count ◽  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
Cross Sectional ◽  
Lymphocyte Ratio ◽  
Medical College ◽  
Breast Malignancy ◽  
Peripheral Blood Neutrophil ◽  
Inflammatory Conditions

Background: Even with the advances in the diagnosis and treatment of breast malignancy, to date breast cancer is still the number one cause of death in women in Pakistan. Various researches proved that prolonged inflammatory conditions played a part in progression of malignancy, these factors also promote growth leading to poor prognosis. This study shows the analysis of peripheral blood neutrophil to lymphocyte ratio (NLR) in breast malignancy and its association with disease characteristics Methods: The cross-sectional study was done in Liaquat National Hospital and Medical College, Karachi. Pakistan.  A total of 2059 female patient population with breast cancer hit the criteria. The patients were asked to undergo a complete blood count with leukocyte differential preoperatively. Patients’ complete data was collected preoperatively including specimen-related histopathology reports. Patients excluded were those with clinical evidence of ongoing active infection/sepsis, any blood disorders, any previous or ongoing inflammatory or autoimmune diseases, and steroid therapy. Results: No association was seen between the NLR with the age, grade, and luminal subtypes. However, NLR had a significant association with the size and stage of the disease. With an increase in NLR, the stage increased. Conclusion: The study identifies the usefulness of the NLR ratio, which in the future can be used as a diagnostic adjunct in the preoperative workup of patients with breast malignancy.

scholarly journals THE DEMOGRAPHIC PROFILE OF WOMEN WITH GESTATIONAL DIABETES MELLITUS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Priyanka Inaniya ◽  
B S Meena ◽  
Mohan Lal Meena ◽  
Aparna Sharma ◽  
Shalini Rathore
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Demographic Profile ◽  
Medical College ◽  
History Of ◽  
Socio Demographic Factors

Background: The present study aimed to study the demographic profile women with gestational diabetes mellitus Methods: This hospital based cross-sectional study Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur. Results: Mean age of patients was 27.68 ± 4.4 Yrs. Most of the study subjects in GDM group (54.7%) were Hindu. Study subjects in GDM group were almost equally from rural (50.7%).Most of the study subjects in both GDM group (88%) were housewives. Habit of smoking was found in only 6.7% females in GDM group. Habit of alcohol was found in 4% females in GDM group. Family history of diabetes was seen more in females with GDM (17.3%). Conclusion: This study concluded that the socio demographic factors influence the occurrence of GDM. Keywords: GDM, Age, Gravida

scholarly journals TO STUDY THE ONSET AND PROGRESSION OF AIRWAY ABNORMALITY IN TERMS OF ALTERATION IN PFT IN ASYMPTOMATIC SMOKERS.

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Significant Difference ◽  
History Of ◽  
Young Smokers ◽  
The Mean ◽  
Group Ii

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers

scholarly journals A Cross-Sectional Study of Neutrophil-to-Lymphocyte Ratio in Diagnosing Acute Appendicitis in Hospital Melaka

2019 ◽  
Vol 26 (6) ◽  
pp. 55-66
Author(s):  
Khairol Ashraf Ahmad ◽  
◽  
Noorharisman Ideris ◽  
Syed Hassan Syed Abd Aziz ◽  
◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lymphocyte Ratio

scholarly journals Associations between the Neutrophil-to-Lymphocyte Ratio and Diabetic Complications in Adults with Diabetes: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Heng Wan ◽  
Yuying Wang ◽  
Sijie Fang ◽  
Yi Chen ◽  
Wen Zhang ◽  
...  
Keyword(s):  
Diabetic Complications ◽  
Large Population ◽  
Cross Sectional Study ◽  
Cerebrovascular Diseases ◽  
Neutrophil To Lymphocyte Ratio ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Lymphocyte Ratio ◽  
Urine Albumin ◽  
Laboratory Index

Objective. The neutrophil-to-lymphocyte ratio (NLR) is an inexpensive and easily measurable laboratory index indicating systemic inflammation, while the application of many other inflammatory markers has been limited in daily clinical practice. However, large population studies about investigating the associations of the NLR level with diabetic complications including cardiovascular and cerebrovascular diseases (CVD), diabetic kidney disease (DKD), and diabetic retinopathy (DR) in the same population were limited. The aim of our study is to evaluate the associations between the NLR level and the prevalence of CVD, DKD, and DR in adults with diabetes simultaneously. Methods. A cross-sectional survey of 4,813 diabetic adults was conducted in seven communities in China. Persons underwent several medical examinations, including the measurement of anthropometric factors, blood pressure, routinely analyzed leukocyte characteristics, glucose, lipid profiles, urine albumin/creatinine ratio, and fundus photographs. Results. Compared with the first quartile of the NLR level, the odds of having CVD was significantly increased by 21% for participants in the highest quartile (OR 1.21; 95% CI 1.00, 1.47) (P for trend<0.05). Similarly, the prevalence of DKD among participants in the highest quartile of the NLR level was significantly increased by 150% (OR 2.50; 95% CI 1.95, 3.19) (P for trend<0.05). However, no association was found between the NLR level and the prevalence of DR (P for trend>0.05). These associations were all fully adjusted. Conclusions. A higher NLR level was associated with an increased prevalence of CVD and DKD, other than DR, in diabetic adults.

scholarly journals Comparison of KAtex, Bone Marrow Aspiration and DAT for the Diagnosis of Visceral Leishmaniasis

2019 ◽  
Vol 6 (1) ◽  
pp. 12-15
Author(s):  
Ishrat Sharmin ◽  
AKM Quamruzzaman ◽  
Rezina Parveen ◽  
M Abdulah Yusuf ◽  
Rashida Akter Khanam
Keyword(s):  
Bone Marrow ◽  
Visceral Leishmaniasis ◽  
Leishmania Donovani ◽  
Bone Marrow Aspiration ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Kala Azar ◽  
History Of ◽  
One Year

Background: Newly developed KAtex test can be used as a non invasive tool for diagnosis of Kala-azar. Objectives: The aim of the present study was to compare KAtex, Bone marrow aspiration and DAT to diagnose VL. Methodology: This cross-sectional study was carried out in the Department of Microbiology at Dhaka Medical College, Dhaka, Bangladesh in collaboration with the Department of Parasitology, Institute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh for a period of one year. Clinically suspected Kala-azar (VL) cases of different age and sex attending IEDCR, Dhaka from different Kala-azar endemic areas of Bangladesh were selected for this study. Patients having fever for more than 2 weeks, with or without splenomegaly, having history of loss of body weight following onset of fever were clinically suspected as Kala-azar cases. Microscopy and culture was performed in bone marrow (BM). KAtex was performed with urine sample. Agglutination of sensitized latex indicated presence of Leishmania donovani antigen in urine and thereby visceral leishmaniasis. No agglutination indicates absence of antigen in urine. DAT was done with serums of all cases. Result: Among 130 clinically suspected VL cases, 70 (53.85%) cases were BM positive and 60(46.15%) cases were BM negative. All the 70 BM positive cases were positive by KAtex and DAT. Among 60 BM negative cases, 15 were positive by KAtex and 23 were positive by DAT. The sensitivity of KAtex was 100.0% and specificity was 75.0%. The sensitivity of DAT was 100.0% and specificity is 61.6%. Conclusion: In conclusion, KAtex test is a good diagnostic tool for the detection of VL in comparison with DAT. Bangladesh Journal of Infectious Diseases, June 2019;6(1):12-15

scholarly journals FREQUENCY OF STROKE IN HYPERTENSIVE PATIENTS

2014 ◽  
Vol 21 (03) ◽  
pp. 484-488
Author(s):  
Ashok Kumar Lohano ◽  
Adnan Samie ◽  
Noor Nabi Siayal
Keyword(s):  
Risk Factors ◽  
Intracerebral Hemorrhage ◽  
Cross Sectional Study ◽  
Medical Department ◽  
Cross Sectional ◽  
Medical College ◽  
Long Duration ◽  
History Of ◽  
Study Setting ◽  
Improve Patient

Objective: To determine the frequency of intracerebral hemorrhage inhypertensive patients. Study design: Cross sectional study. Setting: This study was conductedat Medical department of Peoples Medical College & Hospital Nawabshah, from 01-01-2012 to31-12-2012. Material and methods: Admitted patient through emergency department withhistory of hypertension more than two years, meeting the inclusion criteria taken consent fromattendant. Patient was referred for C.T scan brain presence of hyperdense area was consideredas intracerebral hemorrhage. Inclusive criteria were age >20 years, either sex and patients withhistory of hypertension more than two year with any two or more sign and symptoms like suddenunconsciousness or with hemiplegia, hemiparesis, dysarthria. Aphasia, cranial nerve palsies.Exclusion criteria were age less than 20 years, normotensive patients with cerebral hemorrhageand patients with traumatic hemorrhage. Results: Among 281 patients that had stroke, therewere 147 males and 134 females with a sex ratio males: female 1:1. Mean age of patientsadmitted with intracerebral hemorrhage was 37.89 ± 7.33 years with an average age amongmales and females was same. Duration of hypertension was greater than 20-25 years in most ofthe patients nearly 63.7%. Patients with long duration of diabetes and hypertension presentedwith intracerebral hemorrhage. Nearly all the patients with intracerebral hemorrhage weresmokers 145, only 2 patients were non smokers and nearly all had long history of smoking. The127 patients who presented with intracerebral hemorrhage were obese. All risk factors werestatistically significant and were responsible for intracerebral hemorrhage. Conclusions:Hypertension is a risk factor for intra cerebral hemorrhage. An effort should be made to controlblood pressure and other modifiable risk factors to reduce incidence of intra cerebralhemorrhage and improve patient outcomes.

scholarly journals Study of prevalence and socio-demographic determinants of pterygium in Sub Himalayan region, India

2018 ◽  
Vol 6 (12) ◽  
pp. 3916
Author(s):  
Abhishek Padha ◽  
Prateek Koul ◽  
Swati Sharma
Keyword(s):  
Cross Sectional Study ◽  
Himalayan Region ◽  
Palpebral Fissure ◽  
Cross Sectional ◽  
Total Study Population ◽  
Medical College ◽  
Department Of Ophthalmology ◽  
History Of ◽  
Study Population ◽  
Grade Ii

Background: Pterygium, derived from the Greek work ‘pteryx’, meaning wing is a growth of fibrovascular tissue on the cornea and conjunctiva in the palpebral fissure. The present study was conducted to find out the prevalence and Socio-demographic determinants of pterygium in Sub Himalayan region of Himachal Pradesh, India.Methods: A cross-sectional study was conducted between the months of May-June 2018, in the outpatient department of Ophthalmology of Pt. Jawahar Lal Nehru Govt. Medical College and Hospital, Chamba, H.P, India. Among all the patients visiting the OPD in the given duration, a total of 200 patients having Pterygium were selected for the study. Detailed history of the all the patients were taken and required examination was done. Data collected was analysed with Microsoft excel software.Results: Out of the 200 patients, 59% were males and 41% were females. 70% of the total study population were seen in the age group 41-60years. In present study a total of 130 patients (65%) were outdoor workers. Left eye (40.5%) was the eye most frequently involved eye in present study, right eye (36.5%) also both the eyes were involved in 23% of study population. Nasal pterygium was seen in 93%, temporal pterygia 5.5% and double pterygium (both nasal and temporal presentation in same eye) in 1.5% patients. Grade I pterygium was seen in 43.5% patients, grade II in 40% and grade III pterygia were found in 16.5% of the study population.Conclusions: People living in high altitude regions and who work outdoors, are subjected to increased U.V. exposure. So, they must take appropriate precautions like wearing protective glasses and caps etc.

scholarly journals Body Mass Index and its Relation with Socio-Demographic Factors among Healthcare Workers

BioMedica ◽  
2021 ◽  
Vol 37 (2) ◽  
pp. 93-99
Author(s):  
Mehnaz Munir ◽  
Hamza Nadeem Malik ◽  
Muhammad Jareer Alam ◽  
Ammara Arif ◽  
Fiza Khalid
Keyword(s):  
Body Mass Index ◽  
Family History ◽  
Marital Status ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
History Of ◽  
Socio Demographic Factors ◽  
History Of Obesity

<p><strong>Background and Objective:</strong> Obesity leads to multiple complications that in turn increase mortality worldwide. There is a rapid rise in obesity in the last decade, especially among physicians. The objective of this study was to find out the frequency and relationship of obesity with socio-economic factors among faculty of a local medical college in Lahore, Pakistan.<br /><strong>Methods: </strong>A descriptive cross-sectional study was conducted on 162 medical and paramedical staff of Fatima Memorial College of Medicine and Dentistry, Lahore for a duration of 7 months from February 2019 to August 2019. Data were collected by filling the questionnaires and standard tools were used for height and weight measurement. Overweight/obesity was defined as a body mass index of &ge;25 kg/m2.<br /><strong>Results:</strong> In this study, out of 86 males and 76 females, the majority of the respondents were between the ages of 21 and 35 years. Seventy three (45.1%) and thirty (18.5%) respondents were overweight and obese, respectively. Out of a total 162 subjects, 38 (24%) were hypertensive and 18 (11%) were suffering from diabetes. There was a statistically significant association of obesity with age (p &lt; 0.05), marital status (p &lt; 0.001), family history of obesity (p &lt; 0.001), and smoking (p &lt; 0.05).<br /><strong>Conclusion: </strong>Risk factors like age, marital status, family history of obesity, and smoking have a strong correlation with obesity in faculty members of a medical school.</p>

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