Efficacy of Supratarsal Triamcinolone Injection versus Dexamethasone in Recalcitrant Vernal Keratoconjunctivitis

2021 ◽  
Vol 15 (10) ◽  
pp. 2590-2592
Author(s):  
Muhammad Amin ◽  
Abdul Bari Kakar ◽  
Chakar Tajwidi ◽  
Nesr Farooq ◽  
Hafiz Waqar Ahmad Ghauri ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Randomized Study ◽  
High Rate ◽  
Vernal Keratoconjunctivitis ◽  
Conjunctival Hyperemia ◽  
Medical College ◽  
Group I ◽  
Department Of Ophthalmology ◽  
Triamcinolone Injection ◽  
Group Ii

Aim: To determine the effectiveness of supratarsal triamcinolone injection versus dexamethasone in recalcitrant vernal keratoconjunctivitis. Study Design: Prospective/randomized study Place and Duration of Study: Department of Ophthalmology, Lorallai Medical College, Loralai from 1st October 2020 to 31st March 2021. Methods: Fifty patients (100 eyes) of both genders and age between 12-40 years were enrolled. Detailed demographics of enrolled cases age, sex and body mass index were recorded after taking informed written consent. All patients had recalcitrant vernal keratoconjunctivitis. Patients were equally divided into 2-groups. Group I had 25 patients and received 20mg of supratarsal triamcinolone injection in both eyes and group II with 25 patients received 2mg of dexamethasone in their eyes. Postoperative effectiveness, complications and recurrence of disease was observed and compared among both groups. Results: There were 15 (60%) males and 10 (40%) females in group I with mean age 18.14±6.34 years while in group II, 15 (60%) males and 10 (40%) females with mean age was 17.68±4.54 years. Palprebral vernal keratoconjunctivitis was found in 36 eyes (10 patients of group I and 8 patients of group II) and Mixed vernal keratoconjunctivitis in 64 eyes (15 patients of group I and 17 patients of group II). Symptoms were itching,photophobia, lacrimation and pain. Conjunctival hyperemia, giant papillae and limbal infiltrate were the most common signs observed. Post operatively effectiveness among group I and II was (100% vs 92%) without any complication. Recurrence rate of vernal keratoconjunctivitis in group I was lower 4% as compared to group II 10%. Conclusion: The use of supratarsal triamcinolone injection in patients of recalcitrant vernal keratoconjunctivitis was effective and safest method as compared to dexamethasone in terms of less recurrence and high rate of efficacy. Keywords: Supratarsal triamcinolone, Dexamethasone, Vernal keratoconjunctivitis, Effectiveness, Recurrence

scholarly journals TO STUDY THE ONSET AND PROGRESSION OF AIRWAY ABNORMALITY IN TERMS OF ALTERATION IN PFT IN ASYMPTOMATIC SMOKERS.

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Significant Difference ◽  
History Of ◽  
Young Smokers ◽  
The Mean ◽  
Group Ii

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers

scholarly journals Pulmonary Function Test of Forced Vital Capacity and Slow Vital Capacity Using Spirometry in Young Adults With Respect to Body Mass Index: A Normative Study

2020 ◽  
Vol 5 (8) ◽  
pp. 1094-1111
Author(s):  
Jyothy Anthraper ◽  
Dr. Reeny Roy
Keyword(s):  
Body Mass Index ◽  
Pulmonary Function ◽  
Body Mass ◽  
Lung Volume ◽  
Forced Vital Capacity ◽  
Vital Capacity ◽  
Management Tool ◽  
I 18 ◽  
Group I ◽  
Group Ii

Objectives: To determine the effect of Age, Gender and its correlation on pulmonary functions of Forced Vital Capacity and Slow Vital Capacity in Group I (18-24 years) and Group II (25-30 years) with respect to Body Mass Index.  Methodology: Sixty healthy adults between 18-30 years were included in the study. Participants were subdivided into Group I (18 to 24 years) and Group II (25 to 30 years) each group having 15 males and 15 females. The parameters considered were expiratory reserve volume, tidal volume, inspiratory capacity, forced vital capacity and slow vital capacity. Spirometer RMS HELIOS 401 was used. Procedures were explained to each participant; best values from 3 maneuvers were documented and were subjected to analysis.  Results: It is noticed a significant difference in various parameters of pulmonary function. As age increases there was an increase in body mass index and the lung volume also increased. Overall males had higher pulmonary function compared to females, males in Group II (25-30 years) was better compared to males in Group I (18-24 years). With an increase in body mass index, pulmonary function was increased in males compared to females. Age, gender, age, and gender interaction effect with respect to Body Mass Index was seen.  Conclusion: Values obtained can be used as reference standard for estimation of lung volume for age group 18-30 years. In future, Spirometry can be used as a clinical assessment and management tool in the field of speech language pathology, by modifying respiratory patterns to control lung volumes, phonations and the flow of speech.

scholarly journals Comparison between Clinical Efficacies of Levobupivacaine Plain and Levobupivacaine with Fentanyl for Urological Surgeries under Subarachnoid Block

2017 ◽  
Vol 2 (2) ◽  
pp. 34-39
Author(s):  
Aarti Kulkarni ◽  
Paulomi Dey
Keyword(s):  
Side Effects ◽  
Motor Block ◽  
Randomized Study ◽  
Categorical Variables ◽  
Transurethral Resection Of Prostate ◽  
Sensory Level ◽  
Hemodynamic Parameters ◽  
Subarachnoid Block ◽  
Group I ◽  
Group Ii

ABSTRACT Background and aims Spinal anesthesia for urological operations has been frequently used, because symptoms of overhydration, transurethral resection of prostate (TURP) syndrome, and bladder perforation can be recognized. This prospective randomized study was conducted to compare the clinical efficacies of levobupivacaine with and without fentanyl in subarachnoid block with respect to onset and duration of sensory and motor block and duration of analgesia in urological surgeries. Materials and methods This randomized study was conducted in 100 patients of American Society of Anesthesiologists (ASA) physical status grades I and II, posted for urological surgeries. Patients were randomly allocated to two groups and were given the following drugs intrathecally as per group distribution: Group I: 2.5 mL of 0.5% isobaric levobupivacaine and group II: 2.2 mL of 0.5% isobaric levobupivacaine with 15 μg (0.3 mL) fentanyl citrate. Parameters monitored were onset and duration of sensory and motor block, hemodynamic parameters, postoperative analgesia, and side effects. Data were analyzed using Student's t-test for the continuous variables and chi-square test for categorical variables. Results The onset of sensory level of T10 was earlier in group II (4.74 ± 0.723 minutes) than in group I (5.7 ± 0.953 minutes). Duration of sensory block was longer in group I (292.2 ± 8.154 minutes) than in group II (260 ± 11.066 minutes). Motor block regressed earlier in group II (181.2 ± 7.73 minutes) than in group I. Hemodynamic parameters and side effects were similar in both the groups. Conclusion From our study, we concluded that plain levobupivacaine provided a longer duration of sensory and motor subarachnoid blockade. However, addition of fentanyl as a spinal adjuvant had a dose-sparing effect with earlier onset and early regression of motor block and no hemodynamic alterations. How to cite this article Kulkarni A, Dey P. Comparison between Clinical Efficacies of Levobupivacaine Plain and Levobupivacaine with Fentanyl for Urological Surgeries under Subarachnoid Block. Res Inno in Anesth 2017;2(2):34-39.

scholarly journals Use of bacterial cellulose in closure of nasal septal perforation

2019 ◽  
Vol 5 (4) ◽  
pp. 830
Author(s):  
Yasser Mohammad Hassan Mandour ◽  
Mohammed Fahmy Shendy ◽  
Samer Badie ◽  
Ahmed Elrefai ◽  
Samira Mohammed ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Randomized Study ◽  
Inferior Turbinate ◽  
Septal Deviation ◽  
Surgical Correction ◽  
Septal Perforation ◽  
Nasal Septal Perforation ◽  
Group I ◽  
Group Ii ◽  
Better Than

<p class="abstract"><strong>Background:</strong> 30 patients with nasal septal perforation after surgical correction of septal deviation undergoing trials of septal closure were divided into 2 groups to compare between results of free inferior turbinate graft with bacterial cellulose and results of free inferior turbinate graft only in closure of nasal septal perforation. To compare between results of free inferior turbinate graft with bacterial cellulose and results of free inferior turbinate graft only in closure of nasal septal perforation.</p><p class="abstract"><strong>Methods:</strong> Prospective randomized study in which 30 patients with nasal septal perforation after surgical correction of septal deviation undergoing trials of septal closure were divided into 2 groups; group I (15 patients) in which free inferior turbinate graft with bacterial cellulose would be used in closure of nasal septal perforation; group II (15 patients) in which free inferior turbinate graft only would be used in closure of nasal septal perforation.  </p><p class="abstract"><strong>Results:</strong> Septal perforation healing (closure) would be in 10 patients in group I while in 6 patients in group II. Improvement in nasal obstruction, crustion, epistaxis and breathing sound in group I would be better than in group II.</p><p class="abstract"><strong>Conclusions:</strong> Use of free inferior turbinate graft with bacterial cellulose would be an effective method than use of free inferior turbinate graft only in closure of nasal septal perforation.</p>

scholarly journals Comparison of safety and number of post-operative visits of patients in convenient day versus conventional first day follow-up after phacoemulsification

2021 ◽  
Vol 37 (5) ◽  
Author(s):  
Zahid Kamal ◽  
Ahmad Zeeshan Jamil ◽  
Hira Shuja Khokhar ◽  
Farah Huma
Keyword(s):  
Visual Acuity ◽  
Intraocular Lens ◽  
Anterior Segment ◽  
Care Facility ◽  
Health Care Facility ◽  
Creative Commons ◽  
Group I ◽  
Department Of Ophthalmology ◽  
Group Ii

Objectives: To compare safety and number of post-operative visits of patients in convenient day versus conventional first day follow-up after phacoemulsification Methods: This observational cohort study was conducted in Department of ophthalmology, Sahiwal Medical College, Sahiwal from November 2019 to August 2020. There were 600 patients who underwent uncomplicated phacoemulsification with intraocular lens implantation. Patients were allocated into two groups. Group-I comprised of patients with convenient day follow-up during the first post-operative week. Group-II comprised of the patients with conventional first day follow-up. Rate of complications, number of visits during the first month and final visual acuity were recorded. Results: In Group-I post-operative complications were noted in 12.67% cases on first follow up visit and in 2.67% cases on first month follow up visit. In Group-II post-operative complication were noted in 22 % cases on first follow up visit and in 4% cases on first month follow up visit. Common postoperative complications were corneal oedema, anterior segment intraocular inflammation, residual lens matter in anterior chamber and intraocular lens subluxation. There was no difference in presenting and postoperative visual acuity between the two groups. Mean follow-up visits were 2.23 ± 0.42 in Group-I and 3.55 ± 0.50 in Group-II. Conclusion: Convenient day follow-up is as safe as conventional first day follow-up. Convenient day follow-up significantly reduces the number of post-operative visits. This would translate into cost reduction both for the patients and the health care facility. doi: https://doi.org/10.12669/pjms.37.5.4121 How to cite this:Kamal Z, Jamil AZ, Khokhar HS, Huma F. Comparison of safety and number of post-operative visits of patients in convenient day versus conventional first day follow-up after phacoemulsification. Pak J Med Sci. 2021;37(5):---------.  doi: https://doi.org/10.12669/pjms.37.5.4121 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals The functional state of the system of immunological protection in traumatic disease in patients with an increased body mass index

2019 ◽  
Keyword(s):  
Body Mass Index ◽  
Multivariate Analysis ◽  
Body Mass ◽  
Functional State ◽  
Adaptation Mechanism ◽  
Group Iii ◽  
Functional Relationships ◽  
Group I ◽  
Group Ii ◽  
Immunological Protection

Introduction. An important reserve that provides adaptation processes in the immunoregulation system is the possibility of its various subsystems to redistribute structural and functional relationships between them. The approach from the perspective of systemic multivariate analysis will allow us to determine the main functional relationships that arise or are violated at different periods of traumatic disease in patients with an increased body mass index (IBMI) during polytrauma in the immune response as a whole. Aim. The aim of this study was to analyze the functional state of the immunological protection system for traumatic disease in patients with IBMI. Materials and methods The integral indicators of immunogenesis were determined using a systematic multivariate analysis on the basis of a dynamic study of 1344 complex immunograms in 224 patients with IBMI with polytrauma and a different initial value of BMI. Patients were divided into 3 groups: group I - 88 patients with BMI of up to 29.9 (26.1 ± 3.1); group II - 84 patients with BMI of up to 30.0 - 39.9 (35.2 ± 3.8 ), group III - 52 patients with BMI > 40.0 (46.2 ± 5.8). The study was conducted on the 1st, 3rd, 7th, 14th, 30th and 360th days from the moment of receiving a polytrauma. Results. In the functional state of the immune system as a whole, certain regularities were identified in patients with IBMI with polytrauma: impairment of immunoreactive processes was prolonged for 1 year or more from the time of polytrauma, regardless of BMI, their nature is regular and unidirectional, have periods of decline and increase in activity; the degree of damage, the ability of compensatory possibilities and the ability to restore them depending on BMI, since the initial deviations of the integral indicator are almost identical in all groups of patients; the immune mechanisms at all times are most determined by the state of the cell link and complement system for patients of I and III groups. Moreover, the development mechanism of secondary post-traumatic immunodeficiency, which is associated with the inclusion of extended T-suppression and a decrease in IgA concentration for more than 14 days, depends on BMI; a clear cooperation of cellular and humoral relationships, which is aimed at compensating for its consequences, was determined in patients of group II as well as active participation in the immune reactions of HLA-DR + lymphocytes as a delicate adaptation mechanism. The development of functional instability of the system occurred mainly due to the T-cell link a year after the case of polytrauma. Conclusion. Our analysis made it possible to prove objectively on mathematical models that traumatic disease is a long process. Clinical and pathogenetic aspects of immune disorders are beyond question and provide the basis for the application of the proposed treatment algorithms and changes in stereotypes regarding the treatment approach as a whole.

scholarly journals Efficacy of Azoles Antifungals in Treatment of Pityriasis Versicolor

2022 ◽  
Vol 19 (1) ◽  
pp. 43-46
Author(s):  
Smita Jha
Keyword(s):  
Adverse Effects ◽  
Pityriasis Versicolor ◽  
Limited Disease ◽  
Oral Fluconazole ◽  
Medical College ◽  
Group I ◽  
Oral Itraconazole ◽  
Group Ii ◽  
200Mg Daily ◽  
Different Doses

Introduction: Pityriasis versicolor is superficial fungal infection. Topical drugs are often effective in treatment of limited disease while systemic drugs are more suitable in extensive cases. The systemic triazole drugs, itraconazole and fluconazole have shown promising results at different doses. Aims: To assess the efficacy and safety of oral fluconazole combined with ketoconazole shampoo and oral itraconazole in the treatment of Pityriasis versicolor. Methods: The study was conducted at department of Dermatology at Nepalgunj Medical College from March 2019 to February 2020. Total 100 patients of both genders with Pityriasis versicolor were randomly allocated into two groups with 50 patients in each group. Patients in Group I received oral fluconazole 300mg a week for two consecutive weeks along with ketoconazole 2% shampoo twice weekly for two weeks while those in Group II received  itraconazole 200mg daily for one week. Efficacy was assessed in terms of negative fungal hyphae. The drug is considered safe if no patients were withdrawn for clinical adverse effects or laboratory abnormalities. Results: In this study age ranged from 18 to 50 years with mean age of 31.1 years in Group I and 31.92 years in Group II. Efficacy was seen in 78% of Group I patients as compared to 54% in Group II patients at two weeks and 94% in Group I and 90% in Group II at four weeks. No significant adverse effects were reported in any of the group. Conclusion: Fluconazole along with ketoconazole shampoo is more effective than itraconazole in treatment of pityriasis versicolor with minimal side effects, at lesser cost.

scholarly journals Evaluation of outcome of early appendectomy in appendicular lump

2020 ◽  
Vol 8 (1) ◽  
pp. 7
Author(s):  
A. S. M. Rezbanul Haque ◽  
Bablu Kumar Saha ◽  
M. Mahfuzul Haque ◽  
M. Abdus Sattar ◽  
Upendra Nath Ray ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Recovery Period ◽  
Medical College ◽  
Group I ◽  
Perforated Appendix ◽  
Early Exploration ◽  
The Mean ◽  
Group Ii ◽  
Surgery Department ◽  
The Cost

Background: Appendicular lump is a well-known sequalae of acute appendicitis encountered in 2-6% of patients. Successful management of appendicular lump is controversial with different approaches. This study aims to evaluate the outcome of early appendectomy in an appendicular lump.Methods: A total of 210 patients were admitted in surgery and pediatric surgery department of Rangpur medical college and hospital with the diagnosis of acute appendicitis and its sequalae over two years.Results: In this study, sixty patients were included who were presented with an appendicular lump. Maximum patients (50%) were found in the age group of 21-30 years. Males (66.67%) were more affected. Eighty percent of patients were coming from below-average socio-economic conditions. In group I, early appendicectomy had done and outcomes were satisfactory and favorable. In group II, eighteen patients were operated who were admitted at 6 to 8 days after an attack of acute appendicitis, and twelve patients were continued the conservative treatment. In group II, who had done surgery, among them, fourteen patients (77.78%) were found an appendicular abscess, and four patients (22.22%) were found perforated appendix per-operatively. In group I, the mean recovery period was less and they had minimum complications. In group II, the mean recovery period was more and they had more complications.Conclusions: Based on these findings, it can be concluded that early exploration in appendicular lump patients confirm the diagnosis, cures the problem, reduces the cost of management, and shortens the convalescence period and hospital stay with reasonably satisfactory outcomes.

scholarly journals Comparison Intra Articular Steroid vs. Hydraulic Distention for the Treatment of Frozen Shoulder

2013 ◽  
Vol 1 (1) ◽  
pp. 3-9 ◽  
Author(s):  
GP Singh
Keyword(s):  
Pain Relief ◽  
Teaching Hospital ◽  
Frozen Shoulder ◽  
College Teaching ◽  
Muscle Relaxants ◽  
Medical College ◽  
Group I ◽  
Normal Sleep ◽  
Group Ii

Background Frozen shoulder is a chronic fibrosing condition of the capsule of the shoulder joint. OBJECTIVE The objective of the study was to compare the result of treatment of frozen shoulder by Hydraulic Distention under local anesthesia with steroid and intra articular steroid alone. Sample Size: 60 patients were taken in this study and were divided into two groups. Duration and Setting: The study was conducted in 2005-2006 treated in the department of orthopaedic, Janaki medical college Teaching Hospital, Janakpur. Materials and Methods: It was a prospective, observational, comparative and clinical study. Sixty patients were selected from Dhanusha District of Janakpur, Nepal. They were divided into two groups. Since January 2005 to January 2006 periods in the department of orthopedics surgery, Janaki Medical College & Teaching Hospital, Janakpur. The Group I was treated by hydraulic distention of glenohumeral joint with 50ml normal saline with steroid, oral medicines (analgesics and muscle relaxants) and exercises. Patients in group II were treated by intra-articular steroid followed by oral medicines (analgesics and muscle relaxants) and exercises. Results: The average age of patients in group I was 52 ± 2.16 years and 50 ± 2.03 in group II. There were 37 (63%) females and 23 (37%) males in our study. Female to male ratio was 1.7:1. All patients in group noted immediate pain relief with excellent return of range of motion (ROM) and resumption of normal sleep. At the end of 45 days of follow up all patients had returned to their normal daily activities. Most of them got excellent ROM and pain relief. All patients in group II noted immediate pain relief and resumption of almost normal sleep. At the end of 45 days of follow up most of the patient presented with good relief of pain but could not return to most of their normal activities because of less improvement in ROM. Conclusions: Hydraulic distension technique is quick, safe and gives early results, so it should be considered first for the treatment of frozen shoulder. DOI: http://dx.doi.org/10.3126/jucms.v1i1.8415   Journal of Universal College of Medical Sciences Vol.1(1) 2013: 3-9

scholarly journals A comparative study in between tropical honey and povidone dressing in diabetic wounds in a medical college of Northern India

2018 ◽  
Vol 5 (10) ◽  
pp. 3391
Author(s):  
Akhilesh Kumar Yadav ◽  
Sankalp Dwivedi ◽  
Siddharth Desai
Keyword(s):  
Hospital Stay ◽  
Diabetic Foot ◽  
Povidone Iodine ◽  
Subsequent Treatment ◽  
Medical College ◽  
Northern India ◽  
Group I ◽  
Stay Time ◽  
Group Ii ◽  
Age Range

Background: The study was done to compare outcomes with dressings of honey to povidone iodine in the management of diabetic foot ulcers.Methods: The present study was carried out for a period of three years from June 2016 to July 2018 in a medical college of northern India. About 200 patients who presented with features of diabetic foot were selected randomly and included in this study and divided into two groups based upon the subsequent treatment of raw area with honey and povidone- iodine respectively.Results: A total of 200 patients were studied. Group I consist of 100 patients out of which 58 were males and 42 females while in Group II there were 56 males and 44 females. The age range in group I was 46 to 75 years while the age range in group II was 48 to 82 years.  In case of group I time of healing was 7- 75 days with median of 28 while in group II time of healing was 7- 60 days with median of 18 days. In case of group II time of healing was 7-60 days with median of 18 days, hospital stay was 7- 34 days with median of 12 days.Conclusions: In terms of hospital stay, time of healing, allergy to material and need for amputation honey was found to be better than povidone iodine solution for dressing of diabetic foot ulcers.

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