The Distribution of Aerobic and Anaerobic Bacteria in the Etiology of Granulomatous Mastitis and Their Resistance to Antimicrobial Agents

ABSTRACT Resistance of Gram-positive pathogens to first-line antimicrobial agents has been increasing in many parts of the world. We compared the in vitro activities of torezolid with those of other antimicrobial agents, including linezolid, against clinical isolates of major aerobic and anaerobic bacteria. Torezolid had an MIC90 of ≤0.5 μg/ml for the Gram-positive bacterial isolates tested and was more potent than either linezolid or vancomycin.

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Bacteroides Fragilis: Current Susceptibilities, Mechanisms of Drug Resistance, and Principles of Antimicrobial Therapy

Drug Intelligence & Clinical Pharmacy ◽

10.1177/106002808602000712 ◽

1986 ◽

Vol 20 (7-8) ◽

pp. 567-573 ◽

Cited By ~ 5

Author(s):

George J. Cuchural ◽

Francis P. Tally

Keyword(s):

Nutritional Support ◽

Antimicrobial Agents ◽

Susceptibility Testing ◽

Anaerobic Bacteria ◽

Bacteroides Fragilis ◽

High Rate ◽

Beta Lactam ◽

Beta Lactam Antibiotics ◽

Bacteroides Fragilis Group ◽

Aerobic And Anaerobic

The Bacteroides fragilis group of organisms includes the most clinically important anaerobic bacteria. Optimal therapy of infections in which these organisms are involved includes adequate and timely surgical drainage of all collections, debridement of necrotic tissue, optimal nutritional support, and administration of appropriate empiric antibiotics to cover both the aerobic and anaerobic bacterial components of these mixed infections. Special attention must be paid to the B. fragilis group because of its high rate of resistance to many of the commonly used antibiotics. Of the currently available beta-lactam antibiotics, piperacillin has the lowest rate of resistance. Successful antimicrobial agents include clindamycin, chloramphenicol, and metronidazole plus an aminoglycoside. Piperacillin, cefoxitin, and moxalactam can be used with an aminoglycoside or alone if no resistant organisms are revealed on culture and susceptibility testing. Beta-lactam-based regimens are potentially less toxic and may be less costly than those that contain one or more non-beta-lactam antibiotics.

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ComparativeIn VitroActivities of LFF571 against Clostridium difficile and 630 Other Intestinal Strains of Aerobic and Anaerobic Bacteria

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.06305-11 ◽

2012 ◽

Vol 56 (5) ◽

pp. 2493-2503 ◽

Cited By ~ 41

Author(s):

Diane M. Citron ◽

Kerin L. Tyrrell ◽

C. Vreni Merriam ◽

Ellie J. C. Goldstein

Keyword(s):

Clostridium Difficile ◽

Antimicrobial Agents ◽

Anaerobic Bacteria ◽

Elongation Factor ◽

Gram Positive ◽

Content Type ◽

Variable Activity ◽

Intestinal Origin ◽

Aerobic And Anaerobic

ABSTRACTThein vitroactivities of LFF571, a novel analog of GE2270A that inhibits bacterial growth by binding with high affinity for protein synthesis elongation factor Tu, fidaxomicin, and 10 other antimicrobial agents were determined against 50 strains ofClostridium difficileand 630 other anaerobic and aerobic organisms of intestinal origin. LFF571 possesses potent activity againstC. difficileand most other Gram-positive anaerobes (MIC90, ≤0.25 μg/ml), with the exception of bifidobacteria and lactobacilli. The MIC90s for aerobes, including enterococci,Staphylococcus aureus(as well as methicillin-resistantS. aureus[MRSA] isolates),Streptococcus pyogenes, and other streptococci were 0.06, 0.125, 2, and 8 μg/ml, respectively. Comparatively, fidaxomicin showed variable activity against Gram-positive organisms: MIC90s againstC. difficile,Clostridium perfringens, andBifidobacteriumspp. were 0.5, ≤0.015, and 0.125 μg/ml, respectively, but >32 μg/ml againstClostridium ramosumandClostridium innocuum. MIC90forS. pyogenesand other streptococci was 16 and >32 μg/ml, respectively. LFF571 and fidaxomicin were generally less active against Gram-negative anaerobes.

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Aerobic and Anaerobic Bacteria in the Middle ear and ear Canal in Acute Otitis Media

Acta Oto-Laryngologica ◽

10.3109/00016488209108484 ◽

1982 ◽

Vol 93 (sup386) ◽

pp. 100-102 ◽

Cited By ~ 3

Author(s):

J. Luotonen ◽

A. M. M. Jokipii ◽

P. Sipilä ◽

J. Väyrynen ◽

L. Jokipii ◽

...

Keyword(s):

Otitis Media ◽

Middle Ear ◽

Anaerobic Bacteria ◽

Acute Otitis Media ◽

Ear Canal ◽

Aerobic And Anaerobic

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Decontamination of the Oral Cavity. Effect of Six Local Anti-Microbial Preparations in Comparison to Water and Parafilm as Controls

Journal of International Medical Research ◽

10.1177/030006058801600204 ◽

1988 ◽

Vol 16 (2) ◽

pp. 98-106 ◽

Cited By ~ 4

Author(s):

C. Matula ◽

M. Hildebrandt ◽

G. Nahler

Keyword(s):

Hydrogen Peroxide ◽

Oral Cavity ◽

Anaerobic Bacteria ◽

Crossover Design ◽

Double Blind ◽

Bacterial Counts ◽

Aerobic And Anaerobic ◽

Cavity Effect ◽

Bacterial Effect ◽

Observation Period

Six preparations (four liquid and two solid) were tested in a double-blind crossover design for their anti-bacterial effect on aerobic and anaerobic bacteria in saliva of 12 volunteers. The four liquid preparations contained either tyrothricin, hexetidine, hydrogen peroxide or ethanol and were tested against a rinse with water as control. The two solid preparations, in the form of lozenges, contained tyrothricin in doses of 4 or 10 mg and were tested against parafilm. A single rinse with either tyrothricin or hexetidine resulted in a significant reduction of aerobic and anaerobic bacteria in saliva which lasted for the whole 1h observation period and was considerably more effective than hydrogen peroxide or ethanol. Similar results were seen with the solid preparations. The lozenge containing 10 mg tyrothricin was the most effective and was the only formulation capable of reducing oral aerobic bacterial counts by a factor of approximately 100.

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In vitro antimicrobial susceptibility of anaerobic bacteria isolated from caprine footrot

Acta Veterinaria Hungarica ◽

10.1556/avet.55.2007.1.2 ◽

2007 ◽

Vol 55 (1) ◽

pp. 11-20 ◽

Cited By ~ 2

Author(s):

Angela Lacombe-Antoneli ◽

S. Píriz ◽

S. Vadillo

Keyword(s):

Antibiotic Treatment ◽

Antimicrobial Susceptibility ◽

Antimicrobial Agents ◽

Anaerobic Bacteria ◽

Gram Negative ◽

Western Spain ◽

Clinical Cases

The in vitro antimicrobial susceptibility of Gram-negative anaerobic bacilli commonly isolated from footrot in goats was studied. A total of 97 isolates belonging to the genera Dichelobacter, Fusobacterium, Prevotella, Porphyromonas and Bacteroides, obtained from clinical cases of footrot in south-western Spain between March 2000 and May 2001, were tested against 25 antimicrobial agents comprising β-lactams, aminoglycosides, macrolides, chloramphenicol, quinolones, lincosamides, sulphonamides and tetracyclines in order to optimise antibiotic treatment of this disease in goats. β-lactams, tetracyclines and metronidazole displayed the highest in vitro efficacy against the species involved in the pathogenesis of footrot.

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In Vitro and In Vivo Antibacterial Activities of a Novel Glycylcycline, the 9-t-Butylglycylamido Derivative of Minocycline (GAR-936)

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.43.4.738 ◽

1999 ◽

Vol 43 (4) ◽

pp. 738-744 ◽

Cited By ~ 283

Author(s):

P. J. Petersen ◽

N. V. Jacobus ◽

W. J. Weiss ◽

P. E. Sum ◽

R. T. Testa

Keyword(s):

Anaerobic Bacteria ◽

Tetracycline Resistance ◽

Protective Effects ◽

Gram Negative ◽

E Coli ◽

Resistance Determinants ◽

Aerobic And Anaerobic ◽

Ribosomal Protection

ABSTRACT The 9-t-butylglycylamido derivative of minocycline (TBG-MINO) is a recently synthesized member of a novel group of antibiotics, the glycylcyclines. This new derivative, like the first glycylcyclines, theN,N-dimethylglycylamido derivative of minocycline and 6-demethyl-6-deoxytetracycline, possesses activity against bacterial isolates containing the two major determinants responsible for tetracycline resistance: ribosomal protection and active efflux. The in vitro activities of TBG-MINO and the comparative agents were evaluated against strains with characterized tetracycline resistance as well as a spectrum of recent clinical aerobic and anaerobic gram-positive and gram-negative bacteria. TBG-MINO, with an MIC range of 0.25 to 0.5 μg/ml, showed good activity against strains expressing tet(M) (ribosomal protection), tet(A), tet(B),tet(C), tet(D), and tet(K) (efflux resistance determinants). TBG-MINO exhibited similar activity against methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant streptococci, and vancomycin-resistant enterococci (MICs at which 90% of strains are inhibited, ≤0.5 μg/ml). TBG-MINO exhibited activity against a wide diversity of gram-negative aerobic and anaerobic bacteria, most of which were less susceptible to tetracycline and minocycline. The in vivo protective effects of TBG-MINO were examined against acute lethal infections in mice caused by Escherichia coli, S. aureus, andStreptococcus pneumoniae isolates. TBG-MINO, administered intravenously, demonstrated efficacy against infections caused byS. aureus including MRSA strains and strains containingtet(K) or tet(M) resistance determinants (median effective doses [ED50s], 0.79 to 2.3 mg/kg of body weight). TBG-MINO demonstrated efficacy against infections caused by tetracycline-sensitive E. coli strains as well asE. coli strains containing either tet(M) or the efflux determinant tet(A), tet(B), ortet(C) (ED50s, 1.5 to 3.5 mg/kg). Overall, TBG-MINO shows antibacterial activity against a wide spectrum of gram-positive and gram-negative aerobic and anaerobic bacteria including strains resistant to other chemotherapeutic agents. The in vivo protective effects, especially against infections caused by resistant bacteria, corresponded with the in vitro activity of TBG-MINO.

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Bacteriological Findings within Internal Implant Hole Following Flapless Implant Placement

Journal of Baghdad College of Dentistry ◽

10.26477/jbcd.v30i3.2525 ◽

2018 ◽

Vol 30 (3) ◽

pp. 13-16

Author(s):

Khudair A Abd ◽

Basima G Ali ◽

Abbas S AL-Mizraqchi

Keyword(s):

Health Status ◽

Anaerobic Bacteria ◽

Bacterial Count ◽

Oral Health Status ◽

Viable Count ◽

Screw Hole ◽

Implant Placement ◽

Significant Difference ◽

Edentulous Patients ◽

Aerobic And Anaerobic

Back ground: Microbial penetration inside the implant's internal hole creates a bacterial reservoir that is related with an area of inflamed connective tissue opposite the fixture-abutment junction and this can affect the health of the peri-implant tissue. Aims of the study: Evaluate the types aerobic and anaerobic bacterial count-percentage and difference between Aerobic and Anaerobic microflora in the implant screw hole three months after implant placement. Monitor the periodontal health status of all patients, throughout the study. Material and methods: Study methodology; Eight partially edentulous patients received 20 dental implants and these implants done with flapless surgical procedure. All patients examined clinically to determined their oral health status by examination of their plaque index, Gingival index and Bleeding on probing, each two weeks for 90 days (8visits) throughout the study period. Three months after that, the plaque sample collected from the internal hole of fixture and transfer to bacterial investigation and assessment the amount of anaerobic and aerobic bacteria. Results: Although the anaerobic viable count is higher than that of aerobic, but with statistically not significant difference between those counts (P>0.05). Keywords: screw hole, flapless surgical implant placement, bacterial count, Aerobic and Anaerobic bacteria

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Microbiological, histological, technological, and toxicological preliminary study of dog's canned food

Journal of the Hellenic Veterinary Medical Society ◽

10.12681/jhvms.15756 ◽

2018 ◽

Vol 49 (2) ◽

pp. 110

Author(s):

S. RANTOS (Σ. ΡΑΝΤΟΣ) ◽

L. PANTOULAS (Λ. ΠΑΝΤΟΥΛΑΣ) ◽

I. SARAKATSIANOS (Ι. ΣΑΡΑΚΑΤΣΙΑΝΟΣ) ◽

G. ROZOS (Γ. ΡΟΖΟΣ) ◽

N. PAPAIOANNOU (Ν. ΠAΠΑΪΩΑNNOΥ)

Keyword(s):

Connective Tissue ◽

Water Activity ◽

Anaerobic Bacteria ◽

Full Agreement ◽

Canned Food ◽

Lead And Cadmium ◽

Preliminary Study ◽

Soya Proteins ◽

Aerobic And Anaerobic

During this study canned food for dogs of six firms were investigated (42 samples totally). Microbiologically the following parameters were checked: the commercial sterility, the water activity (aw), the pH, the presence of aerobic and anaerobic bacteria after incubation of tins in 25 ° C for 28 days, 32 ° C for 21 days and 55 ' C for 8 days. Histologically, the existence of different kinds of tissues was examined. Technologically Weende's analysis and separation of the tin's content were made. Toxicologically, the concentration of lead and cadmium were countered. The results showed that dog's canned food, in Greece, are supersterillised. Muscular, adipose and connective tissue are used for their production as well as byproducts and soya proteins by some firms. The results of Weende's analysis are in full agreement with the amount of nutriments that they were written on tins' labels.

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