TECHNICAL AND ECONOMIC EVALUATION OF THE DEVELOPMENT OF A DEVICE FOR THE PREVENTION OF APNEA DURING PHYSIOLOGICAL SLEEP IN HUMANS

2020 ◽  
pp. 198-210
Author(s):  
Сергей Борисович Казаков ◽  
Дмитрий Михайлович Шишов ◽  
Антон Игоревич Ларин ◽  
Александр Петрович Николаев ◽  
Аза Валерьевна Писарева
Keyword(s):  
Sleep Apnea ◽  
Humidity Sensor ◽  
Lung Ventilation ◽  
High Price ◽  
Device Structure ◽  
Artificial Lung Ventilation ◽  
Exact Moment ◽  
The Cost ◽  
Technical Solutions ◽  
Physiological Sleep

В статье представлен обзор существующих технических решений в сфере мониторинга и предотвращения апноэ во сне. Произведён анализ существующих аппаратов для предотвращения апноэ, который показал, что на рынке присутствует большое количество импортных моделей, однако они имеют довольно высокую цену. Разработанный нами Российский аналог проектируемого аппарата, при схожих характеристиках, будет иметь более привлекательную цену, чем у импортных приборов. Интегрирование датчика влажности в персональную маску пациента даёт возможность отслеживать остановки дыхания пациента во время сна, и тем самым включать процесс принудительной подачи дыхательной смеси именно в тот момент, когда она необходима для устранения патологии. Целью научной работы является разработка конструкции прибора и создание алгоритма программы для управления аппарата искусственной вентиляции лёгких для предотвращения апноэ во сне. Показана разработка структуры устройства аппарата. Подобран компрессор и датчик влажности с обоснованными характеристиками для создания аппарата, а также основные элементы. Разработана конструкция корпуса аппарата и разработана компоновка. Выполнено технико-экономическое обоснование разработки аппаратно-программного комплекса для предотвращения апноэ во сне. Показано, что себестоимость готового изделия достаточно конкурентна The article presents an overview of existing technical solutions in the field of monitoring and prevention of sleep apnea. An analysis of existing devices for preventing apnea was made, which showed that there are a large number of imported models on the market, but they have a fairly high price. The Russian analog of the designed device developed by us, with similar characteristics, will have a more attractive price than that of imported devices. The integration of the humidity sensor into the patient's personal mask makes it possible to monitor the patient's breathing stops during sleep, and thus enable the process of forced delivery of the respiratory mixture at the exact moment when it is necessary to eliminate the pathology. The purpose of the research is to develop the device design and create a program algorithm for controlling the artificial lung ventilation device to prevent sleep apnea. The development of the device structure is shown. The compressor and humidity sensor with reasonable characteristics for creating the device, as well as the main elements are selected. The design of the device body and its layout were developed. A feasibility study for the development of a hardware and software system for preventing sleep apnea has been completed. It is shown that the cost of the finished product is quite competitive

Progressive Early Rehabilitation Program Applied to Patients with Acute Cerebrovascular Accident

2020 ◽  
Vol 25 (3) ◽  
pp. 17-25 ◽  
Author(s):  
G. R. Ramazanov ◽  
L. B. Zavaliy ◽  
L. L. Semenov ◽  
S. A. Abudeev ◽  
A. O. Ptitsyn ◽  
...  
Keyword(s):  
Cerebrovascular Accident ◽  
Lung Ventilation ◽  
Rehabilitation Program ◽  
Artificial Lung ◽  
Early Rehabilitation ◽  
Gravity Gradient ◽  
Acute Cerebrovascular Accident ◽  
Artificial Lung Ventilation ◽  
Bed Days ◽  
Severity Of The Disease

Abstract. Early rehabilitation (ER) of patients with acute cerebrovascular accident (ACA) is one of the priority tasks of the vascular centers; the issue of increasing the volume of rehabilitation measures in the resuscitation and intensive care units (ICU) is relevant. Objective. To evaluate the safety and effectiveness of the progressive ER program in patients with ACA. Material and research methods. The study included 129 patients with ACA in ICU. Each patient of the main group (MGr, n = 61) underwent progressive ER: at least 4–5 vertical adjustments per day, passive mode Kinesiotherapy 49 ± 9.3 minutes, a double load of physiotherapy exercises, preventive physiotherapy; the total time of classes reached 240 minutes per day. In the comparison group (СGr, n = 68), standard ER was performed no more than 120 minutes per day. The groups are comparable by sex, age, severity of the disease and comorbidity. The severity of ACA, the gravity gradient, patient mobility, functional status, degree of dependence, and the presence of complications were evaluated. Results. During a month of work with the MGr, 102 ICU bed-days, 94 days of the artificial lung ventilation use, p < 0.05 were saved. Mortality in MGr decreased -— 8 patients (13.1%) versus 14 (20.6%) in CGr (p < 0.05). In patients within CGr, pulmonary thromboembolism developed in 8.8%, in MGr – in 3.3%. The severity of the apoplectic attack decreased ( by 28% in MGr, and by 20% in CGr ), mobility increased. Comparing the modalities of post resuscitationsyndrome in MGr, it was noted that the score decreased by 2 times from 6 [5; 6] to 3 [2.3; 3.3], but it has not changed in the CGr. Patients in the MGr were 2-–3 days earlier adapted to the vertical adjustment. Conclusions. The progressive ER program in ICU is safe, effective, realisable, and allows reducing the number of bed-days in ICU, the number of days of the artificial lung ventilation use, complications, and mortality in comparison with standard medical care.

Microcontroller Device for Conductor Identification Using Acoustic Signal

2020 ◽  
Vol 67 (1) ◽  
pp. 28-34
Author(s):  
Aleksandr V. Vinogradov ◽  
Aleksey V. Bukreev
Keyword(s):  
Acoustic Signal ◽  
Acoustic Waves ◽  
Theoretical Calculations ◽  
Poor Quality ◽  
Electrical Circuit ◽  
Research Purpose ◽  
Electrical Wiring ◽  
The Right ◽  
The Cost ◽  
Technical Solutions

When repairing and replacing electrical wiring in enterprises, the main difficulty is the lack or poor quality of documentation, plans for conductors laying. Distinguishing wires (cables) and their cores by the color of the shells or using tags attached to the ends is difficult if the shells have the same color and there are no tags. Devices and technical solutions used to identify wires and cables do not allow recognizing conductors without breaking the electrical circuit, removing insulation, and de-energizing the network. Searching for the right conductor is a time-consuming operation. (Research purpose) The research purpose is developing a new microcontroller device for identifying wires using an acoustic signal. (Materials and methods) Literature sources has been searched for devices for conductors identifying. (Results and discussion) The article proposes a method that involves feeding an acoustic signal to a wire at one point and capturing it at another, in order to recognize the desired wire. The article presents results of comparison of the developed microcontroller device for identifying conductors using an acoustic signal with known devices and methods for conductors recognizing. (Conclusions) The article reveals the shortcomings of existing methods and means of identifying wires and cables. Authors performed a theoretical calculation of the sound pressure in the conductor at a given distance. The article presents the calculation of speed of acoustic waves in conductors with different types of insulation. Authors designed a microcontroller device for identifying conductors using an acoustic signal and tested it. It was determined that the device increases the safety of work, reduces the cost of operating internal wiring and identification time; eliminates the violation of wire insulation, the need to disable electrical receivers. The convergence of theoretical calculations and experimental data was shown.

scholarly journals A METHODOLOGY TO SUPPORT COMPANIES IN THE FIRST STEPS TOWARDS DE-MANUFACTURING

2021 ◽  
Vol 1 ◽  
pp. 131-140
Author(s):  
Federica Cappelletti ◽  
Marta Rossi ◽  
Michele Germani ◽  
Mohammad Shadman Hanif
Keyword(s):  
Environmental Impact ◽  
End Of Life ◽  
Design Stage ◽  
Life Strategies ◽  
Disassembly Sequence ◽  
The Status ◽  
The Cost ◽  
Technical Solutions ◽  
First Time ◽  
Complex Activities

AbstractDe-manufacturing and re-manufacturing are fundamental technical solutions to efficiently recover value from post-use products. Disassembly in one of the most complex activities in de-manufacturing because i) the more manual it is the higher is its cost, ii) disassembly times are variable due to uncertainty of conditions of products reaching their EoL, and iii) because it is necessary to know which components to disassemble to balance the cost of disassembly. The paper proposes a methodology that finds ways of applications: it can be applied at the design stage to detect space for product design improvements, and it also represents a baseline from organizations approaching de-manufacturing for the first time. The methodology consists of four main steps, in which firstly targets components are identified, according to their environmental impact; secondly their disassembly sequence is qualitatively evaluated, and successively it is quantitatively determined via disassembly times, predicting also the status of the component at their End of Life. The aim of the methodology is reached at the fourth phase when alternative, eco-friendlier End of Life strategies are proposed, verified, and chosen.

scholarly journals Validity and Cost-Effectiveness of Pediatric Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children: Rationale, Study Design, and Methodology

2021 ◽  
Vol 4 (1) ◽  
pp. 9
Author(s):  
Esther Oceja ◽  
Paula Rodríguez ◽  
María Jurado ◽  
Maria Luz Alonso ◽  
Genoveva del Río ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Cost Effectiveness ◽  
Sleep Apnea ◽  
Therapeutic Interventions ◽  
Diagnostic Process ◽  
Urine Biomarkers ◽  
Obstructive Sleep ◽  
Respiratory Polygraphy ◽  
The Cost ◽  
The Impact

Obstructive sleep apnea (OSA) in children is a prevalent, albeit largely undiagnosed disease associated with a large spectrum of morbidities. Overnight in-lab polysomnography remains the gold standard diagnostic approach, but is time-consuming, inconvenient, and expensive, and not readily available in many places. Simplified Home Respiratory Polygraphy (HRP) approaches have been proposed to reduce costs and facilitate the diagnostic process. However, evidence supporting the validity of HRP is still scarce, hampering its implementation in routine clinical use. The objectives were: Primary; to establish the diagnostic and therapeutic decision validity of a simplified HRP approach compared to PSG among children at risk of OSA. Secondary: (a) Analyze the cost-effectiveness of the HRP versus in-lab PSG in evaluation and treatment of pediatric OSA; (b) Evaluate the impact of therapeutic interventions based on HRP versus PSG findings six months after treatment using sleep and health parameters and quality of life instruments; (c) Discovery and validity of the urine biomarkers to establish the diagnosis of OSA and changes after treatment.

scholarly journals Model Predictive Control Strategies to Activate the Energy Flexibility for Zones with Hydronic Radiant Systems

Energies ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 1195
Author(s):  
Ali Saberi Derakhtenjani ◽  
Andreas K. Athienitis
Keyword(s):  
Control Strategies ◽  
High Price ◽  
Electricity Prices ◽  
Peak Demand ◽  
Heating Systems ◽  
Electrical Grid ◽  
Demand Reduction ◽  
The Cost ◽  
Floor System ◽  
Radiant Floor Heating

This paper presents control strategies to activate energy flexibility for zones with radiant heating systems in response to changes in electricity prices. The focus is on zones with radiant floor heating systems for which the hydronic pipes are located deep in the concrete and, therefore, there is a significant thermal lag. A perimeter zone test-room equipped with a hydronic radiant floor system in an environmental chamber is used as a case study. A low order thermal network model for the perimeter zone, validated with experimental measurements, is utilized to study various control strategies in response to changes in the electrical grid price signal, including short term (nearly reactive) changes of the order of 10–15 min notice. An index is utilized to quantify the building energy flexibility with the focus on peak demand reduction for specific periods of time when the electricity prices are higher than usual. It is shown that the developed control strategies can aid greatly in enhancing the zone energy flexibility and minimizing the cost of electricity and up to 100% reduction in peak power demand and energy consumption is attained during the high-price and peak-demand periods, while maintaining acceptable comfort conditions.

MECHANICAL VENTILATION OF THE LUNGS WITH A TARGETED TIDAL VOLUME IN NEWBORNS AND INFANTS WITH VARIOUS LUNG DISEASES

2021 ◽  
Vol 100 (5) ◽  
pp. 76-82
Author(s):  
A.V. Mostovoy ◽  
◽  
S.S. Mezhinsky ◽  
A.L. Karpova ◽  
A.N. Nikolishin ◽  
...  
Keyword(s):  
Tidal Volume ◽  
Lung Diseases ◽  
Lung Ventilation ◽  
First Year ◽  
Lung Pathology ◽  
Pathological Conditions ◽  
Artificial Lung Ventilation ◽  
First Year Of Life ◽  
Ventilation Of The Lungs ◽  
Selection Of

The review presents and systematizes the current provisions on artificial lung ventilation (ALV) with a guaranteed or target tidal volume as the most effective and safe mode of ALV in neonatal practice. The application of this method of respiratory support is described. The authors present the main provisions on the optimal selection of the target tidal volume in various pathological conditions. The use of various modes of ALV in combination with a guaranteed tidal volume makes it possible to prevent or reduce the harmful impact of ALV in patients with acute and chronic lung pathology, in newborns and children in the first year of life.

scholarly journals The increased use value of bamboo leaves as silica source for t-type zeolite synthesis

2018 ◽  
Vol 197 ◽  
pp. 05003 ◽  
Author(s):  
Soni Setiadji ◽  
Citra Deliana Dewi Sundari ◽  
Endang Lala ◽  
Denia Febby Nurbaeti ◽  
Ira Novianti ◽  
...  
Keyword(s):  
Sem Analysis ◽  
High Price ◽  
Heating Process ◽  
Zeolite Synthesis ◽  
X Ray Diffraction ◽  
Cost Performance ◽  
Silica Source ◽  
Bamboo Leaves ◽  
Type Zeolite ◽  
The Cost

T-type zeolite can be used as catalyst, adsorbent, and membranes for gas separation. The synthesis of T-type zeolite needs to be optimized in both of the method and source of precursor, because of its relatively high price. In this research, the synthesis is done using silica extracted from bamboo leaves instead of commercial silica. This increases the value of the bamboo leaves and the cost-performance of zeolite synthesis. The silica was extracted from bamboo leaves ash using alkaline solvent. The extracted silica has 81.76% of purity and an amorphous phase. The T-type zeolite was synthesized using the molar composition of 0.15 Na2O : 0.025 Al : 0.15 K2O : 1 SiO2 : 15 H2O : 0.06 TMAOH, under hydrothermal method and heating process for 4 days, 60°C for 2 days and 120°C for the next 2 days. The characterization method using X-Ray Diffraction and Infra-Red Spectroscopy were performed to confirm the formation of T-type zeolite. The results of Scanning Electron Microscope (SEM) analysis show that the formed T-type zeolite has erionite cylindrical crystal shape.

scholarly journals Features of the functioning of the Ukrainian market for design work and the development of design in a pandemic.

2021 ◽  
Vol 2 (47) ◽  
pp. 11-24
Author(s):  
L.V. Shumak
Keyword(s):  
Construction Industry ◽  
Added Value ◽  
High Price ◽  
Highly Qualified ◽  
Design Work ◽  
Industrial Enterprises ◽  
Positioning Strategy ◽  
Economic Characteristic ◽  
High Level ◽  
The Cost

The market for design work in civil and industrial construction was one of the first to react to the crisis trends during a pandemic in the economy. Back in 2013, the volume of orders declined, and the peak of the decline was in 2014. The main reason for the difficulties is the reduction in investment programs of civil and industrial enterprises, and developers. The Ukrainian market for design works is distinguished by a high level of competition. A large number of design companies are actively working in this market niche. This fact constantly pushes market participants to take active steps to adjust the competitive strategy, positioning strategy and pricing. The primary signs of a crisis in design are also recognized through price indicators, which personify both the cost of the project or design services, and the results of the project enterprise, taking into account the factors that form the price level. In recent years, the price indicators of the construction industry have been unstable and completely dependent on external market conditions. Price as an economic characteristic is a significant regulator in the project market of Ukraine and abroad. The design market is the backbone of the construction industry with a volume of over UAH 1 billion per year and high added value. The field requires highly qualified staffing and the introduction of modern technologies. Outdated systems of training, certification of specialists and technical regulation hinder the development of the project market in Ukraine. The market is prone to underestimated cost of design work. In 2018, the share of design in the total cost of construction in Ukraine averaged 1.5-2%; in France it was 8-13%, and in Great Britain the level reached 10-17%. There is practically no system of state orders for design. Today our market is characterized by technological backwardness. The work of designers is low-paid, which, accordingly, affects the quality. High-quality architecture is more expensive than low-quality one. In Ukraine, the demand for quality design is just beginning to emerge. In this regard, it is very important to create a competitive environment that will contribute to development. The project market, like the construction industry as a whole, is extremely heterogeneous. Currently, there are thousands of various design bureaus and small workshops in Ukraine, employing no more than ten people, and the number of freelance designers cannot be statistically estimated. Prices for design, as well as the approaches used to provide services, differ dramatically in these organizations. A high price for a service does not necessarily guarantee that the quality of its delivery will be the same. Therefore, first of all, one should imagine what kind of work will be performed and what their essence is. Many investors prefer to design their facilities using the services of European specialists. What are the features and secrets of the Ukrainian project market? Are there really so few good designers in their country, and by what parameters can they still be found? The article examines the features of the functioning of the Ukrainian market for design work and the development of design in a pandemic.

Cleaning in Crystalline Si Solar Cell Manufacturing

2012 ◽  
Vol 195 ◽  
pp. 283-288 ◽  
Author(s):  
Juergen Schweckendiek ◽  
Ronald Hoyer ◽  
Sebastian Patzig-Klein ◽  
Franck Delahaye ◽  
Gerry Knoch ◽  
...  
Keyword(s):  
Solar Cell ◽  
Large Scale ◽  
Diffusion Coating ◽  
Production Lines ◽  
Si Solar Cell ◽  
The Subject ◽  
Similarities And Differences ◽  
The Cost ◽  
Technical Solutions ◽  
Near Future

The large scale of production of modern PV manufacturing as well as the cost pressure demand a different approach to cleaning processes in semiconductor and PV applications. The subject of this presentation is, to highlight aspects of similarities and differences. Total added cost/m2of Si are estimated for typical PV manufacturing conditions and compared to semiconductor applications. Typical technical solutions are reviewed. They are compared to the anticipated technical and cost requirements in the near future according to PV roadmaps and cell concepts which are evident today. Starting with typical cleaning processes during the wafering (sawing, cleaning, separation) up to cell processing (texturing, diffusion, coating and plating) the main cleaning processes are presented and their specifics are indicated. Finally recontamination and conditioning in production lines are reviewed.

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