scholarly journals Effect of Supraperiosteal Injection of Dexamethasone on Interappointment Pain in Teeth with Symptomatic Irreversible Pulpitis: A Comparative Study

2020 ◽  
Vol 1 (4) ◽  
pp. 4
Author(s):  
Lt Col Ajmal Yousaf ◽  
Fatima Ali ◽  
Syed Muzammil Hussain ◽  
Faisal Bhangar ◽  
Nasrin Yousaf ◽  
...  

Objective: To compare the effect of supraperiosteal injection of dexamethasone with 2% lidocaine on the frequency of interappointment endodontic pain at different time intervals. Study Design: Prospectivecomparativestudy. Place and Duration of Study: The study was carried out at operative department of Armed Forces Institute of Dentistry, Rawalpindi from 1st October 2019 to 31st March 2020. Materials and Methods: A total of 100 patients presenting to the Department of Operative Dentistry, Armed Forces Institute of Dentistry, Rawalpindi and giving consent for participation, aged 20-50 years from both genders, presenting with acutely inflamed pulp in their maxillary first molars were selected for this study using convenient sampling technique. The patients were randomly divided into two equal groups of 50 patients with the help of scientific random number table. Endodontic therapy was initiated, pulpectomy canals were prepared with ProTaper Next system, intra-canal dressings of calcium hydroxide were placed and the cavity was restored with Cavit till the next appointment. Group A patients were then injected with dexamethasone at the mucobuccal fold and group B patients were injected with lidocaine used as placebo. Pain was recorded at 48 and 72 hours using the visual analogue scale. Data was analyzed using SPSS 21. Results: The study included equal number of male and females. The mean age of group A was 35 ± 4.5 years while of group B was 33 ± 6.7 years. The results showed that dexamethasone does not reduce pain at 48 and 72 hours compared to the placebo. Conclusion: It is concluded that dexamethasone does not reduce interappointment endodontic pain when compared to a placebo.

2016 ◽  
Vol 5 (2) ◽  
pp. 32-36
Author(s):  
Azam Mahmood ◽  
Saad Saleem ◽  
Muhammad Usman Khan

OBJECTIVE To compare the effects of trigger point (TrP) pressure release with ultrasound therapy to reduce rhomboid pain due to TrP. STUDY DESIGN Experimental study STUDY SETTINGS Outpatient department of Ziauddin Hospital, Clifton campus, Karachi, Pakistan. SAMPLE SIZE 50 patients SAMPLING TECHNIQUE Simple random sampling. The patients were divided into two groups of 25. Group A were given TrP pressure release treatment with exercise and group B were given ultrasound (u/s) treatment with exercise. OUTCOME MEASURES The outcome measures were visual analog scale (VAS) for pain and functional rating index (FRI) for functional performance RESULTS In group A, mean pain score on VAS before the treatment were 5.88±1.130 and after treatment were 1.80±1.041 with a p-value of <0.006. Group B, mean pain score on VAS before treatment were 6.56±1.446, after treatment were 2.72±1.208, with a p-value of <0.006. The mean FRI in group A before treatment was 39.92 ± 2.691 and after treatment was 29.60 ± 5.454, with a p-value of 0.002. The mean FRI in Group B before treatment was 41.12 ± 2.505 and after treatment was 35.92 ± 4.183, with a p-value of 0.002.


2016 ◽  
Vol 20 (2) ◽  
pp. 50-59
Author(s):  
Dureja Gaurav ◽  
Singh Gagandeep

Purpose: The present study was designed to measure superstitious behavior among Judo, Taekwondo and Boxing players. Material: Thirty (N=30) male inter-college level players with the age group of 19-25 years were selected through purposive sampling technique to act as subjects from affiliated colleges of Panjab University, Chandigarh. They were further divided into three groups: Group-A [Judo (n=10)], Group-B [Taekwondo (n=10)] and Group-C [Boxing (n=10)]. One Way Analysis of Variance (ANOVA) was applied to find out the differences among judo, taekwondo and boxing players. Where F values found significant, Least Significant Differences (LSD) Post-hoc test was applied to find out the direction and degree of difference. Results: The level of significance was set at 0.05. The result revealed significant differences among judo, taekwondo and boxing players on the sub parameters: clothing and appearance, preparation, team ritual and coach. However, no significant differences have been observed on the sub-parameters fetish, game/competition, prayer and parameter superstitious (Total). Conclusions: The obtained results showed significant differences on the sub-parameter Coach among Judo, Taekwondo and Boxing players. While calculating the mean values of entire groups, it has been observed that Boxing players demonstrate significantly better on the sub-parameter Coach. Therefore, it can be ascertained that Boxing players are more confident that coach bring a lucky charm to our game.


Author(s):  
Haramritpal Kaur ◽  
Jatin Gupta ◽  
Amandeep Singh ◽  
Gurpreet Singh ◽  
Anshul Dahuja ◽  
...  

Background: Endotracheal intubation is associated with hemodynamic stress responses. Various drugs have been used in the past to attenuate the pressor response; however, none has been proved to be ideal. Present study was planned to evaluate the oral pregabalin 150 mg and clonidine 200 µg for attenuation of pressor response to intubation.Methods: The study was conducted on 100 adult patients of either gender scheduled to undergo elective surgeries under general anaesthesia (GA). The patients were randomly allocated into 2 groups. In group A patients received pregabalin 150mg and in group B patients received clonidine 200µg orally. The hemodynamic parameters were recorded until 10 minutes after intubation. The sedation, anxiety and side effects were also assessed.Results: In clonidine group, the mean HR remained below the baseline value at all the time intervals. In pregabalin group, the mean HR remained below the baseline value at most of the time intervals but increased above baseline just after intubation (T0i) and 1 minute after intubation (T1i) where increase was only 1.488±1.20% and 0.45±1.16% respectively from baseline. In both pregabalin and clonidine groups, the mean SBP and MAP remained below the baseline value (Tb) at all the time intervals from T0.5 to T10i. Both clonidine and pregabalin provided adequate anxiolysis and sedation with pregabalin providing more pronounced sedation and anxiolysis than clonidine.Conclusions: Both clonidine and pregabalin are effective oral premedication drugs for attenuation of the pressor response to laryngoscopy and endotracheal intubation.  


2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Shan Chen ◽  
Yu-Tong Jin ◽  
Zheng-Yang Zhu ◽  
Ling-Tao Wu ◽  
Ping Yang ◽  
...  

Objective. To investigate the site of action of sinapine thiocyanate (ST), following acupoint herbal patching (AHP). Methods. Twenty Wistar rats were randomized into five groups (groups A, B, C, D, and E), and all groups received the same AHP in vivo. Skin samples were excised at 2 h, 4 h, 6 h, 10 h, and 26 h after AHP administration from group A to group E separately and the concentrations of ST in the skin were determined using a liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) method. A pharmacokinetic profile of ST following AHP was performed at the same time in a group of five Wistar rats to detect plasma levels at the same time intervals. Results. The mean ± SD ST concentrations (ng/ml) at 2 h (group A), 4 h (group B), 6 h (group C), 10 h (group D), and 26 h (group E) after AHP administration were 250.01±61.99, 61.01±30.41, 40.12±26.94, 78.66±59.43, and 19.55±18.95, respectively. No ST was detected in rats’ plasma samples at the same time points. Conclusions. The site of action of ST following AHP is in the skin.


2019 ◽  
Vol 26 (08) ◽  
pp. 1359-1364
Author(s):  
Sara Jamil ◽  
Rizwan Jouhar ◽  
Dinaz Gandhi ◽  
Tayyaba Tahira ◽  
Jamshed Shaikh

Endodontic Pain if occurs after few hours or days after the treatment indicates a poor pathosis and a bad prognosis in long term, due to this a newer generation of instruments for canal treatment has been introduced from Ni-Ti alloy which has even better ability to shape narrow and curved root canals, without causing aberration. To compare the mean postoperative pain score after manual SS (stainless steel) K-files and mechanical Ni-Ti rotary path files in patients with irreversible pulpitis. Study Design: Randomized controlled trial. Setting: Department of Operative Dentistry, Altamash Institute of Dental Medicine, Karachi. Period: 6 months from 01-10-2017 to 30-03-2018. Materials and Methods: Total 60 patients of irreversible pulpitis with moderate pain score ≥5 were included and divided equally in manual stainless-steel k-files and mechanical Ni-Ti rotary path files groups. Treatment was started with local anesthesia. Patients were recalled after 24 hours and the level of postoperative pain was examined. T-test was applied to compare the outcome in both groups. Stratification was done using t-test and P value ≤0.05 was significantly considered. Results: The mean pre-treatment VAS in group-A and group-B was 7.16±1.44 and 7.86±1.38 respectively. Mean post-treatment VAS in group-A and group-B was 2.33±1.02 and 1.10±0.66 respectively. A significant difference between the pre and post op pain was noted between the two groups, when compared after 24hours by using VAS. Conclusion: Mean post-operative pain score was significantly less with NiTi rotary path files as compare to manual stainless steel K-files.


2021 ◽  
Vol 71 (6) ◽  
pp. 2184-88
Author(s):  
Ajmal Yousaf ◽  
Fatima Ali ◽  
Afshan Bibi ◽  
Ahsan Masood Ahmed ◽  
Sana Ashfaq ◽  
...  

Objective: To find the effect of different combinations of Calcium Hydroxide for the management of post-operative pain in acute apical periodontitis. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Operative Dentistry Armed Forces Institute of Dentistry, Rawalpindi. from Jun to Nov 2019. Methodology: A total of 282 patients presenting with acute apical periodontitis in their mandibular posterior teeth were selected for this study and were randomly divided into three equal groups with the help of scientific random number table. Group-A patients were given intracanal dressing of Calcium Hydroxide mixed with Chlorhexidine, group-B patients were given intracanal dressing of Calcium Hydroxide mixed with Saline and group-C patients were given intracanal dressing of Calcium Hydroxide mixed with Dexamethasone. Endodontic therapy was initiated after application of rubber dam, following pulpectomy and disinfection with frequent irrigation, canals were prepared and intra-canal dressings were placed according to the allotted group and the cavity was restored till the next appointment. Post-operative pain was recorded at 24 hours, 48 hours and one week using the visual analogue scale. Results: The three intra-canal combinations of Calcium Hydroxide used in the study were found to be equally effective in reducing pain. Overall, the result between the three groups after 24 hours proved to be insignificant (p=0.40), after 48 hours (p=0.84) and 1 week (p=0.45) were also insignificant. Conclusion: Calcium Hydroxide mixed with Saline, Chlorhexidine and Dexamethasone are all effective for pain reduction with dexamethasone being the most effective.


2016 ◽  
Vol 6 (3) ◽  
pp. 148-151
Author(s):  
AQM Ataul Haque ◽  
Mohsin Khalil ◽  
Seheli Zannat Sultana ◽  
Dider Hossain Chowdhury ◽  
Fakrul Amin Mohammad Hasanul Banna

Background: The neuronal organisation of the cerebellum has been studied in details by many researchers. But most of these have been performed on animals and diameter of superior cerebellar peduncle in humans remains inadequately studied. It has been observed by various workers that dimensions of different organs in Bangladeshi population vary from those of Western population.Objective: Aim of the present work was to measure diameter of superior cerebellar peduncle to make a standard for Bangladeshi population.Materials and Methods: This observational study was done by using nonprobability sampling technique and performed by examining 63 cerebellum. Out of them 40 postmortem human cerebellums were collected from Bangladeshi cadavers of both sexes (male 25 and female 15) aged 5 to 60 years and 23 cerebellums from caesarian section of intrauterine death cases of both sexes (male 14 and female 9) aged 34 to 41 weeks of gestation. Specimens were collected from dead bodies autopsied on different dates from April to September 2009 at the autopsy laboratory of Department of Forensic Medicine and prenatal cases from Gynaecology and Obstetrics Department of Mymensingh Medical College & Hospital, Mymensingh. The collected specimens were grouped into three age groups - Group A (28 to 42 weeks of gestation), Group B (5 to 30 years) and Group C (31 to 60 years). The diameters of the superior cerebellar peduncles of both cerebellar hemispheres were measured by using slide calipers and expressed in millimeter (mm). The measurement was taken after fixation into 10% formol saline.Results: The mean (± SD) diameters of right superior cerebellar peduncle in Group A was 4.96 ± lAO, in Group B 6.83 ± 1046 and in Group C was 6.61 ± 1.34 mm. The mean (± SD) diameters of left superior cerebellar peduncle in GroupA was 4.87 ± 1.25, in Group B 6.79 ± 1045 and in Group C 6048 ± 1.37 mm.Conclusion: No significant difference was observed between mean diameters ofright and left superior cerebellar peduncles.J Enam Med Col 2016; 6(3): 148-151


2021 ◽  
Vol 17 (1) ◽  
pp. 229-239
Author(s):  
Vijayapriyangha Senthilkumar ◽  

Root canal therapy linked to pulpal diseases or trauma is common in modern dental care. The 2% Lidocaine which is considered as the gold standard has some drawbacks in pulpal anaesthesia. Ropivacaine has beneficial anaesthetic effects on pulpal anaesthesia. Therefore, it is of interest to compare and evaluate the pulpal aesthetic effect using 0.5% Ropivacaine and 2% Lidocaine in symptomatic irreversible pulpitis. A double blinded randomized controlled clinical trial consisting of 110 lower molar and premolar tooth with irreversible pulpitis cases for root canal therapy were selected and randomly divided into 2 groups. Group A: 2% lidocaine with epinephrine and Group B: 0.5% ropivacaine. The pulp sensibility tests with heat test, cold test and electric pulp test were completed. The preoperative pain score was measured with Visual Analogue Scale (VAS) pain scale. Classical inferior alveolar nerve block (IANB) technique was given to all patients by a single operator. Subjects were asked for lip numbness and presence or absence of lip numbness. Postoperative pain scores were recorded during access opening and on placing files in the canal. There is no statistical difference between the groups during pre operative conditions. The mean pain scores within group A and group B is recorded. The difference was found to be statistically significant with p value ≤ 0.05. Significant difference between the mean values after and before the treatment is observed. However, there is no statistical significance between the mean pain scores between the access and pulp. The 0.5% Ropivacaine and 2% Lidocaine with epinephrine does not have any significant difference during access opening. However, 0.5% Ropivacaine groups were effective while placing the file in the canal. Thus, 0.5% Ropivacaine showed better results even though it was not statistically significant for further consideration in this context.


2017 ◽  
Vol 24 (08) ◽  
pp. 1181-1184
Author(s):  
Mehr Imran ◽  
Muhammad Umair Fiaz ◽  
Muhammad Arslan ◽  
Ayesha Khalid

Objectives: To compare the efficacy of duloxetine with amitriptyline for reductionin the frequency of pain management in patients with diabetic neuropathy. Study Design: It isa Comparative, Randomized and Prospective study. Setting: Medical Unit-4, DHQ, Hospital,Faisalabad. Study Duration: 5 months, October, 2016 to February 2017. Methods: A total of100 cases (100 in each group) between the age 20-65 years of any gender, ≥ 5years historyof diabetes, symptoms of peripheral neuropathy for at least six months, having HbA1c >7.5%were included while those with co-existing other causes of peripheral neuropathy (porphyria,chronic renal failure, amyloidosis, leprosy, hypothyroidism), pregnant and lactating womenand use of Duloxetine or amitriptyline in previous three months were excluded from the study.Randomization was done by computer generated random number table, to allocate patientsto either group A (Duloxetine group) or group B (Amitriptyline group). Patients were instructedto take study medication in the morning, with a glass of water for up to 6 weeks. Group A wasgiven 60mg Duloxetine each day and Group B was given 75mg amitriptyline in a single dose.Baseline pain was recorded on VAS. Diary card was provided to all patients at the baseline visit.Each morning during the 1st 3 weeks, patients would be instructed to record the severity of thesymptoms in term of reduction in pain score recorded by visual analogue scale. After 3 weeks,an additional three weeks supply of medication was dispensed and patients were scheduled toreturn at week 6 for the final evaluation that was recorded by me in terms of reduction in painscore and also assessed for 50% reduction in pain score from base line that was labeled asreduced. Patients were followed up by keeping telephonic contacts of patients. Results: In ourstudy, out of 200 cases (100 in each group) 21%(n=21) in Group-A and 17%(n=17) in Group-Bwere between 20-40 years of age while 79%(n=79) in Group-A and 83%(n=83) in Group-Bwere between 41-65 years of age, mean+SD was calculated as 47.08+11.43 and 48.37+10.83respectively, 56%(n=56) in Group-A and 49%(n=49) in Group-B were male while 44%(n=44)in Group-a and 51%(n=51) in Group-B were females, comparison of efficacy in both groupswas done which shows that 62%(n=62) in Group-A and 35%(n=35) in Group-B were treatedeffectively, which shows a significant difference between the two groups. Conclusion: It isconcluded that the efficacy of duloxetine as compared to the amitriptyline in terms of reductionin frequency of pain in the management of patients of diabetic neuropathy is significantly higher.


2015 ◽  
Vol 22 (08) ◽  
pp. 1071-1075
Author(s):  
Farhan Ahmed ◽  
Ali Hasan ◽  
Noormah Mehmood

Objective: To compare mean duration of stay (in hours) of patients with newimprovised versus conventional methods of phototherapy among neonates with jaundice.Study Design: Randomized control trial. Period: Six months. Setting: Neonatal ward,Department of Paediatric Medicine, Lahore General Hospital, Lahore. Subjects and Methods:160 patients, with the help of random number table, all the patients were randomly dividedinto 2 groups A and B, after getting the informed consent from their parents. Group A patientsreceived conventional phototherapy. Group B patients received phototherapy with reflectingmirrors placed beneath and at the side of the patient in baby’s cot (new improvised methodof phototherapy). Results: In this study the mean age of patients in group-A and group-Bwas 2.70±1.13 days and 2.12±1.98 days respectively. In group-A there were 47 (58.75%)male and 33 (41.25%) female patients while in group-B there were 51 (63.75%) male and 29(36.25%) female patients. According to hospital stay, the mean hospital stay in group A was39.76±11.80 hours and in group-B it was 44.90±14.21 hours, the mean hospital stay wasstatistically significant (p<0.001) Conclusion: Shorter mean duration of stay (in hours) wasrecorded in patients treated with new improvised as compared to conventional methods ofphototherapy among neonates with jaundice, the data is primary in our country, this techniquemay be used further but after some more trials to confirm its efficacy regarding shorter durationof hospital stay


Sign in / Sign up

Export Citation Format

Share Document