scholarly journals Face Numbers and Nongeneric Initial Ideals

10.37236/1882 ◽  
2006 ◽  
Vol 11 (2) ◽  
Author(s):  
Eric Babson ◽  
Isabella Novik

Certain necessary conditions on the face numbers and Betti numbers of simplicial complexes endowed with a proper action of a prime order cyclic group are established. A notion of colored algebraic shifting is defined and its properties are studied. As an application a new simple proof of the characterization of the flag face numbers of balanced Cohen-Macaulay complexes originally due to Stanley (necessity) and Björner, Frankl, and Stanley (sufficiency) is given. The necessity portion of their result is generalized to certain conditions on the face numbers and Betti numbers of balanced Buchsbaum complexes.


MATEMATIKA ◽  
2017 ◽  
Vol 33 (1) ◽  
pp. 97
Author(s):  
Saugata Purkayastha ◽  
Dr. Jituparna Goswami ◽  
Bhargab Debnath

In this work, we have introduced the notion of hyperperfect group. A group of order n is said to be hyperperfect if there exists a natural number k such that n-1 = k[σ(n)-n-1] where σ(n) denotes the sum of positive divisors of n. We have also established a condition under which a cyclic group is hyperperfect. We have established that no group of prime order is hyperperfect and investigated the same for groups of various non-prime order. We have also determined an upper bound of the order of a hyperperfect group.



2002 ◽  
Vol 69 ◽  
pp. 117-134 ◽  
Author(s):  
Stuart M. Haslam ◽  
David Gems ◽  
Howard R. Morris ◽  
Anne Dell

There is no doubt that the immense amount of information that is being generated by the initial sequencing and secondary interrogation of various genomes will change the face of glycobiological research. However, a major area of concern is that detailed structural knowledge of the ultimate products of genes that are identified as being involved in glycoconjugate biosynthesis is still limited. This is illustrated clearly by the nematode worm Caenorhabditis elegans, which was the first multicellular organism to have its entire genome sequenced. To date, only limited structural data on the glycosylated molecules of this organism have been reported. Our laboratory is addressing this problem by performing detailed MS structural characterization of the N-linked glycans of C. elegans; high-mannose structures dominate, with only minor amounts of complex-type structures. Novel, highly fucosylated truncated structures are also present which are difucosylated on the proximal N-acetylglucosamine of the chitobiose core as well as containing unusual Fucα1–2Gal1–2Man as peripheral structures. The implications of these results in terms of the identification of ligands for genomically predicted lectins and potential glycosyltransferases are discussed in this chapter. Current knowledge on the glycomes of other model organisms such as Dictyostelium discoideum, Saccharomyces cerevisiae and Drosophila melanogaster is also discussed briefly.



2020 ◽  
Vol 8 (1) ◽  
pp. 114-165
Author(s):  
Tetsu Toyoda

AbstractGromov (2001) and Sturm (2003) proved that any four points in a CAT(0) space satisfy a certain family of inequalities. We call those inequalities the ⊠-inequalities, following the notation used by Gromov. In this paper, we prove that a metric space X containing at most five points admits an isometric embedding into a CAT(0) space if and only if any four points in X satisfy the ⊠-inequalities. To prove this, we introduce a new family of necessary conditions for a metric space to admit an isometric embedding into a CAT(0) space by modifying and generalizing Gromov’s cycle conditions. Furthermore, we prove that if a metric space satisfies all those necessary conditions, then it admits an isometric embedding into a CAT(0) space. This work presents a new approach to characterizing those metric spaces that admit an isometric embedding into a CAT(0) space.



Author(s):  
Azadeh Assadi ◽  
Peter C. Laussen ◽  
Patricia Trbovich

Background and aims: Children with congenital heart disease (CHD) are at risk of deterioration in the face of common childhood illnesses, and their resuscitation and acute management is often best achieved with the guidance of CHD experts. Access to such expertise may be limited outside specialty heart centers and the fragility of these patients is cause for discomfort among many emergency medicine physicians. An understanding of the differences in macrocognition of these clinicians could shed light on some of the causes of discomfort and facilitate the development of a sociotechnological solution to this problem. Methods: Cardiac intensivists (CHD experts) and pediatric emergency medicine physicians (non-CHD experts) in a major academic cardiac center were interviewed using the critical decision method. Interview transcripts were coded deductively based on Klein’s macrocognitive framework and inductively to allow for new or modified characterization of dimensions. Results: While both CHD-experts and non-CHD experts relied on the macrocognitive functions of sensemaking, naturalistic decision making and detecting problems, the specific data and mental models used to understand the patients and course of therapy differed between CHD-experts and non-CHD experts. Conclusion: Characterization of differences between the macrocognitive processes of CHD experts and non-CHD experts can inform development of sociotechnological solutions to augment decision making pertaining to the acute management of pediatric CHD patients.



2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Juan Pablo Sáenz ◽  
Mónica Paola Novoa ◽  
Darío Correal ◽  
Bell Raj Eapen

Background. The use of mobile applications in dermatology to support remote diagnosis is gaining acceptance, particularly in rural areas, where dermatology services are commonly managed by healthcare personnel with no specialty training. Moreover, ontologies—sets of concepts that represent knowledge in a given domain—are increasingly being used to support medical diagnosis. A specific case is ONTODerm: an ontology to aid dermatological diagnosis. However, there is little information on the combined use of mobile applications and ontologies as support solutions in dermatology. Objective. Assessing the reliability of ONTODerm as a tool to support remote dermatological diagnosis when used together with a mobile dermatological application in underprivileged areas. Methods. A mobile application that allows characterization of skin lesions was developed, and the information about the lesions was sent to ONTODerm. An exploratory study was conducted in a remote area without access to a dermatologist. A total of 64 dermatological queries were recorded in the application and consulted with ONTODerm. Later, an experienced dermatologist evaluated the characterization and diagnosis of each query to determine the accuracy of the system. Results. The results showed that the probability of obtaining a correct diagnosis was between 64.4% and 85.6% with a confidence interval of 95%. A higher accuracy rate was obtained when the skin lesion occurred on the face or when its border was categorized as poorly demarcated. Conclusions. This study demonstrates the implementation of a teledermatology strategy based on mobile applications and domain ontology-driven knowledge base to provide timely assistance to healthcare professionals. This approach was found to be pertinent in the Colombian rural context, particularly in forest regions, where dermatology specialists are not available. The results of this article do not represent a final validation of the proposed approach; they suggest how the ontology can be improved to effectively support medical staff in marginalized regions.



2021 ◽  
Author(s):  
Molly Kozminsky ◽  
Thomas Carey ◽  
Lydia L. Sohn

Lipid-based nanoparticles have risen to the forefront of the COVID-19 pandemic—from encapsulation of vaccine components to modeling the virus, itself. Their rapid development in the face of the volatile nature of the pandemic requires high-throughput, highly flexible methods for characterization. DNA-directed patterning is a versatile method to immobilize and segregate lipid-based nanoparticles for subsequent analysis. DNA-directed patterning selectively conjugates oligonucleotides onto a glass substrate and then hybridizes them to complementary oligonucleotides tagged to the liposomes, thereby patterning them with great control and precision. The power of this method is demonstrated by characterizing a novel recapitulative lipid-based nanoparticle model of SARS-CoV-2 —S-liposomes— which present the SARS-CoV-2 spike (S) protein on their surfaces. Patterning of a mixture of S-liposomes and liposomes that display the tetraspanin CD63 into discrete regions of a substrate is used to show that ACE2 specifically binds to S-liposomes. Importantly, DNA-directed patterning of S-liposomes is used to verify the performance of a commercially available neutralizing antibody against the S protein. Ultimately, the introduction of S-liposomes to ACE2-expressing cells demonstrates the biological relevance of DNA-directed patterning. Overall, DNA-directed patterning enables a wide variety of custom assays for the characterization of any lipid-based nanoparticle.



2004 ◽  
Vol 178 ◽  
pp. 521-523
Author(s):  
Agnes S. Ku

Fairbrother's Toward Critical Patriotism is a timely publication in the “Hong Kong Culture and Society” series: political squabbles and conflicts over the idea of patriotism in the context of the national security legislation in Hong Kong are inflamed following the spectacular mass demonstration by 500,000 people on 1 July 2003. As the author points out, patriotism and nationalism are relatively recent historical phenomena in China. In mainland China, Marxist-Leninism became the guiding ideology after 1949. Yet, from the early 1980s, in the face of a legitimacy crisis, the leadership shifted toward patriotism as a unifying and justificatory ideology while professing ultimate objectives in line with Marxist principles. In Hong Kong, civic education had been de-emphasized under the ideology of de-politicization by the colonial government until the handover in the 1990s. The book rejects the typical characterization of Hong Kong students as simply having a weak sense of patriotism and nationalism, and of mainland students as patriotic dupes under the state and presents a more nuanced analysis.



2016 ◽  
Vol 19 (3) ◽  
pp. 475
Author(s):  
Federico Gabriel Burdman

http://dx.doi.org/10.5007/1808-1711.2015v19n3p475In this paper I look into a problem concerning the characterization of the main conceptual commitments of the ‘post-cognitivist’ theoretical framework. I will firs consider critically a proposal put forth by Rowlands (2010), which identifie the theoretical nucleus of post-cognitivism with a convergence of the theses of the extended and the embodied mind. The shortcomings I fin in this proposal will lead me to an indepedent and wider issue concerning the apparent tensions between functionalism and the embodied and enactive approaches. I will then discuss the standing of embodied, enactive and extended approaches in the face of the dividing issue concerning functionalism, with an eye on the possibility of divorcing the thesis of the extended mind of its original formulation in functionalist terms. In this way, I shall consider the outlook of overcoming some of the conceptual tensions in post-cognitivism by thinking its theoretical framework as non-functionalist.



10.37236/3414 ◽  
2013 ◽  
Vol 20 (4) ◽  
Author(s):  
Sarah Behrens ◽  
Catherine Erbes ◽  
Michael Ferrara ◽  
Stephen G. Hartke ◽  
Benjamin Reiniger ◽  
...  

A sequence of nonnegative integers is $k$-graphic if it is the degree sequence of a $k$-uniform hypergraph. The only known characterization of $k$-graphic sequences is due to Dewdney in 1975. As this characterization does not yield an efficient algorithm, it is a fundamental open question to determine a more practical characterization. While several necessary conditions appear in the literature, there are few conditions that imply a sequence is $k$-graphic. In light of this, we present sharp sufficient conditions for $k$-graphicality based on a sequence's length and degree sum.Kocay and Li gave a family of edge exchanges (an extension of 2-switches) that could be used to transform one realization of a 3-graphic sequence into any other realization. We extend their result to $k$-graphic sequences for all $k \geq 3$. Finally we give several applications of edge exchanges in hypergraphs, including generalizing a result of Busch et al. on packing graphic sequences.



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