Modeling Changes in Internal Pressure During the Solidification of Hydrous Granitic Intrusives: Implications for the Crystallization of Miarolitic Pegmatites

Author(s):  
Issac J. Jacques ◽  
Alan J. Anderson

ABSTRACT Volatile exsolution is widely recognized as an important trigger for eruptions from shallow magma reservoirs, but relatively few studies quantify the effects of exsolution on internal pressure within deeper-seated intrusive bodies. We present a model to predict internal pressure changes during the crystallization of a haplogranite melt containing 3 and 5 mass % H2O and with an emplacement pressure of 200 MPa. Mass and volume relations between phases are used to determine internal pressure assuming a closed, constant-volume system. The results indicate that initial crystallization of alkali feldspar and quartz causes a decrease in pressure prior to the exsolution of an aqueous fluid from the residual melt (i.e., resurgent boiling). Further crystallization toward the core of the body in the presence of a separate volatile phase results in a sharp increase in internal pressure. Our model shows that in closed, isochoric systems, the crystallization of the H2O-saturated melt will generate internal pressures that greatly exceed emplacement pressures typical of miarolitic pegmatites. Extreme overpressure modifies the physical and chemical properties of the residual melt and coexisting aqueous fluid, which in turn influences crystallization kinetics and the development of primary textures. Primary melt and fluid inclusions in pocket minerals thus likely represent samples trapped at various pressures in a rapidly evolving melt–fluid system. In most pegmatites, increasing fluid pressure and the formation of large pockets is regulated by the permeability and tensile strength of the enclosing rock. This explains why many miarolitic pegmatites occur within rigid host rocks such as granite, gabbro, and gneiss.

Author(s):  
O.G. Drugova ◽  
◽  
A.A. Fedoruk ◽  
T.N. Shtin

Abstract. Due to the predominance of PM1 particles in the air samples, the following metals were found in the aerosol: copper, zinc, silicon, iron, lead, sulfur, arsenic, aluminum, antimony, tin, magnesium, cadmium and several other metals. The content of sulfates was significantly noted. These physical and chemical properties show a considerable toxic potential of industrial aerosol. The MPC of lead, sulfur and silicon dioxides, as well as nitrogen oxides and formaldehyde were detected in the working air. Meanwhile, copper, zinc, and iron did not exceed their MPC. Moreover, an underestimation of the aerosol was observed within the framework of industrial control. It has been found that the aerosol components may have an irritating, reprotoxic, allergenic, and carcinogenic effect on the body. Further consideration of the dispersed and chemical composition of the aerosol is required to determine the concentration of identified substances in the working air and the limiting components determining its biological effect.


2015 ◽  
Vol 19 (2) ◽  
pp. 39-50
Author(s):  
Inna Tiurikova ◽  
Mykhailo Peresichnyi

Abstract The results of studies in the field of beverage functionality using walnut are presented. The main components such as celery, Jerusalem artichokes, carrots, pumpkin and rhubarb, as a dietary supplement - extracts from walnut of milk-maturity stage are offered for creating blends. The basic physical and chemical properties of fruit and vegetable raw materials and semi-finished products created on the base of them have been studied, and their nutritional and biological value has been proved. Rational technologies of fruit and vegetable blends with nut additives have been identified. Their biological value has been confirmed. Drinks are recommended for use in the daily diet of human beings to satisfy thirst and enrich the body by biologically valuable components.


Nanomedicine ◽  
2019 ◽  
Vol 14 (20) ◽  
pp. 2763-2775 ◽  
Author(s):  
Fatih Zor ◽  
Fatma Nurefsan Selek ◽  
Giuseppe Orlando ◽  
David F Williams

Biocompatibility is a very common word that is used within biomaterial science and used for description of the interactions between the foreign material and the body. However, the meaning of biocompatibility as well as the mechanisms that collectively constitutes is still unclear. With the advance of nanotechnology, new concerns have been observed related to biocompatibility of these biomaterials. Due to their small size and variability of their physical and chemical properties, nanoparticles’ (NP) distribution within the body and interactions with the target cells and tissues are highly variable. Here, we tried to provide an overview about NPs, the concept of biocompatibility and biocompatibility-related issues in nanomedicine and several different NPs.


2015 ◽  
Vol 66 (2) ◽  
pp. 97-108 ◽  
Author(s):  
Veno Kononenko ◽  
Mojca Narat ◽  
Damjana Drobne

Abstract When nanoparticles enter the body, their interactions with cells are almost unavoidable. Unintended nanoparticle interaction with immune cells may elicit a molecular response that can have toxic effects and lead to greater susceptibility to infectious diseases, autoimmune disorders, and cancer development. As evidenced by several studies, nanoparticle interactions with biological systems can stimulate inflammatory or allergic reactions and activate the complement system. Nanoparticles can also stimulate immune response by acting as adjuvants or as haptens. Immunosuppressive effects have also been reported. This article gives a brief review of in vitro and in vivo research evidencing stimulatory or suppressive effects of nanoparticles on the immune system of mammals. In order to ensure safe use of nanosized particles, future research should focus on how their physical and chemical properties influence their behaviour in the biological environment, as they not only greatly affect nanoparticle-immune system interactions but can also interfere with experimental assays


Author(s):  
B.M. Kussainova ◽  
◽  
G.K. Tazhkenova ◽  
I.A. Kazarinov ◽  
◽  
...  

The problem of creating and using sorption materials is relevant for the practice of modern chemistry, biotechnology, medicine and agriculture. Knowledge of the physical and chemical laws of the processes of carbonation, activation, as well as sorption and desorption is of particular importance in the case of nanostructured carbon sorbent for highly effective treatment of water contaminated with pesticides, as well as for reducing the concentration of cytokines in the blood of patients with sepsis. It is of great practical importance to obtain adsorbents using a carbon sorbent to significantly reduce the concentrations of heavy substances, which is very important for the Western regions of Kazakhstan. Thus, it is currently relevant to develop such sorbents that would have high mechanical strength and withstand high fluid pressure during operation, have a large capacity and high wear resistance, allowing them to work for a year or more. Based on the above, the goal of our research is to create new modified carbon sorbents for industrial use for wastewater treatment.


2021 ◽  
Vol 14 (2) ◽  
pp. 48-55
Author(s):  
C. N. Buzdalkin ◽  
N. G. Vlasova ◽  
A. V. Rozhko ◽  
V. N. Bortnovsky

The Republican Research Center for Radiation Medicine and Human Ecology in the Internal and External Emergency Plans of the Belarusian nuclear power plant is specified as an institution that provides specialized treatment for personnel, as well as persons from the population living in the emergency zone of the station. The plant is the first facility in the Republic that used nuclear energy. There is no experience in treating radiation injuries in Belarus. This is the first time that the National Health Service has been assigned the task of ensuring readiness for the reception and specialized treatment of people who have been exposed to emergency or unplanned radiation. The purpose of the work is to establish criteria for radiation exposure for use in a Belarusian specialized medical institution in case of medical response to radiological accidents. As a result of the analysis of publications of international organizations, the criteria of radiation exposure that can be applied in the conditions of Belarusian specialized medical institutions were selected. Assessment of the criteria was made taking into account existing national technical regulations and the available capabilities of emergency response participants. To account for the quality of radiation in relation to deterministic effects “Gy-equivalent” is used. The criteria include both dosimetric values for cases of external and internal accidental and unplanned exposure, and levels of radioactive substances with unknown physical and chemical properties entering the body that require urgent medical intervention. Criteria for cases of surface contamination of skin and wounds require separate consideration.


2021 ◽  
Vol 15 (1) ◽  
pp. 055-062
Author(s):  
Aliyu Haruna Sani ◽  
Musa Amanabo

Heavy metal toxicity over the years has been proven to be a source of diverse health risks. Thou these metals, play certain biological roles, they are in excess amount get accumulated in the body and food chain displaying a chronic effect in the long run. Lead toxicity is an important environmental disease and its effects on the human body are devastating with its toxicity dependent upon the absorbed dose, the route of exposure as well as the duration of exposure. There is almost no function in the human body which is not affected by lead toxicity. Lead is highly persistent in the environment and because of its continuous use, its levels rise in almost every country particularly in developing countries like Nigeria where it occupies unique physical and chemical properties that make it suitable for a large number of applications. Various public health measures have been undertaken to control, prevent and treat lead toxicity occurring at various levels, such as occupational exposure, accidents and environmental factors. This article reviews the works listed in scientific literatures with recent updates regarding the toxicity of lead. Focus is also on the biomarkers of lead toxicity on the renal, hematological and oxidative stress conditions.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 701
Author(s):  
Paulina García-Estrada ◽  
Miguel A. García-Bon ◽  
Edgar J. López-Naranjo ◽  
Dulce N. Basaldúa-Pérez ◽  
Arturo Santos ◽  
...  

Intraocular/Intravitreal implants constitute a relatively new method to treat eye diseases successfully due to the possibility of releasing drugs in a controlled and prolonged way. This particularity has made this kind of method preferred over other methods such as intravitreal injections or eye drops. However, there are some risks and complications associated with the use of eye implants, the body response being the most important. Therefore, material selection is a crucial factor to be considered for patient care since implant acceptance is closely related to the physical and chemical properties of the material from which the device is made. In this regard, there are two major categories of materials used in the development of eye implants: non-biodegradables and biodegradables. Although non-biodegradable implants are able to work as drug reservoirs, their surgical requirements make them uncomfortable and invasive for the patient and may put the eyeball at risk. Therefore, it would be expected that the human body responds better when treated with biodegradable implants due to their inherent nature and fewer surgical concerns. Thus, this review provides a summary and discussion of the most common non-biodegradable and biodegradable materials employed for the development of experimental and commercially available ocular delivery implants.


2021 ◽  
Vol 14 (4) ◽  
pp. 1983-1991
Author(s):  
Nagham Mahmood Aljamali ◽  
Sabrean Farhan Jawad

The importance of research lies in the treatment of cancerous tumors due to the spread of cancerous tumors in recent decades, so researchers have to insist on finding alternative and more treatments safe from chemotherapy and radiation, which are derivatives of some amino acids, which we attended in our current research. Also, some research showed that taking tryptophan for 3 days before exercise can improve energy and efficiency during exercise, but other preliminary research shows that taking tryptophan during exercise does not improve endurance during cycling exercises. For a few days before exercise to notice any benefit. In this research, we prepared derivatives of cyclic tryptophan and studied their efficacy as anti-tumors, and they gave good results in reducing the size of cancerous tumors and reducing their spread in the body., then sympathy all synthesized new cyclic-tryptophan compounds by numerous techniques (FT.IR ,H.NMR)–spectrophotometric, other physical and chemical properties ,with studying for one of new prepared derivatives as anti breast cancer.


2020 ◽  
Vol 67 ◽  
pp. 107-146
Author(s):  
Paul Martin Holm ◽  
Niels-Ole Prægel

The Kærven Syenite Complex (KSC) is one of the oldest felsic intrusions in the Tertiary East Greenland province. Here we update our previous description of the KSC and supply a greatly expanded and comprehensive geochemical dataset. New data allow us to present a more detailed petrogenetic model for the evolution of the KSC and to investigate the geochemical characteristics of igneous cumulates subjected to loss and, occasionally, replacement of residual liquid. The KSC comprises eleven mappable units that generally young westwards. Rock types range from quartz syenite to quartz alkali feldspar syenite and alkali feldspar granite. Individual intrusive units are relatively narrow and steep-sided and are collectively suggested to represent a ring dyke complex. Basement gneiss and gabbro host rocks have locally contaminated the oldest quartz syenite KSC unit, but most of the main part of the complex escaped significant influence from host rocks. A late suite of E–W to NE–SW striking peralkaline dykes of trachytic to phonolitic compositions intrude the KSC. Compositions of the KSC rocks span a considerable range in SiO2, 59–73 wt%. Concentrations of several elements vary widely for a given SiO2 (especially at SiO2 < 66 wt%), and variation diagrams do not suggest a single model for the evolution of the units of the complex. A cumulative origin is envisaged for several KSC units. Geochemical modelling suggests that KSC magmas were derived from more than one primary magma, and that the complex evolved through a four-stage process: fractional crystallisation in precursory magma chambers was followed by final emplacement of each unit, establishment of a crystal/melt mush, expulsion of part of the residual melt and, finally, crystallisation of the remaining melt. Trace element disequilibria between alkali feldspar and host rocks in two closely associated quartz alkali feldspar syenite units indicate that highly evolved residual melt was replaced by a less evolved melt phase. Modelling of potential parent melt compositions to the Kærven magmas suggests an origin not in the Iceland plume asthenosphere, but rather in a moderately enriched source, possibly in the continental lithosphere. The course of melt evolution by fractional crystallisation is indicated to have taken place in magma chambers at depth, and repeated rise of magma into the upper crustal magma chambers and crystallisation there formed the KSC. Based on our survey of published geochemical data, the inferred parental magmas seem to have few equivalents in the North Atlantic Igneous Province and may have been generated mainly from melting of enriched dry lithospheric mantle of possibly Archaean age.


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