scholarly journals Cell, Time and Knowledge: Some Conjectures

2021 ◽  
Vol 2 (5) ◽  
pp. 408-411
Author(s):  
Diosey Ramon Lugo-Morin

The impact that the COVID-19 pandemic has had on global institutions and populations has been unprecedented. The health measures (e.g., confinement and social distancing) recommended by WHO and adopted by most nations in the world have not contained the spread of COVID-19. Vaccine development is expected to be a decisive element in controlling the pandemic, however, poor countries do not have immediate access to developed vaccines, which means that the COVID-19 pandemic will be present for some time among low-income countries. Against this daunting backdrop, it is necessary to explore more universal and inclusive ways of combating the COVID-19 pandemic and all future pandemics. Three conjectures are proposed that lead to a single path, unlocking the knowledge that cells have been able to accumulate over time. Although it may seem impossible in practice, the theory shows that knowledge exists to reach the frontiers of DNA.

2020 ◽  
Vol 12 (21) ◽  
pp. 9091
Author(s):  
Luis Miguel Lázaro Lorente ◽  
Ana Ancheta Arrabal ◽  
Cristina Pulido-Montes

There is a lack of concluding evidence among epidemiologists and public health specialists about how school closures reduce the spread of COVID-19. Herein, we attend to the generalization of this action throughout the world, specifically in its quest to reduce mortality and avoid infections. Considering the impact on the right to education from a global perspective, this article discusses how COVID-19 has exacerbated inequalities and pre-existing problems in education systems around the world. Therefore, the institutional responses to guaranteeing remote continuity of the teaching–learning process during this educational crisis was compared regionally through international databases. Three categories of analysis were established: infrastructure and equipment, both basic and computer-based, as well as internet access of schools; preparation and means of teachers to develop distance learning; and implemented measures and resources to continue educational processes. The results showed an uneven capacity in terms of response and preparation to face the learning losses derived from school closure, both in low-income regions and within middle- and high-income countries. We concluded that it is essential to articulate inclusive educational policies that support strengthening the government response capacity, especially in low-income countries, to address the sustainability of education.


2021 ◽  
Author(s):  
Osama Aziz

Poverty is one of the main issues faced by countries across the world. Over the last three decades, governments and international organizations such as the World Bank, the IMF, etc. have been trying to reduce poverty. Despite this, today almost 2.5 billion people are still living in poverty. Entrepreneurship is often seen as a way to reduce poverty. Moreover, the role of entrepreneurship facilitators is very important in creating a suitable business environment for entrepreneurs which increases the capacity of entrepreneurial activities. The purpose of this thesis is to provide an insight into how entrepreneurial activity and entrepreneurship facilitators (Government, Incubators, and Financial Institutions) help in improving the business environment in all countries and hence in poverty alleviation, examining the impact in case of high-income, high medium-income, medium-income, low-income countries and, as a result, reduce poverty. To investigate this, the Human Development Index (HDI) has been used to measure poverty. Secondary data for Entrepreneurship (Entrepreneurial Facilitators, Entrepreneurial Activities, and Economic Factors) and Poverty (HDI)) from the period of 2005 to 2016 are used for high-income countries, high medium-income countries, medium-income countries and low-income countries. The study has found that there is a positive and significant relationship between entrepreneurial activity and the changes in Human Development Index (HDI) in all countries studied over the 12 years period. It also finds that the presence of good entrepreneurial facilitators improves the capacity of entrepreneurial activity which reduces poverty as measured by the HDI. It adds to the body of knowledge by using HDI as a new tool to analyze the impact of entrepreneurial activity country wise. It also suggests that governments need to make better business related regulations which will motivate entrepreneurs and create ease of business doing. Finally it suggests that trade openness bring foreign investments in a country which create employment for people.


2021 ◽  
Author(s):  
Osama Aziz

Poverty is one of the main issues faced by countries across the world. Over the last three decades, governments and international organizations such as the World Bank, the IMF, etc. have been trying to reduce poverty. Despite this, today almost 2.5 billion people are still living in poverty. Entrepreneurship is often seen as a way to reduce poverty. Moreover, the role of entrepreneurship facilitators is very important in creating a suitable business environment for entrepreneurs which increases the capacity of entrepreneurial activities. The purpose of this thesis is to provide an insight into how entrepreneurial activity and entrepreneurship facilitators (Government, Incubators, and Financial Institutions) help in improving the business environment in all countries and hence in poverty alleviation, examining the impact in case of high-income, high medium-income, medium-income, low-income countries and, as a result, reduce poverty. To investigate this, the Human Development Index (HDI) has been used to measure poverty. Secondary data for Entrepreneurship (Entrepreneurial Facilitators, Entrepreneurial Activities, and Economic Factors) and Poverty (HDI)) from the period of 2005 to 2016 are used for high-income countries, high medium-income countries, medium-income countries and low-income countries. The study has found that there is a positive and significant relationship between entrepreneurial activity and the changes in Human Development Index (HDI) in all countries studied over the 12 years period. It also finds that the presence of good entrepreneurial facilitators improves the capacity of entrepreneurial activity which reduces poverty as measured by the HDI. It adds to the body of knowledge by using HDI as a new tool to analyze the impact of entrepreneurial activity country wise. It also suggests that governments need to make better business related regulations which will motivate entrepreneurs and create ease of business doing. Finally it suggests that trade openness bring foreign investments in a country which create employment for people.


2021 ◽  
Vol 26 (1) ◽  
pp. 64-73
Author(s):  
Nataliya Kuznetsova ◽  

Abstract. Introduction. International migration is an important socio-economic indicator of the development of states and a regulator of socio-economic relations in the international economy. Under the modern conditions of development of the world society migration processes are characterized by dynamic development and scale of distribution. Today, international migration is becoming an important factor influencing the formation of international reality, causing social changes and cultural interaction of countries involved in migration process. Purpose. The modern world is diverse in its development and progress. Existing asymmetries and inequalities in most countries, conflicts, poverty, climate change encourage people from the low-income countries to migrate to the economically developed countries in searching of a safer and better life. In addition, the COVID-19 pandemic carries great threats to the lives and health of migrants, negatively affects their spatial mobility, and creates the new societal challenges and dangers. That is why the author of the article aims to explore the main trends in the formation of modern migration flows and changes in international migration; to identify global factors influencing the dynamics of international migration and to identify key issues that need to be corrected in the management system of international migration at the global level. Results. The author has analyzed the current trends in the development of international migration in the global space, assesses the formation of the main migration flows in terms of individual sub-regions and countries. According to the results of the analysis, the growing influence of exogenous factors (interstate conflicts, economic and political instability in the world, climate change, etc.) and endogenous factors (low level of social protection of the low-income countries, limited access to vital public resources), high levels of corruption in some countries that cause poverty, carry threat and danger to the lives and health of their citizens) to increase the dynamics of migration flows in the world. During the studying the author has formed the main group of countries (USA, Canada, Luxembourg, Norway, Switzerland, Germany, France, Czech Republic, others), which (according to the long-term UN forecasts) will increase net migration rates and net numbers of migrants; this information is the important indicators for governments of these countries in order to respond in a timely manner and put changes into their existing migration policies. The tools of integration of international migrants into the national societies of the host countries of Europe in terms of employment, education, social inclusion have been considered. The benefits of the host countries from successful integration have been determined. The impact of the COVID-19 pandemic on the change in the dynamics of international migration has been studied and the key problems of international migration development that need to be corrected at the global international level due to the intensification of crisis situations have been identified. Conclusions. Thus, the acceleration of migration processes and the scale of their spread in the world have a great impact on significant changes in foreign economic relations between countries; the macroeconomic dynamics of their development is gaining new momentum. The mechanical movement of the population causes changes in the structure of human capital, affects the quality of its formation and development. Due to the unevenness and the existing asymmetry in the socio-economic development of the world, the migration factor can become a major tool for the destruction of economic stability of many countries, the intensification of crises in the social sphere. Therefore, the existing problems of global cooperation and coordination of international migration, the lack of effective mechanisms for interaction between national and global levels of migration management need to be solved in time. The international regulatory framework for the protection of migrants' rights in the global dimension needs to be improved.


Vaccines ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 341 ◽  
Author(s):  
Olufemi Samuel Folorunso ◽  
Olihile M. Sebolai

Safety, efficacy, and cost-effectiveness are paramount to vaccine development. Following the isolation of rotavirus particles in 1969 and its evidence as an aetiology of severe dehydrating diarrhoea in infants and young children worldwide, the quest to find not only an acceptable and reliable but cost-effective vaccine has continued until now. Four live-attenuated oral rotavirus vaccines (LAORoVs) (Rotarix®, RotaTeq®, Rotavac®, and RotaSIIL®) have been developed and licensed to be used against all forms of rotavirus-associated infection. The efficacy of these vaccines is more obvious in the high-income countries (HIC) compared with the low- to middle-income countries (LMICs); however, the impact is far exceeding in the low-income countries (LICs). Despite the rotavirus vaccine efficacy and effectiveness, more than 90 countries (mostly Asia, America, and Europe) are yet to implement any of these vaccines. Implementation of these vaccines has continued to suffer a setback in these countries due to the vaccine cost, policy, discharging of strategic preventive measures, and infrastructures. This review reappraises the impacts and effectiveness of the current live-attenuated oral rotavirus vaccines from many representative countries of the globe. It examines the problems associated with the low efficacy of these vaccines and the way forward. Lastly, forefront efforts put forward to develop initial procedures for oral rotavirus vaccines were examined and re-connected to today vaccines.


2021 ◽  
Vol 4 (1) ◽  
pp. 39
Author(s):  
Amanze Nkemjika Ikwu ◽  
David Chinasa Igwe ◽  
Sixtus Ezenwa Nwawudu ◽  
Adeyemi Samuel Adebayo

The ravaging Corona virus caused many countries of the world to impose partial or total lockdown, African nations inclusive. Most African countries are low-income countries, with most of the population being non-office workers. With the continued spread and rise of COVID-19 in many African nations, the people had no choice but to keep working for their daily survival. Moreover, the current health system in most African countries is weak and unable to tackle the emerging COVID-19 pandemic. The extra burden of the COVID-19 pandemic exposed these gaps and weaknesses. In addition to the effect of the pandemic on Africa's healthcare system, there is an equal and parallel debilitating effect of the virus on the psychosocial lives of Africans. Regardless of the several challenges that African nations face; Is there any way forward? African leaders may be able to unite and reduce their dependency on the international community for aids during health crises. They may also collectively take proactive decisions on strengthening their health systems as they work on educating their people.


Author(s):  
Haytham M. A. Kaafarani

The CRASH-2 trial is a randomized controlled trial performed in more than 270 hospitals across the world and aimed at studying the impact of tranexamic acid (TXA), an anti-fibrinolytic agent, on mortality in trauma patients presenting with hemorrhagic shock. With more than 20,000 patients, CRASH-2 showed a small but statistically significant decrease in mortality from 16% to 14.5% (p < 0.05), without any increase in thromboembolic events, in patients who received TXA versus placebo. Subset analyses suggested that the benefit was only present if TXA was administered within 3 h from injury. Two main criticisms of the study are (1) TXA reduced mortality but not the number of blood products used or the percentage of patients who needed transfusion, raising questions regarding the mechanism by which the drug worked; (2) the conductance of the study in moderate- to low-income countries, limiting its generalizability to high-income countries with advanced trauma systems.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
M-Nasan Abdul Baki ◽  
Mahmoud Alhaj Hussein

AbstractHealth sciences research is a major tool in exchanging publications and knowledge between the various countries of the world. Researchers in developing countries barely have any financial funding from governmental or educational institutes to support their research. In low-income countries such as Syria, With less than 30$ per month and almost no financial support, Syrian residency doctors are fighting to push the scientific research reality of this ongoing crisis country forward and without a doubt, APC waiver plays a crucial role in this continuing mission.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Deborah Bedoll ◽  
Marta van Zanten ◽  
Danette McKinley

Abstract Background Accreditation systems in medical education aim to assure various stakeholders that graduates are ready to further their training or begin practice. The purpose of this paper is to explore the current state of medical education accreditation around the world and describe the incidence and variability of these accreditation agencies worldwide. This paper explores trends in agency age, organization, and scope according to both World Bank region and income group. Methods To find information on accreditation agencies, we searched multiple online accreditation and quality assurance databases as well as the University of Michigan Online Library and the Google search engine. All included agencies were recorded on a spreadsheet along with date of formation or first accreditation activity, name changes, scope, level of government independence, accessibility and type of accreditation standards, and status of WFME recognition. Comparisons by country region and income classification were made based on the World Bank’s lists for fiscal year 2021. Results As of August 2020, there were 3,323 operating medical schools located in 186 countries or territories listed in the World Directory of Medical Schools. Ninety-two (49%) of these countries currently have access to undergraduate accreditation that uses medical-specific standards. Sixty-four percent (n = 38) of high-income countries have medical-specific accreditation available to their medical schools, compared to only 20% (n = 6) of low-income countries. The majority of World Bank regions experienced the greatest increase in medical education accreditation agency establishment since the year 2000. Conclusions Most smaller countries in Europe, South America, and the Pacific only have access to general undergraduate accreditation, and many countries in Africa have no accreditation available. In countries where medical education accreditation exists, the scope and organization of the agencies varies considerably. Regional cooperation and international agencies seem to be a growing trend. The data described in our study can serve as an important resource for further investigations on the effectiveness of accreditation activities worldwide. Our research also highlights regions and countries that may need focused accreditation development support.


Author(s):  
Brendon Stubbs ◽  
Kamran Siddiqi ◽  
Helen Elsey ◽  
Najma Siddiqi ◽  
Ruimin Ma ◽  
...  

Tuberculosis (TB) is a leading cause of mortality in low- and middle-income countries (LMICs). TB multimorbidity [TB and ≥1 non-communicable diseases (NCDs)] is common, but studies are sparse. Cross-sectional, community-based data including adults from 21 low-income countries and 27 middle-income countries were utilized from the World Health Survey. Associations between 9 NCDs and TB were assessed with multivariable logistic regression analysis. Years lived with disability (YLDs) were calculated using disability weights provided by the 2017 Global Burden of Disease Study. Eight out of 9 NCDs (all except visual impairment) were associated with TB (odds ratio (OR) ranging from 1.38–4.0). Prevalence of self-reported TB increased linearly with increasing numbers of NCDs. Compared to those with no NCDs, those who had 1, 2, 3, 4, and ≥5 NCDs had 2.61 (95% confidence interval (CI) = 2.14–3.22), 4.71 (95%CI = 3.67–6.11), 6.96 (95%CI = 4.95–9.87), 10.59 (95%CI = 7.10–15.80), and 19.89 (95%CI = 11.13–35.52) times higher odds for TB. Among those with TB, the most prevalent combinations of NCDs were angina and depression, followed by angina and arthritis. For people with TB, the YLDs were three times higher than in people without multimorbidity or TB, and a third of the YLDs were attributable to NCDs. Urgent research to understand, prevent and manage NCDs in people with TB in LMICs is needed.


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