scholarly journals Frequency of Thyrotoxicosis in Patient with One Sided Exophthalmos

2020 ◽  
Vol 8 (2) ◽  
pp. 81-84
Author(s):  
Tahreem Zafar ◽  
Shumaila Perveen ◽  
Nisar Khan ◽  
Salman Khan ◽  
Tahseen Ahmed
Keyword(s):  
Sinus Thrombosis ◽  
Case Series ◽  
Posterior Segment ◽  
Medical Department ◽  
Female Ratio ◽  
Duration Of Illness ◽  
Associated Symptoms ◽  
The Common ◽  
Male To Female ◽  
Orbital Rim

Background: Thyroid associated Opthalmo-pathy is a condition of lid retraction causing a staring appearance. This occurs in any form of thyrotoxicosis as a result of sympathetic overactivity.Exophthalmos is the forward protrusion of eye ball beyond the orbital rim. Material & Methods: This case series was observed in medical department Mufti Mehmood Teaching Hospital DIKhan, Pakistan over a period of eight months from February 2018 to September 2018. Detailed history with reference of duration of illness, mode of onset, progression and associated symptoms like fever, pain, diplopia and loss of vision was taken. Complete examination of orbit, eyelid, anterior and posterior segment was done. Routine Investigations along with special diagnostic tests like TFTs and MRI were performed to aid etiological diagnosis. Results: A total 47 patients were observed during this study period. Out of these 20 (21.27%) were male and 27 (57.44%) were female with male to female ratio 1:1.35 with mean age of 32 years. Out of 47 patients30 (63.82%) patients were having thyrotoxicosis as a cause of exophthalmos, 10(21.27%) were having retrobulbartumour, 5(10.63%) patients were with cavernous sinus thrombosis and 2(4.25%) patients were having idiopathic cause of exophthalmos. Conclusion: Thyrotoxicosis is the common cause of one sided exophthalmos and should be considered in all patients with one sided exophthalmos.

scholarly journals CARCINOMA OF URINARY BLADDER;

2017 ◽  
Vol 24 (11) ◽  
pp. 1691-1696
Author(s):  
Khalid Hussain ◽  
Manzoor Ahmad Khan ◽  
Attiq ur Rahman Khan ◽  
Imran Amin ◽  
Muhammad Khalid Butt
Keyword(s):  
Bladder Tumor ◽  
Tnm Classification ◽  
Case Series ◽  
Female Ratio ◽  
Voiding Symptoms ◽  
Case Series Study ◽  
And Gender ◽  
Muscle Invasive ◽  
Male To Female ◽  
Gross Haematuria

Introduction: The most common presentation of carcinoma of urinarybladder is haematuria. Almost 80-90% of patients with carcinoma of bladder present eitherwith microscopic or gross haematuria and it is mostly intermittent rather than constant. Somepatients also complain of irritative voiding symptoms such as frequency, urgency and dysuria.Study Design: Descriptive, case series study. Setting: Department of Urology, DHQ Hospital,Gujranwala, Pakistan. Period: July 2015 to June 2016. Materials & Methods: Total 30 patientsirrespective of age and gender with diagnosis of bladder tumor based on clinical symptomsand supported by laboratory tools like Urine cytology, Ultrasound and IVU were included. Thealready diagnosed patients of bladder tumor that have been treated with different modalitieswere excluded. All the tumors were staged according to TNM classification after TURBT andgraded on the basis of histopathology. Results: Mean age was 53.17+16.07SD years. Maleswere 25(83.3%) and females were 5(16.7%). Male to female ratio is 5:1. Twenty eight (93.3%)patients out of 30 presented with painless haematuria. 23(73.33%) patients out of 30 patientswere smokers. 09 (30%) patients had Ta, in which G1 was found in 2 patients and G2 in 7patients. T1 was found in 10 (33.3%) patients, in which G2 was 5(17.3%) and G3 was 5(17.3%)cases. Muscle invasive T2a was diagnosed in 04 patients amongst them G2 and G3 wasdetected in 2(6.6%) patients each respectively. T2b was present in 3 patients, which had G1 in1(3.3%) and G3 in 2(10%) patients. T3b G2 was found 01 patient and T3b G3 was detected in1(3.3%) patient, T4M1 G3 was present in 2(6.6%) patients. Conclusion: This study concludedthat the bladder tumor is quite common with muscle invasive TCC is more common. Painlesshematuria is the commonest presentation and also smoking has a definite association with CAbladder.

Operative management of external auditory canal cholesteatoma: case series and literature review

2013 ◽  
Vol 127 (9) ◽  
pp. 859-866 ◽  
Author(s):  
M Sayles ◽  
H A Kamel ◽  
F F Fahmy
Keyword(s):  
External Auditory Canal ◽  
Case Series ◽  
Operative Management ◽  
External Ear ◽  
Ear Canal ◽  
Female Ratio ◽  
External Ear Canal ◽  
Temporal Bones ◽  
External Auditory Canal Cholesteatoma ◽  
Male To Female

AbstractObjectives:To describe the clinical features of external auditory canal cholesteatoma, and to assess the outcome following bony meatoplasty with tragal cartilage and perichondrium graft repair.Methods:A retrospective review was carried out, comprising all patients with external auditory canal cholesteatoma who presented between January 2007 and December 2011. Patients underwent pre-operative audiometry and computed tomography imaging of the temporal bones, before undergoing bony meatoplasty via a postauricular incision. Pre- and post-operative comparisons were made of patients' otological symptoms and the otoscopic appearance of the external ear canal.Results and conclusion:Eight patients were included in the analyses. The median age of patients was 46.5 years (range 14–68 years), with a male to female ratio of 1:1. The median length of follow up was 16 months. The most common presenting features were unilateral otalgia and purulent otorrhoea. All patients had relatively advanced disease at presentation, with erosion of the temporal bone. All patients underwent bony meatoplasty via a postauricular approach to eradicate the disease. Bony meatoplasty was successful in the definitive management of external ear canal cholesteatoma.

scholarly journals HEMORRHAGIC STROKE;

2014 ◽  
Vol 21 (06) ◽  
pp. 1204-1208
Author(s):  
Faisal Shahab ◽  
Irfan Murtaza Shahwani ◽  
Shuaib Ansari ◽  
Syed Zulfiquar Ali Shah
Keyword(s):  
Blood Pressure ◽  
Hemorrhagic Stroke ◽  
Case Series ◽  
Health Sciences ◽  
Hypertensive Retinopathy ◽  
Age Group ◽  
Female Ratio ◽  
Case Series Study ◽  
Male To Female ◽  
Series Study

Objectives: To identify the frequency of risk factors in hemorrhagic stroke at Liaquat university of medical and health sciences. Patient and methods: This Descriptive case series study of six months was carried out in the department of medicine, Liaquat University of Medical and Health Sciences. Patients aged 20-70 years of age with hemorrhagic stroke on CT were enrolled in the study after taking consent from caretaker of patients. Detailed history focusing on hypertension, diabetes and smoking and their duration was taken. Blood pressure was recorded and fundoscopy was done to find out diabetic or hypertensive retinopathy. Thorough neurological examination and fasting / random blood glucose level was evaluated while the data was done was analyzed using SPSS version 16. Results: A total of 100 patients were included in the study during study period. 61% of patients were in > 50 years of age group with mean age of 53.4±11 years. A total of 66 (66%) were male; with male to female ratio was 2:1. Hypertension was present in 63% of cases, Diabetes was found in 24% cases and 44 patients were cigarette smokers. Conclusions: It was concluded that high blood pressure, diabetes mellitus and smoking are associated with hemorrhagic stroke.

scholarly journals Preoperative Factors Associated with Postoperative Diabetes Insipidus after Transsphenoidal Pituitary Adenectomy

2019 ◽  
Vol 16 (3) ◽  
pp. 55-57
Author(s):  
Sagar Koirala ◽  
Suresh Bishokarma ◽  
Dinesh Nath Gongal
Keyword(s):  
Pituitary Adenomas ◽  
Functional Type ◽  
Gold Standard Method ◽  
Female Ratio ◽  
Male Preponderance ◽  
Patient Size ◽  
Onset Of Diabetes ◽  
The Common ◽  
Male To Female ◽  
Preoperative Factors

Transsphenoidal pituitary adenectomy is the gold standard method of treatment of pituitaryadenomas. Post-operative diabetes insipid sis one of the common complication of this procedure. In this study we have analyzed pre-operative factors that may be associated with onset of diabetes insipid us following this procedure. A retrospective study of five years was conducted in a tertiary neurosurgical center. Histologically proven cases of pituitary adenomas who underwent transsphenoidalpituitary adenectomy were included in the study. Age and sex of the patients along with size and functional type of tumor were analyzed to see if they predicted the occurrence of diabetesinsipidus post-operatively. Out of 49 cases who underwent transsphenoidalpituitary surgery, 46 cases were proven to be pituitary adenomas histologically. There was male preponderance with male to female ratio of2:1. Age ranged from 15 to 72 with median age of 37 years. Nonfunctional, prolactinomas and growth hormone secreting tumors, were 25, 16and 4 in number. Median size of the tumor was2.35 in largest diameter. Out of these patients13 (28%) patients developed diabetes insipid us. Age, sex of the patient, size of the tumor and functional type of the tumor did not predict the incidence. Age, sex of the patient, size of the tumor and functional type of the tumor do not predict the incidence of diabetes insipid us post-operatively in patients undergoing transsphenoidal pituitaryadenectomy.

scholarly journals Paracoccidioidomycosis in the state of Maranhão, Brazil: geographical and clinical aspects

2012 ◽  
Vol 45 (3) ◽  
pp. 385-389 ◽  
Author(s):  
Wilma Batista de Matos ◽  
Gisele Maria Campelo dos Santos ◽  
Vitor Emmanuel Bouças da Silva ◽  
Eloísa da Graça do Rosário Gonçalves ◽  
Antonio Rafael da Silva
Keyword(s):  
Rural Areas ◽  
Case Series ◽  
The State ◽  
Clinical Aspects ◽  
Direct Examination ◽  
Female Ratio ◽  
Central Regions ◽  
Clinical Description ◽  
Two Stages ◽  
Male To Female

INTRODUCTION: The study aimed to show the situation of paracoccidioidomycosis in the state of Maranhão, Brazil. METHODS: This study is a descriptive case series developed in two stages. First, a survey of cases originating from the state of Maranhão at the Instituto de Doenças Tropicais Natan Portela, Piauí (IDTNP) from 1997 to 2007, and second, the clinical description of 29 cases diagnosed in the Centro de Referências em Doenças Infecciosas e Parasitárias, Maranhão (CREDIP) from 2004 to 2010. RESULTS: Two hundred and sixteen cases have been cataloged at the IDTNP. West, east, and central regions of the state of Maranhão recorded 90.3% of cases proving to be important areas for study. The western region, with a prevalence of 10.8/100,000 inhabitants, has a significantly higher proportion of cases than the northern, southern, and eastern regions (p < 0.05). The occurrence was higher in men with 89.3% of cases, and the male-to-female ratio was 8.4:1. The majority of patients were older than 20 years, lived in rural areas, and had farming or soil management as main occupation (73.8%). At CREDIP, 29 cases were diagnosed, of which 26 (89.6%) had multifocal manifestations. Mucous tissues were involved more (75.8%) frequently, followed by lymph nodes, skin, and lungs with 65.5%, 39% and 37.9 %, respectively. The diagnosis was made by combining direct examination, culture, and histopathology. CONCLUSIONS: The study shows the geographical distribution and the epidemiological and clinical aspects of paracoccidioidomycosis, revealing the significance of the disease to the state of Maranhão.

scholarly journals Diaphragmatic Hernia with Atypical Presentation - A Case Series

2014 ◽  
Vol 32 (1) ◽  
pp. 45-50
Author(s):  
SMA Shahid ◽  
MN Ali ◽  
M Ahmed ◽  
SS Islam ◽  
SB Hossain
Keyword(s):  
Diaphragmatic Hernia ◽  
Case Series ◽  
College Hospital ◽  
Female Ratio ◽  
Medical College ◽  
Chest X Ray ◽  
The Mean ◽  
Challenging Situation ◽  
Male To Female ◽  
Diaphragmatic Hernias

Congenital Diaphragmatic Hernia is one of the most challenging diagnosis faced by pediatric surgeons. From the time of its first anatomic description more than 300 years ago, CDH has carried a high mortality rate. We aimed to review patients who presented with hernia of diaphragm during the last six months. In this retrospective study, the medical records of three patients treated for diaphragmatic hernias who were admitted to Rajshahi Medical College Hospital between July 2012 and December 2012 were analyzed. Three patients with age of 45 days to 7 years were included in the study. Male to female ratio was 1:2. All patients had left-sided diaphragmatic hernia. Chest X-ray was obtained from all patients which was diagnostic. One patient needed thoracotomy incision. No patient required mesh repair. The mean hospitalization time was 14 days. There was no postoperative death. Diaphragmatic hernia is an uncommon and challenging situation for the surgeon. Prompt diagnosis and treatment prevent serious morbidity and mortality associated with complications such as gangrene and perforation of herniated organ. DOI: http://dx.doi.org/10.3329/jbcps.v32i1.21050 J Bangladesh Coll Phys Surg 2014; 32: 45-50

scholarly journals Benign fibro-osseous lesions of the jaws: a clinicopathologic study of 98 Tanzanian patients

2019 ◽  
Vol 25 (4) ◽  
pp. 38
Author(s):  
Ntokozo C. Dube ◽  
Jeremiah Robert Moshy ◽  
Edda A. Vuhahula ◽  
Karpal Singh Sohal
Keyword(s):  
Fibrous Tissue ◽  
Giant Cells ◽  
Ossifying Fibroma ◽  
Female Ratio ◽  
Histological Features ◽  
Fibrous Stroma ◽  
Clinicopathologic Study ◽  
Woven Bone ◽  
The Common ◽  
Male To Female

Introduction: The benign fibro-osseous lesions (BFOL) are characterized by replacement of the normal bone by cellular fibrous tissue containing various forms of ossification. They encompass common clinical, radiologic and histopathological features and hence pose considerable diagnostic and therapeutic challenges to clinicians and pathologists. Objective: To analyze the clinico-pathological and radiological features of BFOLs of the jaws in patients treated at Muhimbili National Hospital, Tanzania. Material and methods: A retrospective study of files of patients who were diagnosed with BFOLs from January 2011 to December 2013 was done. The collected information included data on demographic characteristics, the duration of the lesion, location of the lesion, presence of swelling, associated symptoms and reported radiological and histological features. Results: A total of 98 patient's records were retrieved. There was a predominance of females (59, 60.2%), with a male to female ratio of 1:1.5. The patient's age at presentation ranged from 5 years to 75 years with a mean age of 29.81 ± 15.28 years. Four types of BFOLs were encountered. Ossifying fibroma were the most frequent (61.2%), followed by fibrous dysplasia (19.4%). Maxilla was more affected than the mandible. Majority (>70%) of the BFOLs were radio-opaque. The common histological features in all four types of BFOL included presence of: woven bone in fibrous stroma, giant cells, loose collagen and foci of hemorrhage. Conclusion: In this sample, BFOLs, were slightly more prevalent in females than males, affecting individuals below 40 years at large. They showed several overlapping clinical, radiological and histological features; thus a combination of different modalities seems necessary for an accurate diagnosis.

scholarly journals Lemierre’s Syndrome: A Thing of the Past?

2020 ◽  
Author(s):  
Nehal Dhaduk ◽  
Sudeepti Vedula ◽  
Aparna Govindan ◽  
Evelyne Kalyoussef
Keyword(s):  
Mortality Rate ◽  
Case Reports ◽  
Case Series ◽  
Lemierre’S Syndrome ◽  
Female Ratio ◽  
Clinical Presentations ◽  
Life Threatening ◽  
Lemierre's Syndrome ◽  
High Index Of Suspicion ◽  
Male To Female

Abstract Introduction: Lemierre’s syndrome (LS), infectious thrombophlebitis of the internal jugular vein, is a rare, life-threatening complication of oropharyngeal infections underrepresented in literature. We reviewed the etiology, clinical characteristics, treatment regiments and prognosis of LS in pediatric patients.Methods: PubMed and MEDLINE were searched from February 10, 2018 to July 28, 2018 for relevant studies. A systematic review was performed using the terms LS and pediatric case. Our criteria included reviews, case reports, and case series with patients under 18 years with a diagnosis of LS. Results: 70 cases of pediatric LS were identified. The male to female ratio was 1:1.7 with an average age of 10.7 years (5 weeks to 17 years). The most common initial clinical presentations were fever (90.0%), sore throat (38.6%), and neck pain or tenderness (35.7%), while the most frequent findings on physical exam were fever (31.4%) and neck involvement (28.6%). F. necrophorum was the predominant organism cultured (62.9%). Septic emboli were seen in 51.4% of cases with the lungs affected in 40 patients. Most commonly used treatments were antibiotics (91.4%) followed by anticoagulation (50.0%) and the overall mortality rate was 8.6%. The average time from initial presentation to diagnosis was 4.9 days. Conclusion: LS is a deadly condition with a staggering mortality rate despite the advent of antibiotic measures. Early identification and a high index of suspicion are necessary to prevent complications associated with LS. Despite its rarity it should remain on the differential for any patient with toxic signs and localized neck findings.

scholarly journals Clinicopathological Profile of Rhabdomyosarcoma in Children

2012 ◽  
Vol 30 (3) ◽  
pp. 132-136
Author(s):  
Umme Habiba Begum ◽  
Afiqul Islam
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Mass Lesion ◽  
Female Ratio ◽  
Head And Neck Region ◽  
Clinicopathological Profile ◽  
Common Clinical Presentation ◽  
The Common ◽  
Medical University ◽  
Male To Female

Objectives: To describe the clinical profile as well as  histopathological sub-types of Rhabdomyosarcoma in  children.Methods: A hospital base prospective observational study  was conducted among 20 diagnosed cases of  Rhabdomyosarcoma in children, those attending in  Hemato-Oncology department of Bangabandhu Sheikh  Mujib Medical University (BSMMU), Dhaka in the period  between January to December 2009.Results: The peak incidence of Rhabdomyosarcoma was  in 1-5 years of age group (n=9, 45%) with mean age 6.83  years with male to female ratio 5.66:1. The common sites  of primary tumor was in head and neck region (40%, n=08),  followed by genito-urinary tract, 30% (n=06), extremities  20% (n=04), trunk 10% (n=02). The most common clinical  presentation was mass lesion 100% (n=20), followed by local  pain 25% (n=05), urinary obstructions 15% (n=03)  dysphagia, chronic otorrhea, dysuria, haematuria, and  proptoses were 10% each (n=02, each); The histological  sub-types were Embryonal 60% (n=12), alveolar 30% (n=6),  and Botryoid 10% (n=02); Of Embryonal variety in head  and neck region 58.33% (n=7), and Genito-urinary sites  41.67% (n=5); of Alveolar variety in trunk 66.67% (n=4),  and in extremities33.33% (n=2), of Botryoid sub-type  frequency was equal in head - neck region and genitourinary  site 50% each (n=1).Conclusion: Children with Rhabdomyosarcoma presented mostly in 1 to 5 years of age, with mass lesion (100%),  predominantly in head and neck region (40%) and the  commonest histological sub-type was Embryonal variety  (60%). DOI: http://dx.doi.org/10.3329/jbcps.v30i3.12461 J Bangladesh Coll Phys Surg 2012; 30: 132-136

scholarly journals Common Site of Urinary Calculi in Kidney, Ureter and Urinary Bladder Region: Jos Experience

2019 ◽  
Vol 7 (10) ◽  
Author(s):  
Samuel Moses Danjem ◽  
Salaam AJ ◽  
Kolade- Yunusa HO ◽  
Shuaibu SI
Keyword(s):  
Urinary Bladder ◽  
Urinary Calculi ◽  
Renal Stones ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Common Location ◽  
The Common ◽  
Male To Female

Objective: To determine the common location of calculus along the urinary tract using CT scan.  Methods: This cross sectional study was conducted using CT from November 2016 to September 2018, in a tertiary hospital in Jos, Nigeria. The CT images acquired from this period were evaluated and 50 patients were positive for urolithiasis. The data was subjected to statistical analysis based on age, gender and calculus location. Results: Out of the 50 patients with calculi, 34 were males and 16 were females with a male to female ratio of 2.13:1. 137 urinary calculi were documented in which 90 were in males and 47 in the female patients. Highest occurrence of calculi was seen in age group 31-40 years (34.0%). 112(82%) were renal stones, 12(9%) were ureteric stones, 8(6%) were found in pelvi-ureteric junction (PUJ), 3(2%) were in the vesico-ureteric junction (VUJ), 2(1%) were in the urinary bladder and none in the urethra. Conclusion: Kidney stones are the most common followed by the ureter, the pelvi-ureteric junction, the vesico-ureteric junction and the bladder.  

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