scholarly journals Alteraciones Neurológicas por virus Zika: Revisión bibliográfica. (Neurological Alterations by the Zika virus: Bibliographic review)

2019 ◽  
Vol 38 (3) ◽  
Author(s):  
Anastasia Bellido Sokol
Keyword(s):  
Nervous System ◽  
Risk Factor ◽  
Virus Infection ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Adult Population ◽  
Age Group ◽  
Neurological Alterations ◽  
Virus Zika ◽  
Zika Fever

<p>[Neurological Alterations by the Zika virus]</p><p><strong>Resumen</strong> <br />El propósito de la siguiente revisión es establecer la relación documentada entre las alteraciones del sistema nervioso y la presencia de la infección por el virus Zika. El virus Zika, perteneciente a la familia de Flaviviridae, es el responsable de la fiebre del Zika y en la mayoría de casos la manifestación clínica se presenta en forma leve en la población adulta. <br /><br />El mayor interés se atribuye a los recién nacidos por ser el grupo etario más afectado a nivel neurológico por la virulencia del Zika. La presencia del transmisor del virus, mosquito hembra Aedes aegypti en el territorio de Panamá, representa un factor de riesgo para el aumento de la incidencia de la microcefalia en recién nacidos. <br /><br /><strong>Abstract</strong> <br />The purpose of the following review is to establish the documented relationship between alterations of the nervous system and the presence of Zika virus infection. Zika virus, forming part of the Flaviviridae family, is responsible for the Zika fever and in most cases the clinical manifestation occurs mildly in the adult population. <br /><br />The greatest interest is attributed to newborns since it is the age group that is mostly affected at the neurological level by the virulence of Zika. The presence of the viral transmitter, mosquito Aedes aegypti in the territory of Panama, represents a risk factor for the increase in the incidence of microcephaly in newborns.<br /><br /><br /></p>

scholarly journals Prevenção da infecção pelo zika vírus nas gestantes

2017 ◽  
Vol 11 (12) ◽  
pp. 5339
Author(s):  
Daiane Santos ◽  
Mariana Alves Pimenta ◽  
Flavio Bittencourt ◽  
Murilo Cesar Nascimento ◽  
Silvana Maria Coelho Leite Fava ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Zika Virus ◽  
Health Workers ◽  
Family Health ◽  
Cross Sectional Study ◽  
Prevention Measures ◽  
Cross Sectional ◽  
Exact Test ◽  
Quantitative Descriptive ◽  
Virus Zika

RESUMOObjetivo: avaliar as competências dos ACS no desenvolvimento das atribuições esperadas e definidas pelo Ministério da Saúde nas ações de pré-natal de risco habitual, desenvolvidas no âmbito da ESF, em relação à prevenção da infecção pelo zika vírus na gestação. Método: estudo quantitativo, descritivo, transversal, com coleta de dados em 14 equipes da Estratégia de Saúde da Família, mediante um questionário com três partes: A (enfrentamento ao Aedes aegypti); B (pré-natal de baixo risco) e C (medidas de prevenção pessoal contra o Zika vírus), analisadas por agrupamentos e pelo Teste Exato de Fisher. Resultados: melhor desempenho foi observado em B, seguido de A. As maiores dificuldades estavam relacionadas com a atividade C. Conclusão: há um panorama favorável de atuação desses profissionais, embora com dificuldades quanto à alimentação dos sistemas de informação, à baixa participação comunitária e à pouca integração com o trabalho das equipes. Descritores: Enfermagem; Agente Comunitário de Saúde; Zika Vírus.ABSTRACT Objective: to evaluate the competences of the ACS in the development of the attributions expected and defined by the Ministry of Health in the habitual, risk prenatal actions, developed within the scope of the FHS, in relation to the prevention of infection by the zika virus during pregnancy. Method: quantitative, descriptive, cross-sectional study with data collection in 14 teams of the Family Health Strategy, through a questionnaire with three parts: A (coping with Aedes aegypti); B (low risk prenatal) and C (personal prevention measures against Zika virus), analyzed by clusters and Fisher's Exact Test. Results: better performance was observed in B, followed by A. The greatest difficulties were related to activity C. Conclusion: there is a favorable panorama of these professionals, although with difficulties in feeding information systems, low community participation and little integration with the work of the teams. Descritores: Nursing; Community Health Workers; Zika Virus.RESUMEN Objetivo: evaluar las competencias de los ACS en el desarrollo de las atribuciones esperadas y definidas por el Ministerio de Salud en las acciones de prenatal de riesgo habitual, desarrolladas en el marco de la ESF, en relación a la prevención de la infección por el zika virus en la gestación. Método: estudio cuantitativo, descriptivo, transversal, con recolección de datos en 14 equipos de la Estrategia de Salud de la Familia, mediante un cuestionario con tres partes: A (enfrentamiento al Aedes aegypti); B (prenatal de bajo riesgo) y C (medidas de prevención personal contra el Zika virus), analizadas por agrupaciones y por la prueba exacta de Fisher. Resultados: mejor desempeño fue observado en B, seguido de A. Las mayores dificultades estaban relacionadas con la actividad C. Conclusión: hay un panorama favorable de actuación de estos profesionales, aunque con dificultades en cuanto a la alimentación de los sistemas de información, a la baja participación comunitaria y a la poca integración con el trabajo de los equipos. Descritores: Enfermería; Agentes Comunitarios de Salud; Vírus Zika.

scholarly journals PREVALENCE OF SMOKING IN ADULT POPULATION OF IRKUTSK

2016 ◽  
Vol 1 (6) ◽  
pp. 153-156
Author(s):  
Максикова ◽  
Tatyana Maksikova ◽  
Бабанская ◽  
Evgeniya Babanskaya ◽  
Меньшикова ◽  
...  
Keyword(s):  
Risk Factor ◽  
Adult Population ◽  
Age Groups ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Noncommunicable Diseases ◽  
Age Difference ◽  
Age Group ◽  
Considerable Problem ◽  
The One

Smoking is a significant risk factor of chronic noncommunicable diseases. Smoking prevalence is variable in different populations. A study of the prevalence of this risk factor allows to estimate its contribution to the development of cardiovascular pathology, to plan the necessary amount of medical care for people using tobacco, and to determine the effectiveness of prevention activities in the region. As a result of the study, smoking frequency in population of the Irkutsk region older 18years of age or over was established as 29.5%. The number of smokers increased with age, reaching maximum value of 38.6% in the group 30–39 years. Male smokers made maximum in the age group 30–39 years, women – in the age group of 18–19 years. The average age of smokers was 34 years, the one of nonsmokers – 43 years. The age difference was 9 years, and it was lower in the group of men than in the group of women (5 and 11 years, respectively). The number of the smoking men were 3 times larger, than women: 50.2% and 13.5%, respectively. Among persons with arterial hypertension, 22.1% were smoking with the maximum frequency of smoking in age groups from 20 to 49 years. These figures point to a considerable problem of smoking in the region.

scholarly journals Direito Fundamental à Sáude: microcefalia e políticas sanitárias para combate do Zika Virus

2018 ◽  
Vol 14 (3) ◽  
pp. 235
Author(s):  
Sandra Maciel-Lima ◽  
Francisco Cardozo Oliveira ◽  
Isabela Moreira Domingos
Keyword(s):  
Aedes Aegypti ◽  
Zika Virus ◽  
Virus Zika

O presente artigo retrata o Direito fundamental à saúde e Políticas de Saneamento Básico como mecanismos propulsores para o desenvolvimento humano. A partir da análise do Plano de Enfrentamento Nacional para o Combate ao Vírus Zika (ZIKV), busca-se abordar a microcefalia como uma emergência sanitária de alcance global. Até a presente data, mais de 48 países já notificaram a transmissão do vírus Zika: América do Norte; América Central; Caribe e, em especial, a América do Sul, com maior número de incidência. Razão pela qual, requer a mobilização das autoridades públicas e a sociedade através de movimentos de conscientização, investimento em tecnologia, pesquisas e infraestrutura básica para a eliminação do vetor Aedes Aegypti no território brasileiro.

scholarly journals Experimental Zika virus infection in Aedes aegypti: Susceptibility, transmission & co-infection with dengue & chikungunya viruses

2018 ◽  
Vol 147 (1) ◽  
pp. 88 ◽  
Author(s):  
DevendraT Mourya ◽  
MangeshD Gokhale ◽  
TriparnaD Majumdar ◽  
PragyaD Yadav ◽  
Vimal Kumar ◽  
...  
Keyword(s):  
Virus Infection ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Zika Virus Infection

scholarly journals Zika Vírus e o Futuro da Odontologia no Atendimento a Pacientes com Microcefalia

2017 ◽  
Vol 9 (1) ◽  
pp. 58
Author(s):  
Sângela Maria da Silva Pereira ◽  
Alberto Sabin Moura Borba ◽  
Jaqueline De Fátima Lopes Rosa ◽  
Ceci Nunes Carvalho ◽  
Etevaldo Matos Maia Filho ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Aedes Albopictus ◽  
Zika Virus ◽  
Virus Zika

O Zika Vírus (ZIKV) é um arbovírus, que tem o ácido ribonucleico como seu material genético, pertence a família Flaviviridae e é transmitido principalmente pelos mosquitos Aedes aegypti e Aedes albopictus, tendo-se registros também da sua transmissão por fluídos corporais. Desde Maio de 2015 o Brasil enfrenta um surto do vírus, que se espalhou rapidamente pelas Américas causando preocupação devido a possível relação do vírus com a microcefalia, que foi detectada no líquido amniótico e placenta de mulheres com fetos microcéfalos. Os pacientes acometidos com microcefalia possuem um perímetro cefálico inferior à média para o sexo e idade, e na maioria dos casos está associado à estrutura cerebral alterada, problemas de desenvolvimento e características faciais dismórficas. Estas características afetam não apenas o estado de saúde geral do paciente, mais também o atendimento odontológico, que se torna dificultado devido ao pequeno número de profissionais habilitados para o atendimento a pacientes especiais e ao pouco conhecimento das características craniofaciais e dentárias destes indivíduos. O presente artigo tem como objetivo apresentar as características craniofaciais que influenciam no atendimento odontológico e uma perspectiva sobre o futuro da odontologia no atendimento dos pacientes acometidos com microcefalia. Palavras-chave: Microcefalia, manifestações orais, Vírus Zika

scholarly journals Therapeutic Approaches for Zika Virus Infection of the Nervous System

2017 ◽  
Vol 14 (4) ◽  
pp. 1027-1048 ◽  
Author(s):  
Rachel P. M. Abrams ◽  
Jamie Solis ◽  
Avindra Nath
Keyword(s):  
Nervous System ◽  
Virus Infection ◽  
Zika Virus ◽  
Therapeutic Approaches ◽  
Zika Virus Infection

scholarly journals Different populations of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) from Central Africa are susceptible to Zika virus infection

2020 ◽  
Vol 14 (3) ◽  
pp. e0008163 ◽  
Author(s):  
Basile Kamgang ◽  
Marie Vazeille ◽  
Armel Tedjou ◽  
Aurélie P. Yougang ◽  
Theodel A. Wilson-Bahun ◽  
...  
Keyword(s):  
Virus Infection ◽  
Aedes Aegypti ◽  
Aedes Albopictus ◽  
Zika Virus ◽  
Central Africa ◽  
Zika Virus Infection ◽  
Different Populations

scholarly journals Desafios para o controle e prevenção do mosquito aedes aegypiti

2017 ◽  
Vol 11 (12) ◽  
pp. 4913 ◽  
Author(s):  
Lays Santos França ◽  
Camilla Massaranduba Alves De Macedo ◽  
Sheylla Nayara Sales Vieira ◽  
Andresa Teixeira Santos ◽  
Gislene De Jesus Cruz Sanches ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Dengue Virus ◽  
Community Health ◽  
Zika Virus ◽  
Public Management ◽  
Prevention And Control ◽  
Structured Interview ◽  
Endemic Diseases ◽  
Virus Zika ◽  
And Control

RESUMOObjetivo: identificar os desafios enfrentados pelos agentes comunitários de saúde e agentes de combate a endemias na prevenção e controle da disseminação do mosquito Aedes aegypti. Método: estudo qualitativo realizado com 12 agentes comunitários de saúde e sete agentes de combate a endemias. Os dados foram produzidos a partir de entrevista semiestruturada e analisados com a técnica do Discurso do Sujeito Coletivo. Resultados: verificou-se que as maiores dificuldades enfrentadas por estes agentes são o descaso, a falta de compromisso e a conscientização da comunidade, além da gestão, que não se apresenta de modo efetivo no processo. Conclusão: propõe-se, assim, uma maior efetivação das ações de educação em saúde junto à população, investimento em educação permanente e sensibilização da gestão pública. Descritores: Prevenção e controle; Participação da Comunidade; Saúde Pública; Vírus da Dengue; Zika Vírus; Vírus Chikungunya.ABSTRACT Objective: to identify the challenges faced by community health agents and agents to combat endemic diseases in the prevention and control of the spread of the Aedes aegypti mosquito. Method: a qualitative study carried out with 12 community health agents and seven agents to combat endemic diseases. The data were produced from a semi-structured interview and analyzed using the Collective Subject Discourse technique. Results: it was verified that the greatest difficulties faced by these agents are the neglect, lack of commitment and awareness of the community, besides the management, that is not presented in an effective way in the process. Conclusion: it is proposed, therefore, a greater effectiveness of the actions of health education with the population, investment in permanent education and public management awareness. Descriptors: Prevention and Control; Community Participation; Public Health; Dengue Virus; Zika Virus; Chikungunya Virus.RESUMEN Objetivo: identificar los desafíos enfrentados por los agentes comunitarios de salud y agentes de combate a endemias en la prevención y control de la diseminación del mosquito Aedes aegypti. Método: estudio cualitativo, realizado con 12 agentes comunitarios de salud y siete agentes de combate a endemias. Los datos fueron producidos a partir de entrevista semiestructurada y analizados con la técnica del Discurso del Sujeto Colectivo. Resultados: se verificó que las mayores dificultades enfrentadas por estos agentes son el descuido, la falta de compromiso y la concientización de la comunidad, además de la gestión, que no se presenta de modo efectivo en el proceso. Conclusión: se propone, así una mayor efectividad de las acciones de educación en salud junto a la población, inversión en educación permanente y sensibilización de la gestión pública. Descriptores: Prevención y Control; Participación de la Comunidad; Salud Pública; Virus del Dengue; Virus Zika; Virus Chikungunya.

scholarly journals In vitro and in vivo co-infection and super-infection dynamics of Mayaro and Zika viruses in mosquito and vertebrate backgrounds

2021 ◽  
Author(s):  
Marco Brustolin ◽  
Sujit Pujhari ◽  
Cory A Henderson ◽  
Donghun Kim ◽  
Jason L Rasgon
Keyword(s):  
Virus Infection ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Negative Impact ◽  
Single Infection ◽  
Simultaneous Increase ◽  
Virus Family ◽  
Mayaro Virus ◽  
Super Infection

Factors related to increasing globalization and climate change have contributed to the simultaneous increase and spread of arboviral diseases. Co-circulation of multiple arboviruses in the same geographic regions provides impetus to study the impacts of multiple arbovirus infections in a single vector. In the present study we describe co-infection and super-infection with Mayaro virus (Family Togaviridae, genus Alphavirus) and Zika virus (family Flaviviridae, genus Flavivirus) in vertebrate cells, mosquito cells, and Aedes aegypti mosquitoes to understand the interaction dynamics of these pathogens and effects on viral infection, dissemination and transmission. In Aedes aegypti mosquitoes, co-infection has a negative impact on infection and dissemination rates for Zika virus, but not Mayaro virus, when compared to single infection scenarios, and super-infection of Mayaro virus with a previous Zika virus infection resulted in increased Mayaro virus infection rates. We found that co-infection and super-infection negatively affected Zika viral replication in vertebrate cells (Vero and Huh), resulting in the complete blockage of Zika virus replication in some scenarios. At the cellular level, we demonstrate that single vertebrate and insect cells can be simultaneously infected with Zika and Mayaro viruses. This study highlights the dynamics of arboviral co- and super-infections and emphasizes the importance of considering these dynamics during risk assessment in epidemic areas.

scholarly journals Zika virus infection drives epigenetic modulation of immunity by the histone acetyltransferase CBP of Aedes aegypti

2021 ◽  
Author(s):  
Anderson de Mendonca Amarante ◽  
Isabel Caetano de Abreu da Silva ◽  
Amanda Roberta Revoredo Vicentino ◽  
Vitor Coutinho Carneiro ◽  
Marcia de Amorim Pinto ◽  
...  
Keyword(s):  
Virus Infection ◽  
Aedes Aegypti ◽  
Zika Virus ◽  
Histone Deacetylases ◽  
Histone Acetyltransferase ◽  
Fat Body ◽  
Survival Rates ◽  
Immune Genes ◽  
Wide Range

Epigenetic mechanisms are responsible for a wide range of biological phenomena in insects, controlling embryonic development, growth, aging and nutrition. Despite this, the role of epigenetics in shaping insect-pathogen interactions has received little attention. Gene expression in eukaryotes is regulated by histone acetylation/deacetylation, an epigenetic process mediated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). In this study, we explored the role of the Aedes aegypti histone acetyltransferase CBP (AaCBP) after infection with Zika virus, focusing on the two main immune tissues, the midgut and fat body. We showed that the expression and activity of AaCBP could be positively modulated by blood meal and Zika infection. Nevertheless, Zika-infected mosquitoes that were silenced for AaCBP revealed a significant reduction in the acetylation of H3K27 (CBP target-marker), followed by downmodulation of the expression of immune genes, higher titers of Zika virus and lower survival rates. Importantly, in Zika-infected mosquitoes that were treated with sodium butyrate, a histone deacetylase inhibitor, their capacity to fight virus infection was rescued. Our data point to a direct correlation among histone hyperacetylation by AaCBP, upregulation of antimicrobial peptide genes and increased survival of Zika-infected-A. aegypti.

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