CLINICAL MANIFESTATIONS OF GASTROINTESTINAL TRACT DISEASES IN THE ORAL CAVITY IN CHILDREN OF BUKHARA

2020 ◽  
Vol 93 (1) ◽  
pp. 19-22
Author(s):  
S. Gafforov ◽  
◽  
J. Bakaev ◽  
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Medical Record ◽  
Digestive System ◽  
Clinical Manifestations ◽  
The State ◽  
Dental Examination ◽  
Pediatric Dentists

This article describes changes in the state of the oral cavity in the pathology of the digestive system, shows the main clinical manifestations of these processes and their relationship. The information presented in the work emphasizes the advisability of including the results of a dental examination in a medical record, which will optimize the work of both pediatric dentists and pediatricians.

scholarly journals SOME FEATURES OF THE RELATIONSHIP OF CLINICAL MANIFESTATIONS AND DENTAL INDICATORS OF LIFE QUALITY IN PATIENTS WITH REFRACTIVE ORAL CAVITIES AFTER ACID-RESPECT TERRITORY

2020 ◽  
Vol 16 (1) ◽  
pp. 22-29
Author(s):  
Irina Galimova ◽  
Irina Usmanova ◽  
Larisa Gerasimova ◽  
Zuhra Hismatullina ◽  
Yigal Granot ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Mucous Membrane ◽  
Clinical Features ◽  
Clinical Manifestations ◽  
Dental Examination ◽  
Relationship Of ◽  
The Relationship

Subject. The results of a comprehensive clinical examination of patients with acid-dependent diseases of the gastrointestinal tract, including an assessment of some features of the clinical manifestations of recurrent aphthalmic afta and dental quality of life parameters, are examined. The goal is to assess the relationship of the clinical manifestations of recurring aphthae of the oral cavity and the dental quality of life in patients with acid-dependent diseases of the gastrointestinal tract. Methodology. A general clinical and dental examination of 125 young people with recurrent aphthae of the oral cavity against acid-dependent diseases of the gastrointestinal tract was performed. The questionnaire method was used to assess the quality of life of the studied groups of patients depending on the nosology and clinical features of the pathology of the oral mucosa. Results. The percentage of patients with recurrent oral aphthae at the time of the clinical dental examination averaged 46.4 % of cases, with acid-dependent gastrointestinal diseases - 33.6%, the number of relapses averaged 2.57 ± 0.23 times a year. Among triggers of recurrent aphthae of the oral cavity, patients at the time of the clinical examination identified the influence of stressful situations (100 %), chronic diseases of the gastrointestinal tract (80 %), and mucosal injuries (33.6 %). Conclusions. The most frequent triggering factors that provoke the clinical features of recurrent aphthae of the oral cavity are some acid-dependent diseases of the gastrointestinal tract in the form of chronic gastritis and duodenitis and chronic pancreatitis against the background of hyperacid secretion of the stomach, and the mucous membrane is a favorite localization of morphological elements (aphthae) in the area of mesial incisors of the front teeth of the upper or lower jaw, the mucous membrane of the upper or lower lip, mucus melting the side surface of the tongue and the buccal mucosa in premolars.

scholarly journals FEATURES OF CLINICAL AND LABORATORY PARAMETERS AT THE PATIENS WITH RECURRENT ORAL AFTS AND CONDOMITANT ACID-DEPENDENT DISEASES OF THE GASTROINTESTINAL TRACT

2020 ◽  
Vol 16 (3) ◽  
pp. 23-29
Author(s):  
Irina Galimova ◽  
Rita Yunusova ◽  
Irina Usmanova ◽  
Larisa Gerasimova ◽  
Yigal Granot ◽  
...  
Keyword(s):  
Free Radical ◽  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Oral Hygiene ◽  
Oral Fluid ◽  
Free Radical Oxidation ◽  
The State ◽  
Radical Oxidation ◽  
Laboratory Parameters ◽  
Litmus Paper

Subject. Some features of the clinical picture, hygienic and microbiological state of the oral cavity, acidity and free-radical oxidation of the oral fluid in patients with recurrent aphthates on the background of acid-dependent diseases of the gastrointestinal tract are considered. The aim is to assess the relationship between clinical and laboratory parameters in patients with recurrent oral aphthae associated with acid-dependent diseases of the gastrointestinal tract. Methodology. A comprehensive clinical and laboratory examination of 58 young people with revealed recurrent aphthae of the oral cavity against the background of acid-dependent diseases of the gastrointestinal tract was carried out. The level of oral hygiene was assessed using the ONI-s index, the state of free-radical oxidation of the oral fluid - the "Chemilumimer-003" device, individual representatives of the normal flora were identified by inoculating the contents from the surface of aphthous elements on special differential diagnostic media of the HiCrome series. The acidity of the oral fluid was determined using a universal indicator litmus paper pH-1-14, short-term intragastric pHmetry was performed directly during fibrogastroduodenoscopy. Results. In 46.4 % of those examined, recurrent aphthae were found on the oral mucosa. In persons with chronic gastritis and duodenitis, the frequency of recurrences once a year was 37.9 %, 2-3 times a year ― 62.0, with the presence of chronic pancreatitis against the background of hyperacid gastric secretion ― 44.8 and 55.2, respectively. In patients with recurrent aphthae, a low level of oral hygiene, a violation of its microbiome, and a change in the acidity of the oral fluid were revealed. Conclusions. The presence of recurrent aphthae complicates individual oral hygiene, because accompanied by severe pain and paresthetic symptoms. This is manifested by an increase in the ONI-S index and a disturbance in the state of the normobiome in the form of an increase in the growth of resident microflora against the background of changes in the acidity of the oral fluid. Chemiluminescence indices correlate with the hygienic state of the oral cavity, qualitative changes in the normobiota and pH of the oral fluid in the studied clinical groups.

scholarly journals Dental status of professional athletes

2020 ◽  
Vol 101 (3) ◽  
pp. 365-370
Author(s):  
J G Hajiyev
Keyword(s):  
Oral Cavity ◽  
Oral Hygiene ◽  
Clinical Manifestations ◽  
Maximum Level ◽  
The State ◽  
Dental Status ◽  
Professional Athletes ◽  
Control Group ◽  
Periodontal Tissues ◽  
Periodontal Inflammation

Aim. To reveal the rate and severity of clinical manifestations of common dental diseases and dentofacial anomalies in professional athletes Methods. The effect of intense physical exertion and overtraining syndrome on the state of the organs and tissues of the dental system were examined in 200 professional athletes aged 1825 years between 2014 and 2016. Five groups where each has the same number of athletes (n=40) included: team sport athletes (volleyball, handball), martial arts athletes (wrestling, boxing), gymnasts, swimmers, athletes. The control group consisted of 40 individuals who were not professionally involved in sports. The state of the oral cavity, in particular periodontal tissues, was judged by changes in the following indicators: prevalence of dentofacial anomalies, the incidence of dental caries, state of the oral cavity hygienic using by simplified oral hygiene index (OHI-S) ( Green J.С., Vermillion J.R., 1963), degree of gums bleeding by using the MuhlemannCowell bleeding index, degrees of severity of periodontopathy by using the papillary-marginal alveolar index (RMA) [Massler, Schour (1949) in Parma modification (1960)]. Results. According to the values of the simplified oral hygiene index the worst state of the oral cavity hygienic was in wrestlers (2.120.022 points) and boxers (2.030.029) compared to the control group (1.620.026, p=0.049 and p=0.001, respectively). Catarrhal gingivitis and generalized chronic periodontitis are most often diagnosed in the groups of wrestling (82.56.01%), gymnastics (77.56.60%), boxing (70.07.25%) and swimming (70.07.25%). Dentoalveolar anomalies were more often detected in boxers (77.5% of cases, p=0.001) and in gymnasts (34.0%, p=0.365) compared to the control group. In these groups, diastema was also more often diagnosed. Conclusion. Periodontal inflammation indicators were higher in wrestlers and gymnasts groups compared to the dental status of all other groups of athletes; caries and maximum level of dental anomalies are more common for boxers.

scholarly journals SIGNS OF DISEASES OF THE GASTROINTESTINAL TRACT IN THE ORAL CAVITY OF CHILDREN

2021 ◽  
pp. 112-117
Author(s):  
A.I. Maksymenko
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Clinical Manifestations ◽  
Gastrointestinal Diseases ◽  
Pathological Process ◽  
Combined Lesions ◽  
Dental Diseases ◽  
Group B ◽  
Relationship Of ◽  
The Relationship

The question of combined lesions of the oral cavity and internal organs occupy a prominent place among the problems of dentistry nowadays. They allow to reflect the genesis of many diseases that manifest themselves in the oral cavity. Aim of the study was to analyze information on the relationship of diseases of oral cavity and various diseases of gastrointestinal tract. Anatomical and physiological proximity, common innervation and humoral regulation leads to the involvement of organs of oral cavity in the pathological process. Catarrhal gingivitis, stomatitis are often caused by deficiency of vitamins of group B. Above-mentioned deficiency is caused, according to many scientists, by the diseases of gastrointestinal tract. And such diseases of the oral cavity as chronic recurrent stomatitis, lichen planus, chronic recurrent herpetic stomatitis, chronic periodontitis depends on the pathology of the digestive tract. Conclusions. Thus, anatomical and physiological characteristics of children, who suffers from chronic gastrointestinal diseases, make us study the clinical manifestations of dental diseases in these patients. Prospects for further research. Further study of the dental status of children with diseases of the gastrointestinal tract is very valuable.

scholarly journals DIAGNOSTIC SIGNIFICANCE OF SOME REPRESENTATIVES OF NORMAL MICROBIOME OF THE ORAL CAVITY IN THE DEVELOPMENT OF RECOVERABLE ACTS OF THE ORAL CAVITY IN PATIENTS WITH ACID-DEPENDENT GASTROINTESTINAL DISEASES

2020 ◽  
Vol 15 (4) ◽  
pp. 31-37
Author(s):  
Irina Galimova ◽  
Irina Usmanova ◽  
Larisa Gerasimova ◽  
Marsel Tuigunov ◽  
Yigal Granot ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Clinical Manifestations ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Candida Spp ◽  
Diagnostic Significance ◽  
Detection Frequency ◽  
Enterococcus Spp ◽  
Staphylococcus Spp

Subject. The results of a comprehensive microbiological study of the state of the normobioma of the oral cavity in individuals with recurrent aphthae of the oral cavity against the background of acid-dependent diseases of the gastrointestinal tract are considered. The goal is to determine the diagnostic significance of individual representatives of the oral normobioma in patients with recurrent aphthae of the oral cavity against the background of acid-dependent diseases of the gastrointestinal tract. Methodology. The study involved 83 patients who were divided into two main and control groups depending on the clinical manifestations of recurrent aphthae of the oral cavity on the background of hypersecretory syndrome. Results. The results of the study showed that in patients of the first and second main groups, in which the manifestations of recurrent aphthae in the oral cavity were accompanied by diseases of the gastrointestinal tract with hypersecretory syndrome, the frequency of allocation of staphylococcal flora was 1.3—1.5 times higher compared to control (p≤0.05), an increase in the proportion of S. aureus — 2.5 times. The detection frequency of S. epidermidis in the control and both clinical groups was 28.0, 27.6 and 31.0 % of cases, respectively, the proportion of hemolytic forms in the control group was 4.0 %, in the first 10.3 % (an increase of 2 5 times), in the second — 17.2 % (4.3 times). The observed changes in the species composition may indicate dysbiosis in the oral cavity, caused not only by the presence of recurrent aphthae, but also by acid-dependent diseases of the gastrointestinal tract. Conclusions. In recurrent aphthae of the oral cavity in patients with acid-dependent diseases of the gastrointestinal tract in the microbiome of the oral cavity against the background of reduced titers of lactobacilli, an increase in representatives of Staphylococcus spp., Enterococcus spp is most often observed. and Candida spp. (1.2 times average), Enterococcus spp. (1.4 times), Staphylococcus spp. and Enterobacteriaceae spp. (1.2 times), Actinobacillus spp. (1.1 times).

Comparative analysis of polymorphic variants of IL-17A and MMP-1 genes with the risk of developing chronic periodontitis in petrochemical workers

2020 ◽  
Vol 60 (10) ◽  
pp. 687-693
Author(s):  
Iskander I. Zaidullin ◽  
Denis O. Karimov ◽  
Lilija K. Karimova ◽  
Milyausha F. Kabirova ◽  
Rasima R. Galimova ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Control Group ◽  
Periodontal Tissues ◽  
Dental Examination ◽  
Number Of Patients ◽  
Increased Risk ◽  
Harmful Substances

The susceptibility to the development and progression of inflammatory periodontal diseases, which depends on genetic and external factors (smoking, stress, oral hygiene), varies widely. In the development of these diseases, an important role is played not only by the presence of periodontal pathogenic microorganisms, but also by the presence of congenital or acquired immunodeficiency, immunoregulatory defects. The immune system plays a key role in the physiological and pathological processes of periodontal tissues. In this regard, IL17, produced by CD4+ Th cells, which has both Pro-inflammatory and protective activity, is of particular interest in the pathogenesis of periodontitis. The aim of study was to identify the relationship between polymorphic loci of the IL-17A (rs2275913) and MMP-1 (rs1799750) genes and clinical manifestations of chronic periodontitis in petrochemical workers. Dental examination was performed in 92 ethylene oxide production workers with chronic periodontitis and 74 patients with chronic periodontitis who did not come into contact with chemical factors (control group). Genotyping of polymorphisms rs2275913 of the IL17A gene and rs1799750 of the MMP1 gene was performed by allele-specific real-time polymerase chain reaction (PCR). Hygienic assessment of the degree of air pollution of the working area with harmful substances was carried out by gas chromatography according to the guidelines for the determination of harmful substances in the air № 5098-89, № 3119-84. When comparing the results of studies of both groups, there were no statistically significant differences in the frequency distributions of allelic variants and genotypes of the IL-17A and MMP-1 genes. The AA/AG genotypes of the IL-17A gene were associated with an increased risk of severe disease compared to the GG genotype in workers in the main group (OR=6.1; 95% CI 1.33-28.5; p=0.021) and in the control group (OR=7.26; 95% CI 1.34-39.25; p=0.016). Carriers of the A allele in the control group increased the risk of severe chronic periodontitis by 2.4 times compared to carriers of the G allele (OR=2.41; 95% CI 1.19-4.87; p=0.014). During the dental examination of employees of the ethylene oxide plant, the clinical course of periodontal diseases was more severe in comparison with the control group, and the number of patients with severe periodontitis was twice as high. It was found that the AA/AG genotypes of the IL-17A gene and the carrier of the A allele are associated with increased susceptibility to the development of severe chronic periodontitis. The association between the MMP-1 gene polymorphism and the risk of severe forms of chronic periodontitis has not been established. A risk factor for the development of inflammatory periodontal diseases in employees of the petrochemical complex is a complex of harmful production factors.

scholarly journals Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 271
Author(s):  
Saverio Capodiferro ◽  
Luisa Limongelli ◽  
Gianfranco Favia
Keyword(s):  
Early Diagnosis ◽  
Oral Cavity ◽  
Head And Neck ◽  
Clinical Outcomes ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Systemic Diseases ◽  
Special Issue ◽  
Hard Tissues ◽  
Current Special Issue

Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

scholarly journals Macronutrient Sensing in the Oral Cavity and Gastrointestinal Tract: Alimentary Tastes

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 667
Author(s):  
Russell Keast ◽  
Andrew Costanzo ◽  
Isabella Hartley
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Alimentary Canal ◽  
Narrative Review ◽  
Interesting Aspect ◽  
Basic Taste ◽  
Perceptual Independence ◽  
Holistic Perception ◽  
Fat Taste

There are numerous and diverse factors enabling the overconsumption of foods, with the sense of taste being one of these factors. There are four well established basic tastes: sweet, sour, salty, and bitter; all with perceptual independence, salience, and hedonic responses to encourage or discourage consumption. More recently, additional tastes have been added to the basic taste list including umami and fat, but they lack the perceptual independence and salience of the basics. There is also emerging evidence of taste responses to kokumi and carbohydrate. One interesting aspect is the link with the new and emerging tastes to macronutrients, with each macronutrient having two distinct perceptual qualities that, perhaps in combination, provide a holistic perception for each macronutrient: fat has fat taste and mouthfeel; protein has umami and kokumi; carbohydrate has sweet and carbohydrate tastes. These new tastes can be sensed in the oral cavity, but they have more influence post- than pre-ingestion. Umami, fat, kokumi, and carbohydrate tastes have been suggested as an independent category named alimentary. This narrative review will present and discuss evidence for macronutrient sensing throughout the alimentary canal and evidence of how each of the alimentary tastes may influence the consumption of foods.

scholarly journals Melatonin: A Novel Indolamine in Oral Health and Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
V. K. Chava ◽  
K. Sirisha
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Health ◽  
Oral Cavity ◽  
Salivary Glands ◽  
In Vivo Studies ◽  
Systemic Level ◽  
A Cell ◽  
Health And Disease ◽  
Anti Oxidant

This paper attempts to summarise the findings accumulated within the last few years concerning the hormone of darkness “melatonin.” Based on its origin, from the pineal gland until recently it was portrayed exclusively as a hormone. Due to its lipophilic nature, it is accessible to every cell. Thus, in the classic sense it is a cell protector rather than a hormone. Recent studies, by Claustrat et al. (2005), detected few extrapineal sources of melatonin like retina, gastrointestinal tract, and salivary glands. Due to these sources, research by Cutando et al. (2007), is trying to explore the implications of melatonin in the oral cavity, in addition to its physiologic anti-oxidant, immunomodulatory and oncostatic functions at systemic level that may be receptor dependent or independent. Recently, certain in vivo studies by Shimozuma et al. (2011), detected the secretion of melatonin from salivary glands further emphasising its local activity. Thus, within our confines the effects of melatonin in the mouth are reviewed, adding a note on therapeutic potentials of melatonin both systemically and orally.

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