Effects of Qigong practice in quality of life, fatigue, sleep, pain and epigenetic biomarkers in adult women with fibromyalgia

2020 ◽  
Vol 16 (4) ◽  
pp. 285-292
Author(s):  
G.B. Ricciardi ◽  
G. Dorneles ◽  
D. Pochmann ◽  
A. Peres ◽  
V.R. Elsner
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Sleep Quality ◽  
Fibromyalgia Impact Questionnaire ◽  
Good Alternative ◽  
The Body ◽  
Adult Women ◽  
Epigenetic Biomarkers ◽  
At Home

Fibromyalgia is a syndrome mainly diagnosed through patient medical history. These individuals may present symptoms, such as sleeping disorders, migraines, and widespread pain through the musculoskeletal system, resulting in less quality of life. Treatment for fibromyalgia is based on pharmacological and non-pharmacological options. Mind-body practices, such as Baduanjin Qigong, have been described as promising alternatives to better multiple symptoms presented by individuals with the condition. Searching for non-pharmacological alternatives that significantly increase the quality of life of these individuals, this study evaluates the alterations in epigenetic markers in short- and long-term after the practice of Baduanjin Qigong. The participants took part in presential sessions of Baduanjin Qigong twice a week for 8 weeks, as well as being encouraged to practice at home for 4 weeks. The evaluation of the biomarkers was made through the collection of blood samples before the first session, after the sessions in person and after the 4 weeks of practice at home. Fatigue, sleep quality and chronic pain were evaluated before the first sessions and at the end of the process, through the application of self-reported instruments: Fibromyalgia Impact Questionnaire (FIQ), Functional Assessment of Chronic Illness-Fatigue (FACIT), Pittsburgh Sleep Quality Index (PSQI) and Multidimensional Pain Evaluation Scale (EMADOR). As a result, significant improvements were found in quality of life, and in the symptoms of fatigue, sleep disturbance and in chronic pain in some regions of the body. In spite of the clinical-functional improvements, no significant alterations were found in the activity of histone acetyltransferase (HAT) enzymes after the intervention. The practice of Qigong approved to be a good alternative to improve the main symptoms of fibromyalgia in women, without involving modulation of HAT activity.

Sleep disturbance in patients attending specialized chronic pain clinics in Denmark: a longitudinal study examining the relationship between sleep and pain outcomes

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Henrik Bjarke Vaegter ◽  
Mette Terp Høybye ◽  
Frederik Hjorth Bergen ◽  
Christine E. Parsons
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Sleep Quality ◽  
Pain Intensity ◽  
Sleep Disturbances ◽  
Pain Disability ◽  
Pain Clinics ◽  
Pain Outcomes

Abstract Objectives Sleep disturbances are highly prevalent in patients with chronic pain. However, the majority of studies to date examining sleep disturbances in patients with chronic pain have been population-based cross-sectional studies. The aims of this study were to 1) examine the frequency of sleep disturbances in patients referred to two interdisciplinary chronic pain clinics in Denmark, 2) explore associations between sleep disturbances and pain intensity, disability and quality of life at baseline and follow-up, and 3) explore whether changes in sleep quality mediated the relationships between pain outcomes at baseline and pain outcomes at follow-up. Methods We carried out a longitudinal observational study, examining patients enrolled in two chronic pain clinics assessed at baseline (n=2,531) and post-treatment follow-up (n=657). Patients reported on their sleep disturbances using the sleep quality subscale of the Karolinska Sleep Questionnaire (KSQ), their pain intensity using 0–10 numerical rating scales, their pain-related disability using the Pain Disability Index (PDI), and quality of life using the EuroQol-VAS scale. The average time between baseline and follow-up was 207 days (SD=154). Results At baseline, the majority of patients reported frequent sleep disturbances. We found a significant association at baseline between self-reported sleep disturbances and pain intensity, pain-related disability, and quality of life, where greater sleep disturbance was associated with poorer outcomes. At follow-up, patients reported significant improvements across all pain and sleep outcomes. In two mediation models, we showed that changes in sleep disturbances from baseline to follow-up were significantly associated with (i) pain intensity at follow-up, and (ii) pain disability at follow-up. However, baseline pain intensity and disability scores were not associated with changes in sleep disturbances and, we did not find evidence for significant mediation of either pain outcome by changes in sleep disturbances. Conclusions Self-reported sleep disturbances were associated with pain outcomes at baseline and follow-up, with greater sleep disturbances associated with poorer pain outcomes. Changes in sleep quality did not mediate the relationships between baseline and follow-up scores for pain intensity and disability. These findings contribute to a growing body of evidence confirming an association between sleep and chronic pain experience, particularly suggestive of a sleep to pain link. Our data following patients after interdisciplinary treatment suggests that improved sleep is a marker for a better outcome after treatment.

Associations of health-related quality of life with sociodemographic characteristics, health, pain, and lifestyle factors, and motivation for changing lifestyle in adults living with chronic pain: a cross-sectional exploratory study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Svetlana Solgaard Nielsen ◽  
Søren T. Skou ◽  
Anette Enemark Larsen ◽  
Jens Søndergaard ◽  
Jeanette Reffstrup Christensen
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Sleep Quality ◽  
Lifestyle Factors ◽  
Lifestyle Changes ◽  
Poor Sleep ◽  
Related Quality ◽  
Health Related ◽  
Study Population

Abstract Objectives We investigated the associations between health-related quality of life (HRQoL) and health, pain and lifestyle factors, as well as motivation for lifestyle changes, in adults living with chronic pain referred to a Danish pain centre. Methods A total of 144 outpatients completed a questionnaire on HRQoL (EQ-5D-5L), health, pain, lifestyle factors (Body Mass Index [BMI], physical activity, smoking, alcohol, physical fitness, eating, sleep and stress) and motivation for lifestyle changes. We used multiple linear regression analyses to assess associations between HRQoL and the independent variables. Results The participants (age mean 50 years, 81% females) had ≥2 body pain sites (93%), BMI≥25 (64%), sedentary lifestyle (43%) and multiple (n≥2) elevated metabolic risk factors (58%). Most considered lifestyle important for HRQoL (72%) and expressed moderate to very high motivation for changing lifestyle (92%). Poorer HRQoL in the study population was significantly associated with higher pain intensity in the most painful body site (β=−0.316, p=0.001) and very poor sleep quality (β=−0.410, p=0.024). Serious-to-extreme problems in usual activities were associated with significantly poorer health (β=−0.328, p=0.030). Conclusions Adults living with chronic pain participating in this survey had significantly lower self-evaluated HRQoL than the general population. Lower HRQoL was significantly associated with greater pain intensity and poor sleep quality. Serious-to-extreme problems in usual activities, such as work, study, housework, family and leisure, were associated with poorer self-evaluated health. We observed high frequencies of overweight, obesity, sedentary lifestyle, pain in multiple body sites and multiple lifestyle-related risk factors in the study population. Most participants felt motivated for changing lifestyle. Further interventions addressing pain alleviation, sleep quality, prevention of problems in usual activities and promotion of healthy lifestyle, e.g. physical activity and healthy eating, are needed to estimate the effect of a lifestyle-oriented approach on health and quality of life in people living with chronic pain. The results of this study will inform the research project reg. SJ-703, the Danish the Research Ethics Committee for Region Zealand, Denmark.

scholarly journals THE INFLUENCE OF GYMNASTIC EXERCISES IN THE QUALITY OF ADULT WOMEN’S LIFE

2020 ◽  
Vol 13(62) (2) ◽  
pp. 145-152
Author(s):  
C. GUGU-GRAMATOPOL
Keyword(s):  
Quality Of Life ◽  
Comparative Analysis ◽  
Health Status ◽  
Sleep Quality ◽  
Group Practice ◽  
Adult Women ◽  
Contemporary Life ◽  
Sports Activities ◽  
High Effort

The presence of women in all areas of contemporary life is a reality that generates many changes in their lifestyle. In the present study, we aimed to make a comparative analysis in two groups of women. The adults in the first group practice sports activities 2-4 times a week, but have sedentary professions, those in the second group have active professions, with medium to high effort, but do not participate in any sports class, with 3 exceptions. The results obtained show us better values recorded at body indices, and at indices related to health status, sleep quality in women in the second group. Our recommendation for adult women is to adopt a lifestyle with sports activities performed daily, with a medium to high effort to improve their quality of life

scholarly journals Sleep Quality in Older Women: Effects of a Vibration Training Program

2020 ◽  
Vol 10 (23) ◽  
pp. 8391
Author(s):  
María Victoria Palop-Montoro ◽  
Emilio Lozano-Aguilera ◽  
Milagros Arteaga-Checa ◽  
Víctor Serrano-Huete ◽  
Juan Antonio Párraga-Montilla ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Sleep Quality ◽  
Exercise Program ◽  
The Body ◽  
Control Group ◽  
Adult Women ◽  
Quality Of Sleep ◽  
Vibration Training ◽  
Experimental Group

Background: Sleep is an important phenomenon to restore the body, both physically and emotionally, providing a state of balance in the person. It has been proven that adequate sleep at night is one of the main needs of older people in order to maintain an active and healthy life; among other factors, regular physical exercise can improve the quality of sleep. The aim of this research is to evaluate the effects of a physical exercise program supplemented with vibration training on sleep quality and the use of sleep drugs in women over 65 years of age. Methods: Fifty-two independent, physically active adult women were randomised into two groups: a physical exercise program (n = 26, control group) and the same physical exercise program supplemented with vibration training (n = 26, experimental group). The control group performed two weekly sessions of exercise, and the experimental group added another two sessions of vibration training to these two sessions for 12 weeks. Sleep quality was assessed using the Pittsburgh index. Statistical significance was established as p < 0.05. Results: After the intervention, there were significant changes to the quality of sleep (p = 0.001) and hours of sleep (p = 0.002) in the experimental group. The consumption of drugs decreased in this group, although not significantly; however, it did have a moderate effect size (p = 0.058; d = 0.36). The control group, on the other hand, reported significantly worsened sleep quality (p = 0.001) and increased drug use (p = 0.008). Conclusion: Three months of vibration training, as a complement to a conventional physical exercise program, improves sleep quality and reduces the consumption of sleeping pills in women over 65 years of age.

Correlation between the quality of life and sleep quality with the body mass index in Colombian women in climacteric

Maturitas ◽  
2015 ◽  
Vol 81 (1) ◽  
pp. 179
Author(s):  
Alvaro Monterrosa-Castro ◽  
Katherin Portela-Buelvas ◽  
Liezel Ulloque-Caamaño
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Sleep Quality ◽  
Body Mass ◽  
The Body ◽  
Colombian Women

scholarly journals A study protocol for a randomized controlled trial of an anti-inflammatory nutritional intervention in patients with fibromyalgia

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Ana Rita Silva ◽  
Alexandra Bernardo ◽  
Maria Fernanda de Mesquita ◽  
José Vaz Patto ◽  
Pedro Moreira ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Inflammatory Markers ◽  
Short Form ◽  
Fibromyalgia Impact Questionnaire ◽  
Nutritional Intervention ◽  
Disease Assessment ◽  
Control Group ◽  
Anti Inflammatory

Abstract Background This study aims to analyze the effects of a potentially anti-inflammatory nutritional intervention in disease assessment parameters, inflammatory markers, and quality of life of fibromyalgia (FM) patients. Methods A sample of 100 female patients diagnosed with FM, followed up at Portuguese Institute of Rheumatology (IPR) in Lisbon, is being randomly allocated in two groups. Patients in the intervention group are adopting an anti-inflammatory diet, characterized by the exemption of the intake of foods containing gluten, dairy, sugar, and ultra-processed foods, during 3 months. During the first month, a low fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs) diet is implemented, along with the anti-inflammatory diet, followed by the reintroduction of all fruits and vegetables over a consecutive period of 2 months. Patients in the control group are adopting a diet based on general recommendations for healthy eating. The outcomes are pain, fatigue, quality of sleep, quality of life, gastrointestinal symptoms, and inflammation. Before and after the 3 months intervention, and also 1 month after beginning the intervention, the following questionnaires are applied: Revised Fibromyalgia Impact Questionnaire, visual analog pain scale, Brief Pain Inventory,visual analog scale from a list of common gastrointestinal and extraintestinal symptoms in FM, Short Form 36, Fatigue Severity Survey, and Pittsburg Sleep Quality Index. Ultra-sensitive serum C-reactive protein, eritrocyte sedimentation rate, and interleukin-8 are determined. Age, physical activity, anthropometric parameters, and body composition are being collected. Student’s t test will assess the association between the disease evaluation parameters, the inflammatory markers, and the dietary interventions. Discussion The results of this study are expected to determine whether a change in patient nutrition helps to alleviate symptoms, which would optimize medical intervention. Trial registration www.ClinicalTrials.gov NCT04007705. Registered on July 5, 2019.

scholarly journals Health outcomes among adults initiating medical marijuana for chronic pain: A 3-month prospective study incorporating ecological momentary assessment (EMA)

Cannabis ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 69-83
Author(s):  
Yan Wang ◽  
Jennifer Jacques ◽  
Zhigang Li ◽  
Kimberly Sibille ◽  
Robert Cook
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Sleep Quality ◽  
Prospective Study ◽  
Ecological Momentary Assessment ◽  
Medical Cannabis ◽  
Ecological Momentary ◽  
Anxiety Depression ◽  
Momentary Assessment

In response to the need of more rigorous data on medical cannabis and chronic pain, we conducted a 3-month prospective study incorporating ecological momentary assessment (EMA) to examine the effects of medical cannabis on pain, anxiety/depression, sleep, and quality of life. Data were collected from 46 adults (Mean age=55.7±11.9, 52.2% male) newly initiating medical cannabis treatment for chronic pain. Participants completed a baseline survey, EMA for approximately 1 week pre- and up to 3 weeks post- medical cannabis treatment, and a 3-month follow-up survey. The self-reported EMA data (2535 random and 705 daily assessments) indicated significant reductions in momentary pain intensity (b = -16.5, p < .001, 16.5 points reduction on 0-100 visual analog) and anxiety (b = -0.89, p < .05), and significant increase in daily sleep duration (b = 0.34, p < .01) and sleep quality (b = 0.32, p <.001) after participants initiated medical cannabis for a few weeks. At 3 months, self-reported survey data showed significantly lower levels of worst pain (t = -2.38, p < .05), pain interference (t = -3.82, p < .05), and depression (t = -3.43, p < .01), as well as increased sleep duration (t = 3.95, p < .001), sleep quality (t = -3.04, p < .01), and quality of life (t = 4.48, p < .001) compared to baseline. In our sample of primarily middle-aged and older adults with chronic pain, medical cannabis was associated with reduced pain intensity/inference, lower anxiety/depression, and improved sleep and quality of life.

Neuropsychiatric changes during the COVID-19 pandemic in multiple sclerosis patients

2020 ◽  
Vol 78 (9) ◽  
pp. 570-575
Author(s):  
Caner Feyzi DEMIR ◽  
Furkan BILEK ◽  
Ferhat BALGETIR
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Sleep Quality ◽  
The Body ◽  
Assessment Tools ◽  
Survey Study ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Multiple Sclerosis Patients

ABSTRACT Background: This study reported on a variety of psychological reactions related to anxiety, sleep quality, depression, fatigue, and quality of life in individuals with multiple sclerosis (MS), related to the Covid-19 quarantine experience. Objective: The aim of this study was to investigate the neuropsychiatric effects of the COVID-19 pandemic in MS patients and to analyze the risk factors contributing to psychological stress. Methods: The study was designed as a prospective, cross-sectional survey study. Multiple assessment tools that are used in neurological practice, including Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Fatigue Impact Scale (FIS), Pittsburgh Sleep Quality Index (PSQI), and Multiple Sclerosis Quality of Life-54 (MSQOL-54) were administered prospectively both during the early and the peak stages of COVID-19 outbreak (ESO and PSO, respectively). The survey forms were designed using SurveyMonkey and the participants were participating in the survey via a web link and QR code. Results: Fifty patients were included in the study. BDI scores, PSQI and FSI measurements, cognitive and social subscale scores and total FIS score, MSQOL-54 measurements, physical and mental subscale scores, and total MSQOL-54 score at PSO were significantly different than those at ESO. The body mass index values of the patients increased significantly at PSO compared to those measured at ESO. Conclusions: The results provide a basis for the development of psychological interventions that could minimize the prevalence of sleep disorders and depression and could improve patients’ quality of life during the outbreak.

scholarly journals Cardiovascular Autonomic Control, Sleep and Health Related Quality of Life in Systemic Sclerosis

2021 ◽  
Vol 18 (5) ◽  
pp. 2276
Author(s):  
Angelica Carandina ◽  
Chiara Bellocchi ◽  
Gabriel Dias Rodrigues ◽  
Lorenzo Beretta ◽  
Nicola Montano ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Systemic Sclerosis ◽  
Sleep Quality ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Cardiovascular Autonomic Control ◽  
Hrv Analysis

Chronic pain and dysautonomic symptoms deteriorate Systemic sclerosis (SSc) patients’ health-related quality of life with serious repercussions on social life and even on sleep. Heart Rate Variability (HRV) analysis can identify cardiovascular autonomic control impairment in subclinical condition. The aim of the present observational cross-sectional study was to assess the relationship between dysautonomic symptoms, quality of life status and cardiovascular autonomic profile. ECG and respiration were recorded at rest in 20 SSc patients. HRV analysis was performed using two different approaches: Linear spectral analysis and non-linear symbolic analysis. Pain was evaluated using the Numeric Rating Scale (NRS) and 3 questionnaires were administered for the evaluation of sleep quality (PSQI), mood tone (PHQ-9) and disability (HAQ). We found that sleep impairment was related to sympathetic predominance at rest measured as low-frequency/high-frequency ratio (LF/HF) (r = 0.48 and p = 0.033); poorer sleep quality was related to higher pain values (r = 0.48 and p = 0.034) and depressive symptoms (r = 0.82 and p < 0.01); higher pain scores were related to higher cardiovascular vagal modulation and higher disability indexes (r = 0.47 and p = 0.038 & r = 0.55 and p = 0.012, respectively). In conclusion dysautonomia and chronic pain showed a severe impact on sleep quality and disability with a consequent worsening of depressive symptom in our cohort of SSc patients.

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