scholarly journals Fatty Acid Profile, α-Tocopherol Content and Total Antioxidant Activity of Oil Extracted from Nigella sativa Seeds

2009 ◽  
Vol 5 (4) ◽  
pp. 244-250 ◽  
Author(s):  
Ghanya Al-Naqeeb ◽  
Maznah Ismail ◽  
Adel S. Al-Zuba
2009 ◽  
Vol 103 (2) ◽  
pp. 256-265 ◽  
Author(s):  
Patrícia B. Botelho ◽  
Cyntia O. Fioratti ◽  
Dulcinéia S. P. Abdalla ◽  
Marcelo C. Bertolami ◽  
Inar A. Castro

Oxidative stress is a physiological condition that is associated with atherosclerosis, and it can be influenced by diet. Our objective was to group fifty-seven individuals with dyslipidaemia controlled by statins according to four oxidative biomarkers, and to evaluate the diet pattern and blood biochemistry differences between these groups. Blood samples were collected and the following parameters were evaluated: diet intake; plasma fatty acids; lipoprotein concentration; glucose; oxidised LDL (oxLDL); malondialdehyde (MDA); total antioxidant activity by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing ability power assays. Individuals were separated into five groups by cluster analysis. All groups showed a difference with respect to at least one of the four oxidative stress biomarkers. The separation of individuals in the first axis was based upon their total antioxidant activity. Clusters located on the right side showed higher total antioxidant activity, higher myristic fatty acid and lower arachidonic fatty acid proportions than clusters located on the left side. A negative correlation was observed between DPPH and the peroxidability index. The second axis showed differences in oxidation status as measured by MDA and oxLDL concentrations. Clusters located on the upper side showed higher oxidative status and lower HDL cholesterol concentration than clusters located on the lower side. There were no differences in diet among the five clusters. Therefore, fatty acid synthesis and HDL cholesterol concentration seem to exert a more significant effect on the oxidative conditions of the individuals with dyslipidaemia controlled by statins than does their food intake.


Author(s):  
Jenifer Panneer ◽  
C. P. Balakrishnan

Evaluation of various organic solvent extracts of marine red algae Gracilaria fergusonii used for priliminary screening of phytoconstituents and in-vitro total antioxidant activity. The phytochemical screening was carried out by cooling percolation extraction using different solvents like acetone, ethanol, chloroform, petroleum ether, benzene, methanol and water. The standard regression of alpha tocopherol gives linear regression [y=0.0004x + 0.0807 (R2= 0.9814)] obtained and used to calculate the standard and the total antioxidant activity are expressed as equivalents of vitamin E (µg g-1). The present study reavealed that most of the phytochemicals like alkaloids,  coumarin, flavonoids, phenol, quinons, steroids, saponin, tannins, glycosides, amino acid, sugar, protein and fatty acid were present in the dried algal sample. The total antioxidant activity was done by phosphomolybdate method using α- tocopherol as standard. Keywords: Gracilaria fergusonii, phytoconstituents, antioxidant, α-tocopherol


Author(s):  
A. R. Mubinov ◽  
E. V. Avdeeva ◽  
V. A. Kurkin ◽  
G. M. Latypova ◽  
R. R. Farkhutdinov ◽  
...  

2007 ◽  
Vol 33 (3) ◽  
pp. 375-376 ◽  
Author(s):  
M. F. Borisenkov ◽  
L. A. Erunova ◽  
E. M. Lyuseva ◽  
N. V. Pozdeeva

2019 ◽  
Vol 59 (7) ◽  
pp. 134-141
Author(s):  
Anatoly A. Lapin ◽  
◽  
Irek G. Garifullin ◽  
Valery N. Zelenkov ◽  
◽  
...  

The article presents the results of biochemical studies of the total antioxidant activity of the hepatoprotective collection of plant origin and its individual components, which show that it consists of birch leaves (Betulae folia), tansy flowers (Tanaceti flores), phytohepatol No. 2 (choleretic collection No. 2) and individual its components have pronounced antioxidant activity. More antioxidant activity founded in tansy and true hepatoprotective collection. Comparative tests of the flowers of meadowsweet, with the highest antioxidant activity, showed the promise of their use in the collections of medicinal plants as effective natural metabolic regulators. The total antioxidant activity of the water extract collection at 13.56% rel. exceeded the calculated value obtained by summing the activities of the individual components of the collection, which indicates the presence of synergism in their action, which may be of value for use in the treatment and prevention of liver diseases. When all components of the drug collection are finished, the indicator increases by 11-24 % rel., which indicates the thermal stability of the antioxidant substances that make up their composition. In the oxidation of aqueous extracts of the components of hepatoprotective collection with hydrogen peroxide, the most stable were antioxidants of birch leaves. It was found that collection only at a ratio of 7.7 g per liter of water shows synergism (15 % rel.), and the rest of all the samples we tested are antagonistic. The detected increase in the antioxidant activity of the new collection compared with the effects of its individual components allows us to consider it as a promising dosage form for use in the treatment and prevention of liver diseases.


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