IMPROVE ON PERFORMANCE OF INDIRECT CALORIMETRY FOR SMALL PRETERM INFANTS

2001 ◽  
Vol 13 (03) ◽  
pp. 109-115 ◽  
Author(s):  
SHIH-CHING LIN ◽  
CHING-HSING LUO ◽  
TSU-FUH YEH
Keyword(s):  
Oxygen Consumption ◽  
Energy Consumption ◽  
Clinical Research ◽  
Preterm Infants ◽  
Indirect Calorimetry ◽  
Carbon Dioxide Production ◽  
Laboratory Evaluation ◽  
Low Birth Weight Infants ◽  
Accuracy And Precision ◽  
Improved Performance

An indirect calorimetry system of measuring oxygen consumption and carbon dioxide production has been frequently used for preterm infants. The energy consumption and metabolic measurements are based on flow-through technology. The noninvasive measurement feature of the indirect calorimeter is widely used in pediatric clinical research. However, the indirect calorimeter has several limitations for small preterm infants, particularly the ill infant weighing < 1.0 kg. In this paper, we propose some technologies and methodologies to improve the performance of the indirect calorimetry. According to these technologies and methodologies, we redesign the indirect calorimeter proposed in our pervious study. The laboratory evaluation at the different alcohol combustion rates and several exhaust flow rates is used to survey the improved performance. As the results, the accuracy and precision is enhanced by these methods and the lowest oxygen consumption rate, 4.35 ml/min, fits for baby weight of 0.66 kg. It is demonstrated that the performances of new indirect calorimetry are substantially improved. It can be applied to calculate the energy consumption and metabolic rate for low-birth-weight infants in clinical research.

scholarly journals The Accuracy and Precision of an Open-Circuit System To Measure Oxygen Consumption and Carbon Dioxide Production in Neonates

1987 ◽  
Vol 21 (1) ◽  
pp. 58-65 ◽  
Author(s):  
Keith H Marks ◽  
Patricia Coen ◽  
James R Kerrigan ◽  
Nick A Francalancia ◽  
Elizabeth E Nardis ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Carbon Dioxide Production ◽  
Open Circuit ◽  
Accuracy And Precision ◽  
Measure Oxygen Consumption

scholarly journals A Systematic Review and Meta-Analysis of Human Milk Feeding and Short-Term Growth in Preterm and Very Low Birth Weight Infants

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2089
Author(s):  
Machiko Suganuma ◽  
Alice R. Rumbold ◽  
Jacqueline Miller ◽  
Yan Fong Chong ◽  
Carmel T. Collins
Keyword(s):  
Systematic Review ◽  
Birth Weight ◽  
Human Milk ◽  
Preterm Infants ◽  
Very Low Birth Weight ◽  
Meta Analysis ◽  
Poor Quality ◽  
Low Birth Weight Infants ◽  
Preterm Formula ◽  
Meta Analyses

Human milk (HM) is the gold standard for feeding infants but has been associated with slower growth in preterm infants compared with preterm formula. This systematic review and meta-analysis summarises the post-1990 literature to examine the effect of HM feeding on growth during the neonatal admission of preterm infants with birth weight ≤1500 g and/or born ≤28 weeks’ gestation. Medline, PubMed, CINAHL, and Scopus were searched, and comparisons were grouped as exclusive human milk (EHM) vs. exclusive preterm formula (EPTF), any HM vs. EPTF, and higher vs. lower doses of HM. We selected studies that used fortified HM and compared that with a PTF; studies comparing unfortified HM and term formula were excluded. Experimental and observational studies were pooled separately. The GRADE system was used to evaluate risk of bias and certainty of evidence. Forty-four studies were included with 37 (n = 9963 infants) included in the meta-analyses. In general, due to poor quality studies, evidence of the effect of any HM feeds or higher versus lower doses of HM was inconclusive. There was a possible effect that lower doses of HM compared with higher doses of HM improved weight gain during the hospital admission, and separately, a possible effect of increased head circumference growth in infants fed EPTF vs. any HM. The clinical significance of this is unclear. There was insufficient evidence to determine the effects of an exclusive HM diet on any outcomes.

scholarly journals ANALYSIS OF THE DIFFERENCES BETWEEN THE PRESCRIBED AND THE ADMINISTERED DIET TO PRETERM INFANTS USING AN ELECTRONIC TOO

2019 ◽  
Vol 37 (4) ◽  
pp. 472-478 ◽  
Author(s):  
Olivia Araújo Zin ◽  
Fernanda Valente Mendes Soares ◽  
Andrea Dunshee de Abranches ◽  
Ana Carolina Carioca da Costa ◽  
Letícia Duarte Villela ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Gestational Age ◽  
Very Low Birth Weight ◽  
Body Weight Gain ◽  
Nutritional Deficiencies ◽  
Percentage Error ◽  
Electronic Instrument ◽  
Health Providers ◽  
Low Birth Weight Infants

ABSTRACT Objective: To create an electronic instrument in order to analyze the adequacy of the preterm infants’ nutritional therapy, checking the difference between the prescribed and the administered diet. Methods: A prospective and observational study on newborns with birthweight ≤1,500g and/or gestational age ≤32 weeks, without congenital malformations. The electronic instrument was developed based on Microsoft Excel 2010 spreadsheets and aimed at automatically calculating body weight gain, calories and macronutrients received daily by each patient from parenteral nutrition, intravenous hydration and enteral feedings. The weekly means of each nutrient were used to compare the prescribed and administered diets. Results: To evaluate the instrument, 60 newborns with a birth weight of 1,289±305 g and a gestational age of 30±2 weeks were included. Of them, 9.6% had restricted growth at birth and 55% at discharge. The median length of stay was 45±17 days. There were significant differences between prescribed and administered diet for all of the macronutrients and for total calories in the first three weeks. The lipid was the macronutrient with the greatest percentage error in the first week of life. Conclusions: The use of a computational routine was important to verify differences between the prescribed and the administered diet. This analysis is necessary to minimize calculation errors and to speed up health providers’ decisions about the nutritional approach, which can contribute to patients’ safety and to good nutritional practice. Very low birth weight infants are extremely vulnerable to nutritional deficiencies and any reduction in macronutrients they receive may be harmful to achieve satisfactory growth.

Metabolism during normoxia, hyperoxia, and recovery in newborn rats

1992 ◽  
Vol 70 (3) ◽  
pp. 408-411 ◽  
Author(s):  
Peter B. Frappell ◽  
Andrea Dotta ◽  
Jacopo P. Mortola
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Metabolic Rate ◽  
Carbon Dioxide Production ◽  
Oxygen Availability ◽  
Aerobic Metabolism ◽  
Newborn Rats ◽  
Ambient Temperatures ◽  
Positive Effects

Aerobic metabolism (oxygen consumption, [Formula: see text], and carbon dioxide production, [Formula: see text]) has been measured in newborn rats at 2 days of age during normoxia, 30 min of hyperoxia (100% O2) and an additional 30 min of recovery in normoxia at ambient temperatures of 35 °C (thermoneutrality) or 30 °C. In normoxia, at 30 °C [Formula: see text] was higher than at 35 °C. With hyperoxia, [Formula: see text] increased in all cases, but more so at 30 °C (+20%) than at 35 °C (+9%). Upon return to normoxia, metabolism readily returned to the prehyperoxic value. The results support the concept that the normoxic metabolic rate of the newborn can be limited by the availability of oxygen. At temperatures below thermoneutrality the higher metabolic needs aggravate the limitation in oxygen availability, and the positive effects of hyperoxia on [Formula: see text] are therefore more apparent.Key words: neonatal respiration, oxygen consumption, thermoregulation.

Effect of Caffeine on Oxygen Consumption and Metabolic Rate in Very Low Birth Weight Infants With Idiopathic Apnea

PEDIATRICS ◽  
2001 ◽  
Vol 107 (4) ◽  
pp. 660-663 ◽  
Author(s):  
Jacqueline Bauer ◽  
Kathrin Maier ◽  
Otwin Linderkamp ◽  
Roland Hentschel
Keyword(s):  
Oxygen Consumption ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Metabolic Rate ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants

GASEOUS METABOLISM IN PREMATURE INFANTS AT 32-34°C AMBIENT TEMPERATURE

PEDIATRICS ◽  
1964 ◽  
Vol 33 (1) ◽  
pp. 75-82
Author(s):  
Forrest H. Adams ◽  
Tetsuro Fujiwara ◽  
Robert Spears ◽  
Joan Hodgman
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Premature Infants ◽  
Rectal Temperature ◽  
Respiratory Quotient ◽  
Carbon Dioxide Production ◽  
Open Circuit ◽  
Co2 Production ◽  
O2 Consumption ◽  
Rate Of Increase

Thirty-four measurements of oxygen consumption, carbon dioxide production, respiratory quotient, and rectal temperature were made on 22 premature infants with ages ranging from 2½ hours to 18 days. The studies were conducted at 32-34°C utilizing an open circuit apparatus and a specially designed climatized chamber. Oxygen consumption and carbon dioxide production were lowest in the first 12 hours and increased thereafter. The rate of increase in O2 consumption was greater than that of CO2 production, with a consequent fall in respiratory quotient during the first 76 hours of life. A reverse relation of O2 consumption and CO2 production was found following the 4th day of life with a consequent rise in respiratory quotient. There was a close correlation between O2 consumption and rectal temperature regardless of age. A respiratory quotient below the value of 0.707 for fat metabolism was observed in 7 premature infants with ages ranging from 24 to 76 hours.

Reduction of Oxygen Consumption, Insensible Water Loss, and Radiant Heat Demand with Use of a Plastic Blanket for Low-Birth-Weight Infants Under Radiant Warmers

PEDIATRICS ◽  
1984 ◽  
Vol 74 (6) ◽  
pp. 1022-1028
Author(s):  
Stephen Baumgart
Keyword(s):  
Oxygen Consumption ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Water Loss ◽  
Very Low Birth Weight ◽  
Radiant Heat ◽  
Low Birth Weight Infants ◽  
Heat Demand ◽  
Radiant Heater ◽  
Radiant Warmer

Eight very low-birth-weight premature infants (mean birth weight 1.11 ± 0.05 [SEM] kg, mean gestation 30 ± 1 weeks, and mean age 9 ± 2 days) were studied under servocontrolled radiant warmers with and without a loosely fitted, transparent, and flexible Saran plastic blanket. Metabolic rate was significantly less in all infants when covered by the blanket (oxygen consumption was 7.99 ± 1.13 mL/kg/min v 9.00 ± 1.10 mL/kg/min uncovered, P &lt; .001). There were also significant reductions in insensible water loss (1.86 ± 0.18 v 1.25 ± 0.20 mL/kg/h, P &lt; .01) and in heat demand from the radiant warmer (14.3 ± 1.3 v 9.9 ± 1.4 mW/cm2, P &lt; .001) when infants were nursed under the blanket compared with the control condition, respectively. Covering the critically ill, very low-birth-weight infant nursed under a radiant heater with a thin, transparent layer of Saran is beneficial in reducing oxygen consumption, insensible water loss, and the need for exposure to high levels of radiant heat. Further investigation to confirm the benefits and possible complications of plastic blankets should be conducted before routine use can be recommended.

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