Comparative Inspection of Terbufos in Blood from Head Skin by GC-MS

2014 ◽  
Vol 496-500 ◽  
pp. 524-527
Author(s):  
Jiang Ping Xu ◽  
Dai Qin Tao
Keyword(s):  
Retention Time ◽  
High Sensitivity ◽  
Detection Sensitivity ◽  
Column Efficiency ◽  
Mass Fragment ◽  
B Method ◽  
Poisoning Case ◽  
Fragment Peak ◽  
Condition B

This paper selects a typical poisoning case of pesticide topical on head. Technicians extracted the victim's blood, vomit and swabs, and toxicant tests were under Condition-A and Condition-B. Terbufos ingredients were detected from the blood and swabs, but not found in vomit. Compared Condition-B to Condition-A: it has increased the column efficiency and improved the separation of Terbufos, thereby improving the detection sensitivity of Terbufos. The Condition-B method selects more than one mass fragment peak for scanning, which is of high sensitivity and less impurities interference. While using Terbufos standards for retention time comparison, the results are accurate and reliable.

scholarly journals High Sensitivity Continuous Monitoring of Chloroform Gas by Using Wavelength Modulation Photoacoustic Spectroscopy in the Near-Infrared Range

2021 ◽  
Vol 11 (15) ◽  
pp. 6992
Author(s):  
Tie Zhang ◽  
Yuxin Xing ◽  
Gaoxuan Wang ◽  
Sailing He
Keyword(s):  
Photoacoustic Spectroscopy ◽  
Continuous Monitoring ◽  
Near Infrared ◽  
Resonant Cavity ◽  
High Sensitivity ◽  
Industrial Applications ◽  
Detection Sensitivity ◽  
Infrared Range ◽  
Wavelength Modulation ◽  
Linear Coefficient

An optical system for gaseous chloroform (CHCl3) detection based on wavelength modulation photoacoustic spectroscopy (WMPAS) is proposed for the first time by using a distributed feedback (DFB) laser with a center wavelength of 1683 nm where chloroform has strong and complex absorption peaks. The WMPAS sensor developed possesses the advantages of having a simple structure, high-sensitivity, and direct measurement. A resonant cavity made of stainless steel with a resonant frequency of 6390 Hz was utilized, and eight microphones were located at the middle of the resonator at uniform intervals to collect the sound signal. All of the devices were integrated into an instrument box for practical applications. The performance of the WMPAS sensor was experimentally demonstrated with the measurement of different concentrations of chloroform from 63 to 625 ppm. A linear coefficient R2 of 0.999 and a detection sensitivity of 0.28 ppm with a time period of 20 s were achieved at room temperature (around 20 °C) and atmosphere pressure. Long-time continuous monitoring for a fixed concentration of chloroform gas was carried out to demonstrate the excellent stability of the system. The performance of the system shows great practical value for the detection of chloroform gas in industrial applications.

scholarly journals High-sensitivity tunneling magneto-resistive micro-gyroscope with immunity to external magnetic interference

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Li Jin ◽  
Shi-Yang Qin ◽  
Rui Zhang ◽  
Meng-Wei Li
Keyword(s):  
Bridge Circuit ◽  
High Sensitivity ◽  
Micro Electro Mechanical System ◽  
Detection Sensitivity ◽  
Force Detection ◽  
Mems Gyroscope ◽  
Mems Gyroscopes ◽  
Potential Applications ◽  
Magneto Resistance ◽  
Total Sensitivity

Abstract Micro-electro-mechanical system (MEMS) gyroscopes have numerous potential applications including guidance, robotics, tactical-grade navigation, and automotive applications fields. The methods with ability of the weak Coriolis force detection are critical for MEMS gyroscopes. In this paper, we presented a design of MEMS gyroscope based on the tunneling magneto-resistance effect with higher detection sensitivity. Of all these designed parameters, the structural, magnetic field, and magneto-resistance sensitivity values reach to 21.6 nm/°/s, 0.0023 Oe/nm, and 29.5 mV/Oe, thus, with total sensitivity of 1.47 mV/°/s. Multi-bridge circuit method is employed to suppress external magnetic interference and avoid the integration error of the TMR devices effectively. The proposed tunneling magneto-resistive micro-gyroscope shows a possibility to make an inertial grade MEMS gyroscope in the future.

scholarly journals Standardization of an LNA-based TaqMan assay qPCR analysis for Aspiculuris tetraptera DNA in mouse faeces

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Keishiro Isayama ◽  
Kenji Watanabe ◽  
Mariko Okamoto ◽  
Tomoaki Murata ◽  
Yoichi Mizukami
Keyword(s):  
Genomic Dna ◽  
High Sensitivity ◽  
Locked Nucleic Acid ◽  
Detection Sensitivity ◽  
Taqman Assay ◽  
Highly Sensitive ◽  
Aspiculuris Tetraptera ◽  
Pcr Techniques ◽  
Quantitative Pcr Assay ◽  
Direct Microscopic Observation

Abstract Background Aspiculuris tetraptera, as a parasitic pinworm, is most frequently detected in laboratory mice, and transmission is mediated by the eggs contained in the faeces of infected mice. A highly sensitive and quantitative faeces-based diagnostic tool would be useful for the early detection of A. tetraptera to inhibit the expansion of infection. In this study, we developed a quantitative assay that exhibits high sensitivity in detecting A. tetraptera in faeces using PCR techniques. Results Endpoint PCR demonstrated the detection of A. tetraptera DNA in 0.5 ng genomic DNA extracted from the faeces of infected mice. To quantitatively detect the small amount of A. tetraptera DNA, locked nucleic acid (LNA)-based primers and LNA-based TaqMan probes were used for the quantitative PCR assay (qPCR). The combination of LNA-based DNA increased detection sensitivity by more than 100-fold compared to using normal oligo DNAs. The copy number of the A. tetraptera DNA detected was positively related to the infected faeces-derived genomic DNA with a simple linearity regression in the range of 20 pg to 15 ng of the genomic DNA. To more conveniently detect infection using faeces, the LNA-based TaqMan assay was applied to the crude fraction of the faeces without DNA purification. An assay using ethanol precipitation of the faeces yielded results consistent with those of direct microscopic observation. Conclusion The LNA-TaqMan assay developed in this study quantitatively detects A. tetraptera infection in mouse faeces.

Simulation of Gold Nanoparticles Aggravating MEMS Cantilever Optical Static Detection Biochip

2013 ◽  
Vol 694-697 ◽  
pp. 966-970 ◽  
Author(s):  
Yue Tao Ge ◽  
Xiao Tong Yin
Keyword(s):  
Gold Nanoparticles ◽  
Low Cost ◽  
Mechanical Systems ◽  
Side Wall ◽  
High Sensitivity ◽  
Detection Sensitivity ◽  
Gene Detection ◽  
Micro Electro Mechanical Systems ◽  
Target Dna ◽  
Static Detection

A kind of gene detection biochip model based on biological micro electro mechanical systems (BioMEMS) technology and micro optical electro mechanical systems (MOEMS) technology is designed and simulated. In order to detect whether there are nucleic acid components in the testing samples, the biochip in this study issues horizontal light by laser, then receives and reads the deformation signals of MEMS cantilever by optical detector. The MEMS optical reflecting system can amplify MEMS cantilever deformation signal 22 times by micro reflectors which are set on the side wall of the cantilever free end. In order to improve optical detection sensitivity, gold nanoparticles (GNPs) which are combined with hybridization information is taken to aggravate MEMS cantilever, and employ Au - S chemical bond of GNPs and dithiol HS(CH2)6SH to combine and fix DNA probe, and then employ target DNA which is marked with biotin to combine GNPs by Biotin - Streptavidin combining. The simulation results show that this biochip can detect biological samples fast, high throughput, low cost, high sensitivity and reliably.

Novel electrochemiluminescent materials for sensor applications

2014 ◽  
Vol 174 ◽  
pp. 357-367 ◽  
Author(s):  
Lynn Dennany ◽  
Zahera Mohsan ◽  
Alexander L. Kanibolotsky ◽  
Peter J. Skabara
Keyword(s):  
Redox Reactions ◽  
Limit Of Detection ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Radical Cations ◽  
Detection Sensitivity ◽  
Sensor Development ◽  
Sensor Applications ◽  
Sensor Devices ◽  
The Impact

Electrochemiluminescence (ECL) uses redox reactions to generate light at an electrode surface, and is gaining increasing attention for biosensor development due to its high sensitivity and excellent signal-to-noise ratio. ECL studies of monodisperse oligofluorene–truxenes (T4 series) have been reported previously, showing the production of stable radical cations and radical anions, generating blue ECL. The compound in this study differs from the original structures, in that there are 2,1,3-benzothiadazole (BT) units inserted between the first and second fluorene units of the quarterfluorenyl arms. It was therefore anticipated that the incorporation of these highly luminescent and ECL-active compounds into sensor development would lead to significant decreases in detection limits. In this contribution, we report on the impact of incorporating these novel complexes into sensor devices on the ECL efficiency, as well as the ability of these to improve the detection sensitivity and decrease the limit of detection using the reagent-free detection of model analytes. The real world impact of these compounds is elucidated through the comparison with more standard ECL materials such as ruthenium-based compounds. The potential for multiple applications is to be examined within this contribution.

Far-ultraviolet Ionospheric Photometer

2020 ◽  
Author(s):  
Ruyi Peng ◽  
Liping Fu
Keyword(s):  
High Sensitivity ◽  
Detection Sensitivity ◽  
Space Environment ◽  
Physical Parameters ◽  
Optical Remote Sensing ◽  
Electronic Density ◽  
Radio Communications ◽  
Important Means ◽  
Far Ultraviolet ◽  
The Impact

<p>As a space-based optical remote sensing method, Far-ultraviolet Ionospheric Photometer with small size, low power consumption, high sensitivity is an important means to detect physical parameters of the ionosphere. Using the Far-ultraviolet Ionospheric Photometer to detect the intensity of ionospheric 135.6nm night airglow can obtain the ionospheric TEC, F2 layer peak electronic density(NmF2), which can be used to study the information on changes in ionospheric space environment,and the impact of the ionosphere on the radio communications, etc.; The ionospheric 135.6nm day airglow and the LBH radiation radiance can be used to obtain the ionospheric O / N2 ratio information, which can be used to study the space weather events and monitor the electromagnetic environment changes in the Earth's space. The FY3-D Ionospheric Photometer(IPM), launched on November 15, 2017, has a detection sensitivity which is greater than 150 counts / s / Rayleigh and a spatial field of view of 1.6 × 3.5 ° with high horizontal spatial resolution that will help to achieve the fine detection of the ionosphere. This report will analyze the FY3-D IPM detection results.At the same time,the report will introduce our research team’s work on the development and application of other payloads in the far ultraviolet band</p>

Quantitative measurement of OH radical using Faraday rotation spectroscopy at 2.8 µm

2020 ◽  
Author(s):  
Weixiong Zhao ◽  
Bo Fang ◽  
Nana Wei ◽  
Nana Yang ◽  
Weijun Zhang ◽  
...  
Keyword(s):  
Faraday Rotation ◽  
Atmospheric Chemistry ◽  
Quantitative Measurement ◽  
High Sensitivity ◽  
Vital Role ◽  
Detection Sensitivity ◽  
Detection Methods ◽  
Paramagnetic Species ◽  
Oh Radicals ◽  
Chemistry Research

<p>Hydroxyl (OH) radicals play a vital role in the degradation of trace gases and pollutants in the troposphere and in controlling the atmospheric oxidation capacity. Due to its short lifetime and low concentration, interference-free high sensitivity in situ OH monitoring by laser spectroscopy represents a challenge. In this presentation, we will report the development of Faraday rotation spectroscopy (FRS) instruments operating at 2.8 µm for quantitative measurement of OH concentrations in an atmospheric simulation chamber and the total atmospheric OH reactivity (k’<sub>OH</sub>). The Q (1.5) double lines (<sup>2</sup>Π<sub>3/2</sub> (ν=1<-0)) at 3568 cm<sup>-1</sup> were selected for the detection. Different detection methods have been studied. The FRS technology relies on the particular magneto-optic effect observed for paramagnetic species (including most radicals and some compounds with unpaired electrons), which can significantly reduce excess laser noise and makes it capable of enhancing the detection sensitivity and mitigation of spectral interferences from diamagnetic species in the atmosphere. With the use of a multipass enhanced FRS, a detection limit of 3.2 × 10<sup>6</sup> OH/cm<sup>3</sup> (2σ, 4s) was achieved with an absorption path length of 108 m. We demonstrated that FRS method provides a unique method for atmospheric chemistry research.</p>

Study of High Sensitivity Sensor Based on the Principle of Photoionization

2012 ◽  
Vol 503 ◽  
pp. 188-193 ◽  
Author(s):  
Kun Wang Niu ◽  
Ting Liang ◽  
Fang Yang ◽  
Qing Meng ◽  
Kai Wang ◽  
...  
Keyword(s):  
Bias Voltage ◽  
Signal Intensity ◽  
Ionization Chamber ◽  
Detection Efficiency ◽  
High Sensitivity ◽  
Signal Strength ◽  
Detection Sensitivity ◽  
Weak Signal Detection ◽  
The Relationship

The quality of designing structure and properties of sensor photoionization room，directly determines its weak signal detection sensitivity detection and effecting ionization chamber detection efficiency .The paper experiments on four factors of affect the sensitivity of sensor. The results show that: the signal intensity proportional to the area of the ionization chamber; signal intensity goes up with the increase of bias voltage, and with bias voltage into a square the relationship; signal strength was first increased and then decreased with the growth of the distance between electrodes; signal strength was first increased and then decreased. With the growth of light-driven power.

scholarly journals Lateral Flow Immunoassay with Quantum-Dot-Embedded Silica Nanoparticles for Prostate-Specific Antigen Detection

Nanomaterials ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 33
Author(s):  
Sungje Bock ◽  
Hyung-Mo Kim ◽  
Jaehi Kim ◽  
Jaehyun An ◽  
Yun-Sik Choi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Silica Nanoparticles ◽  
Prostate Specific Antigen ◽  
False Negative ◽  
Specific Antigen ◽  
Calf Serum ◽  
High Sensitivity ◽  
Lateral Flow ◽  
Detection Sensitivity ◽  
Lateral Flow Immunoassay

Prostate cancer can be detected early by testing the presence of prostate-specific antigen (PSA) in the blood. Lateral flow immunoassay (LFIA) has been used because it is cost effective and easy to use and also has a rapid sample-to-answer process. Quantum dots (QDs) with very bright fluorescence have been previously used to improve the detection sensitivity of LFIAs. In the current study, a highly sensitive LFIA kit was devised using QD-embedded silica nanoparticles. In the present study, only a smartphone and a computer software program, ImageJ, were used, because the developed system had high sensitivity by using very bright nanoprobes. The limit of PSA detection of the developed LFIA system was 0.138 ng/mL. The area under the curve of this system was calculated as 0.852. The system did not show any false-negative result when 47 human serum samples were analyzed; it only detected PSA and did not detect alpha-fetoprotein and newborn calf serum in the samples. Additionally, fluorescence was maintained on the strip for 10 d after the test. With its high sensitivity and convenience, the devised LFIA kit can be used for the diagnosis of prostate cancer.

scholarly journals Method for Creating Networks between Vehicles to Monitor Vehicle Condition

2017 ◽  
Vol 58 (4) ◽  
pp. 285-291
Author(s):  
Satoko RYUO ◽  
Nagateru IWASAWA ◽  
Tomoki KAWAMURA ◽  
Akio HADA ◽  
Kunihiro KAWASAKI
Keyword(s):  
B Method ◽  
Condition B
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