Effect of Coloring Agents on Starch Properties: In Powder and Paste Form

2010 ◽  
Vol 93-94 ◽  
pp. 173-176
Author(s):  
S. Kongmuang ◽  
N. Phakdisirivichai ◽  
N. Detwattanadet ◽  
N. Samma ◽  
D. Anurakchanaphon ◽  
...  

The aim of this study was focusing on the excipients interaction especially between coloring agents and diluents. There were two coloring agents with different charges ; methylene blue(M) showing positive charge while amaranth(A) giving negative charge but all having same concentration of 0.1% w/w in each mixing batch. There are five types of starch using as diluents; arrowroot starch (W), rice starch (R), cassava starch (S), corn starch (C) and lesser yam starch (l). The physical properties of starch powder and paste (5%w/v) were evaluated as angle of repose and viscosity respectively. While the concentration of both coloring agents were determined by either UV spectroscopy or eye observation. The storage conditions of all samples were kept in both light and dark area for 7 weeks. It was found in powder form that C gave the most stable of M while R gave the worst for m in both light and dark condition. M showed less influences on flow properties of starches than a in a powder state. The flow of C with M gave the best results. The W paste was shown to be the most stable physical properties. M was suitable for S paste in a dark condition. While A was suitable for C, R and W paste in a light condition. The charges of coloring agents might not be a major influence on some physical properties of starch in both powder and paste form.

2016 ◽  
Vol 14 (2) ◽  
pp. 147-151
Author(s):  
Bakre Lateef Gbenga ◽  
Yusuf Taiwo

This study evaluates the effect of storage conditions on some pharmaceutical parameters of powders (paracetamol, corn starch, tragacanth and polyvinyl pyrrolidone) and tablets (paracetamol, metronidazole and vitamin C). For powdered samples, angle of repose, bulk and tapped densities were determined while the tablets were evaluated for hardness, friability and disintegration before and after exposure to various humidity conditions, radiations from telecommunication mast and sunlight at intervals of 24 hrs & 1, 2, 4 and 8 weeks. The results showed a decrease in the angle of repose for paracetamol, corn starch, polyvinyl pyrollidone and tragacanth powders on exposure to sunlight. There was no significant (p>0.05) change in the tapped and bulk densities under the different storage conditions over the storage period. No organoleptic changes were observed for any of the samples stored under the environmental conditions over the two-month period. All the tablets stored over the two- month period conformed to the official BP standard for weight uniformity. Paracetamol tablets exposed to 93% relative humidity (RH) showed significantly lower reduction (P<0.05) in hardness compared to the other storage conditions. On prolonged exposure of paracetamol and metronidazole tablets to radiation from telecommunication mast, there was a reduction in tablet hardness and the tablets became friable. The observations of the present study reconfirm the role of storage conditions in ensuring the physical stability of pharmaceutical powders and tablets.\Dhaka Univ. J. Pharm. Sci. 14(2): 147-151, 2015 (December)


Author(s):  
Avilash Carpenter ◽  
M.K. Gupta ◽  
Neetesh Kumar Jain ◽  
Urvashi Sharma ◽  
Rahul Sisodiya

Aim: The main of the study is to formulate and develop orally disintegrating fast dissolving tablet of Metoclopramide hydrochloride. Material & Methods: Before formulation and development of selected drug, the standard curve in buffer was prepared and absorbance at selected maxima was taken. Then two different disintegrating agents were selected and drug was mixed with disintegrating agents in different ratio. Various Preformulation parameters and evaluation of tablet i.e. disintegration time, dissolution time, friability, hardness, thickness were measured by standard procedure. Result & Discussion: The angle of repose for all the batches prepared. The values were found to be in the range of 30.46 to 36.45, which indicates good flow property for the powder blend according to the USP. The bulk density and tapped density for all the batches varied from 0.49 to 0.54 g/mL and 0.66 to 0.73, respectively. Carr’s index values were found to be in the range of 23.33 to 25.88, which is satisfactory for the powders as well as implies that the blends have good compressibility. Hausner ratio values obtained were in the range of 1.22 to 1.36, which shows a passable flow property for the powder blend based on the USP. The results for tablet thickness and height for all batches was found to range from 4.45 to 4.72 mm and 3.67 to 3.69 mm, respectively. Hardness or breaking force of tablets for all batches was found to range from 32.8 to 36.2 N. Tablet formulations must show good mechanical strength with sufficient hardness in order to handle shipping and transportation. Friability values for all the formulations were found to be in the range of 0.22 % to 0.30 %. Conclusion: Orally disintegrating tablets were compressed in order to have sufficient mechanical strength and integrity to withstand handling, shipping and transportation. The formulation was shown to have a rapid disintegration time that complied with the USP (less than one minute). The data obtained from the stability studies indicated that the orally disintegrating mini-tablets of MTH were stable under different environmental storage conditions. Keywords: Formulation & Development, Fast Dissolving Tablet, Metoclopramide, Anti-Emetic Drug, Oral Disintegrating Tablet


1964 ◽  
Vol 16 (11) ◽  
pp. 345-351 ◽  
Author(s):  
Edna M. Montgomery ◽  
K. R. Sexson ◽  
R. J. Dimler ◽  
F. R. Senti

2001 ◽  
Vol 34 (1) ◽  
pp. 25-30 ◽  
Author(s):  
E.R Farnworth ◽  
M Lagacé ◽  
R Couture ◽  
V Yaylayan ◽  
B Stewart

2017 ◽  
Vol 41 (1) ◽  
pp. e12607 ◽  
Author(s):  
Mona Aghazadeh ◽  
Roselina Karim ◽  
M. Tauseef Sultan ◽  
Maryam Paykary ◽  
Stuart K. Johnson ◽  
...  

2019 ◽  
Vol 119 ◽  
pp. 643-652 ◽  
Author(s):  
Silvani Verruck ◽  
Gabriela Rodrigues de Liz ◽  
Carolinne Odebrech Dias ◽  
Renata Dias de Mello Castanho Amboni ◽  
Elane Schwinden Prudencio

2020 ◽  
Vol 8 (3) ◽  
pp. 232-238
Author(s):  
Dawn C.P. Ambrose

Multiplier onion (Allium cepa L. var aggregatum. Don.) is mainly used for its unique flavour in seasoning dishes. The unpeeled onions are processed at farm level by means of primary processing and by secondary processing various products like paste, flakes, powder could be produced from peeled onions. For the design of processing and handling equipment knowledge of engineering properties is essential. The engineering properties of peeled and unpeeled multiplier onion were determined. The average values of the physical properties of unpeeled onion were recorded for bulk density and true density as 636.621 and 1526.825 kg/m3 respectively. Similarly for peeled onions, the bulk and true density were 627.03 and 1108.74 kg/m3 respectively. The moisture present in peeled and unpeeled onion was 77.66 % and 74.43% (w.b) respectively. The TSS of multiplier onion was found to be 20° Brix for both peeled and unpeeled samples. The colour values were also measured using colour flex meter for the peeled and unpeeled onions. The frictional properties including coefficient of friction, filling and emptying angle of repose were also measured. Mechanical properties were determined by using a texture analyser. The firmness was measured in terms of penetrating force and crushing strength which were recorded to be 8.59 N and 124.93 N respectively for peeled and 12.00 N and 138.35 N respectively for unpeeled onions.


Polymers ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1084 ◽  
Author(s):  
Daniel Domene-López ◽  
Juan Carlos García-Quesada ◽  
Ignacio Martin-Gullon ◽  
Mercedes G. Montalbán

Thermoplastic starch (TPS) films are considered one of the most promising alternatives for replacing synthetic polymers in the packaging field due to the starch biodegradability, low cost, and abundant availability. However, starch granule composition, expressed in terms of amylose content and phosphate monoesters, and molecular weight of starch clearly affects some film properties. In this contribution, biodegradable TPS films made from potato, corn, wheat, and rice starch were prepared using the casting technique. The effect of the grain structure of each starch on microstructure, transparency, hydration properties, crystallinity, and mechanical properties of the films, was evaluated. Potato starch films were the most transparent and corn starch films the most opaque. All the films had homogeneous internal structures—highly amorphous and with no pores, both of which point to a good starch gelatinization process. The maximum tensile strength (4.48–8.14 MPa), elongation at break (35.41–100.34%), and Young’s modulus (116.42–294.98 MPa) of the TPS films were clearly influenced by the amylose content, molecular weight, and crystallinity of the film. In this respect, wheat and corn starch films, are the most resistant and least stretchable, while rice starch films are the most extensible but least resistant. These findings show that all the studied starches can be considered suitable for manufacturing resistant and flexible films with similar properties to those of synthetic low-density polyethylene (LDPE), by a simple and environmentally-friendly process.


Sign in / Sign up

Export Citation Format

Share Document